Compile Data Set for Download or QSAR
Report error Found 128 Enz. Inhib. hit(s) with Target = 'Relaxin receptor 1'
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599229(CHEMBL5194101)
Affinity DataEC50:  0.000410nMAssay Description:Modulation of human RXFP1 stably expressed in T-REx-CHO-K1 cells assessed as stimulation of cAMP production measured after 45 mins by d2-dye labelled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599230(CHEMBL5198814)
Affinity DataEC50:  0.000490nMAssay Description:Modulation of human RXFP1 stably expressed in T-REx-CHO-K1 cells assessed as stimulation of cAMP production measured after 45 mins by d2-dye labelled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599232(CHEMBL5206759)
Affinity DataEC50:  0.000700nMAssay Description:Modulation of human RXFP1 stably expressed in T-REx-CHO-K1 cells assessed as stimulation of cAMP production measured after 45 mins by d2-dye labelled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599233(CHEMBL5197919)
Affinity DataEC50:  0.00150nMAssay Description:Modulation of human RXFP1 stably expressed in T-REx-CHO-K1 cells assessed as stimulation of cAMP production measured after 45 mins by d2-dye labelled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599228(CHEMBL5179696)
Affinity DataEC50: <0.00200nMAssay Description:Modulation of human RXFP1 stably expressed in T-REx-CHO-K1 cells assessed as stimulation of cAMP production measured after 45 mins by d2-dye labelled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599231(CHEMBL5208579)
Affinity DataEC50:  0.00250nMAssay Description:Modulation of human RXFP1 stably expressed in T-REx-CHO-K1 cells assessed as stimulation of cAMP production measured after 45 mins by d2-dye labelled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563230(CHEMBL4754949)
Affinity DataEC50:  0.0324nMAssay Description:Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563226(CHEMBL4745611)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563225(CHEMBL4795810)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563227(CHEMBL4786789)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563230(CHEMBL4754949)
Affinity DataEC50:  0.420nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Rat)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563230(CHEMBL4754949)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563223(CHEMBL4799907)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Rat)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563220(CHEMBL4793799)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563222(CHEMBL4797641)
Affinity DataEC50:  1nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563224(CHEMBL4764326)
Affinity DataEC50:  1nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563230(CHEMBL4754949)
Affinity DataKi:  1.10nMAssay Description:Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563221(CHEMBL4752287)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563220(CHEMBL4793799)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Rat)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563215(CHEMBL4781560)
Affinity DataEC50:  5.30nMAssay Description:Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563223(CHEMBL4799907)
Affinity DataEC50:  9nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563215(CHEMBL4781560)
Affinity DataEC50:  12nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM719072(2-(6-fluoro-3'-(((1S,5R,6S,7R)-7-((4-fluoro-3-(tri...)
Affinity DataEC50:  12nMAssay Description:Human embryonic kidney cells 293 (HEK293) cells and HEK293 cells stably expressing human RXFP1, were cultured in MEM medium supplemented with 10% qua...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563212(CHEMBL4784237)
Affinity DataEC50:  14nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563214(CHEMBL4761130)
Affinity DataEC50:  14nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563209(CHEMBL4777259)
Affinity DataEC50:  17nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563198(CHEMBL4743539)
Affinity DataEC50:  17nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563225(CHEMBL4795810)
Affinity DataEC50:  18nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563210(CHEMBL4779982)
Affinity DataEC50:  18nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563218(CHEMBL4744987)
Affinity DataEC50:  18nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563219(CHEMBL4797258)
Affinity DataEC50:  18nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563191(CHEMBL4748931)
Affinity DataEC50:  20nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563226(CHEMBL4745611)
Affinity DataEC50:  20nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563213(CHEMBL4755239)
Affinity DataEC50:  23nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563227(CHEMBL4786789)
Affinity DataEC50:  25nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563222(CHEMBL4797641)
Affinity DataEC50:  31nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563196(CHEMBL4791290)
Affinity DataEC50:  32nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563216(CHEMBL4788675)
Affinity DataEC50:  32nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563208(CHEMBL4748601)
Affinity DataEC50:  37nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563211(CHEMBL4739969)
Affinity DataEC50:  43nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563189(CHEMBL4748830)
Affinity DataEC50:  45nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563217(CHEMBL4781139)
Affinity DataEC50:  45nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563199(CHEMBL4756139)
Affinity DataEC50:  46nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50449861(CHEMBL3715081)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50010261(colforsinum | cid_47936 | colforsina | colforsine ...)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50449846(CHEMBL3715235)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563204(CHEMBL4791486)
Affinity DataEC50:  54nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50449859(CHEMBL3718400)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563224(CHEMBL4764326)
Affinity DataEC50:  87nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetRelaxin receptor 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563205(CHEMBL4785899)
Affinity DataEC50:  92nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
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