Report error Found 7394 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1'
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0220nMAssay Description:Inhibition of PARP1 (unknown origin) using histone/NAD+ as substrates by NAD/NADH-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0230nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0610nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PARP1 (unknown origin) using histone/NAD+ as substrates by NAD/NADH-Glo assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMpH: 8.0Assay Description:PARP1 assay was conducted in PARP assay buffer containing 50 mM Tris pH 8.0, 1 mM DTT, 4 mM MgCl2. PARP reactions contained 1.5 uM [3H]-NAD+ (1.6 uCi...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMpH: 8.0Assay Description:PARP1 assay was conducted in PARP assay buffer containing 50 mM Tris pH 8.0, 1 mM DTT, 4 mM MgCl2. PARP reactions contained 1.5 uM [3H]-NAD+ (1.6 uCi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate incubated for 45 mins by absorbance based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.150nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.150nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.160nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.170nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.175nMAssay Description:Inhibition of C-terminal His-tagged human recombinant PARP-1 (1 to 1014 residues) expressed in Sf9 insect cells incubated for 1 hr by 32P-NAD+-based ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Inhibition of PARP-1 in human HeLa cells incubated for 18 hrs in presence of H2O2More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMT: 2°CAssay Description:Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.230nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.230nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.240nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKd: 0.240nMAssay Description:Binding affinity to recombinant human HisGST-tagged PARP-1 catalytic domain by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human PARP-1 by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 0.25nMAssay Description:Inhibition of PARP-1 (unknown origin) using biotinylated NAD+ as substrate incubated for 45 mins in the presence of deoxy-oligonucleotide by micropla...More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.260nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.260nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.280nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.280nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.290nMAssay Description:Table 1: PARP1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair











3D Structure (crystal)

































