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Report error Found 12 Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase G'
TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 10nMAssay Description:Inhibition of PPIG (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  11nMAssay Description:Binding affinity against PPIG (unknown origin) assessed as apparent dissociation constant incubated for 1 hr by colloidal coomassie staining based LC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM140005(US8901295, F684)
Affinity DataIC50: 370nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM140004(US8901295, F680)
Affinity DataIC50: 560nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM140008(US8901295, F716)
Affinity DataIC50: 790nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM140002(US8901295, F671)
Affinity DataIC50: 1.50E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM140001(US8901295, F609)
Affinity DataIC50: 2.80E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM140007(US8901295, F714)
Affinity DataIC50: 3.10E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM140006(US8901295, F712)
Affinity DataIC50: 3.30E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM140003(US8901295, F673)
Affinity DataIC50: 3.40E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM46034(US8901295, F607)
Affinity DataIC50: 9.00E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase G(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)
Affinity DataIC50: 1.68E+4nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent