Compile Data Set for Download or QSAR
Report error Found 149 Enz. Inhib. hit(s) with Target = 'Peroxisomal N(1)-acetyl-spermine/spermidine oxidase'
LigandPNGBDBM50015358(N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE-DIAMINE | CHEM...)
Affinity DataKi:  90nMAssay Description:Inhibitory activity measured as apparent dissociation constant against Polyamine oxidase (PAO) from pig liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50405943(CHEMBL176596)
Affinity DataKi:  96nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50405931(CHEMBL367753)
Affinity DataKi:  100nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM152706(Chlorhexidine (1) | Chlorhexidine)
Affinity DataKi:  100nM ΔG°:  -40.0kJ/molepH: 7.5 T: 2°CAssay Description:The APAO and SMO activities were measured spectrophotometrically by following the formation of a pink adduct (ε515 nm = 2.6 × 10^4 M−1 cm&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details Article
PubMed
LigandPNGBDBM50405937(CHEMBL173782)
Affinity DataKi:  180nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50026232(N-Buta-2,3-dienyl-N'-methyl-butane-1,4-diamine | C...)
Affinity DataKi:  300nMAssay Description:Inhibitory activity measured as apparent dissociation constant against Polyamine oxidase (PAO) from pig liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50405942(CHEMBL175345)
Affinity DataKi:  630nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50026231(N*1*-Buta-2,3-dienyl-butane-1,4-diamine | CHEMBL59...)
Affinity DataKi:  700nMAssay Description:Inhibitory activity measured as apparent dissociation constant against Polyamine oxidase (PAO) from pig liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50405939(CHEMBL175307)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisomal N(1)-acetyl-spermine/spermidine oxidase(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015358(N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE-DIAMINE | CHEM...)
Affinity DataKi:  1.70E+3nMAssay Description:Tested for in vitro binding affinity against polyamine oxidase after intraperitoneal administration in the rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50018055(CHEMBL176843 | 7-Amino-heptan-2-one)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisomal N(1)-acetyl-spermine/spermidine oxidase(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50368113(CHEMBL1202500)
Affinity DataKi:  2.50E+3nMAssay Description:Tested for in vitro binding affinity against polyamine oxidase after intraperitoneal administration in the rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetPeroxisomal N(1)-acetyl-spermine/spermidine oxidase(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015357(CHEMBL287672 | Buta-2,3-dienyl-[3-(3-buta-2,3-dien...)
Affinity DataKi:  3.00E+3nMAssay Description:Tested for in vitro binding affinity against polyamine oxidase after intraperitoneal administration in the rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM741191(US20250161307, Example 34)
Affinity DataIC50: 1.10E+4nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741183(US20250161307, Example 26)
Affinity DataIC50: 2.20E+4nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM50405932(CHEMBL176530)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50405935(CHEMBL177305)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM741182(US20250161307, Example 25)
Affinity DataIC50: 3.50E+4nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741184(US20250161307, Example 27)
Affinity DataIC50: 4.90E+4nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM50405928(CHEMBL174669)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM741185(US20250161307, Example 28)
Affinity DataIC50: 8.50E+4nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741274(US20250161307, Example 118)
Affinity DataIC50: 1.03E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM50405940(CHEMBL177890)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM741272(US20250161307, Example 116)
Affinity DataIC50: 1.19E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741238(US20250161307, Example 81)
Affinity DataIC50: 1.23E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741187(US20250161307, Example 30)
Affinity DataIC50: 1.29E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM50405930(CHEMBL174887)
Affinity DataKi:  1.30E+5nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM741257(US20250161307, Example 101)
Affinity DataIC50: 1.81E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741273(US20250161307, Example 117)
Affinity DataIC50: 1.97E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741271(US20250161307, Example 115)
Affinity DataIC50: 2.13E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741169(US20250161307, Example 12)
Affinity DataIC50: 2.33E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM50405934(CHEMBL176764)
Affinity DataKi:  2.60E+5nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM741237(US20250161307, Example 80)
Affinity DataIC50: 2.89E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741239(US20250161307, Example 82)
Affinity DataIC50: 2.91E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741177(US20250161307, Example 20)
Affinity DataIC50: 3.06E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741176(US20250161307, Example 19)
Affinity DataIC50: 3.07E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM50026230(N-Methyl-N'-prop-2-ynyl-butane-1,4-diamine | CHEMB...)
Affinity DataKi:  3.10E+5nMAssay Description:Inhibitory activity measured as apparent dissociation constant against Polyamine oxidase (PAO) from pig liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM741192(US20250161307, Example 35)
Affinity DataIC50: 3.62E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM50405929(CHEMBL436093)
Affinity DataKi:  3.76E+5nMAssay Description:Inhibition of deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM741244(US20250161307, Example 87)
Affinity DataIC50: 3.87E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741104(US20250161307, Example 1)
Affinity DataIC50: 3.97E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM50026233(N*1*-Prop-2-ynyl-butane-1,4-diamine | CHEMBL292770)
Affinity DataKi:  4.25E+5nMAssay Description:Inhibitory activity measured as apparent dissociation constant against Polyamine oxidase (PAO) from pig liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM741265(US20250161307, Example 109)
Affinity DataIC50: 4.70E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741262(US20250161307, Example 106)
Affinity DataIC50: 4.85E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741249(US20250161307, Example 92)
Affinity DataIC50: 5.20E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741179(US20250161307, Example 22)
Affinity DataIC50: 5.35E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741234(US20250161307, Example 77)
Affinity DataIC50: 5.44E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741259(US20250161307, Example 103)
Affinity DataIC50: 5.47E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741277(US20250161307, Example 121)
Affinity DataIC50: 6.41E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

LigandPNGBDBM741250(US20250161307, Example 93)
Affinity DataIC50: 6.43E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

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