Compile Data Set for Download or QSAR
Report error Found 159 Enz. Inhib. hit(s) with Target = 'Phosphorylase b kinase gamma catalytic chain, liver/testis isoform'
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PHKgamma2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  0.140nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  0.140nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  0.140nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.336nMAssay Description:Inhibition of human PHKgamma2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of PHKg2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of human PHKgamma2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1nMAssay Description:Average Binding Constant for PHkg2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to PHKG2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  1.70nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human PHKg2 using KKLNRTLSFAEPG as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  5.90nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  5.90nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  5.90nMAssay Description:Binding affinity to PHKG2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  5.90nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of PhKg2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataKd:  13nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  18nMAssay Description:Binding affinity to human PHKG2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  39nMAssay Description:Average Binding Constant for PHkg2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  39nMAssay Description:Inhibition of PHKG2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  71nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PHKG2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50505542(CHEMBL4576489)
Affinity DataKd:  72nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PHKG2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  100nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  100nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  100nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 108nMAssay Description:Inhibition of human PHKg2 using KKLNRTLSFAEPG as substrate in presence of [gamma33P]-ATP by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  139nMAssay Description:Binding affinity to human PHKG2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  140nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50204290(CHEMBL3979920 | US11077111, Compound IIIa | US2023...)
Affinity DataIC50: 226nMAssay Description:Inhibition of human recombinant full length N-terminal GST-tagged PHKG2 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2018
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  260nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd:  460nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Affinity DataKd:  470nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50024294(SP-600125)
Affinity DataKd:  480nMAssay Description:Average Binding Constant for PHkg2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50395272(CHEMBL1231206)
Affinity DataIC50: 528nMAssay Description:Inhibition of PhKgamma2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  760nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50020310(CHEMBL3288854)
Affinity DataKi:  840nMAssay Description:Binding affinity to PHKgamma2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  900nMAssay Description:Binding affinity to PHKG2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  940nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PHKG2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PHK-gamma2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PHKG2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  1.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd:  1.60E+3nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  1.60E+3nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PHKgamma2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Displayed 1 to 50 (of 159 total ) | Next | Last >>
Jump to: