Compile Data Set for Download or QSAR
Report error Found 449 Enz. Inhib. hit(s) with Target = 'Thioredoxin reductase'
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50633100(CHEMBL5412818)
Affinity DataEC50:  1.31E+4nMAssay Description:Inhibition of TrxR1 in human HeLa cells incubated for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50633100(CHEMBL5412818)
Affinity DataEC50:  3.14E+3nMAssay Description:Inhibition of TrxR1 in human HCT-116 cells incubated for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Mus musculus)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50633100(CHEMBL5412818)
Affinity DataEC50:  2.57E+4nMAssay Description:Inhibition of TrxR1 in mouse CT26 cells incubated for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650948(CHEMBL5633083)
Affinity DataEC50:  1.72E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650949(CHEMBL5632494)
Affinity DataEC50:  1.12E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650950(CHEMBL5631656)
Affinity DataEC50:  1.43E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650951(CHEMBL5633279)
Affinity DataEC50:  1.96E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650952(CHEMBL5633622)
Affinity DataEC50:  1.04E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650953(CHEMBL5633522)
Affinity DataEC50:  1.46E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650954(CHEMBL5633596)
Affinity DataEC50:  1.15E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650955(CHEMBL5631494)
Affinity DataEC50:  1.57E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650956(CHEMBL5632718)
Affinity DataEC50:  1.71E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650957(CHEMBL5631663)
Affinity DataEC50:  8.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650958(CHEMBL5633210)
Affinity DataEC50:  2.35E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650959(CHEMBL5633899)
Affinity DataEC50:  2.85E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650960(CHEMBL5632658)
Affinity DataEC50:  2.66E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650961(CHEMBL5631267)
Affinity DataEC50:  2.36E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650962(CHEMBL5631394)
Affinity DataEC50:  2.14E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650963(CHEMBL5631519)
Affinity DataEC50:  2.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650964(CHEMBL5632820)
Affinity DataEC50:  2.84E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650965(CHEMBL5632215)
Affinity DataEC50:  2.48E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Jianghan University

Curated by ChEMBL
LigandPNGBDBM50650966(CHEMBL5632057)
Affinity DataEC50:  2.45E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  190nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  3.26E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501863(US11028067, Example 4)
Affinity DataIC50: 0.854nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522169(US11161815, Example 25)
Affinity DataIC50: 1.03nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522162(US11161815, Example 18)
Affinity DataIC50: 1.52nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM531217(US11208384, Example 1)
Affinity DataIC50: 3.16nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501865(US11028067, Example 6)
Affinity DataIC50: 3.99nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522165(US11161815, Example 21)
Affinity DataIC50: 4.35nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522166(US11161815, Example 22)
Affinity DataIC50: 5.05nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501860(US11028067, Example 8 | US11028067, Example 1)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522173(US11161815, Example 29)
Affinity DataIC50: 6.78nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501866(US11028067, Example 7)
Affinity DataIC50: 6.90nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522164(US11161815, Example 20)
Affinity DataIC50: 7.16nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522171(US11161815, Example 27)
Affinity DataIC50: 7.33nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522163(US11161815, Example 19)
Affinity DataIC50: 7.60nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501864(US11028067, Example 5)
Affinity DataIC50: 10.8nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522156(US11161815, Example 12)
Affinity DataIC50: 12.3nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576851(CHEMBL1876217)
Affinity DataIC50: 13nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576851(CHEMBL1876217)
Affinity DataIC50: 13nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522167(US11161815, Example 23)
Affinity DataIC50: 14.5nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 18nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 18nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522145(US11161815, Example 1)
Affinity DataIC50: 18.2nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522170(US11161815, Example 26)
Affinity DataIC50: 18.8nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522172(US11161815, Example 28)
Affinity DataIC50: 20.3nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522168(US11161815, Example 24)
Affinity DataIC50: 25.3nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

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