Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with Target = 'Sterol regulatory element-binding protein 1'
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648080(CHEMBL5597982)
Affinity DataEC50:  130nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648082(CHEMBL5590706)
Affinity DataEC50:  190nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648075(CHEMBL5596248)
Affinity DataEC50:  190nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648079(CHEMBL5597153)
Affinity DataEC50:  240nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648078(CHEMBL5596815)
Affinity DataEC50:  310nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648073(CHEMBL5596386)
Affinity DataEC50:  570nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50351538(CHEMBL1824673)
Affinity DataIC50: 700nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50571643(CHEMBL4851466)
Affinity DataIC50: 723nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648081(CHEMBL5598250)
Affinity DataEC50:  770nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50571642(CHEMBL4876668)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50521013(CHEBI:17933 | Calcifediol)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648068(CHEMBL5597394)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648077(CHEMBL5598331)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648065(CHEMBL5597291)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50571644(CHEMBL4851396)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648076(CHEMBL5596939)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648069(CHEMBL5598279)
Affinity DataEC50:  2.80E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648071(CHEMBL5596811)
Affinity DataEC50:  2.90E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648070(CHEMBL5597319)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648075(CHEMBL5596248)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of SREBP1c (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648066(CHEMBL5590383)
Affinity DataEC50:  4.30E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50351521(CHEMBL1824658)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648072(CHEMBL5597943)
Affinity DataEC50:  6.90E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648083(CHEMBL5596907)
Affinity DataEC50:  8.60E+3nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648074(CHEMBL5596592)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648063(CHEMBL5596392)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648064(CHEMBL5597028)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648061(CHEMBL5598324)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648060(CHEMBL5590617)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648062(CHEMBL5597106)
Affinity DataEC50:  3.10E+4nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50648067(CHEMBL5596520)
Affinity DataEC50:  3.80E+4nMAssay Description:Agonist activity at SREBP1c (unknown origin) stably transfected in human HepG2 cells assessed as increase in luciferase activity by counterscreen luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50514121(CHEMBL4442615)
Affinity DataEC50:  0nMAssay Description:Activation of SREBP1c (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSterol regulatory element-binding protein 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50465711(CHEMBL1316881)
Affinity DataEC50:  0nMAssay Description:Activation of SREBP1c (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed