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Report error Found 14 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [866-1054]'
TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM128101(US8796457, 1 | US9505754, 1 | US10206907, Compound...)
Affinity DataIC50: 67nMT: 2°CAssay Description:Recombinant human JAK2 (catalytic domain, amino acids 866-1154; catalog number PV4210) was purchased from Invitrogen. 0.0125 mU of JAK2 was incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM515747(US11053219, Example 200 | US12351572, Example 163)
Affinity DataKd:  550nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756385(US12351572, Example 201)
Affinity DataKd:  550nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756384(US12351572, Example 202)
Affinity DataKd:  550nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756380(US12351572, Example 195)
Affinity DataKd:  5.50E+3nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756377(US12351572, Example 159)
Affinity DataKd:  5.50E+3nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM515745(US11053219, Example 166 | US11731956, Example 166 ...)
Affinity DataKd:  5.50E+3nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM515735(BDBM515746 | US11053219, Example 116 | US11731956,...)
Affinity DataKd:  5.50E+3nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756302(US12351572, Example 38)
Affinity DataKd:  5.50E+3nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM50507816(Bms-986165 | Deucravacitinib | US12351572, Example...)
Affinity DataKd:  5.50E+3nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756381(US12351572, Example 200)
Affinity DataKd:  5.50E+3nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756383(US12351572, Example 199)
Affinity DataKd: >1.00E+4nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756376(US12351572, Example 147)
Affinity DataKd: >1.00E+4nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [866-1054](Human)
Galapagos

US Patent
LigandPNGBDBM756382(US12351572, Example 198)
Affinity DataKd: >1.00E+4nMAssay Description:Similar to the method for TYK2 JH2 binding described above, JAK1 JH2 and JAK2 JH1 domain binding assay was performed using DiscoverX's KINOMEscan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent