Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1 [17-535]'
TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 97666BDBM97666(US8476295, 1.1.04)
Affinity DataKi:  35nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase 1 activity was determined using the IMAP™ Screening Express Kit (Molecular Devices product number #80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 97665BDBM97665(US8476295, 1.1.03)
Affinity DataKi:  59nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase 1 activity was determined using the IMAP™ Screening Express Kit (Molecular Devices product number #80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 97663BDBM97663(US8476295, 1.1.01)
Affinity DataKi:  72nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase 1 activity was determined using the IMAP™ Screening Express Kit (Molecular Devices product number #80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 97664BDBM97664(US8476295, 1.1.02)
Affinity DataKi:  91nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase 1 activity was determined using the IMAP™ Screening Express Kit (Molecular Devices product number #80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 97667BDBM97667(US8476295, 2.1.01)
Affinity DataKi:  806nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase 1 activity was determined using the IMAP™ Screening Express Kit (Molecular Devices product number #80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 97668BDBM97668(US8476295, 3.1.01)
Affinity DataKi:  976nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase 1 activity was determined using the IMAP™ Screening Express Kit (Molecular Devices product number #80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 362931BDBM362931(US9849138, 5)
Affinity DataIC50: 1.00E+7nMAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 362930BDBM362930(US9849138, 4)
Affinity DataIC50: 1.00E+7nMAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 362926BDBM362926(US9849138, 2)
Affinity DataIC50: 1.00E+7nMAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 362925BDBM362925(US9849138, 1)
Affinity DataIC50: 3.00E+7nMAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1 [17-535](Human)
Inspire

US Patent
LigandChemical structure of BindingDB Monomer ID 362928BDBM362928(US9849138, 3)
Affinity DataIC50: 3.00E+7nMAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent