Report error Found 709 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4'
Affinity DataKi: 2.80nM EC50: 0.940nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PAK4 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PAK4 expressed in TR-293-KDG cells assessed as inhibition of GEFH1 phosphorylation at S180 using GEFH1 as substrate incubated for...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.30nMAssay Description:Inhibition of PAK4 Kinase domain (291 to 591 residues) (unknown origin) transfected in TR-293-KDG cells using GEFH1 as substrate assessed as inhibiti...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 8.80nM EC50: 1.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human N-terminal GST-fused PAK4 (1 to 591 residues) expressed in baculovirus expression system using S2 as substrate measur...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM EC50: 3nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 170nM EC50: 2.40nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 14nM EC50: 2.5nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human PAK4 using RRRLSFAEPG as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins by r...More data for this Ligand-Target Pair
Affinity DataKd: 2.70nMAssay Description:Binding affinity to human PAK4 (300 to 591 residues) assessed as dissociation constant by isothermal calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.70nMAssay Description:Binding affinity to PAK4 catalytic domain (unknown origin) assessed as equilibrium dissociation constant at 50 uM by ITC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human PAK4 assessed as enzymatic activity incubated for 20 mins by filter binding methodMore data for this Ligand-Target Pair
Affinity DataKd: 2.70nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant PAK4 (300 to 591 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of human PAK4 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of human recombinant PAK4 assessed as inhibition constant incubated for 10 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of human recombinant PAK4 using KKRNRRLSVA as substrate assessed as inhibition constant preincubated with compound for 10 mins followed by...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PAK4 kinase domain expressed in Escherichia coli using KKRNRRLSVA as substrate preincubat...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nM EC50: 19nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nM EC50: 19nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 40nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 8.30nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 20nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 39nM EC50: >3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 170nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human recombinant PAK4 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Inhibition of PAK4 in mouse NIH3T3 cells assessed as reduction in phosphorylated GEF-H1 accumulation incubated for 30 mins by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of PAK4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 16nM EC50: 4.40nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataKd: 4.5nMAssay Description:Binding affinity to biotin-tagged PAK4 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant PAK4 kinase domain assessed as phosphorylation of FRET peptide substrate at Ser/Thr20 by Zylite assayMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged PAK4 expressed in baculovirus expression system using SGKtide as substrate in...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human recombinant PAK4 kinase domain assessed as phosphorylation of FRET peptide substrate at Ser/Thr20 by Zylite assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PAK4 (unknown origin) using S2 as substrate incubated for 60 mins in the presence of ATP by time-resolved HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PAK4 (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PAK4 (unknown origin) using S2 substrate incubated for 60 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of PAK4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity to biotin-labeled human truncated PAK4 kinase domain by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged PAK4 expressed in baculovirus expression system using SGKtide as substrate in...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
