Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily B member 1'
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641544(CHEMBL5574868)
Affinity DataIC50: 50nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641537(CHEMBL5573337)
Affinity DataIC50: 70nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641542(CHEMBL5566791)
Affinity DataIC50: 80nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641541(CHEMBL5549888)
Affinity DataIC50: 250nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641540(CHEMBL5570192)
Affinity DataIC50: 300nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641536(CHEMBL5574133)
Affinity DataIC50: 320nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641543(CHEMBL5570536)
Affinity DataIC50: 320nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641539(CHEMBL5570619)
Affinity DataIC50: 337nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641538(CHEMBL5569315)
Affinity DataIC50: 370nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641514(CHEMBL5590036)
Affinity DataIC50: 390nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641521(CHEMBL5574578)
Affinity DataIC50: 430nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641545(CHEMBL5570316)
Affinity DataIC50: 430nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641517(CHEMBL5565837)
Affinity DataIC50: 480nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641520(CHEMBL5563908)
Affinity DataIC50: 530nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641511(CHEMBL5574392)
Affinity DataIC50: 540nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641529(CHEMBL5571030)
Affinity DataIC50: 550nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641522(CHEMBL5571436)
Affinity DataIC50: 590nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50088573(CHEMBL3577208)
Affinity DataIC50: 590nMAssay Description:Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641535(CHEMBL5565317)
Affinity DataIC50: 660nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641546(CHEMBL5566632)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641512(CHEMBL5567049)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641518(CHEMBL5565614)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641516(CHEMBL5574881)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641515(CHEMBL5574434)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641547(CHEMBL5572478)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641526(CHEMBL5572336)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641525(CHEMBL5573624)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641524(CHEMBL5575047)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641523(CHEMBL5570294)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50088572(CHEMBL3577209)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641534(CHEMBL5575379)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641532(CHEMBL5595709)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641528(CHEMBL5571104)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641531(CHEMBL5565130)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641519(CHEMBL5583837)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641513(CHEMBL5590132)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50213095((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641530(CHEMBL5573843)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641527(CHEMBL5568884)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50641533(CHEMBL5565384)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human KV2.1 stably expressed in HEK293 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM168436(US9675591, SKA-19)
Affinity DataEC50:  2.23E+4nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2018
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily B member 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50593373(CHEMBL5182581)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of Kv2.1 channel (unknown origin) by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed