Compile Data Set for Download or QSAR
Report error Found 203 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily KQT member 1'
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279436BDBM50279436(1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106179BDBM50106179(Enantiomer-4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(2,...)
Affinity DataIC50: 2nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279740BDBM50279740(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279471BDBM50279471(1-(2,3-dihydro-6-chlorochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106169BDBM50106169(Enantiomer-4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(2,...)
Affinity DataIC50: 9nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279454BDBM50279454(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106167BDBM50106167(Enantiomer-4-(3-Cyclopropylmethyl-[1,2,4]oxadiazol...)
Affinity DataIC50: 18nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106167BDBM50106167(Enantiomer-4-(3-Cyclopropylmethyl-[1,2,4]oxadiazol...)
Affinity DataIC50: 18nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 710452BDBM710452(1-(3-methyl-1- bicyclo[1.1.1]pentanyl)-3- [(1S)-1-...)
Affinity DataEC50:  20nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279703BDBM50279703(1-(6-butoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 22nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106178BDBM50106178(4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(3,3-dimethyl-...)
Affinity DataIC50: 23nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106168BDBM50106168(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-(3...)
Affinity DataIC50: 27nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106168BDBM50106168(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-(3...)
Affinity DataIC50: 27nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279453BDBM50279453(1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 27nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 710476BDBM710476(1-(3-fluoro-1- bicyclo[1.1.1]pentanyl)-3- [[3- (tr...)
Affinity DataEC50:  30nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061218BDBM50061218((E)-3-(2,4-Dichloro-phenyl)-N-((R)-1-methyl-2-oxo-...)
Affinity DataIC50: 31nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 710453BDBM710453(1-(3-propan-2-yl-1- bicyclo[1.1.1]pentanyl)-3- [(1...)
Affinity DataEC50:  40nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106176BDBM50106176(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-[5...)
Affinity DataIC50: 40nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 710461BDBM710461(1-[dideuterio-[3- (trifluoromethoxy)phenyl] methyl...)
Affinity DataEC50:  40nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710461BDBM710461(1-[dideuterio-[3- (trifluoromethoxy)phenyl] methyl...)
Affinity DataEC50:  40nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106176BDBM50106176(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-[5...)
Affinity DataIC50: 40nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 710460BDBM710460(1-[[3- (fluoromethoxy)phenyl] methyl]-3-[3-(triflu...)
Affinity DataEC50:  50nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710438BDBM710438(1-[(1R)-1-(3-bromophenyl)- 2-hydroxyethyl]-3-[3- (...)
Affinity DataEC50:  50nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710436BDBM710436(1-(3-fluoro-1- bicyclo[1.1.1]pentanyl)-3- [(1S)-1-...)
Affinity DataEC50:  60nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710484BDBM710484(1-[[3-(2,2,2- trifluoroethoxy)phenyl] methyl]-3-[3...)
Affinity DataEC50:  60nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710463BDBM710463(1-(1- bicyclo[1.1.1]pentanyl)-3- [1-[3- (trifluoro...)
Affinity DataEC50:  60nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710474BDBM710474(1-[(1R)-2-hydroxy-1-[3- (trifluoromethyl)phenyl] e...)
Affinity DataEC50:  60nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710435BDBM710435(1-(3-fluoro-1- bicyclo[1.1.1]pentanyl)-3- [(1S)-1-...)
Affinity DataEC50:  70nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710451BDBM710451(1-(1- bicyclo[1.1.1]pentanyl)-3- [(1S)-1-[3- (trif...)
Affinity DataEC50:  70nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710433BDBM710433(1-[3-(trifluoromethyl)-1- bicyclo[1.1.1]pentanyl]-...)
Affinity DataEC50:  70nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710462BDBM710462(1-[(3-bromophenyl)methyl]- 3-[3-(trifluoromethyl)-...)
Affinity DataEC50:  70nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279717BDBM50279717(1-(2,3-dihydro-6-chlorochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 73nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 710481BDBM710481(1-[(1R)-2-hydroxy-1-[3- (trifluoromethoxy)phenyl] ...)
Affinity DataEC50:  80nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710446BDBM710446(1-(3-methyl-1- bicyclo[1.1.1]pentanyl)-3- [[3- (tr...)
Affinity DataEC50:  80nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710428BDBM710428(1-[[3- (trifluoromethoxy)phenyl] methyl]-3-[3- (tr...)
Affinity DataEC50:  80nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710455BDBM710455(1-[[3- (difluoromethoxy)phenyl] methyl]-3-[3- (tri...)
Affinity DataEC50:  80nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710455BDBM710455(1-[[3- (difluoromethoxy)phenyl] methyl]-3-[3- (tri...)
Affinity DataEC50:  80nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710442BDBM710442(1-[(1S)-1-(3- bromophenyl)ethyl]-3-(3- fluoro-1- b...)
Affinity DataEC50:  90nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710483BDBM710483(1-[[2-fluoro-3- (trifluoromethoxy)phenyl] methyl]-...)
Affinity DataEC50:  100nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710458BDBM710458(1-[(3- ethynylphenyl)methyl]-3-[3- (trifluoromethy...)
Affinity DataEC50:  100nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710472BDBM710472(1-(3-methyl-1- bicyclo[1.1.1]pentanyl)-3- [[3- (tr...)
Affinity DataEC50:  100nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099582BDBM50099582(N-[(3R,4S)-3-Hydroxy-2,2-dimethyl-6-(4,4,4-trifluo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 710447BDBM710447(1-(3-propan-2-yl-1- bicyclo[1.1.1]pentanyl)-3- [[3...)
Affinity DataEC50:  120nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106182BDBM50106182(N-(3,3-Dimethyl-butyl)-4-(3-phenyl-[1,2,4]oxadiazo...)
Affinity DataIC50: 130nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 710448BDBM710448(1-[3-(difluoromethyl)-1- bicyclo[1.1.1]pentanyl]-3...)
Affinity DataEC50:  160nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710464BDBM710464(1-[1-[3- (difluoromethoxy)phenyl] ethyl]-3-(3-fluo...)
Affinity DataEC50:  180nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710473BDBM710473(1-[(3-cyano-2- fluorophenyl)methyl]-3-[3- (trifluo...)
Affinity DataEC50:  210nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710477BDBM710477(1-(1- bicyclo[1.1.1]pentanyl)-3- [(1S)-1-[3- (trif...)
Affinity DataEC50:  230nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710437BDBM710437(1-(3-fluoro-1- bicyclo[1.1.1]pentanyl)-3- [[3- (tr...)
Affinity DataEC50:  240nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710478BDBM710478(1-[(3-cyanophenyl)- dideuteriomethyl]-3-[3- (trifl...)
Affinity DataEC50:  240nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

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