Compile Data Set for Download or QSAR
Report error Found 517 Enz. Inhib. hit(s) with Target = 'Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial'
LigandPNGBDBM50231814(CHEMBL4078870 | US11725000, Compound 289)
Affinity DataEC50:  0.230nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing tBid assessed as reduction in apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50231814(CHEMBL4078870 | US11725000, Compound 289)
Affinity DataEC50:  0.420nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50231783(CHEMBL4078220 | US11725000, Compound 155)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50411095(CHEMBL439507)
Affinity DataIC50: 5nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM613053(US11725000, Compound 316)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613030(US11725000, Compound 292)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613062(US11725000, Compound 325)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613029(US11725000, Compound 291)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613061(US11725000, Compound 324)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613028(US11725000, Compound 290)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613034(US11725000, Compound 296)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613039(US11725000, Compound 301)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613071(US11725000, Compound 334)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613046(US11725000, Compound 309)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613011(US11725000, Compound 273)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613050(US11725000, Compound 313)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613047(US11725000, Compound 310)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612765(US11725000, Compound 27)
Affinity DataEC50:  13nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM50231789(CHEMBL4091379 | US11725000, Compound 127)
Affinity DataEC50:  25nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50411094(CHEMBL379116)
Affinity DataIC50: 26nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50411096(CHEMBL378123)
Affinity DataIC50: 26nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50231785(CHEMBL4064603 | US11725000, Compound 152)
Affinity DataEC50:  27nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50411097(CHEMBL379557)
Affinity DataIC50: 32nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM612761(US11725000, Compound 23)
Affinity DataEC50:  57nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM50231795(CHEMBL4070501 | US11725000, Compound 109)
Affinity DataEC50:  57nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandPNGBDBM612770(US11725000, Compound 32)
Affinity DataEC50:  64nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612759(US11725000, Compound 21)
Affinity DataEC50:  66nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM50231821(CHEMBL4061878 | US11725000, Compound 106)
Affinity DataEC50:  66nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50231820(CHEMBL4092330 | US11725000, Compound 113)
Affinity DataEC50:  69nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandPNGBDBM612763(US11725000, Compound 25)
Affinity DataEC50:  69nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM50231793(CHEMBL4082074 | US11725000, Compound 110)
Affinity DataEC50:  94nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50231825(CHEMBL4090123 | US11725000, Compound 26)
Affinity DataEC50:  94nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613037(US11725000, Compound 299)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613052(US11725000, Compound 315)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613036(US11725000, Compound 298)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613035(US11725000, Compound 297)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613042(US11725000, Compound 304)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613041(US11725000, Compound 303)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613013(US11725000, Compound 275)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613045(US11725000, Compound 308)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613012(US11725000, Compound 274)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613065(US11725000, Compound 328)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM613049(US11725000, Compound 312)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM50231809(CHEMBL4070722 | US11725000, Compound 29)
Affinity DataEC50:  104nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612762(US11725000, Compound 24)
Affinity DataEC50:  110nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM50231794(CHEMBL4071549 | US11725000, Compound 112)
Affinity DataEC50:  110nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50411098(CHEMBL377384)
Affinity DataIC50: 127nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50231817(CHEMBL4086114 | US11725000, Compound 151)
Affinity DataEC50:  164nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50231787(CHEMBL4093871 | US11725000, Compound 143)
Affinity DataEC50:  216nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
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