Report error Found 302 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL2'
Affinity DataKd: 0.170nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 0.170nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.170nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 0.690nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human ABL2 using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataKd: 3.40nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.40nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.40nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to human ABL2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant ARG (38 to end residues) using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radio...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity to human active site of N-terminal hexahistidine-tagged ABL2 expressed in Trichoplusia ni infected Sf9 cells by isothermal titration...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of ABL2 (unknown origin) incubated for 120 mins in presence of 33P-ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human ABL2More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to ABL2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 10.1nMAssay Description:Inhibition of human ABL2 using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Arg (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Average Binding Constant for ABL2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human ABL2 using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Inhibition of wild-type human ABL2 (A248 to G542 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 27nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Inhibition of wild-type human ABL2 (A248 to G542 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
