Report error Found 256 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase tousled-like 2'
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human TLK2 using casein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins by radio...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human TLK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human TLK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TLK2 (unknown origin) in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Inhibition of TLK2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Binding constant for TLK2 kinase domainMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Binding constant for TLK2 kinase domainMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of TLK2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataKd: 64nMAssay Description:Binding affinity to TLK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataKd: 64nMAssay Description:Binding constant for TLK2 kinase domainMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant human TLK2 (388 to end residues) using myelin basic protein as substrate incubated for 2 hrs in presence of ATP by ADP-Glo ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 163nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair











































