Compile Data Set for Download or QSAR
Report error Found 2451 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1'
TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182699(US9145392, 400)
Affinity DataIC50: 0.0600nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182489(US9145392, 190)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182480(US9145392, 181)
Affinity DataIC50: 0.110nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116503(US8637532, 184)
Affinity DataIC50: 0.120nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116504(US8637532, 185)
Affinity DataIC50: 0.140nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182551(US9145392, 252)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182671(US9145392, 372)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM117011(US8637532, 738)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182483(US9145392, 184)
Affinity DataIC50: 0.260nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116505(US8637532, 186)
Affinity DataIC50: 0.280nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116506(US8637532, 187)
Affinity DataIC50: 0.360nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116507(US8637532, 188)
Affinity DataIC50: 0.390nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182673(US9145392, 374)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116509(US8637532, 190)
Affinity DataIC50: 0.420nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116508(US8637532, 189)
Affinity DataIC50: 0.420nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human p70S6K using KKRNRTLTK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182473(US9145392, 174)
Affinity DataIC50: 0.440nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182535(US9145392, 236)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182425(US9145392, 126)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116321(US8637532, 2)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182624(US9145392, 325)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116435(US8637532, 116)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116440(US8637532, 121)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116510(US8637532, 193)
Affinity DataIC50: 0.530nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116511(US8637532, 194)
Affinity DataIC50: 0.550nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.553nMAssay Description:Inhibition of human p70S6K using KKRNRTLTK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116512(US8637532, 195)
Affinity DataIC50: 0.580nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182586(US9145392, 287)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM117012(US8637532, 739)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116384(US8637532, 65)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182470(US9145392, 171)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182517(US9145392, 218)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116324(US8637532, 5)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182305(US9145392, 6)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116513(US8637532, 196)
Affinity DataIC50: 0.610nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116514(US8637532, 197)
Affinity DataIC50: 0.650nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116515(US8637532, 199)
Affinity DataIC50: 0.660nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116517(US8637532, 202)
Affinity DataIC50: 0.680nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116516(US8637532, 201)
Affinity DataIC50: 0.680nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182409(US9145392, 110)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116415(US8637532, 96)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182421(US9145392, 122)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182481(US9145392, 182)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116518(US8637532, 204)
Affinity DataIC50: 0.720nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182462(US9145392, 163)
Affinity DataIC50: 0.730nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of p70S6K (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116519(US8637532, 205)
Affinity DataIC50: 0.790nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182504(US9145392, 205)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182536(US9145392, 237)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182615(US9145392, 316)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

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