50 SMILES Strings for Non-receptor tyrosine-protein kinase TYK2 [871-1187]

Compound Name
SMILES String
CC1(C)CN(C1)C(=O)c1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
CN1CCN(CC1)c1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
O=C(Nc1nc2cccc(-c3ccc(cc3)S(=O)(=O)NC3CC3)n2n1)C1CC1
Fc1cc(ccc1OCc1ccccc1)-c1cccc2nc(NC(=O)C3CC3)nn12
O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)N3CCCCC3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(CN4CCOCC4)cc3)n2n1)C1CC1
Fc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
O=C(Nc1nc2cccc(-c3ccc(OCc4cccnc4)cc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(OCc4ccccn4)cc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(OCC4CCC4)cc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(OC4CCCC4)cc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(OCC4CCCCC4)cc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)NCc3cccnc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)Nc3ccccc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(Oc4ccccc4)cc3)n2n1)C1CC1
Cn1ccc(COc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)n1
Cc1noc(C)c1COc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
Cc1cc(COc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)n(C)n1
Cc1n[nH]c(C)c1CCOc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
Cc1cc(COc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)no1
Fc1ccccc1S(=O)(=O)Nc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)NCc3ccccc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(OCc4ccccc4)nc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)N3CCc4ccccc4C3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(NS(=O)(=O)C4CC4)cc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)NCCOc3ccccc3)n2n1)C1CC1
Cc1cc(COc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)nn1C
O=C(Nc1nc2cccc(-c3ccc(cc3)-c3cccnc3)n2n1)C1CC1
O=C(CCc1ccccc1)Nc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
Fc1cc(ccc1-c1cccc2nc(NC(=O)C3CC3)nn12)C(=O)NCCc1ccccc1
Fc1cccc(NC(=O)COc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)c1
O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)N[C@H]3CCN(Cc4ccccc4)C3)n2n1)C1CC1 |r|
O=C(Nc1nc2cccc(-c3ccc4n(Cc5ccccc5)ccc4c3)n2n1)C1CC1
OC1(Cc2ccccc2)CCN(CC1)C(=O)c1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
O=C(Nc1nc2cccc(-c3ccc(OCc4ccccc4)cc3)n2n1)C1CC1
O=C(Nc1nc2cccc(-c3ccc(OCc4ccc(nc4)C#N)cc3)n2n1)C1CC1
FC1(F)CCN(C1)C(=O)c1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
O=C(Nc1nc2cccc(-c3ccc(CNc4ccon4)cc3)n2n1)C1CC1
NC(=O)c1ccccc1NCc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
FC1(F)CN(C1)C(=O)Cc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
FC(F)(F)C1CCN(CC1)C(=O)Cc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
CNc1cc2n([C@H]3CC[C@H](CC#N)CC3)c(nc2cn1)C(C)O |r,wU:6.5,wD:9.9,(-2.58,-3.7,;-1.24,-4.47,;.09,-3.7,;.09,-2.16,;1.42,-1.39,;1.74,.12,;.66,1.2,;-.83,.81,;-1.92,1.89,;-1.52,3.38,;-2.61,4.47,;-4.1,4.07,;-5.59,3.67,;-.03,3.78,;1.05,2.69,;3.28,.28,;3.9,-1.13,;2.76,-2.16,;2.76,-3.7,;1.42,-4.47,;4.05,1.61,;3.28,2.94,;5.59,1.61,)|
CNc1cc2n([C@H]3CC[C@H](CC#N)CC3)c(nc2cn1)[C@@H](C)O |r,wU:6.5,20.24,wD:9.9,(1.71,-18.63,;3.03,-19.4,;4.36,-18.63,;4.36,-17.09,;5.69,-16.32,;6.01,-14.81,;4.98,-13.67,;3.48,-13.99,;2.45,-12.84,;2.92,-11.38,;1.89,-10.23,;.38,-10.55,;-1.12,-10.87,;4.43,-11.06,;5.46,-12.2,;7.54,-14.65,;8.17,-16.06,;7.03,-17.09,;7.03,-18.63,;5.69,-19.4,;8.31,-13.32,;7.54,-11.98,;9.85,-13.32,)|
CNc1cc2n([C@H]3CC[C@H](CC#N)CC3)c(nc2cn1)[C@@H](C)O |r,wU:6.5,20.24,wD:9.9,(-2.58,-3.7,;-1.24,-4.47,;.09,-3.7,;.09,-2.16,;1.42,-1.39,;1.74,.12,;.66,1.2,;-.83,.81,;-1.92,1.89,;-1.52,3.38,;-2.61,4.47,;-4.1,4.07,;-5.59,3.67,;-.03,3.78,;1.05,2.69,;3.28,.28,;3.9,-1.13,;2.76,-2.16,;2.76,-3.7,;1.42,-4.47,;4.05,1.61,;3.28,2.94,;5.59,1.61,)|
CNc1cc2n([C@@H]3CC[C@H](CC#N)CC3)c(nc2cn1)C(C)O |r,wU:6.5,9.9,(-2.58,-3.7,;-1.24,-4.47,;.09,-3.7,;.09,-2.16,;1.42,-1.39,;1.74,.12,;.66,1.2,;1.05,2.69,;-.03,3.78,;-1.52,3.38,;-2.61,4.47,;-4.1,4.07,;-5.59,3.67,;-1.92,1.89,;-.83,.81,;3.28,.28,;3.9,-1.13,;2.76,-2.16,;2.76,-3.7,;1.42,-4.47,;4.05,1.61,;3.28,2.94,;5.59,1.61,)|
CNc1cc2n([C@@H]3CC[C@H](CC#N)CC3)c(nc2cn1)[C@@H](C)O |r,wU:20.24,6.5,9.9,(-2.67,-3.81,;-1.34,-4.58,;-.01,-3.81,;-.01,-2.27,;1.33,-1.5,;1.65,0,;.62,1.15,;1.09,2.61,;.06,3.76,;-1.44,3.44,;-2.48,4.58,;-3.98,4.26,;-5.49,3.94,;-1.92,1.97,;-.89,.83,;3.18,.17,;3.8,-1.24,;2.66,-2.27,;2.66,-3.81,;1.33,-4.58,;3.95,1.5,;3.18,2.83,;5.49,1.5,)|
C[C@H](c1nc2cnc3c(c2n1C4CCC(CC4)CC#N)cc[nH]3)O
C[C@H](O)c1nc2cnc3[nH]ccc3c2n1[C@H]1CC[C@H](CC#N)CC1 |r,wU:1.1,18.21,wD:15.17,(-3.7,2.11,;-4.17,.65,;-5.68,.33,;-3.14,-.5,;-3.46,-2.01,;-2.13,-2.78,;-1.81,-4.28,;-.34,-4.76,;.8,-3.73,;2.33,-3.89,;2.96,-2.48,;1.81,-1.45,;.48,-2.22,;-.99,-1.74,;-1.61,-.34,;-.84,1,;.7,1,;1.47,2.33,;.7,3.66,;1.47,5,;3.01,5,;4.55,5,;-.84,3.66,;-1.61,2.33,)|
O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1
FC1(F)CCN(Cc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)CC1