Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily KQT member 3/5'
LigandChemical structure of BindingDB Monomer ID 50465779BDBM50465779(CHEMBL4278049)
Affinity DataEC50:  80nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50465777BDBM50465777(CHEMBL4288707)
Affinity DataEC50:  200nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50465773BDBM50465773(CHEMBL4277250)
Affinity DataEC50:  250nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50465774BDBM50465774(CHEMBL4287894)
Affinity DataEC50:  360nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50465778BDBM50465778(CHEMBL4287478)
Affinity DataEC50:  400nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50465775BDBM50465775(CHEMBL1703636)
Affinity DataEC50:  500nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50420049BDBM50420049(CHEMBL402146)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 697199BDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697213BDBM697213(US20240316020, Example 28 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697212BDBM697212(US20240316020, Example 27 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697210BDBM697210(US20240316020, Example 25 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697209BDBM697209(US20240316020, Example 24 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697208BDBM697208(US20240316020, Example 23 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697206BDBM697206(US20240316020, Example 21 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697204BDBM697204(US20240316020, Example 19 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697199BDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent