Report error Found 77 Enz. Inhib. hit(s) with Target = 'Solute carrier family 2, facilitated glucose transporter member 4'
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 47nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 76nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells measured after 15 mins by cell-titer-Glo luminescent cell viability assayMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 650nMAssay Description:Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent methodMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Bayer AG
Curated by ChEMBL
Bayer AG
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair




























3D Structure (crystal)



















