SMILES for Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188]

263 SMILES Strings for Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188]

Compound Name

SMILES String

BDBM236248

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F

BDBM236249

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F

BDBM236250

COc1ccc(F)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F

BDBM236254

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F |r|

BDBM236256

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236257

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236279

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C |r|

BDBM236284

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(=O)NOCCO

BDBM236312

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1)C(O)=O |r,wU:30.34,wD:27.30,(4.68,5.6,;3.91,4.26,;4.68,2.93,;6.22,2.93,;6.99,1.6,;6.22,.26,;4.68,.26,;3.91,1.6,;2.37,1.6,;1.46,2.84,;,2.37,;-1.46,2.84,;-2.23,4.18,;-2.37,1.6,;-1.46,.35,;,.83,;1.46,.35,;1.86,-1.14,;.77,-2.22,;3.35,-1.53,;-1.86,-1.14,;-3.35,-1.53,;-3.75,-3.02,;-2.66,-4.11,;-3.06,-5.6,;-1.17,-3.71,;-.77,-2.22,;-3.91,1.6,;-4.68,2.93,;-6.22,2.93,;-6.99,1.6,;-8.53,1.6,;-6.22,.26,;-4.68,.26,;6.99,-1.07,;8.53,-1.07,;6.22,-2.4,)|

BDBM236315

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1 |r,wU:31.35,wD:28.31,(4.68,5.6,;3.91,4.26,;4.68,2.93,;6.22,2.93,;6.99,1.6,;8.53,1.6,;6.22,.26,;4.68,.26,;3.91,1.6,;2.37,1.6,;1.46,2.84,;,2.37,;-1.46,2.84,;-2.23,4.18,;-2.37,1.6,;-1.46,.35,;,.83,;1.46,.35,;1.86,-1.14,;.77,-2.22,;3.35,-1.53,;-1.86,-1.14,;-3.35,-1.53,;-3.75,-3.02,;-2.66,-4.11,;-3.06,-5.6,;-1.17,-3.71,;-.77,-2.22,;-3.91,1.6,;-4.68,2.93,;-6.22,2.93,;-6.99,1.6,;-8.53,1.6,;-6.22,.26,;-4.68,.26,)|

BDBM236325

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CCOCC1

BDBM236348

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)[C@H]1CC[C@H](O)CC1 |r,wU:31.35,wD:28.31,(5.45,5.6,;4.68,4.26,;5.45,2.93,;6.99,2.93,;7.76,1.6,;6.99,.26,;5.45,.26,;4.68,1.6,;3.14,1.6,;2.23,2.84,;.77,2.37,;-.69,2.84,;-1.46,4.18,;-1.6,1.6,;-.69,.35,;.77,.83,;2.23,.35,;2.63,-1.14,;1.54,-2.22,;4.12,-1.53,;-1.09,-1.14,;-0,-2.22,;-.4,-3.71,;-1.89,-4.11,;-2.29,-5.6,;-2.98,-3.02,;-2.58,-1.53,;-3.67,-.45,;-3.14,1.6,;-3.91,2.93,;-5.45,2.93,;-6.22,1.6,;-7.76,1.6,;-5.45,.26,;-3.91,.26,)|

BDBM236349

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)[C@H]1CC[C@H](O)CC1 |r,wU:35.39,wD:32.35,(8.91,-2.4,;8.14,-1.07,;6.6,-1.07,;5.83,-2.4,;5.83,.26,;6.6,1.6,;5.83,2.93,;4.29,2.93,;3.52,4.26,;4.29,5.6,;3.52,1.6,;4.29,.26,;1.98,1.6,;1.08,2.84,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-1.16,-2.22,;-1.56,-3.71,;-3.05,-4.11,;-3.44,-5.6,;-4.13,-3.02,;-3.74,-1.53,;-4.82,-.45,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-5.06,.26,)|

BDBM236350

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2C)[C@H]2CC[C@H](O)CC2)c(OC)n1 |r,wU:29.32,wD:26.28,(8.91,.26,;8.14,1.6,;6.6,1.6,;5.83,.26,;4.29,.26,;3.52,1.6,;1.98,1.6,;1.08,2.84,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-1.16,-2.22,;-1.56,-3.71,;-3.05,-4.11,;-3.44,-5.6,;-4.13,-3.02,;-3.74,-1.53,;-4.82,-.45,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-5.06,.26,;4.29,2.93,;3.52,4.26,;4.29,5.6,;5.83,2.93,)|

BDBM236352

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2C)C2CCOCC2)c(OC)n1

BDBM236354

CNC(=O)N1CCC(CC1)N1C(c2c(cc(-c3cnc(OC)nc3OC)n2C(C)C)C1=O)c1ccc(Cl)cc1

BDBM236355

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CCC(=O)N(C)C1

BDBM236368

COc1ncc(-c2cc3C(=O)N([C@H](c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r|

BDBM236414

COc1nc(ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c[nH]c1=O)N(C)C |r|

BDBM236484

COc1ncc(-c2cc3C(=O)N(C(c3n2C2CC2)c2ccc(Cl)cc2)c2cc(C)c(=O)n(C)c2)c(OC)n1

BDBM236485

COc1ncc(cn1)-c1cc2C(=O)N(C(c2n1C1CC1)c1ccc(Cl)cc1)c1cc(C)c(=O)n(C)c1

BDBM236486

Cc1cc(cn(C)c1=O)N1C(c2c(cc(-c3ccn(C)c(=O)c3)n2C2CC2)C1=O)c1ccc(Cl)cc1

BDBM236251

COc1ccc(CO)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F

BDBM236252

COc1ncccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F

BDBM236253

COc1ccncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F

BDBM236255

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F |r|

BDBM236258

COc1ccc(CO)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236259

COc1ncccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236260

COc1ccncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236261

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)ccc2C)c(OC)n1

BDBM236262

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(=O)N(C)C

BDBM236263

COc1ncncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236264

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C#N

BDBM236265

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C |r|

BDBM236266

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C |r|

BDBM236267

COc1ccc(cc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(=O)N(C)C |r|

BDBM236268

COc1ccc(cc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(=O)N(C)C |r|

BDBM236269

COc1ccc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)ccc2C)c(OC)n1

BDBM236270

COc1ncc(-c2cc3C(=O)N([C@H](c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)ccc2C)c(OC)n1 |r|

BDBM236271

COc1ncc(-c2cc3C(=O)N([C@@H](c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)ccc2C)c(OC)n1 |r|

BDBM236272

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236273

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)ccc2C)c(OC)n1

BDBM236274

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)N(C)C

BDBM236275

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(=O)N1CCOCC1

BDBM236276

CC(C)n1c(cc2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)-c1ccccc1O

BDBM236277

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C

BDBM236278

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C

BDBM236280

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C |r|

BDBM236281

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)-c1nnn[nH]1

BDBM236282

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(O)=O

BDBM236283

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(=O)NCCS(C)(=O)=O

BDBM236285

COc1ccc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)ccc2C)c(OC)c1

BDBM236286

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1ccc(F)c(Cl)c1

BDBM236287

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2ccc(F)c(Cl)c2)c(OC)n1

BDBM236288

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F

BDBM236289

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cccc(Cl)c2F)c(OC)n1

BDBM236290

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)ccc1C

BDBM236291

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)ccc2C)c(OC)n1

BDBM236292

CCn1c(cc2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)-c1cnc(OC)nc1OC

BDBM236293

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1

BDBM236294

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1)C(=O)N1CCOCC1

BDBM236295

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM236296

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1

BDBM236297

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1)C(O)=O

BDBM236298

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1

BDBM236299

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1)N(C)C

BDBM236300

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1ccc(F)c(Cl)c1

BDBM236301

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2ccc(F)c(Cl)c2)c(OC)n1

BDBM236302

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1ccc(F)c(Cl)c1)C(=O)N1CCOCC1

BDBM236303

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1ccc(F)c(Cl)c1)C(O)=O

BDBM236305

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1ccc(F)c(Cl)c1)N(C)C

BDBM236306

COc1ccccc1-c1c(C#N)c2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C |(4.68,5.49,;3.91,4.15,;4.68,2.82,;6.22,2.82,;6.99,1.49,;6.22,.15,;4.68,.15,;3.91,1.49,;2.37,1.49,;1.46,2.73,;1.86,4.22,;2.26,5.71,;,2.26,;-1.46,2.73,;-2.23,4.07,;-2.37,1.49,;-1.46,.24,;,.72,;1.46,.24,;1.86,-1.25,;.77,-2.33,;3.35,-1.64,;-1.86,-1.25,;-3.35,-1.64,;-3.75,-3.13,;-2.66,-4.22,;-3.06,-5.71,;-1.17,-3.82,;-.77,-2.33,;-3.91,1.49,;-4.68,.15,;-6.22,.15,;-6.99,-1.18,;-6.99,1.49,;-6.22,2.82,;-4.68,2.82,;-3.91,4.15,)|

BDBM236307

COc1ccc(CC(O)=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236308

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(N)=O

BDBM236309

CNS(=O)(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236310

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1 |r,wU:30.34,wD:27.30,(5.45,5.6,;4.68,4.26,;5.45,2.93,;6.99,2.93,;7.76,1.6,;6.99,.26,;5.45,.26,;4.68,1.6,;3.14,1.6,;2.23,2.84,;.77,2.37,;-.69,2.84,;-1.46,4.18,;-1.6,1.6,;-.69,.35,;.77,.83,;2.23,.35,;2.63,-1.14,;1.54,-2.22,;4.12,-1.53,;-1.09,-1.14,;-2.58,-1.53,;-2.98,-3.02,;-1.89,-4.11,;-2.29,-5.6,;-.4,-3.71,;-0,-2.22,;-3.14,1.6,;-3.91,2.93,;-5.45,2.93,;-6.22,1.6,;-7.76,1.6,;-5.45,.26,;-3.91,.26,)|

BDBM236311

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1 |r,wU:34.38,wD:31.34,(8.91,-2.4,;8.14,-1.07,;6.6,-1.07,;5.83,-2.4,;5.83,.26,;6.6,1.6,;5.83,2.93,;4.29,2.93,;3.52,4.26,;4.29,5.6,;3.52,1.6,;4.29,.26,;1.98,1.6,;1.08,2.84,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-3.74,-1.53,;-4.13,-3.02,;-3.05,-4.11,;-3.44,-5.6,;-1.56,-3.71,;-1.16,-2.22,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-5.06,.26,)|

BDBM236313

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)[C@H]2CC[C@H](O)CC2)c(OC)n1 |r,wU:28.31,wD:25.27,(8.91,.26,;8.14,1.6,;6.6,1.6,;5.83,.26,;4.29,.26,;3.52,1.6,;1.98,1.6,;1.08,2.84,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-3.74,-1.53,;-4.13,-3.02,;-3.05,-4.11,;-3.44,-5.6,;-1.56,-3.71,;-1.16,-2.22,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-5.06,.26,;4.29,2.93,;3.52,4.26,;4.29,5.6,;5.83,2.93,)|

BDBM236314

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1)C#N |r,wU:30.34,wD:27.30,(5.06,5.6,;4.29,4.26,;5.06,2.93,;6.6,2.93,;7.37,1.6,;6.6,.26,;5.06,.26,;4.29,1.6,;2.75,1.6,;1.85,2.84,;.39,2.37,;-1.08,2.84,;-1.85,4.18,;-1.98,1.6,;-1.08,.35,;.39,.83,;1.85,.35,;2.25,-1.14,;1.16,-2.22,;3.74,-1.53,;-1.48,-1.14,;-2.97,-1.53,;-3.36,-3.02,;-2.28,-4.11,;-2.67,-5.6,;-.79,-3.71,;-.39,-2.22,;-3.52,1.6,;-4.29,2.93,;-5.83,2.93,;-6.6,1.6,;-8.14,1.6,;-5.83,.26,;-4.29,.26,;7.37,-1.07,;8.14,-2.4,)|

BDBM236316

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1)N(C)C |r,wU:30.34,wD:27.30,(4.29,5.6,;3.52,4.26,;4.29,2.93,;5.83,2.93,;6.6,1.6,;5.83,.26,;4.29,.26,;3.52,1.6,;1.98,1.6,;1.08,2.84,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-3.74,-1.53,;-4.13,-3.02,;-3.05,-4.11,;-3.44,-5.6,;-1.56,-3.71,;-1.16,-2.22,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-5.06,.26,;8.14,1.6,;8.91,.26,;8.91,2.93,)|

BDBM236317

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM236318

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)cn(C)c1=O

BDBM236319

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM236320

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)cn(C)c1=O)N(C)C

BDBM236321

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CCOCC1

BDBM236322

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CCOCC1

BDBM236323

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)C2CCOCC2)c(OC)n1

BDBM236324

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CCOCC1)C#N

BDBM236326

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CCOCC1)N(C)C

BDBM236327

COc1ccc(CC(N)=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236328

CNC(=O)Cc1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236329

COc1ccc(CC(=O)N(C)C)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236330

CCOC(=O)Cc1cnc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F

BDBM236331

COc1cnc(CC(O)=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F

BDBM236332

CNC(=O)Cc1cnc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F

BDBM236333

CNC(=O)Cc1cc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cccc(Cl)c2F)c(OC)cn1

BDBM236334

COc1cnc(CC#N)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F

BDBM236335

COc1ncc(CC#N)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F

BDBM236336

COc1ccc(cc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(O)=O |r|

BDBM236337

COc1ccc(cc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(O)=O |r|

BDBM236338

COc1ccc(CC(O)=O)cc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C |r|

BDBM236339

COc1ccc(CC(O)=O)cc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C |r|

BDBM236340

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1ccc(F)c(Cl)c1)N(C)C

BDBM236341

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F)N(C)C

BDBM236342

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)ccc1C)N(C)C

BDBM236343

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C#N

BDBM236344

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C#N

BDBM236345

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)ccc2C#N)c(OC)n1

BDBM236346

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C#N

BDBM236347

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C#N)N(C)C

BDBM236351

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)C1CCOCC1

BDBM236353

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)C2CCNCC2)c(OC)n1

BDBM236356

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)C2CCC(=O)N(C)C2)c(OC)n1

BDBM236357

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)C2CN(C)C(=O)N(C)C2)c(OC)n1

BDBM236358

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cn(C)c(=O)cc2C)c(OC)n1

BDBM236359

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cn(C)c(=O)cc1C)N(C)C

BDBM236360

COc1cccnc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236361

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)S(C)(=O)=O

BDBM236362

COc1ccccc1-c1c(F)c2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C |(4.68,5.6,;3.91,4.26,;4.68,2.93,;6.22,2.93,;6.99,1.6,;6.22,.26,;4.68,.26,;3.91,1.6,;2.37,1.6,;1.46,2.84,;2.23,4.18,;,2.37,;-1.46,2.84,;-2.23,4.18,;-2.37,1.6,;-1.46,.35,;,.83,;1.46,.35,;1.86,-1.14,;.77,-2.22,;3.35,-1.53,;-1.86,-1.14,;-3.35,-1.53,;-3.75,-3.02,;-2.66,-4.11,;-3.06,-5.6,;-1.17,-3.71,;-.77,-2.22,;-3.91,1.6,;-4.68,.26,;-6.22,.26,;-6.99,-1.07,;-6.99,1.6,;-6.22,2.93,;-4.68,2.93,;-3.91,4.26,)|

BDBM236363

COc1ccccc1-c1cc2C(=O)N(c3cc(Cl)ccc3C)C(C)(c2n1C(C)C)c1ccc(Cl)cc1

BDBM236364

COc1ncc(-c2cc3C(=O)N(c4cc(Cl)c(=O)n(C)c4)C(C)(c3n2C(C)C)c2ccc(Cl)cc2)c(OC)n1

BDBM236365

COc1ccc(CC(O)=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1

BDBM236366

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1)S(C)(=O)=O

BDBM236367

COc1ncc(-c2c(C#N)c3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |(8.91,.26,;8.14,1.6,;6.6,1.6,;5.83,.26,;4.29,.26,;3.52,1.6,;1.98,1.6,;1.08,2.84,;1.85,4.18,;2.62,5.51,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-3.74,-1.53,;-4.13,-3.02,;-3.05,-4.11,;-3.44,-5.6,;-1.56,-3.71,;-1.16,-2.22,;-4.29,1.6,;-5.06,.26,;-6.6,.26,;-7.37,-1.07,;-7.37,1.6,;-8.91,1.6,;-6.6,2.93,;-7.37,4.26,;-5.06,2.93,;4.29,2.93,;3.52,4.26,;4.29,5.6,;5.83,2.93,)|

BDBM236369

COc1ncc(-c2cc3C(=O)N([C@@H](c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r|

BDBM236370

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c[nH]c1=O)N(C)C

BDBM236371

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c[nH]c2=O)c(OC)n1

BDBM236372

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c[nH]c1=O

BDBM236373

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)c[nH]c2=O)c(OC)n1

BDBM236374

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c[nH]c1=O)N(C)C

BDBM236375

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)c[nH]c2=O)c(OC)n1

BDBM236376

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)cn(C)c1=O

BDBM236377

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM236378

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)cn(C)c1=O)N(C)C

BDBM236379

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM236380

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM236381

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1c[nH]c(=O)c(Cl)c1

BDBM236382

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2c[nH]c(=O)c(Cl)c2)c(OC)n1

BDBM236383

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1c[nH]c(=O)c(Cl)c1)N(C)C

BDBM236384

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2c[nH]c(=O)c(Cl)c2)c(OC)n1

BDBM236385

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1c[nH]c(=O)c(Cl)c1

BDBM236386

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2c[nH]c(=O)c(Cl)c2)c(OC)n1

BDBM236387

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1c[nH]c(=O)c(Cl)c1)N(C)C

BDBM236388

CO[C@H]1CC[C@@H](CC1)N1C(c2c(cc(-c3cnc(N)nc3OC)n2C(C)C)C1=O)c1ccc(Cl)cc1 |r,wU:2.1,wD:5.8,(-8.91,2.93,;-8.14,1.6,;-6.6,1.6,;-5.83,2.93,;-4.29,2.93,;-3.52,1.6,;-4.29,.26,;-5.83,.26,;-1.98,1.6,;-1.08,.35,;.38,.83,;.38,2.37,;1.85,2.84,;2.75,1.6,;4.29,1.6,;5.06,.26,;6.6,.26,;7.37,1.6,;8.91,1.6,;6.6,2.93,;5.06,2.93,;4.29,4.26,;5.06,5.6,;1.85,.35,;2.25,-1.14,;3.74,-1.53,;1.16,-2.22,;-1.08,2.84,;-1.85,4.18,;-1.48,-1.14,;-2.97,-1.53,;-3.36,-3.02,;-2.28,-4.11,;-2.67,-5.6,;-.79,-3.71,;-.39,-2.22,)|

BDBM236389

CO[C@H]1CC[C@@H](CC1)N1C(c2c(cc(-c3cnc(nc3OC)N(C)C)n2C(C)C)C1=O)c1ccc(Cl)cc1 |r,wU:2.1,wD:5.8,(-9.3,2.93,;-8.53,1.6,;-6.99,1.6,;-6.22,2.93,;-4.68,2.93,;-3.91,1.6,;-4.68,.26,;-6.22,.26,;-2.37,1.6,;-1.46,.35,;,.83,;,2.37,;1.46,2.84,;2.37,1.6,;3.91,1.6,;4.68,.26,;6.22,.26,;6.99,1.6,;6.22,2.93,;4.68,2.93,;3.91,4.26,;4.68,5.6,;8.53,1.6,;9.3,2.93,;9.3,.26,;1.46,.35,;1.86,-1.14,;3.35,-1.53,;.77,-2.22,;-1.46,2.84,;-2.23,4.18,;-1.86,-1.14,;-3.35,-1.53,;-3.75,-3.02,;-2.66,-4.11,;-3.06,-5.6,;-1.17,-3.71,;-.77,-2.22,)|

BDBM236390

CO[C@H]1CC[C@@H](CC1)N1C(c2c(cc(-c3cnc(OC)nc3OC)n2C(C)C)C1=O)c1ccc(Cl)cc1 |r,wU:2.1,wD:5.8,(-9.3,2.93,;-8.53,1.6,;-6.99,1.6,;-6.22,2.93,;-4.68,2.93,;-3.91,1.6,;-4.68,.26,;-6.22,.26,;-2.37,1.6,;-1.46,.35,;,.83,;,2.37,;1.46,2.84,;2.37,1.6,;3.91,1.6,;4.68,.26,;6.22,.26,;6.99,1.6,;8.53,1.6,;9.3,2.93,;6.22,2.93,;4.68,2.93,;3.91,4.26,;4.68,5.6,;1.46,.35,;1.86,-1.14,;3.35,-1.53,;.77,-2.22,;-1.46,2.84,;-2.23,4.18,;-1.86,-1.14,;-3.35,-1.53,;-3.75,-3.02,;-2.66,-4.11,;-3.06,-5.6,;-1.17,-3.71,;-.77,-2.22,)|

BDBM236391

COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)c(=O)n(C)c1

BDBM236392

CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)c(=O)n(C)c1

BDBM236393

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2C)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM236394

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)c(=O)n(C)c1)N(C)C

BDBM236395

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)c(=O)n(C)c1

BDBM236396

COc1cn(C)c(=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C

BDBM236397

COc1cn(C)c(=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1

BDBM236398

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2C)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM236399

CNc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2c[nH]c(=O)c(Cl)c2)c(OC)n1

BDBM236400

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM236401

COc1nc(N)ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F |r|

BDBM236402

COc1nc(N)ncc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F |r|

BDBM236403

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c(=O)n(C)c2F)c(OC)n1

BDBM236404

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)C2CCOCC2)c(OC)n1

BDBM236405

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)C1CCOCC1)N(C)C

BDBM236406

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CN(C)C(=O)N(C)C1)N(C)C

BDBM236407

COc1ncc(-c2cc3C(=O)N([C@H](c3n2C(C)C)c2ccc(Cl)cc2C)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r|

BDBM236408

COc1ncc(-c2cc3C(=O)N([C@@H](c3n2C(C)C)c2ccc(Cl)cc2C)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r|

BDBM236409

COc1ncc(-c2cc3C(=O)N(c4cc(Cl)c(=O)n(C)c4)[C@](C)(c3n2C(C)C)c2ccc(Cl)cc2)c(OC)n1 |r|

BDBM236410

COc1ncc(-c2cc3C(=O)N(c4cc(Cl)c(=O)n(C)c4)[C@@](C)(c3n2C(C)C)c2ccc(Cl)cc2)c(OC)n1 |r|

BDBM236411

COc1nc(ncc1-c1c(C#N)c2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1)N(C)C |(4.29,5.6,;3.52,4.26,;4.29,2.93,;5.83,2.93,;6.6,1.6,;5.83,.26,;4.29,.26,;3.52,1.6,;1.98,1.6,;1.08,2.84,;1.85,4.18,;2.62,5.51,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;2.97,-1.53,;.39,-2.22,;-2.25,-1.14,;-3.74,-1.53,;-4.13,-3.02,;-3.05,-4.11,;-3.44,-5.6,;-1.56,-3.71,;-1.16,-2.22,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,4.26,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-7.37,-1.07,;-5.06,.26,;8.14,1.6,;8.91,.26,;8.91,2.93,)|

BDBM236412

CNc1ncc(-c2cc3C(=O)N([C@H](c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)cn(C)c2=O)c(OC)n1 |r|

BDBM236413

CNc1ncc(-c2cc3C(=O)N([C@@H](c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)cn(C)c2=O)c(OC)n1 |r|

BDBM236415

COc1nc(ncc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c[nH]c1=O)N(C)C |r|

BDBM236416

COc1nc(ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(cc1)C#N)c1ccc(F)c(Cl)c1)N(C)C |r|

BDBM236417

COc1nc(ncc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(cc1)C#N)c1ccc(F)c(Cl)c1)N(C)C |r|

BDBM236418

COc1nc(N)ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(cc1)C#N)c1ccc(F)c(Cl)c1 |r|

BDBM236419

COc1nc(N)ncc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(cc1)C#N)c1ccc(F)c(Cl)c1 |r|

BDBM236420

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)[C@H]2CC[C@H](O)CC2)c(OC)n1 |r,wU:29.32,wD:26.28,(8.91,1.01,;8.14,2.34,;6.6,2.34,;5.83,1.01,;4.29,1.01,;3.52,2.34,;1.98,2.34,;1.08,3.59,;-.38,3.11,;-1.85,3.59,;-2.62,4.92,;-2.75,2.34,;-1.85,1.1,;-.38,1.57,;1.08,1.1,;1.48,-.39,;.39,-1.48,;2.97,-.79,;-2.25,-.39,;-3.74,-.79,;-4.13,-2.28,;-3.05,-3.37,;-1.56,-2.97,;-1.16,-1.48,;-3.44,-4.85,;-3.84,-6.34,;-4.29,2.34,;-5.06,3.67,;-6.6,3.67,;-7.37,2.34,;-8.91,2.34,;-6.6,1.01,;-5.06,1.01,;4.29,3.67,;3.52,5.01,;4.29,6.34,;5.83,3.67,)|

BDBM236421

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)[C@H]1CC[C@H](O)CC1)N(C)C |r,wU:31.35,wD:28.31,(4.29,6.34,;3.52,5.01,;4.29,3.67,;5.83,3.67,;6.6,2.34,;5.83,1.01,;4.29,1.01,;3.52,2.34,;1.98,2.34,;1.08,3.59,;-.38,3.11,;-1.85,3.59,;-2.62,4.92,;-2.75,2.34,;-1.85,1.1,;-.38,1.57,;1.08,1.1,;1.48,-.39,;.39,-1.48,;2.97,-.79,;-2.25,-.39,;-3.74,-.79,;-4.13,-2.28,;-3.05,-3.37,;-1.56,-2.97,;-1.16,-1.48,;-3.44,-4.85,;-3.84,-6.34,;-4.29,2.34,;-5.06,3.67,;-6.6,3.67,;-7.37,2.34,;-8.91,2.34,;-6.6,1.01,;-5.06,1.01,;8.14,2.34,;8.91,1.01,;8.91,3.67,)|

BDBM236422

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(C)nn1C

BDBM236423

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(C)nn2C)c(OC)n1

BDBM236424

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(C)nn1C)N(C)C

BDBM236425

COc1cn(C)c(=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(C)nn1C

BDBM236426

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2cc(C)nn2C)c(OC)n1

BDBM236427

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(C)nn1C)N(C)C

BDBM236428

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cn(C)nc2C)c(OC)n1

BDBM236429

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cn(C)nc1C)N(C)C

BDBM236430

COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cn(C)nc1C)S(C)(=O)=O

BDBM236431

COc1cn(C)c(=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cn(C)nc1C

BDBM236432

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c(=O)n(C)c1)N(C)C

BDBM236433

COc1ncc(-c2cc3C(=O)N([C@H](c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r|

BDBM236434

COc1ncc(-c2cc3C(=O)N([C@@H](c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r|

BDBM236435

COc1nc(ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1)c1c[nH]c(=O)c(Cl)c1)N(C)C |r|

BDBM236436

COc1nc(ncc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(Cl)cc1)c1c[nH]c(=O)c(Cl)c1)N(C)C |r|

BDBM236437

COc1nc(ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(cc1)C#N)C1CCOCC1)N(C)C |r|

BDBM236438

COc1nc(ncc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(cc1)C#N)C1CCOCC1)N(C)C |r|

BDBM236439

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)c(F)c2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM236440

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)c(F)c1)c1cc(Cl)c(=O)n(C)c1)N(C)C

BDBM236441

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(C#N)c(F)c1)c1cc(Cl)c(=O)n(C)c1)N(C)C

BDBM236442

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(C#N)c(F)c2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM236443

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)c(F)c2)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM236444

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)c(F)c1)c1cc(Cl)cn(C)c1=O)N(C)C

BDBM236445

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(C#N)c(F)c2)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM236446

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(C#N)c(F)c1)c1cc(Cl)cn(C)c1=O)N(C)C

BDBM236447

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(C#N)c(F)c2)c2cc(Cl)c[nH]c2=O)c(OC)n1

BDBM236448

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(C#N)c(F)c1)c1cc(Cl)c[nH]c1=O)N(C)C

BDBM236449

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)c(F)c2)c2cc(Cl)c[nH]c2=O)c(OC)n1

BDBM236450

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)c(F)c1)c1cc(Cl)c[nH]c1=O)N(C)C

BDBM236451

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c[nH]c2=O)c(OC)n1

BDBM236452

COc1cn(C)c(=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)cnc1OC

BDBM236453

COc1ncc(Cl)cc1N1C(c2c(cc(-c3cnc(N)nc3OC)n2C(C)C)C1=O)c1ccc(Cl)cc1

BDBM236454

COc1ncc(Cl)cc1N1C(c2c(cc(-c3cnc(nc3OC)N(C)C)n2C(C)C)C1=O)c1ccc(cc1)C#N

BDBM236455

COc1cn(C)c(=O)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1c(F)c(C)nn1C

BDBM236456

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1c(F)c(C)nn1C)N(C)C

BDBM236457

COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1c(F)c(C)nn1C

BDBM236458

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(cc2)C#N)c2c(F)c(C)nn2C)c(OC)n1

BDBM236459

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1F)c1cc(C)nn1C)N(C)C

BDBM236460

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cn2)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM236461

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cn2)c2ccc(F)c(Cl)c2)c(OC)n1

BDBM236462

COc1ncc(-c2cc3C(=O)N([C@H](c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)cn(C)c2=O)c(OC)n1 |r|

BDBM236463

COc1ncc(-c2cc3C(=O)N([C@@H](c3n2C(C)C)c2ccc(cc2)C#N)c2cc(Cl)cn(C)c2=O)c(OC)n1 |r|

BDBM236464

CCOC(=O)c1c2C(=O)N(C(c2n(C(C)C)c1-c1cnc(OC)nc1OC)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1 |(3.26,6.8,;2.17,5.71,;2.57,4.22,;1.48,3.13,;.39,4.22,;1.08,1.64,;-.38,1.17,;-1.85,1.64,;-2.62,2.98,;-2.75,.4,;-1.85,-.85,;-.38,-.37,;1.08,-.85,;1.48,-2.33,;.39,-3.42,;2.97,-2.73,;1.98,.4,;3.52,.4,;4.29,-.94,;5.83,-.94,;6.6,.4,;8.14,.4,;8.91,-.94,;5.83,1.73,;4.29,1.73,;3.52,3.07,;4.29,4.4,;-2.25,-2.33,;-3.74,-2.73,;-4.13,-4.22,;-3.05,-5.31,;-3.44,-6.8,;-1.56,-4.91,;-1.16,-3.42,;-4.29,.4,;-5.06,1.73,;-6.6,1.73,;-7.37,3.07,;-7.37,.4,;-8.91,.4,;-6.6,-.94,;-7.37,-2.27,;-5.06,-.94,)|

BDBM236465

COc1ncc(-c2c(C(O)=O)c3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |(8.91,.26,;8.14,1.6,;6.6,1.6,;5.83,.26,;4.29,.26,;3.52,1.6,;1.98,1.6,;1.08,2.84,;1.48,4.33,;2.57,5.42,;.39,5.42,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-3.74,-1.53,;-4.13,-3.02,;-3.05,-4.11,;-3.44,-5.6,;-1.56,-3.71,;-1.16,-2.22,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,4.26,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-7.37,-1.07,;-5.06,.26,;4.29,2.93,;3.52,4.26,;4.29,5.6,;5.83,2.93,)|

BDBM236466

COC[C@@H](C)n1c(cc2C(=O)N(C(c12)c1ccc(cc1)C#N)c1ccc(F)c(Cl)c1)-c1cnc(OC)nc1OC |r|

BDBM236467

COC[C@@H](C)n1c(cc2C(=O)N(C(c12)c1ccc(cc1)C#N)c1ccc(F)c(Cl)c1)-c1cnc(N)nc1OC |r|

BDBM236468

COC[C@@H](C)n1c(cc2C(=O)N(C(c12)c1ccc(Cl)cc1)c1ccc(F)c(Cl)c1)-c1cnc(N)nc1OC |r|

BDBM236469

COC[C@@H](C)n1c(cc2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1)-c1cnc(OC)nc1OC |r|

BDBM236470

COc1nc(ncc1-c1c(C(O)=O)c2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1)N(C)C |(4.29,5.54,;3.52,4.21,;4.29,2.87,;5.83,2.87,;6.6,1.54,;5.83,.2,;4.29,.2,;3.52,1.54,;1.98,1.54,;1.08,2.78,;1.08,4.32,;1.85,5.66,;-.46,4.32,;-.39,2.31,;-1.85,2.78,;-2.62,4.12,;-2.75,1.54,;-1.85,.29,;-.39,.77,;1.08,.29,;1.48,-1.2,;.39,-2.28,;2.97,-1.59,;-2.25,-1.2,;-3.74,-1.59,;-4.13,-3.08,;-3.05,-4.17,;-3.44,-5.66,;-1.56,-3.77,;-1.16,-2.28,;-4.29,1.54,;-5.06,.2,;-6.6,.2,;-7.37,-1.13,;-7.37,1.54,;-8.91,1.54,;-6.6,2.87,;-7.37,4.21,;-5.06,2.87,;8.14,1.54,;8.91,2.87,;8.91,.2,)|

BDBM236471

COc1nc(ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)c(F)c1)c1cc(Cl)c[nH]c1=O)N(C)C |r|

BDBM236472

COc1nc(ncc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(Cl)c(F)c1)c1cc(Cl)c[nH]c1=O)N(C)C |r|

BDBM236473

COC[C@@H](C)n1c(cc2C(=O)N([C@H](c12)c1ccc(Cl)cc1)c1ccc(F)c(Cl)c1)-c1cnc(N)nc1OC |r|

BDBM236474

COC[C@@H](C)n1c(cc2C(=O)N([C@@H](c12)c1ccc(Cl)cc1)c1ccc(F)c(Cl)c1)-c1cnc(N)nc1OC |r|

BDBM236475

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1c(F)c(C)nn1C)N(C)C

BDBM236476

COc1nc(ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c(=O)n(C)c1)N(C)C |r|

BDBM236477

COc1nc(ncc1-c1cc2C(=O)N([C@@H](c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c(=O)n(C)c1)N(C)C |r|

BDBM236478

COc1nc(ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cn1)c1cccc(Cl)c1F)N(C)C

BDBM236479

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cn2)c2cc(Cl)ccc2C)c(OC)n1

BDBM236480

COc1ncncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c(=O)n(C)c1

BDBM236481

COc1ncc(-c2cc3C(=O)N([C@H](c3n2C(C)C)c2ccc(C#N)c(F)c2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r|

BDBM236482

COc1ncc(-c2cc3C(=O)N([C@@H](c3n2C(C)C)c2ccc(C#N)c(F)c2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r|

BDBM236483

COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(C)cn(C)c2=O)c(OC)n1

BDBM238899

COc1ccccc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cccc(Cl)c1F

BDBM238900

COc1ccccc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F

BDBM238901

COc1ccccc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C

BDBM238902

COc1ccncc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C

BDBM238903

CC(C)N1C2C(N(C(=O)N=C2N=C1Br)c1cccc(Cl)c1F)c1ccc(Cl)cc1 |c:9,12|

BDBM238904

COc1ccncc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cccc(Cl)c1F

BDBM238905

COc1ccc(F)cc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C

BDBM238906

COc1ccc(cc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C)C(=O)NCCO

BDBM238907

CNC(=O)c1ccc(OC)c(c1)-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C

BDBM238908

COc1ccc(cc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C)C(=O)N(C)C

BDBM238909

COc1ccc(CO)cc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C

BDBM238910

COc1ccc(cc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C)C#N

BDBM238911

COc1ccccc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)ccc1C

BDBM238912

COc1ccccc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(cc1)C#N)c1cccc(Cl)c1F

BDBM238913

COc1ncc(-c2nc3NC(=O)N(C(c3n2C(C)C)c2ccc(Cl)c(F)c2)c2ccc(F)c(Cl)c2)c(OC)n1

BDBM238914

COc1ncc(-c2nc3NC(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2C)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM238915

COc1ncc(-c2nc3NC(=O)N(C(c3n2C(C)C)c2ccc(Cl)c(F)c2)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM238916

COc1ncc(-c2nc3NC(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)cn(C)c2=O)c(OC)n1

BDBM238917

COc1ncc(-c2nc3NC(=O)N(C(c3n2C(C)C)c2ccc(Cl)c(F)c2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1

BDBM238918

COc1nc(ncc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)c(F)c1)c1cc(Cl)c[nH]c1=O)N(C)C

BDBM238919

COc1nc(N)ncc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)cn(C)c1=O

BDBM238920

COc1nc(ncc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)cn(C)c1=O)N(C)C

BDBM238921

COc1nc(ncc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)c(F)c1)c1ccc(F)c(Cl)c1)N(C)C

BDBM238922

COc1nc(ncc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)c(F)c1)c1cc(Cl)cn(C)c1=O)N(C)C

BDBM238923

COc1ncc(-c2nc3NC(=O)N(C(c3n2C(C)C)c2ccc(Cl)c(F)c2)c2cc(Cl)c[nH]c2=O)c(OC)n1