Report error Found 5 Enz. Inhib. hit(s) with Target = 'Solute carrier family 12 member 2'
Affinity DataIC50: 240nMAssay Description:Inhibition of NKCC1 in human HT-29 cells assessed as inhibition of rubidium uptake incubated for 20 min by atomic absorption spectroscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of NKCC1 in human HT-29 cells assessed as inhibition of rubidium uptake incubated for 20 min by atomic absorption spectroscopyMore data for this Ligand-Target Pair
Affinity DataKd: 2.84E+3nMAssay Description:Binding affinity to human SLC12A2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at NKKC1 expressed in human HEK293 cells assessed as [86Rb] uptake after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at NKKC1 expressed in human HEK293 cells assessed as [86Rb] uptake after 30 mins by scintillation countingMore data for this Ligand-Target Pair


3D Structure (crystal)

