Compile Data Set for Download or QSAR
Report error Found 1167 Enz. Inhib. hit(s) with Target = 'Protein mono-ADP-ribosyltransferase PARP14'
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM434315(US10562891, Example 235 | US11008308, Example 235)
Affinity DataIC50: 3nMAssay Description:Inhibition of human PARP14 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM434315(US10562891, Example 235 | US11008308, Example 235)
Affinity DataIC50: 3nMAssay Description:Inhibition of PARP14 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM434315(US10562891, Example 235 | US11008308, Example 235)
Affinity DataIC50: 3nMAssay Description:Displacement of a biotinylated small molecule probe from human PARP14 catalytic domain incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594259(CHEMBL5180081)
Affinity DataIC50: 10nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM434254(US10562891, Example 176 | US11008308, Example 176)
Affinity DataIC50: 19nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594258(CHEMBL5178541)
Affinity DataIC50: 76nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50: 160nMAssay Description:Inhibition of full length recombinant His6-tagged PARP14 catalytic domain (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242653(CHEMBL4074448)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242653(CHEMBL4074448)
Affinity DataIC50: 275nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616441(CHEMBL5404785)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP14 (unknown origin) expressed in Escherichia coli in presence of NAD+ by proximity enhanced assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM434101(US10562891, Example 23 | US11008308, Example 23)
Affinity DataIC50: 300nMAssay Description:Inhibition of PARP14 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594256(CHEMBL5196898)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]NAD+ from GST-tagged PARP14 (unknown origin) incubated for 210 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242657(CHEMBL4104938)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242657(CHEMBL4104938)
Affinity DataIC50: 372nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50: 407nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242654(CHEMBL4104503)
Affinity DataIC50: 447nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242654(CHEMBL4104503)
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594244(CHEMBL5205408)
Affinity DataIC50: 490nMAssay Description:Inhibition of PARP14 (unknown origin) expressed in bacterial expression system using histone substrate incubated for 60 mins by chemiluminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50460988(CHEMBL4226482)
Affinity DataKd:  550nMAssay Description:Binding affinity to PARP14 MD2 (A994 to N1191 residues) (unknown origin) expressed in bacterial expression system by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594255(CHEMBL5199759)
Affinity DataIC50: 580nMAssay Description:Displacement of [3H]NAD+ from GST-tagged PARP14 (unknown origin) incubated for 210 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594257(CHEMBL5191979)
Affinity DataIC50: 610nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50468597(CHEMBL4293771)
Affinity DataIC50: 630nMAssay Description:Inhibition of PARP14 (unknown origin) using NAD+ as substrate incubated for 18 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242655(CHEMBL4080281)
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616435(CHEMBL5431108)
Affinity DataIC50: 650nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP14 (unknown origin) expressed in Escherichia coli in presence of NAD+ by proximity enhanced assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50460988(CHEMBL4226482)
Affinity DataIC50: 660nMAssay Description:Displacement of ARTK(Bio)QTARK(Aoa-RADP)S from His6-tagged PARP14 MD2 (A994 to N1191 residues) (unknown origin) expressed in bacterial expression sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242655(CHEMBL4080281)
Affinity DataIC50: 676nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50: 692nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50272968(CHEMBL4126260)
Affinity DataIC50: 692nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50272968(CHEMBL4126260)
Affinity DataIC50: 700nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50: 700nMAssay Description:Inhibition of full length recombinant His6-tagged PARP14 catalytic domain (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50: 708nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50461016(CHEMBL4226393)
Affinity DataIC50: 710nMAssay Description:Inhibition of PARP14 MD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50461016(CHEMBL4226393)
Affinity DataIC50: 720nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50461016(CHEMBL4226393)
Affinity DataIC50: 720nMAssay Description:Displacement of ARTK(Bio)QTARK(Aoa-RADP)S from His6-tagged PARP14 MD2 (A994 to N1191 residues) (unknown origin) expressed in bacterial expression sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594245(CHEMBL5186947)
Affinity DataIC50: 760nMAssay Description:Inhibition of PARP14 (unknown origin) expressed in bacterial expression system using histone substrate incubated for 60 mins by chemiluminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594246(CHEMBL5181342)
Affinity DataIC50: 770nMAssay Description:Inhibition of PARP14 (unknown origin) expressed in bacterial expression system using histone substrate incubated for 60 mins by chemiluminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50272955(CHEMBL4129001)
Affinity DataIC50: 776nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50272955(CHEMBL4129001)
Affinity DataIC50: 780nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50461016(CHEMBL4226393)
Affinity DataKd:  860nMAssay Description:Binding affinity to PARP14 MD2 (A994 to N1191 residues) (unknown origin) expressed in bacterial expression system by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242660(CHEMBL4087082)
Affinity DataIC50: 891nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50242660(CHEMBL4087082)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50460999(CHEMBL4226081)
Affinity DataIC50: 900nMAssay Description:Displacement of ARTK(Bio)QTARK(Aoa-RADP)S from His6-tagged PARP14 MD2 (A994 to N1191 residues) (unknown origin) expressed in bacterial expression sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50461015(CHEMBL4228040)
Affinity DataIC50: 900nMAssay Description:Displacement of ARTK(Bio)QTARK(Aoa-RADP)S from His6-tagged PARP14 MD2 (A994 to N1191 residues) (unknown origin) expressed in bacterial expression sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50594250(CHEMBL5207717)
Affinity DataIC50: 917nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14 [1611-1801](Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM434113(US10562891, Example 35 | US11008308, Example 35)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

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