SMILES for Programmed cell death 1 ligand 1 [19-238]/protein 1 [25-167]

1797 SMILES Strings for Programmed cell death 1 ligand 1 [19-238]/protein 1 [25-167]

Compound Name

SMILES String

BDBM395339

Cc1c(cccc1-c1cccc(NC(=O)c2ccc(CNCCO)cn2)c1Cl)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)cc(Cl)c2o1 |r|

BDBM395389

Cc1c(cccc1-c1cccc(NC(=O)c2ccc(CN3CC[C@H](O)C3)cn2)c1Cl)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)cc(Cl)c2o1 |r|

BDBM395390

Cc1c(Nc2nccc3cc(CNCCO)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCCC[C@H]4C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395391

Cc1c(Nc2nccc3cc(CNCC(C)(C)O)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCCC[C@H]4C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395392

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCCC[C@H]4C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395393

Cc1c(Nc2nccc3cc(CNCCO)cnc23)cccc1-c1cccc(-c2nc3cc(CNCCC(O)=O)cc(Cl)c3o2)c1C

BDBM395394

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CCCC[C@H]4C(O)=O)c(OCC#N)cc3o2)c1C)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)c(OCC#N)cc2o1 |r|

BDBM395395

CN1CCc2nc(sc2C1)C(=O)Nc1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CCCC[C@H]4C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395396

CN1CCc2nc(sc2C1)C(=O)Nc1cccc(c1Cl)-c1cccc(-c2nc3cc(CNCCO)cc(Cl)c3o2)c1C

BDBM395397

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(Cl)c3o2)c1C)-c1nc2cc(CN3CC[C@H](O)C3)cc(Cl)c2o1 |r|

BDBM395398

Cc1c(Nc2nccc3nccnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395399

Cc1c(Nc2nccc3nccnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395400

Cc1c(Nc2ncnc3cccnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395401

Cc1c(cccc1-c1cccc(Nc2nccc3nccnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395402

Cc1c(cccc1-c1cccc(Nc2cncc3nccnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395403

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395404

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395405

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395406

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395407

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNCCC(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395408

CN(CCC(O)=O)Cc1cc(Cl)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)c1C |r|

BDBM395409

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395410

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC(C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395411

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395412

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395413

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395414

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCCC[C@H]4C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395415

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395416

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM395417

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395418

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CCOC4=O)cnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395419

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM395420

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395421

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@](C)(C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395422

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCC[C@H]4C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395423

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CC[C@@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395424

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CC[C@@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395425

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CC[C@@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395426

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CC2)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395427

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CC(F)(F)C2)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395428

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CC[C@@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395429

CN(CCC(O)=O)Cc1cc(Cl)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(C)CCc3n2C)c1C

BDBM395430

CNC1CCN(CC1)c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395431

Cc1c(cccc1-c1cccc(N2CCC(CC2)NC2CC2)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM395432

Cc1c(cccc1-c1cccc(N2CCC(CC2)N[C@@H]2C[C@H](O)C2)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1 |r,wU:19.20,21.23,wD:35.41,(-1.07,1.78,;-1.07,.24,;.26,-.53,;.26,-2.07,;-1.07,-2.84,;-2.4,-2.07,;-2.4,-.53,;-3.74,.24,;-3.74,1.78,;-5.07,2.55,;-6.41,1.78,;-6.41,.24,;-7.74,-.53,;-9.07,.24,;-10.41,-.53,;-10.41,-2.07,;-9.07,-2.84,;-7.74,-2.07,;-11.74,-2.84,;-11.74,-4.38,;-12.83,-5.47,;-11.74,-6.56,;-11.74,-8.1,;-10.65,-5.47,;-5.07,-.53,;-5.07,-2.07,;1.6,.24,;1.76,1.77,;3.26,2.09,;4.03,3.42,;5.57,3.42,;6.34,4.76,;7.88,4.76,;8.79,3.51,;10.25,3.99,;10.25,5.53,;8.79,6,;11.34,6.61,;12.83,6.22,;10.94,8.1,;6.34,2.09,;5.57,.75,;6.34,-.58,;4.03,.75,;3,-.39,)|

BDBM395433

Cc1c(cccc1-c1cccc(N2CCC(CC2)NCC2(CO)CCC2)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM395434

Cc1c(cccc1-c1cccc(N2CCC(CC2)N[C@@H]2C[C@H](O)C2)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r,wU:19.20,21.23,wD:35.41,(-1.07,1.78,;-1.07,.24,;.26,-.53,;.26,-2.07,;-1.07,-2.84,;-2.4,-2.07,;-2.4,-.53,;-3.74,.24,;-3.74,1.78,;-5.07,2.55,;-6.41,1.78,;-6.41,.24,;-7.74,-.53,;-9.07,.24,;-10.41,-.53,;-10.41,-2.07,;-9.07,-2.84,;-7.74,-2.07,;-11.74,-2.84,;-11.74,-4.38,;-12.83,-5.47,;-11.74,-6.56,;-11.74,-8.1,;-10.65,-5.47,;-5.07,-.53,;-5.07,-2.07,;1.6,.24,;1.76,1.77,;3.26,2.09,;4.03,3.42,;5.57,3.42,;6.34,4.76,;7.88,4.76,;8.79,3.51,;10.25,3.99,;10.25,5.53,;8.79,6,;11.34,6.61,;12.83,6.22,;10.94,8.1,;6.34,2.09,;5.57,.75,;6.34,-.58,;7.11,-1.91,;4.03,.75,;3,-.39,)|

BDBM395435

CCN(CCO)C1CCN(CC1)c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395436

CCN([C@@H]1C[C@H](O)C1)C1CCN(CC1)c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r,wU:3.2,5.5,wD:35.40,(-12.95,-.53,;-12.95,-2.07,;-11.62,-2.84,;-11.62,-4.38,;-12.71,-5.47,;-11.62,-6.56,;-11.62,-8.1,;-10.53,-5.47,;-10.28,-2.07,;-10.28,-.53,;-8.95,.24,;-7.62,-.53,;-7.62,-2.07,;-8.95,-2.84,;-6.28,.24,;-6.28,1.78,;-4.95,2.55,;-3.62,1.78,;-3.62,.24,;-4.95,-.53,;-4.95,-2.07,;-2.28,-.53,;-2.28,-2.07,;-.95,-2.84,;.38,-2.07,;.38,-.53,;1.72,.24,;1.88,1.77,;3.39,2.09,;4.16,3.42,;5.7,3.42,;6.47,4.76,;8.01,4.76,;8.91,3.51,;10.38,3.99,;10.38,5.53,;8.91,6,;11.46,6.61,;12.95,6.22,;11.07,8.1,;6.47,2.09,;5.7,.75,;6.47,-.58,;7.24,-1.91,;4.16,.75,;3.13,-.39,;-.95,.24,;-.95,1.78,)|

BDBM395437

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395438

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1F)-c1cccc(-c3nc4cc(CN5CC[C@@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395439

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CCCC[C@H]5C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395440

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395441

CN1CCc2nn(cc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395442

CN1Cc2cn(nc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395443

CC(C)N1Cc2cn(nc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395444

CN1CCc2cn(nc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395445

CCN1CCc2cn(nc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395447

CC(C)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395448

CCN1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395449

Cc1c(cccc1-c1cccc(-c2nc3CCN(CCO)Cc3s2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM395450

CC(CO)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395451

CC(C)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395452

Cc1c(cccc1-c1cccc(-c2nc3CCN(CC4CC4)Cc3s2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395453

Cc1c(cccc1-c1cccc(-c2nc3CCN(CCO)Cc3s2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395454

CC(CO)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395455

Cc1c(cccc1-c1cccc(-c2nc3CCN(CCO)Cc3s2)c1C)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395456

Cc1c(cccc1-c1cccc(-c2nc3CCN(CCO)Cc3s2)c1C)-c1nc2cc(CN3CC(C3)C(O)=O)cc(C#N)c2o1

BDBM395457

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1Cl)-c1nc2CCNCc2s1 |r|

BDBM395458

Cc1c(cccc1-c1cccc(-c2nc3CCNCc3s2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM395459

CN1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395460

Cc1c(cccc1-c1cccc(-c2nc3CCNCc3s2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395461

CN1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395462

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C)-c1nc2CNCCc2o1 |r|

BDBM395463

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CNCCc2o1 |r|

BDBM395464

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(Cl)c3o2)c1C)-c1nc2CNCCc2o1 |r|

BDBM395465

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC(C4)C(O)=O)cc(Cl)c3o2)c1C)-c1nc2CNCCc2o1

BDBM395466

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C)-c1nc2CCNCc2o1 |r|

BDBM395467

CN1CCc2nc(sc2C1(C)C)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395468

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395469

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM395470

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM395471

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395472

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395473

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395474

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNCC(C)(C)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395475

CC(C)N1CCc2cn(nc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395476

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395477

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CCC(CC5)C(O)=O)cc(C#N)c4o3)c1C)n2C

BDBM395478

C[C@H](NCc1cc(C#N)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(C)CCc3n2C)c1Cl)C(O)=O |r|

BDBM395479

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN[C@H]5CC[C@@H](CC5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r,wU:34.39,wD:31.32,(-13.83,-4.9,;-13.06,-3.57,;-13.83,-2.24,;-13.06,-.9,;-11.52,-.9,;-10.75,-2.24,;-11.52,-3.57,;-9.24,-1.92,;-9.08,-.38,;-7.75,.38,;-7.75,1.93,;-6.41,-.38,;-5.08,.38,;-5.08,1.93,;-3.75,2.69,;-2.41,1.93,;-2.41,.38,;-3.75,-.38,;-3.75,-1.93,;-1.08,-.38,;-1.08,-1.93,;.25,-2.69,;1.59,-1.93,;1.59,-.38,;2.92,.38,;3.08,1.92,;4.59,2.24,;5.36,3.57,;6.9,3.57,;7.67,4.9,;9.21,4.9,;9.98,3.57,;9.21,2.24,;9.98,.9,;11.52,.9,;12.29,2.24,;11.52,3.57,;12.29,-.43,;11.52,-1.76,;13.83,-.43,;7.67,2.24,;6.9,.9,;7.67,-.43,;8.44,-1.76,;5.36,.9,;4.33,-.24,;.25,.38,;.25,1.93,;-10.49,.24,;-10.89,1.73,)|

BDBM395480

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CNCCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395481

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CCO)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395482

CN1Cc2nc(C(=O)Nc3cccc(c3Cl)-c3cccc(-c4nc5cc(CN6CC[C@@H](C6)C(O)=O)cc(C#N)c5o4)c3C)n(C)c2C1 |r|

BDBM395483

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395484

Cc1c(Nc2nccc3cc(cnc23)C2CN(CCO)C2)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395485

Cc1c(cccc1-c1cccc(Nc2nccc3cc(cnc23)C2CCCN2)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395486

Cc1c(Nc2nccc3cc(cnc23)C2CCCN2)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395488

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395489

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNCCC(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395490

Cc1c(Nc2nccc(CN3CC[C@@H](O)C3)c2F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395491

CNC(=O)[C@@H]1CCN(Cc2cc(C#N)c3oc(nc3c2)-c2cccc(c2C)-c2cccc(c2Cl)-n2cc3CCN(Cc3n2)C(C)C)C1 |r|

BDBM395492

CC(C)N1CCc2cn(nc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(=O)NCCO)cc(C#N)c3o2)c1C |r|

BDBM395493

CN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395494

CN(C)CCC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395495

CN1CCC[C@H]1C(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395496

CN1CCN(CC(=O)N2Cc3nc(sc3C2)-c2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c2C)CC1 |r|

BDBM395497

CN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395498

CC(C)NCC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395499

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@@H](O)C2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395500

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@H](O)C2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395501

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CCC2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395502

CCN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395503

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@](C)(O)C2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395504

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@@](C)(O)C2)c1C)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395505

CNC(=O)[C@@H]1CCN(Cc2cc(C#N)c3oc(nc3c2)-c2cccc(c2C)-c2cccc(-c3nc4CCN(Cc4s3)C(C)C)c2C)C1 |r|

BDBM395506

CC(C)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CNCCNC(C)=O)cc(C#N)c3o2)c1C

BDBM395507

CC(C)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(=O)NCCO)cc(C#N)c3o2)c1C |r|

BDBM395508

CC(C)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CNCCO)cc(C#N)c3o2)c1C

BDBM395509

CC(C)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@@H](O)C4)cc(C#N)c3o2)c1C |r|

BDBM395510

CN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395511

CN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC(C4)C(O)=O)cc(C#N)c3o2)c1C

BDBM395512

CN1CCC[C@H]1C(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395513

CN(C)CCC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395514

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CC[C@@H](O)C1 |r|

BDBM395515

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CC(O)C1 |r|

BDBM395516

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CC[C@H](O)C1 |r|

BDBM395517

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CC(C)(O)C1 |r|

BDBM395518

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CCC1 |r|

BDBM395519

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](O)C4)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CC[C@@H](C1)C(O)=O |r|

BDBM395520

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](O)C4)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CC[C@H](C1)C(O)=O |r|

BDBM395521

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](O)C4)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CCCC[C@H]1C(O)=O |r|

BDBM395522

Cc1c(Nc2nccc3cc(CN4CCCC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395523

Cc1c(Nc2nccc3cc(CN4CCC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395524

Cc1c(Nc2nccc3cc(CN4CC(O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395525

Cc1c(Nc2nccc3cc(CN4CC[C@@](C)(O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395526

Cc1c(Nc2nccc3cc(CN4CC[C@](C)(O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395527

Cc1c(Nc2ncnc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395528

CC(N1CC[C@@H](O)C1)c1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@H](C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395529

Cc1c(Nc2nccc3cc(CN4CC[C@H](C4)C(O)=O)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](O)C4)cc(C#N)c3o2)c1C |r|

BDBM395530

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395531

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395532

Cc1c(Nc2nccc3c(CN4CC[C@H](O)C4)ccnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395533

Cc1c(Nc2nccc3c(CN4CC[C@H](O)C4)ccnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395534

C[C@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@H](C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395535

C[C@@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@H](C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395536

Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN3CC[C@@H](O)C3)cc2Cl)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395537

Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN3CCCC[C@H]3C(O)=O)cc2Cl)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395538

Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CNCCO)cc2Cl)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395539

Cc1c(cccc1-c1cccc(NC(=O)c2cc(CN3CC[C@H](C3)C(O)=O)cn(C)c2=O)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(Cl)c2o1 |r|

BDBM395540

Cc1c(Nc2nccn3c(CN4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395541

Cc1nc(CN2CC[C@H](O)C2)cnc1OCc1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CCC(C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM395542

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CNCCc3n2C)c1Cl)-c1nc2cc(CN3CCC(CC3)C(O)=O)cc(C#N)c2o1

BDBM395543

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CCC(CC5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395544

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CCO)CCc3n2C)c1Cl)-c1nc2cc(CN3CCC(CC3)C(O)=O)cc(C#N)c2o1

BDBM395545

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395546

CN1Cc2nc(C(=O)Nc3cccc(c3Cl)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)n(C)c2C1 |r|

BDBM395547

CC1Cc2c(CN1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395548

CC1Cc2c(CN1C)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395549

CC1Cc2c(CN1C)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395550

CC1Cc2c(CN1C)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CCC(CC5)C(O)=O)cc(C#N)c4o3)c1C)n2C

BDBM395551

CC1Cc2c(CN1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395552

CC1Cc2c(CN1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4cc(CN5CCC(CC5)C(O)=O)cc(C#N)c4o3)c1C)n2C

BDBM395553

CN1Cc2nc(C(=O)Nc3cccc(c3Cl)-c3cccc(-c4nc5cc(CN6CC[C@@H](O)C6)cc(C#N)c5o4)c3C)n(C)c2CC1(C)C(O)=O |r|

BDBM395554

Cc1c(Nc2nccc3cc(cnc23)C2=NCCN2)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r,t:16|

BDBM395555

Cc1c(Nc2nccc3cc(CCN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395556

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1Cl |r|

BDBM395557

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN[C@H]4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395558

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN[C@@H]4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395559

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNCCc4ccc(cc4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395560

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNC4CC[C@@H](CC4)C(O)=O)cc(C#N)c3o2)c1C |r,wU:40.47,wD:15.15,(-2.36,-1.18,;-2.36,.36,;-3.69,1.13,;-5.02,.36,;-6.36,1.13,;-6.36,2.67,;-7.69,3.44,;-9.02,2.67,;-9.02,1.13,;-10.36,.36,;-10.36,-1.18,;-11.69,-1.95,;-13.03,-1.18,;-13.03,.36,;-14.49,.83,;-15.39,-.41,;-16.93,-.41,;-14.49,-1.66,;-9.02,-1.95,;-7.69,-1.18,;-7.69,.36,;-3.69,2.67,;-2.36,3.44,;-1.02,2.67,;-1.02,1.13,;.31,.36,;.31,-1.18,;1.65,-1.95,;2.98,-1.18,;2.98,.36,;4.31,1.13,;4.31,2.67,;6.98,2.67,;8.31,3.44,;9.65,2.67,;10.98,3.44,;12.31,2.67,;13.08,1.33,;12.31,,;13.08,-1.33,;14.65,-1.38,;15.39,,;14.62,1.33,;15.42,-2.72,;16.96,-2.72,;14.65,-4.05,;9.65,1.13,;8.31,.36,;8.31,-1.18,;8.31,-2.72,;6.98,1.13,;5.65,.36,;1.65,1.13,;1.65,2.67,)|

BDBM395561

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](CC(O)=O)C4)cc(C#N)c3o2)c1C |r|

BDBM395562

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](CC(O)=O)C4)cc(C#N)c3o2)c1C |r|

BDBM395563

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNC4CCCC4)cc(C#N)c3o2)c1C |r|

BDBM395564

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC5CC4CC5C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395565

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC5(CC(C5)C(O)=O)C4)cc(C#N)c3o2)c1C |r|

BDBM395566

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC5(CC4C5)C(O)=O)cc(C#N)c3o2)c1C |r,wD:15.15,(-2.39,-1.54,;-2.39,,;-3.72,.77,;-5.05,,;-6.39,.77,;-6.39,2.31,;-7.72,3.08,;-9.05,2.31,;-9.05,.77,;-10.39,,;-10.39,-1.54,;-11.72,-2.31,;-13.06,-1.54,;-13.06,,;-14.52,.48,;-15.43,-.77,;-16.97,-.77,;-14.52,-2.02,;-9.05,-2.31,;-7.72,-1.54,;-7.72,,;-3.72,2.31,;-2.39,3.08,;-1.05,2.31,;-1.05,.77,;.28,,;.28,-1.54,;1.62,-2.31,;2.95,-1.54,;2.95,,;4.28,.77,;4.28,2.31,;6.95,2.31,;8.28,3.08,;9.62,2.31,;10.95,3.08,;12.29,2.31,;13.75,2.79,;14.83,1.5,;13.75,.29,;12.29,.77,;13.37,1.86,;16.37,1.48,;17.11,.13,;17.16,2.8,;9.62,.77,;8.28,,;8.28,-1.54,;8.28,-3.08,;6.95,.77,;5.62,,;1.62,.77,;1.62,2.31,)|

BDBM395568

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN[C@H]4CC(C4)C(O)=O)cc(C#N)c3o2)c1C |r,wU:37.40,wD:15.15,(-3.1,-2.58,;-3.1,-1.04,;-4.43,-.27,;-5.77,-1.04,;-7.1,-.27,;-7.1,1.27,;-8.43,2.04,;-9.77,1.27,;-9.77,-.27,;-11.1,-1.04,;-11.1,-2.58,;-12.44,-3.35,;-13.77,-2.58,;-13.93,-1.05,;-15.44,-.73,;-16.21,-2.06,;-17.74,-2.22,;-15.18,-3.21,;-9.77,-3.35,;-8.43,-2.58,;-8.43,-1.04,;-4.43,1.27,;-3.1,2.04,;-1.77,1.27,;-1.77,-.27,;-.43,-1.04,;-.43,-2.58,;.9,-3.35,;2.23,-2.58,;2.23,-1.04,;3.57,-.27,;3.57,1.27,;6.24,1.27,;7.57,2.04,;8.9,1.27,;10.24,2.04,;11.57,1.27,;13.06,1.67,;13.83,3,;15.16,2.23,;14.39,.9,;16.65,2.63,;17.74,1.54,;17.05,4.12,;8.9,-.27,;7.57,-1.04,;7.57,-2.58,;7.57,-4.12,;6.24,-.27,;4.9,-1.04,;.9,-.27,;.9,1.27,)|

BDBM395570

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN[C@H]4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395571

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNC45CCC(CC4)(C5)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395572

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNC4CC[C@H](CC(O)=O)CC4)cc(C#N)c3o2)c1C |r,wD:15.15,40.44,(-3.48,-1.54,;-3.48,,;-4.82,.77,;-6.15,,;-7.48,.77,;-7.48,2.31,;-8.82,3.08,;-10.15,2.31,;-10.15,.77,;-11.48,,;-11.48,-1.54,;-12.82,-2.31,;-14.15,-1.54,;-14.31,-.01,;-15.82,.31,;-16.59,-1.02,;-18.12,-1.18,;-15.56,-2.17,;-10.15,-2.31,;-8.82,-1.54,;-8.82,,;-4.82,2.31,;-3.48,3.08,;-2.15,2.31,;-2.15,.77,;-.81,,;-.81,-1.54,;.52,-2.31,;1.85,-1.54,;1.85,,;3.19,.77,;3.19,2.31,;5.85,2.31,;7.19,3.08,;8.52,2.31,;9.85,3.08,;11.19,2.31,;12.28,1.22,;13.76,1.62,;14.85,.53,;14.45,-.96,;15.54,-2.05,;15.15,-3.53,;13.66,-3.93,;16.23,-4.62,;12.97,-1.36,;11.88,-.27,;8.52,.77,;7.19,,;7.19,-1.54,;7.19,-3.08,;5.85,.77,;4.52,,;.52,.77,;.52,2.31,)|

BDBM395573

COCC1(CCN(Cc2cc(C#N)c3oc(nc3c2)-c2cccc(c2C)-c2cccc(Nc3nccc4cc(CN5CC[C@@H](O)C5)cnc34)c2C)C1)C(O)=O |r|

BDBM395574

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395575

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@](C)(C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395576

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CCC(CC3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395577

Cc1c(Nc2nccc3cc(CNCCO)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395578

CN(CCO)Cc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395579

C[C@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395580

C[C@@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395581

Cc1c(Nc2nccc3cc(CN4CCCC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395582

CC[C@@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395583

C[C@@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395584

C[C@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395585

CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395586

Cc1c(Nc2nccc3cc(CNC(C)(C)CO)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395587

Cc1c(Nc2nccc3cc(CNCC4(O)CC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395588

Cc1c(Nc2nccc3cc(CN4CC[C@](C)(O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395589

C[C@@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CCC(CC6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395590

C[C@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CCC(CC6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395591

C[C@@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CCC(CC6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395592

C[C@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CCC(CC6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395593

Cc1c(Nc2ncnc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395594

Cc1c(Nc2ncnc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395595

Cc1c(Nc2ncnc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395597

C[C@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)ncnc2c1 |r|

BDBM395599

C[C@H](O)CNCc1cc(C#N)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(Nc2nccc3cc(CN4CCCC4)cnc23)c1C |r|

BDBM395600

C[C@@H](CO)NCc1cc(C#N)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(Nc2nccc3cc(CN4CCCC4)cnc23)c1C |r|

BDBM395601

C[C@H](O)CNCc1cc(C#N)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(Nc2nccc3cc(CN4CCCCC4)cnc23)c1C |r|

BDBM395602

C[C@@H](CO)NCc1cc(C#N)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(Nc2nccc3cc(CN4CCCCC4)cnc23)c1C |r|

BDBM395603

Cc1c(Nc2nccc3cc(CN4CCCCC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](O)C4)cc(C#N)c3o2)c1C |r|

BDBM395604

C[C@@H](CO)NCc1cc(C#N)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(Nc2nccc3cc(CN4CC[C@H](C)C4)cnc23)c1C |r|

BDBM395605

C[C@H]1CCN(Cc2cnc3c(Nc4cccc(c4C)-c4cccc(-c5nc6cc(CN7CC[C@@H](O)C7)cc(C#N)c6o5)c4C)nccc3c2)C1 |r|

BDBM395606

CC(C)N(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395607

CCN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395608

CN(CC1CC1)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395609

CCN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5(CC4C5)C(O)=O)cc(C#N)c3o2)c1C |(-15.97,5.64,;-14.43,5.64,;-13.66,4.31,;-14.43,2.98,;-12.12,4.31,;-11.35,2.98,;-12.12,1.64,;-9.81,2.98,;-8.91,1.73,;-7.44,2.21,;-5.98,1.73,;-5.07,2.98,;-5.98,4.22,;-7.44,3.75,;-8.91,4.22,;-3.53,2.98,;-2.76,4.31,;-1.22,4.31,;-.45,2.98,;-1.22,1.64,;-2.76,1.64,;-3.53,.31,;-.45,.31,;-1.22,-1.02,;-.45,-2.36,;1.09,-2.36,;1.86,-1.02,;3.4,-1.02,;4.3,.22,;5.77,-.25,;7.1,.52,;8.43,-.25,;9.77,.52,;11.1,-.25,;12.51,.37,;13.54,-.77,;12.77,-2.11,;11.26,-1.79,;12.21,-.7,;15.07,-.61,;15.97,-1.86,;15.7,.8,;8.43,-1.79,;7.1,-2.56,;7.1,-4.1,;7.1,-5.64,;5.77,-1.79,;4.3,-2.27,;1.09,.31,;1.86,1.64,)|

BDBM395610

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@H](O)C2)c1C)-c1nc2cc(CN3CC[C@](C)(C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395611

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@@H](O)C2)c1C)-c1nc2cc(CN3CC[C@](C)(C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395612

CCN1CCN(CC(=O)N2Cc3nc(sc3C2)-c2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c2C)CC1 |r|

BDBM395613

CN(CCO)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395614

C[C@H](CO)N(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395615

C[C@@H](CO)N(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395616

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC(O)C2)c1C)-c1nc2cc(CN3CC[C@](C)(C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395618

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CNC2C[C@H](O)C2)c1C)-c1nc2cc(CN3CC[C@](C)(C3)C(O)=O)cc(C#N)c2o1 |r,wU:40.45,26.29,wD:40.48,(1.85,2.31,;1.08,.98,;1.85,-.36,;1.08,-1.69,;-.46,-1.69,;-1.23,-.36,;-.46,.98,;-1.23,2.31,;-.46,3.64,;-1.23,4.98,;-2.77,4.98,;-3.54,3.64,;-5.08,3.64,;-5.98,2.4,;-7.45,2.87,;-8.91,2.4,;-9.82,3.64,;-8.91,4.89,;-7.45,4.41,;-5.98,4.89,;-11.36,3.64,;-12.13,2.31,;-12.13,4.98,;-13.67,4.98,;-14.43,3.64,;-15.92,3.25,;-15.52,1.76,;-16.29,.42,;-14.04,2.16,;-2.77,2.31,;-3.54,.98,;3.39,-.36,;4.3,.89,;5.76,.41,;7.1,1.18,;8.43,.41,;9.77,1.18,;11.1,.41,;11.26,-1.12,;12.77,-1.44,;13.54,-.11,;14.62,.98,;12.51,1.04,;14.87,-.88,;16.29,-.18,;14.77,-2.37,;8.43,-1.13,;7.1,-1.9,;7.1,-3.44,;7.1,-4.98,;5.76,-1.13,;4.3,-1.6,)|

BDBM395619

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CNC2C[C@H](O)C2)c1C)-c1nc2cc(CN3CC[C@](C)(C3)C(O)=O)cc(C#N)c2o1 |r,wU:40.45,wD:40.48,26.29,(1.85,2.31,;1.08,.98,;1.85,-.36,;1.08,-1.69,;-.46,-1.69,;-1.23,-.36,;-.46,.98,;-1.23,2.31,;-.46,3.64,;-1.23,4.98,;-2.77,4.98,;-3.54,3.64,;-5.08,3.64,;-5.98,2.4,;-7.45,2.87,;-8.91,2.4,;-9.82,3.64,;-8.91,4.89,;-7.45,4.41,;-5.98,4.89,;-11.36,3.64,;-12.13,2.31,;-12.13,4.98,;-13.67,4.98,;-14.43,3.64,;-14.04,2.16,;-15.52,1.76,;-16.29,.42,;-15.92,3.25,;-2.77,2.31,;-3.54,.98,;3.39,-.36,;4.3,.89,;5.76,.41,;7.1,1.18,;8.43,.41,;9.77,1.18,;11.1,.41,;11.26,-1.12,;12.77,-1.44,;13.54,-.11,;14.62,.98,;12.51,1.04,;14.87,-.88,;16.29,-.18,;14.77,-2.37,;8.43,-1.13,;7.1,-1.9,;7.1,-3.44,;7.1,-4.98,;5.76,-1.13,;4.3,-1.6,)|

BDBM395620

CN(CCO)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5(CC(C5)C(O)=O)C4)cc(C#N)c3o2)c1C

BDBM395621

C[C@H](CO)N(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5(CC(C5)C(O)=O)C4)cc(C#N)c3o2)c1C |r|

BDBM395622

C[C@@H](CO)N(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5(CC(C5)C(O)=O)C4)cc(C#N)c3o2)c1C |r|

BDBM395623

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@H](O)C2)c1C)-c1nc2cc(CN3CC4(CC(C4)C(O)=O)C3)cc(C#N)c2o1 |r|

BDBM395624

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@@H](O)C2)c1C)-c1nc2cc(CN3CC4(CC(C4)C(O)=O)C3)cc(C#N)c2o1 |r|

BDBM395625

CN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5(CC4C5)C(O)=O)cc(C#N)c3o2)c1C |(-15.2,5.64,;-14.43,4.31,;-15.2,2.98,;-12.89,4.31,;-12.12,2.98,;-12.89,1.64,;-10.58,2.98,;-9.68,1.73,;-8.21,2.21,;-6.75,1.73,;-5.84,2.98,;-6.75,4.22,;-8.21,3.75,;-9.68,4.22,;-4.3,2.98,;-3.53,4.31,;-1.99,4.31,;-1.22,2.98,;-1.99,1.64,;-3.53,1.64,;-4.3,.31,;-1.22,.31,;-1.99,-1.02,;-1.22,-2.36,;.32,-2.36,;1.09,-1.02,;2.63,-1.02,;3.53,.22,;5,-.25,;6.33,.52,;7.66,-.25,;9,.52,;10.33,-.25,;11.74,.37,;12.77,-.77,;12,-2.11,;10.49,-1.79,;11.45,-.7,;14.3,-.61,;15.2,-1.86,;14.93,.8,;7.66,-1.79,;6.33,-2.56,;6.33,-4.1,;6.33,-5.64,;5,-1.79,;3.53,-2.27,;.32,.31,;1.09,1.64,)|

BDBM395626

CN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C

BDBM395627

CN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5CC4CC5C(O)=O)cc(C#N)c3o2)c1C

BDBM395628

CC(C)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(=O)NS(C)(=O)=O)cc(C#N)c3o2)c1C |r|

BDBM395629

CC(C)N1CCc2cn(nc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC(C4)C(O)=O)cc(C#N)c3o2)c1C

BDBM395630

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(Cc4ccc(cc4)B(O)O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r|

BDBM395631

CCN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395632

CCN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5(CC4C5)C(O)=O)cc(C#N)c3o2)c1C |(-15.88,5.64,;-14.34,5.64,;-13.57,4.31,;-14.34,2.98,;-12.03,4.31,;-11.26,2.98,;-12.03,1.64,;-9.72,2.98,;-8.81,4.22,;-7.35,3.75,;-5.88,4.22,;-4.98,2.98,;-5.88,1.73,;-7.35,2.21,;-8.81,1.73,;-3.44,2.98,;-2.67,4.31,;-1.13,4.31,;-.36,2.98,;-1.13,1.64,;-2.67,1.64,;-3.44,.31,;-.36,.31,;-1.13,-1.02,;-.36,-2.36,;1.18,-2.36,;1.95,-1.02,;3.49,-1.02,;4.4,.22,;5.86,-.25,;7.2,.52,;8.53,-.25,;9.86,.52,;11.2,-.25,;12.66,.22,;13.57,-1.02,;12.66,-2.27,;11.2,-1.79,;12.29,-.71,;15.11,-1.02,;15.88,-2.36,;15.88,.31,;8.53,-1.79,;7.2,-2.56,;7.2,-4.1,;7.2,-5.64,;5.86,-1.79,;4.4,-2.27,;1.18,.31,;1.95,1.64,)|

BDBM395633

CCN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395634

CCN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C

BDBM395635

CN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395636

CN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C

BDBM395637

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CC[C@@H](O)C1 |r|

BDBM395638

CC(C)N(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395639

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CCC(O)CC1 |r|

BDBM395640

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CCC(O)CC1 |r|

BDBM395641

Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC5CC4CC5C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CCC(O)CC1

BDBM395642

CN(CCCO)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395643

CN1CCN(CC(=O)N2Cc3nc(oc3C2)-c2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC6CC5CC6C(O)=O)cc(C#N)c4o3)c2C)CC1

BDBM395644

CN1CCN(CC(=O)N2Cc3nc(oc3C2)-c2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c2C)CC1 |r|

BDBM395645

CN1CC2CC1CN2CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM395646

Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3o2)C(=O)CN2CC[C@@H](O)C2)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM395647

C[C@@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@H](C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395648

C[C@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@H](C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1 |r|

BDBM395649

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CCC(CC5)C(O)=O)cc(C#N)c4o3)c1C)n2C

BDBM395650

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM395651

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r,wU:24.28,wD:21.21,46.51,(4.58,1.42,;4.18,-.07,;5.27,-1.15,;4.87,-2.64,;3.39,-3.04,;2.3,-1.95,;2.7,-.46,;1.61,.62,;2.01,2.11,;.92,3.2,;-.57,2.8,;-.97,1.31,;-2.46,.92,;-3.55,2,;-3.15,3.49,;-5.03,1.61,;-5.51,.14,;-7.05,.14,;-8.08,-1,;-9.59,-.68,;-10.68,-1.77,;-12.16,-1.37,;-12.56,.11,;-14.05,.51,;-15.14,-.58,;-14.74,-2.06,;-13.25,-2.46,;-16.63,-.18,;-17.02,1.31,;-17.71,-1.27,;-10.06,.78,;-9.03,1.93,;-7.53,1.61,;-6.28,2.51,;-6.28,4.05,;.12,.23,;-.28,-1.26,;6.76,-.76,;7.24,.71,;8.78,.71,;9.81,1.85,;11.31,1.53,;12.4,2.62,;13.89,2.22,;14.36,.76,;15.9,.76,;16.38,2.22,;17.71,2.99,;15.13,3.13,;11.79,.07,;10.76,-1.08,;11.16,-2.56,;11.56,-4.05,;9.25,-.76,;8.01,-1.66,)|

BDBM395652

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CC45CC(C4)(C5)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r|

BDBM395653

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CC(C)(C2)C(O)=O)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r,wD:44.49,(2.98,2.56,;2.66,1.06,;3.81,.03,;3.49,-1.48,;2.02,-1.95,;.88,-.92,;1.2,.58,;.05,1.61,;.37,3.12,;-.77,4.15,;-2.24,3.67,;-2.56,2.17,;-4.02,1.69,;-5.16,2.72,;-4.84,4.23,;-6.63,2.25,;-7.1,.78,;-8.64,.78,;-9.68,-.36,;-11.18,-.04,;-11.66,1.42,;-10.63,2.57,;-9.12,2.25,;-7.88,3.15,;-7.88,4.69,;-12.21,-1.19,;-13.75,-1.27,;-13.67,-2.81,;-13.67,-4.35,;-12.13,-2.72,;-15.16,-3.2,;-15.56,-4.69,;-16.25,-2.11,;-1.41,1.14,;-1.73,-.37,;5.27,.5,;5.75,1.97,;7.29,1.97,;8.32,3.11,;9.82,2.79,;10.85,3.94,;12.36,3.62,;12.99,2.21,;14.52,2.37,;14.84,3.88,;16.25,4.5,;13.51,4.65,;10.3,1.33,;9.27,.18,;9.75,-1.28,;10.22,-2.75,;7.76,.5,;6.52,-.4,)|

BDBM395654

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCCC(CC2)C(O)=O)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r|

BDBM395655

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CCC4CCC(CC4)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r,wD:47.52,(4.53,3.67,;4.21,2.17,;5.36,1.14,;5.04,-.37,;3.57,-.85,;2.43,.19,;2.75,1.69,;1.6,2.72,;1.92,4.23,;.78,5.26,;-.68,4.78,;-1.01,3.28,;-2.47,2.8,;-3.61,3.83,;-3.29,5.34,;-5.08,3.36,;-5.55,1.89,;-7.09,1.89,;-8.12,.75,;-9.63,1.07,;-10.66,-.08,;-12.17,.24,;-13.2,-.9,;-14.7,-.58,;-15.74,-1.73,;-15.26,-3.19,;-13.75,-3.51,;-12.72,-2.37,;-16.29,-4.34,;-17.8,-4.02,;-15.81,-5.8,;-10.11,2.53,;-9.08,3.68,;-7.57,3.36,;-6.32,4.26,;-6.32,5.8,;.14,2.25,;-.18,.74,;6.82,1.61,;7.3,3.08,;8.84,3.08,;9.87,4.22,;11.37,3.9,;12.4,5.05,;13.91,4.73,;14.54,3.32,;16.07,3.48,;16.39,4.99,;17.8,5.61,;15.06,5.76,;11.85,2.44,;10.82,1.29,;11.3,-.17,;11.77,-1.64,;9.31,1.61,;8.07,.71,)|

BDBM395656

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r,wD:46.51,21.21,24.28,(4.49,1.59,;4.17,.09,;5.32,-.94,;5,-2.45,;3.53,-2.93,;2.39,-1.9,;2.71,-.39,;1.56,.64,;1.88,2.15,;.74,3.18,;-.72,2.7,;-1.04,1.19,;-2.51,.72,;-3.65,1.75,;-3.33,3.26,;-5.12,1.27,;-5.59,-.19,;-7.13,-.19,;-8.16,-1.34,;-9.67,-1.02,;-10.7,-2.16,;-12.21,-1.84,;-12.68,-.38,;-14.19,-.05,;-15.22,-1.2,;-14.74,-2.66,;-13.24,-2.98,;-16.73,-.88,;-17.2,.59,;-17.76,-2.02,;-10.15,.45,;-9.12,1.59,;-7.61,1.27,;-6.36,2.18,;-6.36,3.72,;.1,.16,;-.22,-1.34,;6.78,-.47,;7.26,1,;8.8,1,;9.83,2.14,;11.34,1.82,;12.37,2.96,;13.87,2.64,;14.5,1.24,;16.03,1.4,;16.35,2.9,;17.76,3.53,;15.02,3.67,;11.81,.36,;10.78,-.79,;11.26,-2.25,;11.73,-3.72,;9.27,-.47,;8.03,-1.37,)|

BDBM395657

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r|

BDBM395658

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CC4CCC(C)(CC4)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r,wD:47.52,(4.58,1.42,;4.18,-.07,;5.27,-1.15,;4.87,-2.64,;3.39,-3.04,;2.3,-1.95,;2.7,-.46,;1.61,.62,;2.01,2.11,;.92,3.2,;-.57,2.8,;-.97,1.31,;-2.46,.92,;-3.55,2,;-3.15,3.49,;-5.03,1.61,;-5.51,.14,;-7.05,.14,;-8.08,-1,;-9.59,-.68,;-10.68,-1.77,;-12.16,-1.37,;-13.25,-2.46,;-14.74,-2.06,;-15.14,-.58,;-15.54,.91,;-14.05,.51,;-12.56,.11,;-16.63,-.18,;-17.02,1.31,;-17.71,-1.27,;-10.06,.78,;-9.03,1.93,;-7.53,1.61,;-6.28,2.51,;-6.28,4.05,;.12,.23,;-.28,-1.26,;6.76,-.76,;7.24,.71,;8.78,.71,;9.81,1.85,;11.31,1.53,;12.4,2.62,;13.89,2.22,;14.36,.76,;15.9,.76,;16.38,2.22,;17.71,2.99,;15.13,3.13,;11.79,.07,;10.76,-1.08,;11.16,-2.56,;11.56,-4.05,;9.25,-.76,;8.01,-1.66,)|

BDBM395659

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CC4CCC(C)(CC4)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1 |r,wD:47.52,(4.58,1.42,;4.18,-.07,;5.27,-1.15,;4.87,-2.64,;3.39,-3.04,;2.3,-1.95,;2.7,-.46,;1.61,.62,;2.01,2.11,;.92,3.2,;-.57,2.8,;-.97,1.31,;-2.46,.92,;-3.55,2,;-3.15,3.49,;-5.03,1.61,;-5.51,.14,;-7.05,.14,;-8.08,-1,;-9.59,-.68,;-10.68,-1.77,;-12.16,-1.37,;-13.25,-2.46,;-14.74,-2.06,;-15.14,-.58,;-16.23,-1.66,;-14.05,.51,;-12.56,.11,;-16.63,-.18,;-17.02,1.31,;-17.71,-1.27,;-10.06,.78,;-9.03,1.93,;-7.53,1.61,;-6.28,2.51,;-6.28,4.05,;.12,.23,;-.28,-1.26,;6.76,-.76,;7.24,.71,;8.78,.71,;9.81,1.85,;11.31,1.53,;12.4,2.62,;13.89,2.22,;14.36,.76,;15.9,.76,;16.38,2.22,;17.71,2.99,;15.13,3.13,;11.79,.07,;10.76,-1.08,;11.16,-2.56,;11.56,-4.05,;9.25,-.76,;8.01,-1.66,)|

BDBM395660

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CC4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC4CC3CC4O)cc(C#N)c2o1 |r,wU:24.28,(4.25,1.42,;3.86,-.07,;4.95,-1.15,;4.55,-2.64,;3.06,-3.04,;1.97,-1.95,;2.37,-.46,;1.28,.62,;1.68,2.11,;.59,3.2,;-.9,2.8,;-1.3,1.31,;-2.78,.92,;-3.87,2,;-3.47,3.49,;-5.36,1.61,;-5.84,.14,;-7.38,.14,;-8.41,-1,;-9.91,-.68,;-11,-1.77,;-12.49,-1.37,;-12.89,.11,;-14.38,.51,;-15.46,-.58,;-15.07,-2.06,;-13.58,-2.46,;-16.95,-.18,;-17.35,1.31,;-18.04,-1.27,;-10.39,.78,;-9.36,1.93,;-7.85,1.61,;-6.61,2.51,;-6.61,4.05,;-.21,.23,;-.61,-1.26,;6.43,-.76,;6.91,.71,;8.45,.71,;9.48,1.85,;10.99,1.53,;12.07,2.62,;13.56,2.22,;13.98,.74,;15.46,.34,;15.46,1.88,;14.67,3.31,;16.16,2.91,;16.55,1.43,;18.04,1.03,;11.46,.07,;10.43,-1.08,;10.83,-2.56,;11.23,-4.05,;8.92,-.76,;7.68,-1.66,)|

BDBM395661

Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CC4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CCCC3)cc(C#N)c2o1 |r,wU:24.28,(5.25,1.42,;4.85,-.07,;5.94,-1.15,;5.54,-2.64,;4.05,-3.04,;2.96,-1.95,;3.36,-.46,;2.27,.62,;2.67,2.11,;1.58,3.2,;.1,2.8,;-.3,1.31,;-1.79,.92,;-2.88,2,;-2.48,3.49,;-4.37,1.61,;-4.84,.14,;-6.38,.14,;-7.41,-1,;-8.92,-.68,;-10.01,-1.77,;-11.5,-1.37,;-11.89,.11,;-13.38,.51,;-14.47,-.58,;-14.07,-2.06,;-12.58,-2.46,;-15.96,-.18,;-16.36,1.31,;-17.05,-1.27,;-9.4,.78,;-8.36,1.93,;-6.86,1.61,;-5.61,2.51,;-5.61,4.05,;.79,.23,;.39,-1.26,;7.43,-.76,;7.9,.71,;9.44,.71,;10.47,1.85,;11.98,1.53,;13.07,2.62,;14.56,2.22,;15.03,.76,;16.57,.76,;17.05,2.22,;15.8,3.13,;12.46,.07,;11.42,-1.08,;11.82,-2.56,;12.22,-4.05,;9.92,-.76,;8.67,-1.66,)|

BDBM438751

Cn1c2CCNCc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438754

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl

BDBM438756

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM438759

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM438762

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM438763

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC2)c1Cl

BDBM438764

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCN(CC2)C(N)=O)c1Cl

BDBM438766

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCN(CC2)S(N)(=O)=O)c1Cl

BDBM438767

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(Cc4cc[nH]n4)CCc3n2C)c1Cl

BDBM438768

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C(CO)CO)c1Cl

BDBM438770

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@@H](O)CO)CCc3n2C)c1Cl |r|

BDBM438771

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H](O)CO)CCc3n2C)c1Cl |r|

BDBM438772

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C |r|

BDBM438773

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C |r|

BDBM438774

Cn1c2CCN(CCO)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438775

Cn1c2CCN(CCCO)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438776

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438777

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438778

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC(O)=O)CCc3n2C)c1Cl

BDBM438780

Cn1c2CCN(CCCC(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438781

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC(C)(C)C(O)=O)CCc3n2C)c1Cl

BDBM438782

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC4(CC4)C(O)=O)CCc3n2C)c1Cl

BDBM438783

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(CC5)C(O)=O)CCc3n2C)c1Cl

BDBM438784

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC45CC(C4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438785

Cn1c2CCN(CCc3ccc(cc3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438786

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(Cc4cc(n[nH]4)C(O)=O)CCc3n2C)c1Cl

BDBM438787

Cc1c(NC(=O)c2nc3CNCCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438790

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438791

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM438795

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCN(CC2)C(N)=O)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438796

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C |r|

BDBM438797

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C |r|

BDBM438798

Cc1c(NC(=O)c2nc3CN(CCO)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438799

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438800

Cc1c(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438801

Cc1c(NC(=O)c2nc3CN(CCc4ccc(cc4)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438802

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CNCCc3n2C)c1Cl

BDBM438803

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl

BDBM438804

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1C)n2C

BDBM438805

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCN(CC2)C(N)=O)c1Cl

BDBM438806

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1C)n2C |r|

BDBM438807

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1C)n2C |r|

BDBM438808

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCO)CCc3n2C)c1Cl

BDBM438809

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438810

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCc4ccc(cc4)C(O)=O)CCc3n2C)c1Cl

BDBM438811

Cn1c2CCNCc2nc1C(=O)Nc1cccc(-c2cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c2Cl)c1C#N

BDBM438812

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1C#N

BDBM438813

CN1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CN(CCC67CCC(CC6)(C7)C(O)=O)CCc5n4C)c3Cl)c1C#N)n2C

BDBM438814

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CN(CCC67CCC(CC6)(C7)C(O)=O)CCc5n4C)c3Cl)c1C#N)n2C |r|

BDBM438815

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCO)CCc3n2C)c1C#N

BDBM438816

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1C#N

BDBM438817

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1C#N

BDBM438818

Cc1c(NC(=O)c2nc3CNCCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1C

BDBM438819

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1C

BDBM438820

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1C

BDBM438821

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1C

BDBM438822

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1C)n2C |r|

BDBM438823

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1C)n2C |r|

BDBM438824

Cc1c(NC(=O)c2nc3CN(CCO)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1C

BDBM438825

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)[C@@H]2CC[C@H](O)CC2)c1Cl |r,wU:50.56,53.60,(-7.22,3.06,;-6.82,1.57,;-7.85,.43,;-9.39,.43,;-10.16,-.9,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-11.7,-6.24,;-12.47,-7.57,;-14.01,-7.57,;-14.78,-6.24,;-14.01,-4.9,;-13.61,-6.08,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-7.85,-2.24,;-7.08,-.9,;-5.57,-.58,;-5.41,.95,;-4.08,1.72,;-4.08,3.26,;-2.74,.95,;-1.41,1.72,;-1.41,3.26,;-.08,4.03,;1.26,3.26,;1.26,1.72,;-.08,.95,;-.08,-.59,;2.59,.95,;2.59,-.59,;3.93,-1.36,;5.26,-.59,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;11.07,-.4,;14.01,6.24,;15.55,6.24,;16.32,7.57,;15.55,8.91,;16.32,10.24,;14.01,8.91,;13.24,7.57,;3.93,1.72,;3.93,3.26,)|

BDBM438826

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)[C@H]2CC[C@H](O)CC2)c1Cl |r,wU:50.56,wD:53.60,(-7.22,3.06,;-6.82,1.57,;-7.85,.43,;-9.39,.43,;-10.16,-.9,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-11.7,-6.24,;-12.47,-7.57,;-14.01,-7.57,;-14.78,-6.24,;-14.01,-4.9,;-13.61,-6.08,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-7.85,-2.24,;-7.08,-.9,;-5.57,-.58,;-5.41,.95,;-4.08,1.72,;-4.08,3.26,;-2.74,.95,;-1.41,1.72,;-1.41,3.26,;-.08,4.03,;1.26,3.26,;1.26,1.72,;-.08,.95,;-.08,-.59,;2.59,.95,;2.59,-.59,;3.93,-1.36,;5.26,-.59,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;11.07,-.4,;14.01,6.24,;13.24,7.57,;14.01,8.91,;15.55,8.91,;16.32,10.24,;16.32,7.57,;15.55,6.24,;3.93,1.72,;3.93,3.26,)|

BDBM438827

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl |(3.93,3.26,;3.93,1.72,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;11.07,-.4,;14.01,6.24,;15.55,6.24,;16.32,7.57,;15.55,8.91,;16.32,10.24,;14.01,8.91,;13.24,7.57,;5.26,-.59,;3.93,-1.36,;2.59,-.59,;2.59,.95,;1.26,1.72,;1.26,3.26,;-.08,4.03,;-1.41,3.26,;-1.41,1.72,;-2.74,.95,;-4.08,1.72,;-4.08,3.26,;-5.41,.95,;-5.57,-.58,;-7.08,-.9,;-7.85,-2.24,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-11.7,-6.24,;-12.47,-7.57,;-14.01,-7.57,;-14.78,-6.24,;-14.01,-4.9,;-13.61,-6.08,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-10.16,-.9,;-9.39,.43,;-7.85,.43,;-6.82,1.57,;-7.22,3.06,;-.08,.95,;-.08,-.59,)|

BDBM438828

Cc1c(NC(=O)c2nc3CN(CCc3n2C)[C@H]2CC[C@H](O)CC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl |r,wU:16.17,wD:19.21,(3.93,3.26,;3.93,1.72,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;11.07,-.4,;14.01,6.24,;13.24,7.57,;14.01,8.91,;15.55,8.91,;16.32,10.24,;16.32,7.57,;15.55,6.24,;5.26,-.59,;3.93,-1.36,;2.59,-.59,;2.59,.95,;1.26,1.72,;1.26,3.26,;-.08,4.03,;-1.41,3.26,;-1.41,1.72,;-2.74,.95,;-4.08,1.72,;-4.08,3.26,;-5.41,.95,;-5.57,-.58,;-7.08,-.9,;-7.85,-2.24,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-11.7,-6.24,;-12.47,-7.57,;-14.01,-7.57,;-14.78,-6.24,;-14.01,-4.9,;-13.61,-6.08,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-10.16,-.9,;-9.39,.43,;-7.85,.43,;-6.82,1.57,;-7.22,3.06,;-.08,.95,;-.08,-.59,)|

BDBM438829

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl |r,wU:8.7,wD:11.14,(9.14,-1.73,;8.74,-.24,;9.77,.9,;11.31,.9,;12.08,2.24,;11.31,3.57,;12.08,4.9,;13.62,4.9,;14.39,6.24,;13.62,7.57,;14.39,8.91,;15.93,8.91,;16.7,7.57,;15.93,6.24,;16.7,10.24,;18.24,10.24,;15.93,11.57,;9.77,3.57,;9,2.24,;7.5,1.92,;7.34,.39,;6,-.39,;6,-1.92,;4.67,.39,;3.33,-.39,;3.33,-1.92,;2,-2.7,;.67,-1.92,;.67,-.39,;2,.39,;2,1.92,;-.67,.39,;-.67,1.92,;-2,2.7,;-3.33,1.92,;-3.33,.39,;-4.67,-.39,;-6,.39,;-6,1.92,;-7.34,-.39,;-7.5,-1.92,;-9,-2.24,;-9.77,-3.57,;-11.31,-3.57,;-12.08,-4.9,;-13.62,-4.9,;-14.39,-6.24,;-13.62,-7.57,;-14.39,-8.91,;-15.93,-8.91,;-16.7,-7.57,;-15.93,-6.24,;-15.53,-7.42,;-16.7,-10.24,;-18.24,-10.24,;-15.93,-11.57,;-12.08,-2.24,;-11.31,-.9,;-9.77,-.9,;-8.74,.24,;-9.14,1.73,;-2,-.39,;-2,-1.92,)|

BDBM438830

Cn1c2CCN(CCCCC(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM438831

CN(C)C(=O)CCCCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM438832

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)[C@H]2CC[C@](C)(CC2)C(O)=O)c1Cl |r,wU:53.60,wD:50.56,53.64,(-8.12,2.79,;-7.72,1.3,;-8.75,.15,;-10.29,.15,;-11.06,-1.18,;-10.29,-2.51,;-11.06,-3.85,;-12.6,-3.85,;-13.37,-5.18,;-12.6,-6.51,;-13.37,-7.85,;-14.91,-7.85,;-15.68,-6.51,;-14.91,-5.18,;-14.51,-6.36,;-15.68,-9.18,;-17.22,-9.18,;-14.91,-10.51,;-8.75,-2.51,;-7.98,-1.18,;-6.47,-.86,;-6.31,.67,;-4.98,1.44,;-4.98,2.98,;-3.65,.67,;-2.31,1.44,;-2.31,2.98,;-.98,3.75,;.35,2.98,;.35,1.44,;-.98,.67,;-.98,-.87,;1.69,.67,;1.69,-.87,;3.02,-1.64,;4.36,-.87,;4.36,.67,;5.69,1.44,;7.02,.67,;7.02,-.87,;8.36,1.44,;8.52,2.97,;10.02,3.29,;10.79,4.63,;12.33,4.63,;13.1,3.29,;12.33,1.96,;10.79,1.96,;9.76,.82,;10.16,-.67,;13.1,5.96,;14.64,5.96,;15.41,7.3,;14.64,8.63,;14.25,10.12,;13.1,8.63,;12.33,7.3,;16.13,9.03,;16.53,10.51,;17.22,7.94,;3.02,1.44,;3.02,2.98,)|

BDBM438833

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)[C@H]2CC[C@@](C)(CC2)C(O)=O)c1Cl |r,wU:53.64,wD:50.56,53.60,(-8.12,2.79,;-7.72,1.3,;-8.75,.15,;-10.29,.15,;-11.06,-1.18,;-10.29,-2.51,;-11.06,-3.85,;-12.6,-3.85,;-13.37,-5.18,;-12.6,-6.51,;-13.37,-7.85,;-14.91,-7.85,;-15.68,-6.51,;-14.91,-5.18,;-14.51,-6.36,;-15.68,-9.18,;-17.22,-9.18,;-14.91,-10.51,;-8.75,-2.51,;-7.98,-1.18,;-6.47,-.86,;-6.31,.67,;-4.98,1.44,;-4.98,2.98,;-3.65,.67,;-2.31,1.44,;-2.31,2.98,;-.98,3.75,;.35,2.98,;.35,1.44,;-.98,.67,;-.98,-.87,;1.69,.67,;1.69,-.87,;3.02,-1.64,;4.36,-.87,;4.36,.67,;5.69,1.44,;7.02,.67,;7.02,-.87,;8.36,1.44,;8.52,2.97,;10.02,3.29,;10.79,4.63,;12.33,4.63,;13.1,3.29,;12.33,1.96,;10.79,1.96,;9.76,.82,;10.16,-.67,;13.1,5.96,;14.64,5.96,;15.41,7.3,;14.64,8.63,;14.25,10.12,;13.1,8.63,;12.33,7.3,;16.13,9.03,;16.53,10.51,;17.22,7.94,;3.02,1.44,;3.02,2.98,)|

BDBM446448

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CCC(CC5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@@H](O)C3)cc2n1 |r|

BDBM446449

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CCC(CC5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@@](C)(O)C3)cc2n1 |r|

BDBM446450

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CCC(CC5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@](C)(O)C3)cc2n1 |r|

BDBM446451

C[C@@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CCC(CC6)C(O)=O)cc(C#N)c5o4)c3C)nc(C)nc2c1 |r|

BDBM446452

C[C@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CCC(CC6)C(O)=O)cc(C#N)c5o4)c3C)nc(C)nc2c1 |r|

BDBM446453

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@@H](O)C3)cc2n1 |r|

BDBM446454

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@@](C)(O)C3)cc2n1 |r|

BDBM446455

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@](C)(O)C3)cc2n1 |r|

BDBM446456

C[C@@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@H](C6)C(O)=O)cc(C#N)c5o4)c3C)nc(C)nc2c1 |r|

BDBM446457

C[C@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@H](C6)C(O)=O)cc(C#N)c5o4)c3C)nc(C)nc2c1 |r|

BDBM446458

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@@H](O)C3)cc2n1 |r|

BDBM446459

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@@](C)(O)C3)cc2n1 |r|

BDBM446460

Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@](C)(O)C3)cc2n1 |r|

BDBM446461

C[C@@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nc(C)nc2c1 |r|

BDBM446462

C[C@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nc(C)nc2c1 |r|

BDBM446463

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446464

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446465

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446469

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446470

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446471

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CCC(C)(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446472

CN(C)C(=O)C1CCN(Cc2cc(C#N)c3oc(nc3c2)-c2cccc(c2C)-c2cccc(Nc3nc(nc4cc(CN5CC[C@@H](O)C5)cnc34)C(F)F)c2C)CC1 |r|

BDBM446473

CNC(=O)C1CCN(Cc2cc(C#N)c3oc(nc3c2)-c2cccc(c2C)-c2cccc(Nc3nc(nc4cc(CN5CC[C@@H](O)C5)cnc34)C(F)F)c2C)CC1 |r|

BDBM446474

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(=O)NCCC(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446475

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C2CC2)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446476

Cc1c(Nc2nc(N)nc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446477

Cc1c(Nc2nc(nc3cc(CN4CC[C@@](C)(O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446478

Cc1c(Nc2nc(nc3cc(CN4CC[C@](C)(O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446479

Cc1c(Nc2nc(CO)nc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM446481

Cc1c(Nc2nc(cc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM451862

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1F)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM451863

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1F)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM451864

COC1CN(Cc2ncc(nc2OC)-c2cccc(c2F)-c2cccc(c2Cl)-c2cnc(CN3CC(C3)OC)c(OC)n2)C1

BDBM451865

COc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1F)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM451866

COc1nc(cnc1CNCCO)-c1cccc(c1F)-c1cccc(c1Cl)-c1cnc(CNCCO)c(OC)n1

BDBM451867

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1F)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451868

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC23CC(C2)(C3)C#N)c(OC)n1 |r|

BDBM451869

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC23CC(C2)(C3)OC)c(OC)n1 |r|

BDBM451870

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(C2)C#N)c(OC)n1 |r|

BDBM451871

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)C#N)c(OC)n1 |r|

BDBM451872

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2COC[C@H]2O)c(OC)n1 |r|

BDBM451873

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC23CC(C2)C3)c(OC)n1 |r|

BDBM451874

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)C(N)=O)c(OC)n1 |r|

BDBM451875

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)N2CCCC2=O)c(OC)n1 |r|

BDBM451876

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC23CC(C2)(C3)C(F)(F)F)c(OC)n1 |r|

BDBM451877

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(O)C2)c(OC)n1 |r|

BDBM451878

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCCN2C(C)=O)c(OC)n1 |r|

BDBM451879

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCCN2C(C)=O)c(OC)n1 |r|

BDBM451880

CNC(=O)[C@@H]1CCCN1Cc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451881

CNC(=O)[C@H]1CCCN1Cc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451882

COC[C@H]1CCCN1Cc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451883

COC[C@@H]1CCCN1Cc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451884

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC[C@@H]2CO)c(OC)n1 |r|

BDBM451885

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC[C@H]2CO)c(OC)n1 |r|

BDBM451886

COc1nc(cnc1CNCCOC(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451887

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2cnn(CCO)c2)c(OC)n1 |r|

BDBM451888

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2ccn(C)n2)c(OC)n1 |r|

BDBM451889

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2nc[nH]n2)c(OC)n1 |r|

BDBM451890

COc1nc(cnc1CNCc1nc(C)n[nH]1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2nc(C)n[nH]2)c(OC)n1

BDBM451891

COc1nc(cnc1CNCc1ccn(C)n1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2ccn(C)n2)c(OC)n1

BDBM451892

CCn1cc(CNCc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNCc3cnn(CC)c3)c(OC)n2)cn1

BDBM451893

CCn1cc(CNCc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nn1 |r|

BDBM451894

COc1nc(cnc1CNCCc1cnn[nH]1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451895

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2ccnn2C)c(OC)n1 |r|

BDBM451896

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2c[nH]nn2)c(OC)n1 |r|

BDBM451897

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@@H](N)CCC2=O)c(OC)n1 |r|

BDBM451898

COc1nc(cnc1CNCCNc1ccc(cc1)[N+]([O-])=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451899

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(CO)c2nn[nH]n2)c(OC)n1 |r|

BDBM451900

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CCNC2=O)c(OC)n1 |r|

BDBM451901

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@@H](F)C[C@H]2CO)c(OC)n1 |r|

BDBM451902

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCNC(=O)C2)c(OC)n1 |r|

BDBM451903

COc1nc(cnc1CNCCS(O)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451904

COc1nc(cnc1CNCCS(N)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451905

COc1nc(cnc1CNCCNC(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451906

COc1nc(cnc1CNCCC(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451907

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)C)c(OC)n1 |r|

BDBM451908

COc1nc(cnc1CNCC(O)C(F)(F)F)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451909

CCN(CCc1cn[nH]c1)Cc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451910

COc1nc(cnc1CNCCc1cn[nH]c1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451911

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)O3)c(OC)n1 |r|

BDBM451912

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)CC(N)=O)c(OC)n1 |r|

BDBM451913

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3CC3(CO)C2)c(OC)n1 |r|

BDBM451914

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3CC2(CO)C3)c(OC)n1 |r,wU:11.11,(-5.61,-5,;-4.28,-4.23,;-4.28,-2.69,;-2.95,-1.93,;-2.95,-.38,;-4.28,.38,;-5.61,-.38,;-5.61,-1.93,;-6.95,-2.69,;-8.28,-1.93,;-9.61,-2.69,;-10.95,-1.93,;-11.11,-.39,;-12.61,-.07,;-13.38,-1.41,;-14.92,-1.57,;-12.35,-2.55,;-1.61,.38,;-1.61,1.93,;-.28,2.69,;1.06,1.93,;1.06,.38,;-.28,-.38,;-.28,-1.93,;2.39,-.38,;2.39,-1.93,;3.72,-2.69,;5.06,-1.93,;5.06,-.38,;3.72,.38,;3.72,1.93,;6.39,.38,;7.72,-.38,;9.06,.38,;9.06,1.93,;10.39,2.69,;11.72,1.93,;11.89,.39,;13.39,.07,;14.16,1.41,;13.13,2.55,;13.45,4.06,;14.92,4.53,;12.73,1.06,;7.72,2.69,;7.72,4.23,;6.39,5,;6.39,1.93,)|

BDBM451915

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCC[C@@H]2O)c(OC)n1 |r|

BDBM451916

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCCCO2)c(OC)n1 |r|

BDBM451917

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCC(O2)C(N)=O)c(OC)n1 |r|

BDBM451918

CNc1nc(cnc1CNC[C@H]1C[C@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2C[C@H](O)C2)c(NC)n1 |r,wU:11.11,37.40,wD:39.43,13.14,(-4.67,-5,;-6,-4.23,;-6,-2.69,;-4.67,-1.93,;-4.67,-.38,;-6,.38,;-7.34,-.38,;-7.34,-1.93,;-8.67,-2.69,;-10,-1.93,;-11.34,-2.69,;-12.67,-1.93,;-14.16,-2.32,;-14.56,-.84,;-15.89,-.07,;-13.07,-.44,;-3.33,.38,;-3.33,1.93,;-2,2.69,;-.67,1.93,;-.67,.38,;-2,-.38,;-2,-1.93,;.67,-.38,;.67,-1.93,;2,-2.69,;3.33,-1.93,;3.33,-.38,;2,.38,;2,1.93,;4.67,.38,;6,-.38,;7.34,.38,;7.34,1.93,;8.67,2.69,;10,1.93,;11.34,2.69,;12.67,1.93,;14.16,2.32,;14.56,.84,;15.89,.07,;13.07,.44,;6,2.69,;6,4.23,;4.67,5,;4.67,1.93,)|

BDBM451919

CNc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN)c(NC)n1

BDBM451920

CNc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM451921

CNc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM451922

CNc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM451923

CNc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM451924

CNc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451925

CCNc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(NCC)n1

BDBM451926

CCNc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(NCC)n1

BDBM451927

CCNc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(NCC)n1

BDBM451928

CCNc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(NCC)n1

BDBM451929

CNc1nc(cnc1CN1CC(F)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(F)C2)c(NC)n1

BDBM451930

CNc1nc(cnc1CN1CCCC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC2)c(NC)n1

BDBM451931

CNc1nc(cnc1CN(C)C)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)C)c(NC)n1

BDBM451932

CNc1nc(cnc1CN1CCC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC2)c(NC)n1

BDBM451933

CNCc1ncc(nc1NC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC2)c(NC)n1

BDBM451934

CNCc1ncc(nc1NC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC)c(NC)n1

BDBM451935

CNc1nc(cnc1CN1CC(C1)OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)OC)c(NC)n1

BDBM451936

CNc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(NC)n1

BDBM451937

CNc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(NC)n1

BDBM451938

CNc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(NC)n1

BDBM451939

CNc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(NC)n1

BDBM451940

CNc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(NC)n1 |r|

BDBM451941

OC1CN(Cc2cnc(cn2)-c2cccc(c2Cl)-c2cccc(-c3cnc(CN4CC(O)C4)cn3)c2Cl)C1

BDBM451942

CCc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(-c2cnc(CN3CC(O)C3)c(CC)n2)c1Cl

BDBM451943

CCc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(CC)n1

BDBM451944

CCc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(CC)n1

BDBM451945

CCc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(CC)n1 |r|

BDBM451946

COc1nc(cnc1CNC12CC(C1)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC23CC(C2)C3)c(OC)n1

BDBM451947

COC1CN(Cc2ncc(nc2SC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CN3CC(C3)OC)c(SC)n2)C1

BDBM451948

CSc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(SC)n1

BDBM451949

CSc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(SC)n1

BDBM451950

CSc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(SC)n1

BDBM451951

CSc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(SC)n1 |r|

BDBM451952

COC1CN(Cc2ncc(nc2C)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CN3CC(C3)OC)c(C)n2)C1

BDBM451953

Cc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(-c2cnc(CN3CC(O)C3)c(C)n2)c1Cl

BDBM451954

Cc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(C)n1

BDBM451955

Cc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(C)n1

BDBM451956

Cc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(C)n1 |r|

BDBM451957

COC1CN(Cc2ncc(nc2N(C)C)-c2cccc(c2Cl)-c2cccc(-c3cnc(CN4CC(C4)OC)c(n3)N(C)C)c2Cl)C1

BDBM451958

COC1CN(Cc2ncc(nc2Cl)-c2cccc(c2Cl)-c2cccc(-c3cnc(CN4CC(C4)OC)c(n3)N(C)C)c2Cl)C1

BDBM451959

CN(C)c1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(-c2cnc(CN3CC(O)C3)c(n2)N(C)C)c1Cl

BDBM451960

CN(C)c1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(-c2cnc(CN3CC(O)C3)c(Cl)n2)c1Cl

BDBM451961

CN(C)c1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(n1)N(C)C

BDBM451962

CN(C)c1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(Cl)n1

BDBM451963

CN(C)c1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(n1)N(C)C

BDBM451964

CN(C)c1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(Cl)n1

BDBM451965

CN(C)c1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(n1)N(C)C |r|

BDBM451966

CN(C)c1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(Cl)n1 |r|

BDBM451967

COC1CN(Cc2ncc(nc2Cl)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CN3CC(C3)OC)c(Cl)n2)C1

BDBM451968

OC1CN(Cc2ncc(nc2Cl)-c2cccc(c2Cl)-c2cccc(-c3cnc(CN4CC(O)C4)c(Cl)n3)c2Cl)C1

BDBM451969

Clc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(Cl)n1

BDBM451970

Clc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(Cl)n1

BDBM451971

Clc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(Cl)n1 |r|

BDBM451972

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Br)-c1cccc(c1Br)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM451973

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Br)-c1cccc(c1Br)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451974

COc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(C2=NCCN2)c(OC)n1 |t:41|

BDBM451975

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(C2=NCCN2)c(OC)n1 |t:41|

BDBM451976

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(C2=NCCN2)c(OC)n1 |t:36|

BDBM451977

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(C2=NCCN2)c(OC)n1 |r,t:39|

BDBM451978

COc1nc(cnc1CN1CC(F)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(F)C2)c(OC)n1

BDBM451979

COc1nc(cnc1C1=NCC(F)(F)CN1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCC(F)(F)CN2)c(OC)n1 |t:9,38|

BDBM451980

COc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM451981

COc1nc(cnc1C1=NC[C@H](C)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NC[C@H](C)N2)c(OC)n1 |r,t:9,36|

BDBM451982

COc1cc(ccc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN)c(OC)n1

BDBM451983

COc1cc(ccc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM451984

COc1cc(ccc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM451985

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451986

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451987

COc1nc(cnc1C1=NCC(C)(C)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCC(C)(C)N2)c(OC)n1 |t:9,37|

BDBM451988

COc1nc(cnc1C1=NCC(O)CN1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCC(O)CN2)c(OC)n1 |t:9,37|

BDBM451989

COc1nc(cnc1C1=NC[C@@H](C)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NC[C@@H](C)N2)c(OC)n1 |r,t:9,36|

BDBM451990

COc1nc(cnc1CN1CC[C@@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](O)C2)c(OC)n1 |r|

BDBM451991

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM451992

COc1nc(cnc1CN1CC[C@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](O)C2)c(OC)n1 |r|

BDBM451993

COc1nc(cnc1C1=NC[C@H](CO)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NC[C@H](CO)N2)c(OC)n1 |r,t:9,37|

BDBM451994

COc1nc(cnc1C1=NC[C@@H](CO)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NC[C@@H](CO)N2)c(OC)n1 |r,t:9,37|

BDBM451995

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN)c(OC)n1

BDBM451996

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM451997

COc1nc(cnc1CNC[C@@H](O)CC(O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H](O)CC(O)=O)c(OC)n1 |r|

BDBM451998

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM451999

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452000

COc1nc(cnc1CNCCO)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCCO)c(OC)n1

BDBM452001

COc1nc(cnc1C1=NCCN1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCCN2)c(OC)n1 |t:9,35|

BDBM452002

COc1nc(cnc1CN1CC[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@](C)(O)C2)c(OC)n1 |r|

BDBM452003

COc1nc(cnc1CN[C@@H]1CCOC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCOC2)c(OC)n1 |r|

BDBM452004

COc1nc(cnc1CN[C@H]1CCOC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CCOC2)c(OC)n1 |r|

BDBM452005

COc1nc(cnc1CN1CC(CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(CO)C2)c(OC)n1

BDBM452006

COc1nc(cnc1CN1CCC(C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C)(O)C2)c(OC)n1

BDBM452007

COc1nc(cnc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(O)C2)c(OC)n1

BDBM452008

COc1nc(cnc1CN1CC(C)(CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(CO)C2)c(OC)n1

BDBM452009

COc1nc(cnc1CN[C@H]1C[C@H](CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H](CO)C2)c(OC)n1 |r,wU:10.10,36.39,wD:38.42,12.13,(-4.67,-4.78,;-6,-4.01,;-6,-2.47,;-4.67,-1.7,;-4.67,-.16,;-6,.61,;-7.34,-.16,;-7.34,-1.7,;-8.67,-2.47,;-10,-1.7,;-11.34,-2.47,;-11.73,-3.96,;-13.22,-3.56,;-14.56,-4.33,;-15.89,-3.56,;-12.82,-2.07,;-3.33,.61,;-3.33,2.15,;-2,2.92,;-.67,2.15,;-.67,.61,;-2,-.16,;-2,-1.7,;.67,-.16,;.67,-1.7,;2,-2.47,;3.33,-1.7,;3.33,-.16,;2,.61,;2,2.15,;4.67,.61,;4.67,2.15,;6,2.92,;7.34,2.15,;8.67,2.92,;10,2.15,;11.34,2.92,;11.73,4.41,;13.22,4.01,;14.56,4.78,;15.89,4.01,;12.82,2.52,;7.34,.61,;8.67,-.16,;8.67,-1.7,;6,-.16,)|

BDBM452010

COc1nc(cnc1CN[C@@H]1C[C@H](CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2C[C@H](CO)C2)c(OC)n1 |r,wU:10.10,36.39,38.42,12.13,(-5.33,-4.24,;-6.67,-3.47,;-6.67,-1.93,;-5.33,-1.16,;-5.33,.38,;-6.67,1.15,;-8,.38,;-8,-1.16,;-9.34,-1.93,;-10.67,-1.16,;-12,-1.93,;-13.49,-1.53,;-13.89,-3.01,;-15.22,-3.78,;-15.22,-5.32,;-12.4,-3.41,;-4,1.15,;-4,2.69,;-2.67,3.46,;-1.33,2.69,;-1.33,1.15,;-2.67,.38,;-2.67,-1.16,;,.38,;,-1.16,;1.33,-1.93,;2.67,-1.16,;2.67,.38,;1.33,1.15,;1.33,2.69,;4,1.15,;4,2.69,;5.33,3.46,;6.67,2.69,;8,3.46,;9.34,2.69,;10.67,3.46,;12.16,3.07,;12.56,4.55,;13.89,5.32,;15.22,4.55,;11.07,4.95,;6.67,1.15,;8,.38,;8,-1.16,;5.33,.38,)|

BDBM452011

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(CN2CC3(C2)CCC(=O)N3)c(c1)C#N |r|

BDBM452012

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(CNC[C@@H]2CCC(=O)N2)c(c1)C#N |r|

BDBM452013

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(CN2CC(O)C2)c(c1)C#N |r|

BDBM452014

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(CN2CC(C)(CO)C2)c(c1)C#N |r|

BDBM452015

COc1nc(ccc1CNCc1ccc2[nH]c(C)cc2c1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452016

COc1nc(ccc1CN1CC(C)(CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452017

COc1nc(ccc1CN1CC(CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452018

COc1nc(ccc1CN1CCC(C)(O)CC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452019

COc1nc(ccc1CN1CC[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452020

COc1nc(ccc1CN1CCC(CO)CC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452021

COc1nc(ccc1CNCc1nc(=O)o[nH]1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452022

COc1nc(ccc1CNC1CCOCC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452023

COc1nc(ccc1CN1CCC(CC1)C(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452024

COc1nc(ccc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452025

COc1nc(ccc1CN[C@@H]1COC[C@H]1O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452026

COc1nc(ccc1CN[C@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452027

COc1nc(ccc1CN[C@@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452028

COc1nc(ccc1CN1CC2(C1)CNC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452029

COc1nc(ccc1CN[C@H]1CCNC1=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452030

COc1nc(ccc1CN[C@@H]1CCOC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452031

COc1nc(ccc1CN[C@H]1CCOC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452032

COc1nc(cnc1CNC[C@@H]1C[C@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r,wU:37.40,13.14,11.11,(9.05,-1.93,;9.05,-.38,;7.71,.38,;6.38,-.38,;5.05,.38,;5.05,1.93,;6.38,2.69,;7.71,1.93,;9.05,2.69,;10.38,1.93,;11.72,2.69,;13.05,1.93,;13.45,.44,;14.93,.84,;16.27,.07,;14.54,2.32,;3.71,-.38,;3.71,-1.93,;2.38,-2.69,;1.05,-1.93,;1.05,-.38,;2.38,.38,;2.38,1.93,;-.29,.38,;-.29,1.93,;-1.62,2.69,;-2.96,1.93,;-2.96,.38,;-1.62,-.38,;-1.62,-1.93,;-4.29,-.38,;-4.29,-1.93,;-5.62,-2.69,;-6.96,-1.93,;-8.29,-2.69,;-9.62,-1.93,;-10.96,-2.69,;-12.29,-1.93,;-12.45,-.39,;-13.96,-.07,;-14.73,-1.41,;-16.27,-1.41,;-13.7,-2.55,;-6.96,-.38,;-8.29,.38,;-8.29,1.93,;-5.62,.38,)|

BDBM452033

COC1CN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452034

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C)(O)C2)c(OC)n1 |r|

BDBM452035

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(CO)C2)c(OC)n1 |r|

BDBM452036

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(CO)C2)c(OC)n1 |r|

BDBM452037

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCC(F)C2)c(OC)n1 |r|

BDBM452038

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2C[C@@H]2F)c(OC)n1 |r|

BDBM452039

COc1nc(cnc1CNCC1CC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452040

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2C[C@@H]2C(F)F)c(OC)n1 |r|

BDBM452041

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(C)(C)C(F)F)c(OC)n1 |r|

BDBM452042

COc1nc(cnc1CNCC(F)F)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452043

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)OC(F)F)c(OC)n1 |r|

BDBM452044

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CC2)c(OC)n1 |r|

BDBM452045

COCC1(CCC1)NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452047

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H]3C[C@H]3[C@H]2CO)c(OC)n1 |r|

BDBM452048

COC(=O)NC1CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452049

COc1nc(cnc1CNCC1CN(C1)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CN(C2)C(C)=O)c(OC)n1

BDBM452050

COc1nc(cnc1CNC1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM452051

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CN(C2)C(C)=O)c(OC)n1 |r|

BDBM452052

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1 |r|

BDBM452053

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(CNC(=O)C3)C2)c(OC)n1 |r|

BDBM452054

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCN(C2)C(C)=O)c(OC)n1 |r|

BDBM452055

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CC[C@@H](CC2)NC(C)=O)c(OC)n1 |r,wU:11.11,40.47,wD:37.40,(-9.45,-.38,;-9.45,-1.92,;-8.12,-2.69,;-6.78,-1.92,;-5.45,-2.69,;-5.45,-4.23,;-6.78,-5,;-8.12,-4.23,;-9.45,-5,;-10.78,-4.23,;-12.12,-5,;-13.45,-4.23,;-14.86,-4.86,;-15.89,-3.72,;-15.12,-2.38,;-15.75,-.98,;-13.61,-2.7,;-4.12,-1.92,;-4.12,-.38,;-2.78,.39,;-1.45,-.38,;-1.45,-1.92,;-2.78,-2.69,;-2.78,-4.23,;-.11,-2.69,;-.11,-4.23,;1.22,-5,;2.55,-4.23,;2.55,-2.69,;1.22,-1.92,;1.22,-.38,;3.89,-1.92,;3.89,-.38,;5.22,.39,;6.55,-.38,;7.89,.39,;9.22,-.38,;10.55,.38,;11.89,-.39,;13.22,.38,;13.22,1.92,;11.89,2.7,;10.55,1.92,;14.56,2.69,;14.56,4.23,;13.22,5,;15.89,5,;6.55,-1.92,;7.89,-2.69,;7.89,-4.23,;5.22,-2.69,)|

BDBM452056

COc1nc(cnc1CNCC1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452057

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(CCC(=O)N3)C2)c(OC)n1 |r|

BDBM452058

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](C2)NC(C)=O)c(OC)n1 |r|

BDBM452059

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CNC(=O)C2)c(OC)n1 |r|

BDBM452060

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CNC(=O)C2)c(OC)n1 |r|

BDBM452061

COc1nc(cnc1CNCCc1ncc[nH]1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452062

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCC3(CNC(=O)C3)C2)c(OC)n1 |r|

BDBM452063

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(CCC(=O)N3)CC2)c(OC)n1 |r|

BDBM452064

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](C2)NC(C)=O)c(OC)n1 |r|

BDBM452065

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCCN(C2)C(C)=O)c(OC)n1 |r|

BDBM452066

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCN(CC2)C(C)=O)c(OC)n1 |r|

BDBM452067

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)N3)c(OC)n1 |r|

BDBM452068

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CC3(C2)CN(C3)C(C)=O)c(OC)n1 |r|

BDBM452070

COc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM452071

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(C)COC(=O)N2)c(OC)n1 |r|

BDBM452072

COc1nc(cnc1CNCCN1CCNC1=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452073

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCc3cn[nH]c3C2)c(OC)n1 |r|

BDBM452074

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(CCC2)C#N)c(OC)n1 |r|

BDBM452075

COc1nc(cnc1CNCCn1ccc(C)n1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452076

COC[C@@H]1CC[C@H]1NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452077

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H]3CC[C@@H](O)[C@H]23)c(OC)n1 |r|

BDBM452078

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CC(CC(N)=O)C2)c(OC)n1 |r,wD:11.11,(4.96,-5,;6.29,-4.23,;6.29,-2.69,;4.96,-1.93,;4.96,-.38,;6.29,.38,;7.63,-.38,;7.63,-1.93,;8.96,-2.69,;10.29,-1.92,;11.63,-2.69,;12.96,-1.92,;13.12,-.39,;14.63,-.07,;15.4,-1.41,;16.93,-1.57,;14.37,-2.55,;3.63,.38,;3.63,1.93,;2.29,2.69,;.96,1.93,;.96,.38,;2.29,-.38,;2.29,-1.93,;-.37,-.38,;-.37,-1.93,;-1.71,-2.69,;-3.04,-1.93,;-3.04,-.38,;-1.71,.38,;-1.71,1.93,;-4.38,.38,;-5.71,-.38,;-7.04,.38,;-7.04,1.93,;-8.38,2.69,;-9.71,1.93,;-11.04,2.69,;-11.44,4.18,;-12.93,3.78,;-14.26,4.55,;-15.6,3.78,;-16.93,4.55,;-15.6,2.24,;-12.53,2.3,;-5.71,2.69,;-5.71,4.23,;-4.38,5,;-4.38,1.93,)|

BDBM452079

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(CC2)S(C)(=O)=O)c(OC)n1 |r|

BDBM452080

COc1nc(cnc1CNC[C@@H]1C[C@H]1c1cccnc1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452081

COc1nc(cnc1CNCC1CC1CC#N)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452082

COC[C@H]1C[C@H](C1)NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r,wU:5.7,3.2,wD:38.41,(-16.93,4.55,;-15.6,3.78,;-14.26,4.55,;-12.93,3.78,;-11.44,4.18,;-11.04,2.69,;-12.53,2.3,;-9.71,1.93,;-8.38,2.69,;-7.04,1.93,;-7.04,.38,;-5.71,-.38,;-4.38,.38,;-4.38,1.93,;-5.71,2.69,;-5.71,4.23,;-4.38,5,;-3.04,-.38,;-3.04,-1.93,;-1.71,-2.69,;-.37,-1.93,;-.37,-.38,;-1.71,.38,;-1.71,1.93,;.96,.38,;.96,1.93,;2.29,2.69,;3.63,1.93,;3.63,.38,;2.29,-.38,;2.29,-1.93,;4.96,-.38,;6.29,.38,;7.63,-.38,;7.63,-1.93,;8.96,-2.69,;10.29,-1.92,;11.63,-2.69,;12.96,-1.92,;13.12,-.39,;14.63,-.07,;15.4,-1.41,;16.93,-1.57,;14.37,-2.55,;6.29,-2.69,;6.29,-4.23,;4.96,-5,;4.96,-1.93,)|

BDBM452083

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCC(C2)S(C)=O)c(OC)n1 |r|

BDBM452084

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCOC[C@H]2C)c(OC)n1 |r|

BDBM452085

CO[C@H]1C[C@@H](CO)N(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452086

COCCC1CN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452087

CC[C@@H]1OCC[C@H]1NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452088

COc1nc(cnc1CNCC1CCN(C1)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452089

CO[C@@H]1C[C@H](CNCc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r,wU:4.4,2.1,wD:37.39,(-16.93,.84,;-15.6,.07,;-14.26,.84,;-12.78,.44,;-12.38,1.93,;-11.04,2.69,;-9.71,1.93,;-8.38,2.69,;-7.04,1.93,;-7.04,.38,;-5.71,-.38,;-4.38,.38,;-4.38,1.93,;-5.71,2.69,;-5.71,4.23,;-4.38,5,;-3.04,-.38,;-3.04,-1.93,;-1.71,-2.69,;-.37,-1.93,;-.37,-.38,;-1.71,.38,;-1.71,1.93,;.96,.38,;.96,1.93,;2.29,2.69,;3.63,1.93,;3.63,.38,;2.29,-.38,;2.29,-1.93,;4.96,-.38,;6.29,.38,;7.63,-.38,;7.63,-1.93,;8.96,-2.69,;10.29,-1.92,;11.63,-2.69,;12.96,-1.92,;13.12,-.39,;14.63,-.07,;15.4,-1.41,;16.93,-1.57,;14.37,-2.55,;6.29,-2.69,;6.29,-4.23,;4.96,-5,;4.96,-1.93,;-13.87,2.32,)|

BDBM452090

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](C)[C@@H](O)C2)c(OC)n1 |r|

BDBM452091

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@@H]3CCC[C@]3(CO)C2)c(OC)n1 |r|

BDBM452092

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](O)[C@H](C)C2)c(OC)n1 |r|

BDBM452093

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(CCOC3=O)C2)c(OC)n1 |r|

BDBM452094

CCO[C@H]1C[C@@H](C1)NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r,wU:3.2,wD:38.41,5.7,(-16.93,4.55,;-15.6,3.78,;-14.26,4.55,;-12.93,3.78,;-11.44,4.18,;-11.04,2.69,;-12.53,2.3,;-9.71,1.93,;-8.38,2.69,;-7.04,1.93,;-7.04,.38,;-5.71,-.38,;-4.38,.38,;-4.38,1.93,;-5.71,2.69,;-5.71,4.23,;-4.38,5,;-3.04,-.38,;-3.04,-1.93,;-1.71,-2.69,;-.37,-1.93,;-.37,-.38,;-1.71,.38,;-1.71,1.93,;.96,.38,;.96,1.93,;2.29,2.69,;3.63,1.93,;3.63,.38,;2.29,-.38,;2.29,-1.93,;4.96,-.38,;6.29,.38,;7.63,-.38,;7.63,-1.93,;8.96,-2.69,;10.29,-1.92,;11.63,-2.69,;12.96,-1.92,;13.12,-.39,;14.63,-.07,;15.4,-1.41,;16.93,-1.57,;14.37,-2.55,;6.29,-2.69,;6.29,-4.23,;4.96,-5,;4.96,-1.93,)|

BDBM452095

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCOC3)c(OC)n1 |r|

BDBM452096

COc1nc(cnc1CNCCC1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452097

COc1nc(cnc1CNCCC1CCCO1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452098

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(CCO)C2CC2)c(OC)n1 |r|

BDBM452099

COCC(NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1)C1CC1 |r|

BDBM452100

COc1nc(cnc1CN1CC(F)(CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(F)(CO)C2)c(OC)n1

BDBM452101

COc1nc(cnc1CN1CC(O)(CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)(CO)C2)c(OC)n1

BDBM452102

COc1nc(cnc1CN[C@H]1C[C@@](C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@@](C)(O)C2)c(OC)n1 |r,wU:10.10,36.39,38.43,12.14,wD:38.42,12.13,(-8.58,2.01,;-8.58,.47,;-7.25,-.3,;-5.91,.47,;-4.58,-.3,;-4.58,-1.84,;-5.91,-2.61,;-7.25,-1.84,;-8.58,-2.61,;-9.92,-1.84,;-11.25,-2.61,;-12.05,-3.92,;-13.37,-3.12,;-13.77,-4.6,;-14.85,-2.72,;-12.56,-1.8,;-3.25,.47,;-3.25,2.01,;-1.91,2.78,;-.58,2.01,;-.58,.47,;-1.91,-.3,;-1.91,-1.84,;.75,-.3,;.75,-1.84,;2.09,-2.61,;3.42,-1.84,;3.42,-.3,;2.09,.47,;2.09,2.01,;4.76,.47,;4.76,2.01,;6.09,2.78,;7.42,2.01,;8.76,2.78,;10.09,2.01,;11.42,2.78,;12.23,4.1,;13.54,3.29,;14.85,2.49,;14.35,4.6,;12.74,1.98,;7.42,.47,;8.76,-.3,;8.76,-1.84,;6.09,-.3,)|

BDBM452103

COc1nc(cnc1CNC[C@H]1C[C@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2C[C@H](O)C2)c(OC)n1 |r,wU:37.40,11.11,wD:39.43,13.14,(8.67,-1.93,;8.67,-.38,;7.34,.38,;6,-.38,;4.67,.38,;4.67,1.93,;6,2.69,;7.34,1.93,;8.67,2.69,;10,1.93,;11.34,2.69,;12.67,1.93,;14.16,2.32,;14.56,.84,;15.89,.07,;13.07,.44,;3.33,-.38,;3.33,-1.93,;2,-2.69,;.67,-1.93,;.67,-.38,;2,.38,;2,1.93,;-.67,.38,;-.67,1.93,;-2,2.69,;-3.33,1.93,;-3.33,.38,;-2,-.38,;-2,-1.93,;-4.67,-.38,;-4.67,-1.93,;-6,-2.69,;-7.34,-1.93,;-8.67,-2.69,;-10,-1.93,;-11.34,-2.69,;-12.67,-1.93,;-14.16,-2.32,;-14.56,-.84,;-15.89,-.07,;-13.07,-.44,;-7.34,-.38,;-8.67,.38,;-8.67,1.93,;-6,.38,)|

BDBM452104

COc1nc(cnc1CNC[C@@H]1C[C@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2C[C@H](O)C2)c(OC)n1 |r,wU:37.40,11.11,39.43,13.14,(8.67,-1.93,;8.67,-.38,;7.34,.38,;6,-.38,;4.67,.38,;4.67,1.93,;6,2.69,;7.34,1.93,;8.67,2.69,;10,1.93,;11.34,2.69,;12.67,1.93,;13.07,.44,;14.56,.84,;15.89,.07,;14.16,2.32,;3.33,-.38,;3.33,-1.93,;2,-2.69,;.67,-1.93,;.67,-.38,;2,.38,;2,1.93,;-.67,.38,;-.67,1.93,;-2,2.69,;-3.33,1.93,;-3.33,.38,;-2,-.38,;-2,-1.93,;-4.67,-.38,;-4.67,-1.93,;-6,-2.69,;-7.34,-1.93,;-8.67,-2.69,;-10,-1.93,;-11.34,-2.69,;-12.67,-1.93,;-13.07,-.44,;-14.56,-.84,;-15.89,-.07,;-14.16,-2.32,;-7.34,-.38,;-8.67,.38,;-8.67,1.93,;-6,.38,)|

BDBM452105

COc1nc(cnc1CNC[C@@H]1CC(C)(C)C(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CC(C)(C)C(=O)N2)c(OC)n1 |r|

BDBM452106

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CC(C)(C)C(=O)N2)c(OC)n1 |r|

BDBM452107

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2COC(=O)N2)c(OC)n1 |r|

BDBM452108

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(CO)CCF)c(OC)n1 |r|

BDBM452109

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(CO)CF)c(OC)n1 |r|

BDBM452110

COCC(NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1)C(F)(F)F |r|

BDBM452111

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCN[C@@H](C)C2)c(OC)n1 |r|

BDBM452112

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCN[C@H](C)C2)c(OC)n1 |r|

BDBM452113

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(F)(CO)C2)c(OC)n1 |r|

BDBM452114

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)(CO)C2)c(OC)n1 |r|

BDBM452115

COc1nc(cnc1CNC[C@H]1CCN1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452116

COc1nc(cnc1CNCC1CNC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452117

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCN(CC2)C=O)c(OC)n1 |r|

BDBM452118

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H](CO)C(C)C)c(OC)n1 |r|

BDBM452119

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(CCO)CC(F)(F)F)c(OC)n1 |r|

BDBM452120

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCN[C@@H](C2)C2CC2)c(OC)n1 |r|

BDBM452121

CO[C@@H]1CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C[C@@H]1F |r|

BDBM452122

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC(F)(CO)C2)c(OC)n1 |r|

BDBM452123

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CC(C)C(=O)N2)c(OC)n1 |r|

BDBM452124

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@@H](O)C[C@@H](F)C2)c(OC)n1 |r|

BDBM452125

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](O)C[C@@H](F)C2)c(OC)n1 |r|

BDBM452126

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](O)[C@@H](F)C2)c(OC)n1 |r|

BDBM452127

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](O)[C@H](C2)C#N)c(OC)n1 |r|

BDBM452128

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCC(F)(F)C2)c(OC)n1 |r|

BDBM452129

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H]2CO)c(OC)n1 |r|

BDBM452130

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCN(CC2)C2CC2)c(OC)n1 |r|

BDBM452131

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC[C@@H](F)C2)c(OC)n1 |r|

BDBM452132

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC(F)(F)C2)c(OC)n1 |r|

BDBM452133

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC(C2)C(F)F)c(OC)n1 |r|

BDBM452134

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CC3CC3C2)c(OC)n1 |r|

BDBM452135

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@@](C)(O)C2)c(OC)n1 |r,wU:11.11,37.40,39.44,wD:39.43,(-7.7,.64,;-7.7,-.9,;-6.37,-1.67,;-5.04,-.9,;-3.7,-1.67,;-3.7,-3.21,;-5.04,-3.98,;-6.37,-3.21,;-7.7,-3.98,;-9.04,-3.21,;-10.37,-3.98,;-11.71,-3.21,;-11.87,-1.68,;-13.37,-1.36,;-14.14,-2.7,;-15.67,-2.86,;-13.11,-3.84,;-2.37,-.9,;-2.37,.64,;-1.04,1.41,;.3,.64,;.3,-.9,;-1.04,-1.67,;-1.04,-3.21,;1.63,-1.67,;1.63,-3.21,;2.97,-3.98,;4.3,-3.21,;4.3,-1.67,;2.97,-.9,;2.97,.64,;5.63,-.9,;5.63,.64,;6.97,1.41,;8.3,.64,;9.63,1.41,;10.97,.64,;12.3,1.41,;12.7,2.89,;14.19,2.5,;15.67,2.1,;14.59,3.98,;13.79,1.01,;8.3,-.9,;9.63,-1.67,;9.63,-3.21,;6.97,-1.67,)|

BDBM452136

COc1nc(cnc1CNC[C@H]1C[C@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r,wU:37.40,11.11,wD:13.14,(8.86,-1.93,;8.86,-.39,;7.52,.38,;6.19,-.39,;4.86,.38,;4.86,1.92,;6.19,2.69,;7.52,1.92,;8.86,2.69,;10.19,1.92,;11.53,2.7,;12.86,1.93,;14.19,2.7,;14.96,1.36,;16.45,.96,;13.63,.59,;3.52,-.39,;3.52,-1.93,;2.19,-2.7,;.86,-1.93,;.86,-.39,;2.19,.38,;2.19,1.92,;-.48,.38,;-.48,1.92,;-1.81,2.69,;-3.15,1.92,;-3.15,.38,;-1.81,-.39,;-1.81,-1.93,;-4.48,-.39,;-4.48,-1.93,;-5.81,-2.7,;-7.15,-1.93,;-8.48,-2.7,;-9.81,-1.93,;-11.15,-2.7,;-12.48,-1.93,;-12.64,-.39,;-14.15,-.07,;-14.92,-1.41,;-16.45,-1.57,;-13.89,-2.55,;-7.15,-.39,;-8.48,.38,;-8.48,1.92,;-5.81,.38,)|

BDBM452137

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2C[C@H]2CO)c(OC)n1 |r|

BDBM452138

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](O)[C@@H](F)C2)c(OC)n1 |r|

BDBM452139

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](O)[C@@H](F)C2)c(OC)n1 |r|

BDBM452140

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](O)[C@H](F)C2)c(OC)n1 |r|

BDBM452141

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](O)[C@H](F)C2)c(OC)n1 |r|

BDBM452142

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2COC(=O)N2)c(OC)n1 |r|

BDBM452143

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(F)(F)CC2)c(OC)n1 |r|

BDBM452144

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CC(F)C2)c(OC)n1 |r,wD:11.11,(-8.39,1,;-8.39,-.54,;-7.06,-1.31,;-5.73,-.54,;-4.39,-1.31,;-4.39,-2.85,;-5.73,-3.62,;-7.06,-2.85,;-8.39,-3.62,;-9.73,-2.85,;-11.06,-3.62,;-12.39,-2.85,;-13.8,-3.48,;-14.83,-2.34,;-14.06,-1,;-14.69,.4,;-12.56,-1.32,;-3.06,-.54,;-3.06,1,;-1.72,1.77,;-.39,1,;-.39,-.54,;-1.72,-1.31,;-1.72,-2.85,;.94,-1.31,;.94,-2.85,;2.28,-3.62,;3.61,-2.85,;3.61,-1.31,;2.28,-.54,;2.28,1,;4.94,-.54,;4.94,1,;6.28,1.77,;7.61,1,;8.94,1.77,;10.28,1,;11.61,1.77,;13.1,1.37,;13.5,2.85,;14.83,3.62,;12.01,3.25,;7.61,-.54,;8.94,-1.31,;8.94,-2.85,;6.28,-1.31,)|

BDBM452145

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CC(F)(F)C2)c(OC)n1 |r|

BDBM452146

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC(C2)NC(C)=O)c(OC)n1 |r|

BDBM452147

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(O)CCS(=O)(=O)C2)c(OC)n1 |r|

BDBM452148

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H]3CNC(=O)[C@@H]23)c(OC)n1 |r|

BDBM452149

CNC(=O)CNCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452150

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(CC(O)C3)C2)c(OC)n1 |r|

BDBM452151

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(CC2)NC(=O)NC3=O)c(OC)n1 |r|

BDBM452152

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC3(C2)NC(C)=NC3=O)c(OC)n1 |r,c:49|

BDBM452153

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(C2)NC(=O)NC3=O)c(OC)n1 |r|

BDBM452154

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC3(C2)NC(=O)NC3=O)c(OC)n1 |r|

BDBM452155

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(C2)NC(=O)N(C)C3=O)c(OC)n1 |r|

BDBM452156

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCO[C@@H]2C)c(OC)n1 |r|

BDBM452157

COc1nc(cnc1CNC[C@H]1CCOC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452159

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)[C@H]2CCOC2)c(OC)n1 |r|

BDBM452160

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(CC(CO)C3)C2)c(OC)n1 |r,wU:11.11,(-8.87,1.93,;-8.87,.38,;-7.54,-.38,;-6.2,.38,;-4.87,-.38,;-4.87,-1.93,;-6.2,-2.69,;-7.54,-1.93,;-8.87,-2.69,;-10.2,-1.93,;-11.54,-2.69,;-12.87,-1.93,;-13.03,-.39,;-14.54,-.07,;-15.31,-1.41,;-16.84,-1.57,;-14.28,-2.55,;-3.54,.38,;-3.54,1.93,;-2.2,2.69,;-.87,1.93,;-.87,.38,;-2.2,-.38,;-2.2,-1.93,;.46,-.38,;.46,-1.93,;1.8,-2.69,;3.13,-1.93,;3.13,-.38,;1.8,.38,;1.8,1.93,;4.47,.38,;4.47,1.93,;5.8,2.69,;7.13,1.93,;8.47,2.69,;9.8,1.93,;9.96,.39,;11.47,.07,;12.24,1.41,;13.43,.44,;14.4,1.63,;15.94,1.8,;16.84,.55,;13.21,2.6,;11.21,2.55,;7.13,.38,;8.47,-.38,;8.47,-1.93,;5.8,-.38,)|

BDBM452161

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCN2CCOC2)c(OC)n1 |r|

BDBM452162

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](CO)[C@@H](O)C2)c(OC)n1 |r|

BDBM452163

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(CCS3(=O)=O)C2)c(OC)n1 |r|

BDBM452164

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC(N)=O)c(OC)n1 |r|

BDBM452165

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2C)c(OC)n1 |r|

BDBM452166

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H](CO)C(N)=O)c(OC)n1 |r|

BDBM452167

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2cccn(C)c2=O)c(OC)n1 |r|

BDBM452168

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCS(=O)(=O)N2)c(OC)n1 |r|

BDBM452169

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CC(C)(O)C3)c(OC)n1 |r|

BDBM452170

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CC(O)(C3)C(F)(F)F)c(OC)n1 |r|

BDBM452171

COC[C@H]1CCN1Cc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452172

COC[C@@H]1CCN1Cc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452173

COc1nc(cnc1CNCC1CS(=O)(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452174

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H]3CC(=O)N[C@H]3C2)c(OC)n1 |r|

BDBM452175

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)NC(=O)NC3=O)c(OC)n1 |r|

BDBM452176

COc1nc(cnc1CNCC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452177

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc([C@@H](C)N)c(OC)n1 |r|

BDBM452178

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc([C@H](C)N)c(OC)n1 |r|

BDBM452179

COc1nc(cnc1CN[C@@H](C)[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H](C)[C@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452180

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452181

CNc1nc(cnc1CN(C)C[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)C[C@@H]2CCC(=O)N2)c(NC)n1 |r|

BDBM452182

CNc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCC(=O)N2)c(NC)n1 |r|

BDBM452183

COc1nc(cnc1CN[C@@H]1CCN(C1)S(C)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCN(C2)S(C)(=O)=O)c(OC)n1 |r|

BDBM452184

COc1nc(cnc1CN(C)CCO)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)C[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452185

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)CCO)c(OC)n1 |r|

BDBM452186

COc1nc(cnc1CNC[C@H]1NC(=O)[C@@H]2C[C@H]12)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2NC(=O)[C@@H]3C[C@H]23)c(OC)n1 |r|

BDBM452187

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C[C@@H]2CCC(=O)N2)Cc2ccccc2)c(OC)n1 |r|

BDBM452188

COc1nc(cnc1CNC[C@@H]1C[C@@H](C)C(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2C[C@@H](C)C(=O)N2)c(OC)n1 |r|

BDBM452189

COc1nc(cnc1CN(C)C[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)C[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452190

COc1nc(cnc1CN(CC1CC1)C[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(CC2CC2)C[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452191

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(CC2CC2)C[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452192

COc1nc(cnc1CNC[C@@H]1C[C@@H](CC(F)(F)F)C(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2C[C@@H](CC(F)(F)F)C(=O)N2)c(OC)n1 |r|

BDBM452193

COc1nc(cnc1CNC[C@@H]1CC2(CC2)C(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CC3(CC3)C(=O)N2)c(OC)n1 |r|

BDBM452194

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2[C@@H](C)COC[C@@H]2C)c(OC)n1 |r|

BDBM452195

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCN(C2)C2COC2)c(OC)n1 |r|

BDBM452196

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCOC[C@H]2O)c(OC)n1 |r|

BDBM452197

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CCOC[C@@H]2O)c(OC)n1 |r|

BDBM452198

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2COCC[C@@H]2O)c(OC)n1 |r|

BDBM452199

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2ccc(s2)S(N)(=O)=O)c(OC)n1 |r|

BDBM452200

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2ncccc2O)c(OC)n1 |r|

BDBM452201

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2COCC[C@H]2O)c(OC)n1 |r|

BDBM452202

COCCNCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452203

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2C[C@H](CO)C2)c(OC)n1 |r,wU:11.11,37.40,39.43,(-8.29,1,;-8.29,-.54,;-6.96,-1.31,;-5.63,-.54,;-4.29,-1.31,;-4.29,-2.85,;-5.63,-3.62,;-6.96,-2.85,;-8.29,-3.62,;-9.63,-2.85,;-10.96,-3.62,;-12.3,-2.85,;-12.46,-1.32,;-13.96,-1,;-14.73,-2.34,;-16.26,-2.5,;-13.7,-3.48,;-2.96,-.54,;-2.96,1,;-1.63,1.77,;-.29,1,;-.29,-.54,;-1.63,-1.31,;-1.63,-2.85,;1.04,-1.31,;1.04,-2.85,;2.38,-3.62,;3.71,-2.85,;3.71,-1.31,;2.38,-.54,;2.38,1,;5.04,-.54,;5.04,1,;6.38,1.77,;7.71,1,;9.04,1.77,;10.38,1,;11.71,1.77,;13.2,1.37,;13.6,2.85,;14.93,3.62,;16.26,2.85,;12.11,3.25,;7.71,-.54,;9.04,-1.31,;9.04,-2.85,;6.38,-1.31,)|

BDBM452204

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H](O)C2)c(OC)n1 |r,wU:11.11,37.40,wD:39.43,(-7.63,1,;-7.63,-.54,;-6.29,-1.31,;-4.96,-.54,;-3.63,-1.31,;-3.63,-2.85,;-4.96,-3.62,;-6.29,-2.85,;-7.63,-3.62,;-8.96,-2.85,;-10.29,-3.62,;-11.63,-2.85,;-11.79,-1.32,;-13.3,-1,;-14.07,-2.34,;-15.6,-2.5,;-13.04,-3.48,;-2.29,-.54,;-2.29,1,;-.96,1.77,;.37,1,;.37,-.54,;-.96,-1.31,;-.96,-2.85,;1.71,-1.31,;1.71,-2.85,;3.04,-3.62,;4.38,-2.85,;4.38,-1.31,;3.04,-.54,;3.04,1,;5.71,-.54,;5.71,1,;7.04,1.77,;8.38,1,;9.71,1.77,;11.04,1,;12.38,1.77,;12.78,3.25,;14.26,2.85,;15.6,3.62,;13.87,1.37,;8.38,-.54,;9.71,-1.31,;9.71,-2.85,;7.04,-1.31,)|

BDBM452205

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2C[C@H](O)C2)c(OC)n1 |r,wU:11.11,37.40,39.43,(-7.63,1,;-7.63,-.54,;-6.29,-1.31,;-4.96,-.54,;-3.63,-1.31,;-3.63,-2.85,;-4.96,-3.62,;-6.29,-2.85,;-7.63,-3.62,;-8.96,-2.85,;-10.29,-3.62,;-11.63,-2.85,;-11.79,-1.32,;-13.3,-1,;-14.07,-2.34,;-15.6,-2.5,;-13.04,-3.48,;-2.29,-.54,;-2.29,1,;-.96,1.77,;.37,1,;.37,-.54,;-.96,-1.31,;-.96,-2.85,;1.71,-1.31,;1.71,-2.85,;3.04,-3.62,;4.38,-2.85,;4.38,-1.31,;3.04,-.54,;3.04,1,;5.71,-.54,;5.71,1,;7.04,1.77,;8.38,1,;9.71,1.77,;11.04,1,;12.38,1.77,;13.87,1.37,;14.26,2.85,;15.6,3.62,;12.78,3.25,;8.38,-.54,;9.71,-1.31,;9.71,-2.85,;7.04,-1.31,)|

BDBM452206

COc1nc(cnc1CNC[C@H](C)O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452207

COc1nc(cnc1CNC[C@@H](C)O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452208

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H](C)CO)c(OC)n1 |r|

BDBM452209

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H](C)CO)c(OC)n1 |r|

BDBM452210

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)N2CC(O)C2)c(OC)n1 |r|

BDBM452211

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)c2ccccn2)c(OC)n1 |r|

BDBM452212

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)c2ccccc2)c(OC)n1 |r|

BDBM452213

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)N2CCOCC2)c(OC)n1 |r|

BDBM452214

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(Cn2c(C)ccc2C)c(OC)n1 |r|

BDBM452215

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CC[C@H](O)C2)c(OC)n1 |r|

BDBM452216

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CC[C@@H](O)C2)c(OC)n1 |r|

BDBM452217

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CC[C@H](O)C2)c(OC)n1 |r|

BDBM452218

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CC[C@@H](O)C2)c(OC)n1 |r|

BDBM452219

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@@H](C2)S(C)(=O)=O)c(OC)n1 |r,wU:11.11,39.45,wD:37.40,(-8.29,.33,;-8.29,-1.21,;-6.96,-1.98,;-5.63,-1.21,;-4.29,-1.98,;-4.29,-3.52,;-5.63,-4.29,;-6.96,-3.52,;-8.29,-4.29,;-9.63,-3.52,;-10.96,-4.29,;-12.3,-3.52,;-12.46,-1.99,;-13.96,-1.67,;-14.73,-3,;-16.26,-3.16,;-13.7,-4.15,;-2.96,-1.21,;-2.96,.33,;-1.63,1.1,;-.29,.33,;-.29,-1.21,;-1.63,-1.98,;-1.63,-3.52,;1.04,-1.98,;1.04,-3.52,;2.38,-4.29,;3.71,-3.52,;3.71,-1.98,;2.38,-1.21,;2.38,.33,;5.04,-1.21,;5.04,.33,;6.38,1.1,;7.71,.33,;9.04,1.1,;10.38,.33,;11.71,1.1,;13.2,.7,;13.6,2.19,;12.11,2.59,;14.93,2.96,;16.26,2.19,;15.7,4.29,;14.16,4.29,;7.71,-1.21,;9.04,-1.98,;9.04,-3.52,;6.38,-1.98,)|

BDBM452220

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H](C2)S(C)(=O)=O)c(OC)n1 |r,wU:11.11,37.40,39.45,(-8.29,.33,;-8.29,-1.21,;-6.96,-1.98,;-5.63,-1.21,;-4.29,-1.98,;-4.29,-3.52,;-5.63,-4.29,;-6.96,-3.52,;-8.29,-4.29,;-9.63,-3.52,;-10.96,-4.29,;-12.3,-3.52,;-12.46,-1.99,;-13.96,-1.67,;-14.73,-3,;-16.26,-3.16,;-13.7,-4.15,;-2.96,-1.21,;-2.96,.33,;-1.63,1.1,;-.29,.33,;-.29,-1.21,;-1.63,-1.98,;-1.63,-3.52,;1.04,-1.98,;1.04,-3.52,;2.38,-4.29,;3.71,-3.52,;3.71,-1.98,;2.38,-1.21,;2.38,.33,;5.04,-1.21,;5.04,.33,;6.38,1.1,;7.71,.33,;9.04,1.1,;10.38,.33,;11.71,1.1,;12.11,2.59,;13.6,2.19,;13.2,.7,;14.93,2.96,;16.26,2.19,;15.7,4.29,;14.16,4.29,;7.71,-1.21,;9.04,-1.98,;9.04,-3.52,;6.38,-1.98,)|

BDBM452221

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CCOC2)c(OC)n1 |r|

BDBM452222

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCOC2)c(OC)n1 |r|

BDBM452223

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@@H](C2)NC(C)=O)c(OC)n1 |r,wU:11.11,39.45,wD:37.40,(-8.96,1,;-8.96,-.54,;-7.63,-1.31,;-6.29,-.54,;-4.96,-1.31,;-4.96,-2.85,;-6.29,-3.62,;-7.63,-2.85,;-8.96,-3.62,;-10.29,-2.85,;-11.63,-3.62,;-12.96,-2.85,;-13.12,-1.32,;-14.63,-1,;-15.4,-2.34,;-16.93,-2.5,;-14.37,-3.48,;-3.63,-.54,;-3.63,1,;-2.29,1.77,;-.96,1,;-.96,-.54,;-2.29,-1.31,;-2.29,-2.85,;.37,-1.31,;.37,-2.85,;1.71,-3.62,;3.04,-2.85,;3.04,-1.31,;1.71,-.54,;1.71,1,;4.38,-.54,;4.38,1,;5.71,1.77,;7.04,1,;8.38,1.77,;9.71,1,;11.04,1.77,;12.53,1.37,;12.93,2.85,;11.44,3.25,;14.26,3.62,;15.6,2.85,;16.93,3.62,;15.6,1.31,;7.04,-.54,;8.38,-1.31,;8.38,-2.85,;5.71,-1.31,)|

BDBM452224

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H](C2)NC(C)=O)c(OC)n1 |r,wU:11.11,37.40,39.45,(-8.96,1,;-8.96,-.54,;-7.63,-1.31,;-6.29,-.54,;-4.96,-1.31,;-4.96,-2.85,;-6.29,-3.62,;-7.63,-2.85,;-8.96,-3.62,;-10.29,-2.85,;-11.63,-3.62,;-12.96,-2.85,;-13.12,-1.32,;-14.63,-1,;-15.4,-2.34,;-16.93,-2.5,;-14.37,-3.48,;-3.63,-.54,;-3.63,1,;-2.29,1.77,;-.96,1,;-.96,-.54,;-2.29,-1.31,;-2.29,-2.85,;.37,-1.31,;.37,-2.85,;1.71,-3.62,;3.04,-2.85,;3.04,-1.31,;1.71,-.54,;1.71,1,;4.38,-.54,;4.38,1,;5.71,1.77,;7.04,1,;8.38,1.77,;9.71,1,;11.04,1.77,;11.44,3.25,;12.93,2.85,;12.53,1.37,;14.26,3.62,;15.6,2.85,;16.93,3.62,;15.6,1.31,;7.04,-.54,;8.38,-1.31,;8.38,-2.85,;5.71,-1.31,)|

BDBM452225

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CC3(C2)CS(=O)(=O)C3)c(OC)n1 |r|

BDBM452226

CO[C@H]1C[C@@H](C1)NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r,wU:37.40,2.1,wD:4.6,(16.26,2.85,;14.93,3.62,;13.6,2.85,;13.2,1.37,;11.71,1.77,;12.11,3.25,;10.38,1,;9.04,1.77,;7.71,1,;6.38,1.77,;5.04,1,;5.04,-.54,;6.38,-1.31,;7.71,-.54,;9.04,-1.31,;9.04,-2.85,;3.71,-1.31,;3.71,-2.85,;2.38,-3.62,;1.04,-2.85,;1.04,-1.31,;2.38,-.54,;2.38,1,;-.29,-.54,;-.29,1,;-1.63,1.77,;-2.96,1,;-2.96,-.54,;-1.63,-1.31,;-1.63,-2.85,;-4.29,-1.31,;-4.29,-2.85,;-5.63,-3.62,;-6.96,-2.85,;-8.29,-3.62,;-9.63,-2.85,;-10.96,-3.62,;-12.3,-2.85,;-12.46,-1.32,;-13.96,-1,;-14.73,-2.34,;-16.26,-2.5,;-13.7,-3.48,;-6.96,-1.31,;-8.29,-.54,;-8.29,1,;-5.63,-.54,)|

BDBM452227

CO[C@@H]1C[C@@H](C1)NCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r,wU:37.40,4.6,2.1,(16.26,2.85,;14.93,3.62,;13.6,2.85,;12.11,3.25,;11.71,1.77,;13.2,1.37,;10.38,1,;9.04,1.77,;7.71,1,;6.38,1.77,;5.04,1,;5.04,-.54,;6.38,-1.31,;7.71,-.54,;9.04,-1.31,;9.04,-2.85,;3.71,-1.31,;3.71,-2.85,;2.38,-3.62,;1.04,-2.85,;1.04,-1.31,;2.38,-.54,;2.38,1,;-.29,-.54,;-.29,1,;-1.63,1.77,;-2.96,1,;-2.96,-.54,;-1.63,-1.31,;-1.63,-2.85,;-4.29,-1.31,;-4.29,-2.85,;-5.63,-3.62,;-6.96,-2.85,;-8.29,-3.62,;-9.63,-2.85,;-10.96,-3.62,;-12.3,-2.85,;-12.46,-1.32,;-13.96,-1,;-14.73,-2.34,;-16.26,-2.5,;-13.7,-3.48,;-6.96,-1.31,;-8.29,-.54,;-8.29,1,;-5.63,-.54,)|

BDBM452228

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@@H](C2)C(C)(C)O)c(OC)n1 |r,wU:11.11,37.40,wD:39.45,(-8.29,.23,;-8.29,-1.31,;-6.96,-2.08,;-5.63,-1.31,;-4.29,-2.08,;-4.29,-3.62,;-5.63,-4.39,;-6.96,-3.62,;-8.29,-4.39,;-9.63,-3.62,;-10.96,-4.39,;-12.3,-3.62,;-12.46,-2.09,;-13.96,-1.77,;-14.73,-3.11,;-16.26,-3.27,;-13.7,-4.25,;-2.96,-1.31,;-2.96,.23,;-1.63,1,;-.29,.23,;-.29,-1.31,;-1.63,-2.08,;-1.63,-3.62,;1.04,-2.08,;1.04,-3.62,;2.38,-4.39,;3.71,-3.62,;3.71,-2.08,;2.38,-1.31,;2.38,.23,;5.04,-1.31,;5.04,.23,;6.38,1,;7.71,.23,;9.04,1,;10.38,.23,;11.71,1,;12.11,2.48,;13.6,2.08,;13.2,.6,;14.93,2.85,;16.26,2.08,;14.93,4.39,;16.26,3.62,;7.71,-1.31,;9.04,-2.08,;9.04,-3.62,;6.38,-2.08,)|

BDBM452229

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CS(=O)(=O)C3)c(OC)n1 |r|

BDBM452230

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1 |r|

BDBM452231

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)NC(C)=O)c(OC)n1 |r|

BDBM452232

COc1nc(cnc1CNCCn1ccccc1=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452233

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1 |r|

BDBM452234

COc1nc(cnc1CNCCN1CCCC1=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452235

COc1nc(cnc1CNCCNC(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452236

COc1nc(cnc1CNCCO)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452237

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(C)(C)CNC(C)=O)c(OC)n1 |r|

BDBM452238

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC(C)(C)NC(C)=O)c(OC)n1 |r|

BDBM452239

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(C)(C)CO)c(OC)n1 |r|

BDBM452240

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC(C)(C)O)c(OC)n1 |r|

BDBM452241

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(OC)n1 |r|

BDBM452242

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](O)C2)c(OC)n1 |r|

BDBM452243

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCC[C@@H]2O)c(OC)n1 |r|

BDBM452244

COc1nc(cnc1CNCC(C)(C)O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC(C)(C)O)c(OC)n1

BDBM452245

COc1nc(cnc1CN[C@@H]1CCC[C@@H]1O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCC[C@@H]2O)c(OC)n1 |r|

BDBM452246

COc1nc(cnc1CNC(C)(C)CO)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(C)(C)CO)c(OC)n1

BDBM452247

COc1nc(cnc1[C@H](C)N)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc([C@H](C)N)c(OC)n1 |r|

BDBM452248

COc1nc(cnc1[C@@H](C)N)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc([C@@H](C)N)c(OC)n1 |r|

BDBM452249

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CC[C@@H]3CC(=O)N[C@H]23)c(OC)n1 |r|

BDBM452250

COc1nc(cnc1CN[C@@H]1CC[C@@H]2CC(=O)N[C@H]12)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CC[C@@H]3CC(=O)N[C@H]23)c(OC)n1 |r|

BDBM452251

COc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Br)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM452252

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Br)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM452253

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Br)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM452254

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Br)-c1cnc(CNC[C@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452255

COc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1F)-c1cccc(c1Br)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM452256

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1F)-c1cccc(c1Br)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM452257

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1F)-c1cccc(c1Br)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM452258

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1F)-c1cccc(c1Br)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452259

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cc(F)cc(c1Cl)-c1cc(F)cc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452260

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cc(F)cc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452261

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cc(F)cc(c1Cl)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM452262

COC1CN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CN3CC(C3)OC)c(OC)n2)C1

BDBM452263

COc1nc(cnc1CN(C)C)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)C)c(OC)n1

BDBM452264

CNCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC)c(OC)n1

BDBM452265

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CC(=O)NC2=O)c(OC)n1 |r|

BDBM452266

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)c2cnccn2)c(OC)n1 |r|

BDBM452267

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)c2cccnc2)c(OC)n1 |r|

BDBM452268

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)c2ccccn2)c(OC)n1 |r|

BDBM452269

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(O)(CC#N)C2)c(OC)n1 |r|

BDBM452270

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)c2ncccn2)c(OC)n1 |r|

BDBM452271

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)C2CCCO2)c(OC)n1 |r|

BDBM452272

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)c2ccncc2)c(OC)n1 |r|

BDBM452273

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)C2CCOC2)c(OC)n1 |r|

BDBM452274

COc1nc(cnc1CNCCc1cncc(O)c1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452275

COc1nc(cnc1CNCC(O)CN1CCCC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452276

COc1ccnc2CN(Cc3ncc(nc3OC)-c3cccc(c3Cl)-c3cccc(c3Cl)-c3cnc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)Cc12 |r|

BDBM452277

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCN(CC2)C(=O)c2ccoc2)c(OC)n1 |r|

BDBM452278

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCN(C)C(=O)C2)c(OC)n1 |r|

BDBM452279

COc1nc(cnc1CNCCc1ccccn1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452280

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2ccccn2)c(OC)n1 |r|

BDBM452281

COc1nc(cnc1CNCCCc1nc2ccccc2[nH]1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452282

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2ncccn2)c(OC)n1 |r|

BDBM452283

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2(CC2)c2ccccn2)c(OC)n1 |r|

BDBM452284

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2ccncc2)c(OC)n1 |r|

BDBM452285

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](O)C[C@H]2CO)c(OC)n1 |r|

BDBM452286

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2(CC2)c2cccnc2)c(OC)n1 |r|

BDBM452287

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2cccnc2)c(OC)n1 |r|

BDBM452288

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(O)CC2)c(OC)n1 |r|

BDBM452289

CO[C@@H]1CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452290

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC(CO)(CO)CO)c(OC)n1 |r|

BDBM452291

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(CC2)C#N)c(OC)n1 |r|

BDBM452292

CO[C@H]1CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452293

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](O)C2)c(OC)n1 |r|

BDBM452294

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@](O)(CF)C2)c(OC)n1 |r,wU:11.11,37.40,39.43,wD:39.44,(-7.63,1,;-7.63,-.54,;-6.29,-1.31,;-4.96,-.54,;-3.63,-1.31,;-3.63,-2.85,;-4.96,-3.62,;-6.29,-2.85,;-7.63,-3.62,;-8.96,-2.85,;-10.29,-3.62,;-11.63,-2.85,;-11.79,-1.32,;-13.3,-1,;-14.07,-2.34,;-15.6,-2.5,;-13.04,-3.48,;-2.29,-.54,;-2.29,1,;-.96,1.77,;.37,1,;.37,-.54,;-.96,-1.31,;-.96,-2.85,;1.71,-1.31,;1.71,-2.85,;3.04,-3.62,;4.38,-2.85,;4.38,-1.31,;3.04,-.54,;3.04,1,;5.71,-.54,;5.71,1,;7.04,1.77,;8.38,1,;9.71,1.77,;11.04,1,;12.38,1.77,;12.78,3.25,;14.26,2.85,;15.6,3.62,;15.6,2.08,;15.6,.54,;13.87,1.37,;8.38,-.54,;9.71,-1.31,;9.71,-2.85,;7.04,-1.31,)|

BDBM452295

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2OCCO2)c(OC)n1 |r|

BDBM452296

COc1nc(cnc1CNCC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452297

COc1nc(cnc1CNC[C@@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452298

COc1nc(ccc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN)c(OC)n1

BDBM452299

COc1nc(ccc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM452300

COC1CN(Cc2ccc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CN3CC(C3)OC)c(OC)n2)C1

BDBM452301

COc1nc(ccc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM452302

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)cn1 |r|

BDBM452303

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)c2cn[nH]c2)c(OC)n1 |r|

BDBM452304

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C)(CO)C2)c(OC)n1 |r|

BDBM452305

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C)(C2)OC)c(OC)n1 |r|

BDBM452306

COc1nc(cnc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM452307

COc1nc(cnc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM452308

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(O)C2)c(OC)n1 |r|

BDBM452309

COc1nc(cnc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM452310

COc1nc(cnc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](CO)C2)c(OC)n1 |r|

BDBM452311

COc1nc(cnc1CNCCO)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(O)C2)c(OC)n1

BDBM452312

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CC4(C3)CCC(=O)N4)cn(C)c2c1

BDBM452313

COc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CC4(C3)CN(C4)C(C)=O)cn(C)c2c1

BDBM452314

CCC(=O)NC1CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452315

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC2(C)CO)c(OC)n1 |r|

BDBM452316

COc1nc(cnc1CNCCOC(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCCOC(N)=O)c(OC)n1

BDBM452317

COc1nc(cnc1CNCc1cnn(CCO)c1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2cnn(CCO)c2)c(OC)n1

BDBM452318

COc1nc(cnc1CNCc1cn[nH]c1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCc2cn[nH]c2)c(OC)n1

BDBM452319

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(CC2)[C@H](C)O)c(OC)n1 |r|

BDBM452320

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CC[C@H](C2)C#N)c(OC)n1 |r|

BDBM452321

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)C[C@H]2C[C@H](O)C2)c(OC)n1 |r,wU:11.11,41.45,wD:39.42,(-8.29,1.93,;-8.29,.38,;-6.96,-.38,;-5.63,.38,;-4.29,-.38,;-4.29,-1.93,;-5.63,-2.69,;-6.96,-1.93,;-8.29,-2.69,;-9.63,-1.93,;-10.96,-2.69,;-12.3,-1.93,;-12.46,-.39,;-13.96,-.07,;-14.73,-1.41,;-16.26,-1.57,;-13.7,-2.55,;-2.96,.38,;-2.96,1.93,;-1.63,2.69,;-.29,1.93,;-.29,.38,;-1.63,-.38,;-1.63,-1.93,;1.04,-.38,;1.04,-1.93,;2.38,-2.69,;3.71,-1.93,;3.71,-.38,;2.38,.38,;2.38,1.93,;5.04,.38,;5.04,1.93,;6.38,2.69,;7.71,1.93,;9.04,2.69,;10.38,1.93,;10.38,.38,;11.71,2.69,;13.04,1.93,;13.44,.44,;14.93,.84,;16.26,.07,;14.53,2.32,;7.71,.38,;9.04,-.38,;9.04,-1.93,;6.38,-.38,)|

BDBM452322

COCC1(CO)CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CN3CCC(CO)(COC)C3)c(OC)n2)C1

BDBM452323

COc1nc(cnc1CNCCc1nnc[nH]1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452324

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)c2nnc[nH]2)c(OC)n1 |r|

BDBM452325

COCC1(CO)CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452326

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H](C2)C(N)=O)c(OC)n1 |r,wU:11.11,37.40,39.45,(-8.29,.23,;-8.29,-1.31,;-6.96,-2.08,;-5.63,-1.31,;-4.29,-2.08,;-4.29,-3.62,;-5.63,-4.39,;-6.96,-3.62,;-8.29,-4.39,;-9.63,-3.62,;-10.96,-4.39,;-12.3,-3.62,;-12.46,-2.09,;-13.96,-1.77,;-14.73,-3.11,;-16.26,-3.27,;-13.7,-4.25,;-2.96,-1.31,;-2.96,.23,;-1.63,1,;-.29,.23,;-.29,-1.31,;-1.63,-2.08,;-1.63,-3.62,;1.04,-2.08,;1.04,-3.62,;2.38,-4.39,;3.71,-3.62,;3.71,-2.08,;2.38,-1.31,;2.38,.23,;5.04,-1.31,;5.04,.23,;6.38,1,;7.71,.23,;9.04,1,;10.38,.23,;11.71,1,;12.11,2.48,;13.6,2.08,;13.2,.6,;14.93,2.85,;14.93,4.39,;16.26,2.08,;7.71,-1.31,;9.04,-2.08,;9.04,-3.62,;6.38,-2.08,)|

BDBM452327

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@@H](C2)C(N)=O)c(OC)n1 |r,wU:11.11,37.40,wD:39.45,(-8.29,.23,;-8.29,-1.31,;-6.96,-2.08,;-5.63,-1.31,;-4.29,-2.08,;-4.29,-3.62,;-5.63,-4.39,;-6.96,-3.62,;-8.29,-4.39,;-9.63,-3.62,;-10.96,-4.39,;-12.3,-3.62,;-12.46,-2.09,;-13.96,-1.77,;-14.73,-3.11,;-16.26,-3.27,;-13.7,-4.25,;-2.96,-1.31,;-2.96,.23,;-1.63,1,;-.29,.23,;-.29,-1.31,;-1.63,-2.08,;-1.63,-3.62,;1.04,-2.08,;1.04,-3.62,;2.38,-4.39,;3.71,-3.62,;3.71,-2.08,;2.38,-1.31,;2.38,.23,;5.04,-1.31,;5.04,.23,;6.38,1,;7.71,.23,;9.04,1,;10.38,.23,;11.71,1,;12.11,2.48,;13.6,2.08,;13.2,.6,;14.93,2.85,;14.93,4.39,;16.26,2.08,;7.71,-1.31,;9.04,-2.08,;9.04,-3.62,;6.38,-2.08,)|

BDBM452328

COc1nc(cnc1CNC1CCN(CC1)C(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCN(CC2)C(N)=O)c(OC)n1

BDBM452329

COc1nc(cnc1CNCC1CCN(C1)C(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCN(C2)C(N)=O)c(OC)n1

BDBM452330

CNC(=O)C1CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CC3CCN(C3)C(=O)NC)c(OC)n2)C1

BDBM452331

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCC2C)c(OC)n1 |r|

BDBM452332

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCN(CC2)C(N)=O)c(OC)n1 |r|

BDBM452333

COc1nc(cnc1CNCC1CCN(C1)C(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452334

CNC(=O)C1CCN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452335

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H]2CCC(C2)C(N)=O)c(OC)n1 |r|

BDBM452336

COc1nc(cnc1CN1C2CC1COC2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C3CC2COC3)c(OC)n1

BDBM452337

COc1nc(cnc1CNC[C@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CNC(=O)C2)c(OC)n1 |r|

BDBM452338

COc1nc(cnc1CNC[C@H]1CCC[C@@H]1O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCC[C@@H]2O)c(OC)n1 |r|

BDBM452339

COc1nc(cnc1CN1CC2CC1(CO)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3CC2(CO)C3)c(OC)n1 |(-7.34,-5,;-6,-4.23,;-6,-2.69,;-4.67,-1.92,;-4.67,-.38,;-6,.39,;-7.34,-.38,;-7.34,-1.92,;-8.67,-2.69,;-10,-1.92,;-10.16,-.39,;-11.67,-.07,;-12.44,-1.41,;-11.41,-2.55,;-11.73,-4.06,;-13.19,-4.53,;-11.01,-1.06,;-3.33,.39,;-3.33,1.93,;-2,2.7,;-.67,1.93,;-.67,.39,;-2,-.38,;-2,-1.92,;.67,-.38,;.67,-1.92,;2,-2.69,;3.33,-1.92,;3.33,-.38,;2,.39,;2,1.93,;4.67,.39,;6,-.38,;7.34,.39,;7.34,1.93,;8.67,2.7,;10,1.93,;10.16,.39,;11.67,.07,;12.44,1.41,;11.41,2.55,;11.73,4.06,;13.19,4.53,;11.01,1.06,;6,2.7,;6,4.24,;4.67,5,;4.67,1.93,)|

BDBM452340

COc1nc(cnc1CN1CC(C1)C(C)(C)O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)C(C)(C)O)c(OC)n1

BDBM452341

COc1nc(cnc1CNCN1C[C@H](C)[C@@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](C)[C@@H](O)C2)c(OC)n1 |r|

BDBM452342

COc1nc(cnc1CNC[C@@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CNC(=O)C2)c(OC)n1 |r|

BDBM452343

COc1nc(cnc1CNC[C@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452344

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@]3(O)C[C@@H]3C2)c(OC)n1 |r|

BDBM452345

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCCC2C(C)(C)O)c(OC)n1 |r|

BDBM452346

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)C(C)(C)O)c(OC)n1 |r|

BDBM452347

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C3CC2COC3)c(OC)n1 |r|

BDBM452348

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(O)CCC2)c(OC)n1 |r|

BDBM452349

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](C)[C@@H](O)C2)c(OC)n1 |r|

BDBM452350

CNc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452351

COc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CC4(C3)CN(C4)C(C)=O)nn(C)c2n1

BDBM452352

CCn1nc(CN2CC3(C2)CN(C3)C(C)=O)c2ncc(nc12)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM452353

COc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc2c(CN3CC4(C3)CN(C4)C(C)=O)cn(C)c2n1

BDBM452354

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc2c(CN3CC(O)C3)cn(C)c2n1

BDBM452355

COc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc2c(CN3CC4(C3)CNC(=O)C4)cn(C)c2n1

BDBM452356

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc2c(CN3CC4(C3)CCC(=O)N4)cn(C)c2n1

BDBM452357

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc2c(CNC[C@@H]3CCC(=O)N3)cn(C)c2n1 |r|

BDBM452358

OC1CN(Cc2ncc(nc2N2CCC2)-c2cccc(c2Cl)-c2cccc(-c3cnc(CN4CC(O)C4)c(n3)N3CCC3)c2Cl)C1

BDBM452359

COc1nc(ccc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1F)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM452360

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1F)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452361

COc1nc(cnc1CN1CC[C@H](C1)C(C)(C)O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](C2)C(C)(C)O)c(OC)n1 |r|

BDBM452362

COc1nc(cnc1CN1CC[C@@H](C1)C(C)(C)O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](C2)C(C)(C)O)c(OC)n1 |r|

BDBM452363

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](C2)C(C)(C)O)c(OC)n1 |r|

BDBM452364

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](C2)C(C)(C)O)c(OC)n1 |r|

BDBM452365

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(CC2)C(N)=O)c(OC)n1 |r|

BDBM452366

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CCOCC2)c(OC)n1 |r|

BDBM452367

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@](C)(O)C2)c(OC)n1 |r|

BDBM452368

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H](CO)C2)c(OC)n1 |r,wU:11.11,37.40,wD:39.43,(-4.29,-4.78,;-5.63,-4.01,;-5.63,-2.47,;-4.29,-1.7,;-4.29,-.16,;-5.63,.61,;-6.96,-.16,;-6.96,-1.7,;-8.29,-2.47,;-9.63,-1.7,;-10.96,-2.47,;-12.3,-1.7,;-12.46,-.17,;-13.96,.15,;-14.73,-1.18,;-16.26,-1.34,;-13.7,-2.33,;-2.96,.61,;-2.96,2.15,;-1.63,2.92,;-.29,2.15,;-.29,.61,;-1.63,-.16,;-1.63,-1.7,;1.04,-.16,;1.04,-1.7,;2.38,-2.47,;3.71,-1.7,;3.71,-.16,;2.38,.61,;2.38,2.15,;5.04,.61,;5.04,2.15,;6.38,2.92,;7.71,2.15,;9.04,2.92,;10.38,2.15,;11.71,2.92,;12.11,4.41,;13.6,4.01,;14.93,4.78,;16.26,4.01,;13.2,2.52,;7.71,.61,;9.04,-.16,;9.04,-1.7,;6.38,-.16,)|

BDBM452369

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCCC(O)=O)c(OC)n1 |r|

BDBM452370

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](C2)C(O)=O)c(OC)n1 |r|

BDBM452371

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](C2)C(O)=O)c(OC)n1 |r|

BDBM452372

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)c2cc[nH]n2)c(OC)n1 |r|

BDBM452373

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](O)[C@@H]2C)c(OC)n1 |r|

BDBM452374

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](C2)C(N)=O)c(OC)n1 |r|

BDBM452376

COc1nc(cnc1CNCCc1cnccn1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCCc2cnccn2)c(OC)n1

BDBM452377

COc1nc(cnc1CN1C[C@H](O)[C@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](O)[C@H](O)C2)c(OC)n1 |r|

BDBM452378

COc1nc(cnc1CNCCc1cncnc1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452379

COc1nc(cnc1CNCCc1cnccn1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452380

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(CCO)CCO)c(OC)n1 |r|

BDBM452381

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(O)(CO)C2)c(OC)n1 |r|

BDBM452382

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](O)[C@H](O)C2)c(OC)n1 |r|

BDBM452383

COc1nc(cnc1CN1CCC(C1)N1CCNC1=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)N2CCNC2=O)c(OC)n1

BDBM452384

COc1nc(cnc1CN1C[C@H](O)[C@@H](O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](O)[C@@H](O)C2)c(OC)n1 |r|

BDBM452386

COc1nc(cnc1CN1CC(C1)C(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)C(N)=O)c(OC)n1

BDBM452387

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)N2CCNC2=O)c(OC)n1 |r|

BDBM452388

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@H](O)[C@@H](O)C2)c(OC)n1 |r|

BDBM452389

COC[C@@H]1C[C@@H](CN1Cc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1)OC |r|

BDBM452390

COc1nc(cnc1CN1CCC(C1)C(=O)N(C)C)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)C(=O)N(C)C)c(OC)n1

BDBM452391

COc1nc(cnc1CN1CC[C@H](C1)C(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](C2)C(N)=O)c(OC)n1 |r|

BDBM452392

COc1nc(cnc1CN1C[C@@H](C)[C@H](CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2C[C@@H](C)[C@H](CO)C2)c(OC)n1 |r|

BDBM452393

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(C2)C(=O)N(C)C)c(OC)n1 |r|

BDBM452394

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](C2)C(N)=O)c(OC)n1 |r|

BDBM452395

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H](C2)OC(F)F)c(OC)n1 |r,wU:11.11,37.40,39.45,(-8.29,-.16,;-8.29,-1.7,;-6.96,-2.47,;-5.63,-1.7,;-4.29,-2.47,;-4.29,-4.01,;-5.63,-4.78,;-6.96,-4.01,;-8.29,-4.78,;-9.63,-4.01,;-10.96,-4.78,;-12.3,-4.01,;-12.46,-2.48,;-13.96,-2.16,;-14.73,-3.49,;-16.26,-3.65,;-13.7,-4.64,;-2.96,-1.7,;-2.96,-.16,;-1.63,.61,;-.29,-.16,;-.29,-1.7,;-1.63,-2.47,;-1.63,-4.01,;1.04,-2.47,;1.04,-4.01,;2.38,-4.78,;3.71,-4.01,;3.71,-2.47,;2.38,-1.7,;2.38,-.16,;5.04,-1.7,;5.04,-.16,;6.38,.61,;7.71,-.16,;9.04,.61,;10.38,-.16,;11.71,.61,;12.11,2.1,;13.6,1.7,;13.2,.21,;14.93,2.47,;14.93,4.01,;13.6,4.78,;16.26,4.78,;7.71,-1.7,;9.04,-2.47,;9.04,-4.01,;6.38,-2.47,)|

BDBM452396

COc1nc(cnc1CN1CCC2(CCC(=O)N2)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC3(CCC(=O)N3)C2)c(OC)n1

BDBM452397

COc1nc(cnc1CNCC[C@@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC[C@@H]2CNC(=O)C2)c(OC)n1 |r|

BDBM452398

COc1nc(cnc1CNCC[C@@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452399

COc1nc(cnc1CNCC[C@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC[C@H]2CNC(=O)C2)c(OC)n1 |r|

BDBM452400

COc1nc(cnc1CNCC[C@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452401

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC[C@H]3[C@@H]2CNC3=O)c(OC)n1 |r|

BDBM452402

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCN(C)C2=O)c(OC)n1 |r|

BDBM452403

COc1nc(cnc1CNCC12CC(O)(C1)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC23CC(O)(C2)C3)c(OC)n1

BDBM452404

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC23CC(O)(C2)C3)c(OC)n1 |r|

BDBM452405

COc1nc(cnc1CNCC1CN(C1)S(C)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CN(C2)S(C)(=O)=O)c(OC)n1

BDBM452406

COc1nc(cnc1CNCC1CN(C1)S(C)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452407

COc1nc(cnc1CN1CC(O)(C1)C1CC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)(C2)C2CC2)c(OC)n1

BDBM452408

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)(C2)C2CC2)c(OC)n1 |r|

BDBM452409

COc1nc(cnc1CN1CC(O)(C1)C#C)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)(C2)C#C)c(OC)n1

BDBM452410

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)(C2)C#C)c(OC)n1 |r|

BDBM452411

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](C2)C(O)=O)c(OC)n1 |r|

BDBM452412

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@](C)(CO)C(O)=O)c(OC)n1 |r|

BDBM452413

CNC(=O)NC1CN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CN3CC(C3)NC(=O)NC)c(OC)n2)C1

BDBM452414

CNC(=O)C1CN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CN3CC(C3)C(=O)NC)c(OC)n2)C1

BDBM452415

COc1nc(cnc1CN1CC(C1)NS(C)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)NS(C)(=O)=O)c(OC)n1

BDBM452416

CNC(=O)NC1CN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452417

CNC(=O)C1CN(Cc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r|

BDBM452418

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)NS(C)(=O)=O)c(OC)n1 |r|

BDBM452419

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2CS(=O)(=O)C2)c(OC)n1 |r|

BDBM452420

COc1nc(cnc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@](C)(O)C2)c(OC)n1 |r,wU:36.39,38.42,10.10,12.13,wD:38.43,12.14,(-8.67,1.92,;-8.67,.38,;-7.34,-.39,;-6,.38,;-4.67,-.39,;-4.67,-1.93,;-6,-2.7,;-7.34,-1.93,;-8.67,-2.7,;-10,-1.92,;-11.34,-2.69,;-12.11,-4.03,;-13.44,-3.26,;-14.21,-4.59,;-14.77,-2.49,;-12.67,-1.92,;-3.33,.38,;-3.33,1.92,;-2,2.69,;-.67,1.92,;-.67,.38,;-2,-.39,;-2,-1.93,;.67,-.39,;.67,-1.93,;2,-2.7,;3.33,-1.93,;3.33,-.39,;2,.38,;2,1.92,;4.67,.38,;4.67,1.92,;6,2.69,;7.34,1.92,;8.67,2.69,;10,1.92,;11.34,2.69,;12.11,4.03,;13.44,3.26,;14.21,4.59,;14.77,2.49,;12.67,1.92,;7.34,.38,;8.67,-.39,;8.67,-1.93,;6,-.39,)|

BDBM452421

COc1nc(cnc1CNC[C@H]1C[C@@](C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2C[C@@](C)(O)C2)c(OC)n1 |r,wU:38.41,40.45,11.11,13.15,wD:40.44,13.14,(-8.59,1.93,;-8.59,.38,;-7.26,-.38,;-5.92,.38,;-4.59,-.38,;-4.59,-1.93,;-5.92,-2.69,;-7.26,-1.93,;-8.59,-2.69,;-9.93,-1.93,;-11.26,-2.69,;-12.59,-1.93,;-14.08,-2.32,;-14.48,-.84,;-14.48,.7,;-15.97,-.44,;-12.99,-.44,;-3.26,.38,;-3.26,1.93,;-1.92,2.69,;-.59,1.93,;-.59,.38,;-1.92,-.38,;-1.92,-1.93,;.74,-.38,;.74,-1.93,;2.08,-2.69,;3.41,-1.93,;3.41,-.38,;2.08,.38,;2.08,1.93,;4.74,.38,;4.74,1.93,;6.08,2.69,;7.41,1.93,;8.75,2.69,;10.08,1.93,;11.41,2.69,;12.75,1.93,;14.23,2.32,;14.63,.84,;14.63,-.7,;15.97,.07,;13.15,.44,;7.41,.38,;8.75,-.38,;8.75,-1.93,;6.08,-.38,)|

BDBM452422

COc1nc(cnc1CNC[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2C[C@](C)(O)C2)c(OC)n1 |r,wU:38.41,40.44,11.11,13.14,wD:40.45,13.15,(-8.67,1.93,;-8.67,.38,;-7.34,-.38,;-6,.38,;-4.67,-.38,;-4.67,-1.93,;-6,-2.69,;-7.34,-1.93,;-8.67,-2.69,;-10,-1.93,;-11.34,-2.69,;-12.67,-1.93,;-14.16,-2.32,;-14.56,-.84,;-16.04,-1.23,;-14.95,.65,;-13.07,-.44,;-3.33,.38,;-3.33,1.93,;-2,2.69,;-.67,1.93,;-.67,.38,;-2,-.38,;-2,-1.93,;.67,-.38,;.67,-1.93,;2,-2.69,;3.33,-1.93,;3.33,-.38,;2,.38,;2,1.93,;4.67,.38,;4.67,1.93,;6,2.69,;7.34,1.93,;8.67,2.69,;10,1.93,;11.34,2.69,;12.67,1.93,;14.16,2.32,;14.56,.84,;16.04,1.23,;14.95,-.65,;13.07,.44,;7.34,.38,;8.67,-.38,;8.67,-1.93,;6,-.38,)|

BDBM452423

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@](C)(O)C2)c(OC)n1 |r,wU:11.11,37.40,39.43,wD:39.44,(-7.7,.64,;-7.7,-.9,;-6.37,-1.67,;-5.04,-.9,;-3.7,-1.67,;-3.7,-3.21,;-5.04,-3.98,;-6.37,-3.21,;-7.7,-3.98,;-9.04,-3.21,;-10.37,-3.98,;-11.71,-3.21,;-11.87,-1.68,;-13.37,-1.36,;-14.14,-2.7,;-15.67,-2.86,;-13.11,-3.84,;-2.37,-.9,;-2.37,.64,;-1.04,1.41,;.3,.64,;.3,-.9,;-1.04,-1.67,;-1.04,-3.21,;1.63,-1.67,;1.63,-3.21,;2.97,-3.98,;4.3,-3.21,;4.3,-1.67,;2.97,-.9,;2.97,.64,;5.63,-.9,;5.63,.64,;6.97,1.41,;8.3,.64,;9.63,1.41,;10.97,.64,;12.3,1.41,;12.7,2.89,;14.19,2.5,;14.59,3.98,;15.67,2.1,;13.79,1.01,;8.3,-.9,;9.63,-1.67,;9.63,-3.21,;6.97,-1.67,)|

BDBM452424

CO[C@H]1C[C@H](CNCc2ncc(nc2OC)-c2cccc(c2Cl)-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)C1 |r,wU:37.39,4.4,wD:2.1,(16.54,-1.05,;15.05,-.65,;14.65,.84,;14.26,2.32,;12.77,1.93,;11.43,2.69,;10.1,1.93,;8.77,2.69,;7.43,1.93,;6.1,2.69,;4.77,1.93,;4.77,.38,;6.1,-.38,;7.43,.38,;8.77,-.38,;8.77,-1.93,;3.43,-.38,;3.43,-1.93,;2.1,-2.69,;.77,-1.93,;.77,-.38,;2.1,.38,;2.1,1.93,;-.57,.38,;-.57,1.93,;-1.9,2.69,;-3.24,1.93,;-3.24,.38,;-1.9,-.38,;-1.9,-1.93,;-4.57,-.38,;-4.57,-1.93,;-5.9,-2.69,;-7.24,-1.93,;-8.57,-2.69,;-9.9,-1.93,;-11.24,-2.69,;-12.57,-1.93,;-12.73,-.39,;-14.24,-.07,;-15.01,-1.41,;-16.54,-1.57,;-13.98,-2.55,;-7.24,-.38,;-8.57,.38,;-8.57,1.93,;-5.9,.38,;13.17,.44,)|

BDBM452425

COc1nc(cnc1CNC[C@H]1C[C@@](C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r,wU:38.41,11.11,13.15,wD:13.14,(8.97,-1.93,;8.97,-.38,;7.63,.38,;6.3,-.38,;4.97,.38,;4.97,1.93,;6.3,2.69,;7.63,1.93,;8.97,2.69,;10.3,1.93,;11.63,2.69,;12.97,1.93,;14.46,2.32,;14.85,.84,;15.25,-.65,;16.34,1.23,;13.37,.44,;3.63,-.38,;3.63,-1.93,;2.3,-2.69,;.96,-1.93,;.96,-.38,;2.3,.38,;2.3,1.93,;-.37,.38,;-.37,1.93,;-1.7,2.69,;-3.04,1.93,;-3.04,.38,;-1.7,-.38,;-1.7,-1.93,;-4.37,-.38,;-4.37,-1.93,;-5.7,-2.69,;-7.04,-1.93,;-8.37,-2.69,;-9.7,-1.93,;-11.04,-2.69,;-12.37,-1.93,;-12.53,-.39,;-14.04,-.07,;-14.81,-1.41,;-16.34,-1.57,;-13.78,-2.55,;-7.04,-.38,;-8.37,.38,;-8.37,1.93,;-5.7,.38,)|

BDBM452426

COc1nc(cnc1CNC[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r,wU:38.41,11.11,13.14,wD:13.15,(8.97,-1.93,;8.97,-.38,;7.63,.38,;6.3,-.38,;4.97,.38,;4.97,1.93,;6.3,2.69,;7.63,1.93,;8.97,2.69,;10.3,1.93,;11.63,2.69,;12.97,1.92,;14.46,2.32,;14.85,.84,;16.34,1.23,;15.25,-.65,;13.37,.44,;3.63,-.38,;3.63,-1.93,;2.3,-2.69,;.96,-1.93,;.96,-.38,;2.3,.38,;2.3,1.93,;-.37,.38,;-.37,1.93,;-1.7,2.69,;-3.04,1.93,;-3.04,.38,;-1.7,-.38,;-1.7,-1.93,;-4.37,-.38,;-4.37,-1.93,;-5.7,-2.69,;-7.04,-1.93,;-8.37,-2.69,;-9.7,-1.93,;-11.04,-2.69,;-12.37,-1.93,;-12.53,-.39,;-14.04,-.07,;-14.81,-1.41,;-16.34,-1.57,;-13.78,-2.55,;-7.04,-.38,;-8.37,.38,;-8.37,1.93,;-5.7,.38,)|

BDBM452427

COc1nc(cnc1CNC[C@H]1CCS(=O)(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCS(=O)(=O)N2)c(OC)n1 |r|

BDBM452428

COc1nc(cnc1CNC[C@@H]1CCS(=O)(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCS(=O)(=O)N2)c(OC)n1 |r|

BDBM452429

COc1nc(cnc1CNCCCN1CCCS1(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCCCN2CCCS2(=O)=O)c(OC)n1

BDBM452430

COc1nc(cnc1CN1CC(C1)NS(N)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)NS(N)(=O)=O)c(OC)n1

BDBM452431

CNS(=O)(=O)CCNCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452432

COc1nc(cnc1CNCCN1CCCS1(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452433

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)S(C)(=O)=O)c(OC)n1 |r|

BDBM452434

COc1nc(cnc1CNCCNS(C)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCCNS(C)(=O)=O)c(OC)n1

BDBM452435

COc1nc(cnc1CNCC1CCS(=O)(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCS(=O)(=O)N2)c(OC)n1

BDBM452436

COc1nc(cnc1CNCCCS(N)(=O)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452437

CCNC(=O)CNCc1ncc(nc1OC)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452438

COc1nc(cnc1CNC[C@H]1CCOC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2CCOC2)c(OC)n1 |r|

BDBM452439

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN(C)C[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452440

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC(=O)NC(C)C)c(OC)n1 |r|

BDBM452441

COc1nc(ccc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCCN2)c(OC)n1 |t:31|

BDBM452442

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1ccc(C2=NCCN2)c(OC)n1 |t:31|

BDBM452443

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCCN2)c(OC)n1 |t:31|

BDBM452444

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](C2)C(O)=O)c(OC)n1 |r|

BDBM452445

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](O)C2)c(OC)n1 |r|

BDBM452446

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](O)C2)c(OC)n1 |r|

BDBM452447

COc1nc(cnc1CNCC1(O)COC1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(O)COC2)c(OC)n1

BDBM452448

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2(O)COC2)c(OC)n1 |r|

BDBM452449

COc1nc(cnc1CN[C@H](C1CC1)[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H](C2CC2)[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452450

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM452451

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC2C[C@@](C)(O)C2)c(OC)n1 |r,wU:32.36,wD:32.35,(11.02,-.64,;11.02,.9,;9.69,1.67,;8.36,.9,;7.02,1.67,;7.02,3.21,;8.36,3.98,;9.69,3.21,;11.02,3.98,;12.36,3.21,;5.69,.9,;5.69,-.64,;4.35,-1.41,;3.02,-.64,;3.02,.9,;4.35,1.67,;4.35,3.21,;1.69,1.67,;1.69,3.21,;.35,3.98,;-.98,3.21,;-.98,1.67,;.35,.9,;.35,-.64,;-2.31,.9,;-2.31,-.64,;-3.65,-1.41,;-4.98,-.64,;-6.32,-1.41,;-7.65,-.64,;-8.98,-1.41,;-9.38,-2.89,;-10.87,-2.5,;-12.36,-2.1,;-11.27,-3.98,;-10.47,-1.01,;-4.98,.9,;-6.32,1.67,;-6.32,3.21,;-3.65,1.67,)|

BDBM452452

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)C(C)(C)O)c(OC)n1

BDBM452453

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM452454

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM452455

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(O)C2)c(OC)n1

BDBM452456

COc1nc(cnc1CN)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM452457

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@@H](C)[C@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452458

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H](C)[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452459

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@@](O)(CO)C2)c(OC)n1 |r,wU:11.11,37.40,39.44,wD:39.43,(-7.9,.44,;-7.9,-1.1,;-6.57,-1.87,;-5.24,-1.1,;-3.9,-1.87,;-3.9,-3.41,;-5.24,-4.18,;-6.57,-3.41,;-7.9,-4.18,;-9.24,-3.41,;-10.57,-4.18,;-11.9,-3.41,;-12.07,-1.88,;-13.57,-1.56,;-14.34,-2.89,;-15.87,-3.06,;-13.31,-4.04,;-2.57,-1.1,;-2.57,.44,;-1.24,1.21,;.1,.44,;.1,-1.1,;-1.24,-1.87,;-1.24,-3.41,;1.43,-1.87,;1.43,-3.41,;2.77,-4.18,;4.1,-3.41,;4.1,-1.87,;2.77,-1.1,;2.77,.44,;5.43,-1.1,;5.43,.44,;6.77,1.21,;8.1,.44,;9.43,1.21,;10.77,.44,;12.1,1.21,;12.5,2.7,;13.99,2.3,;15.48,1.9,;14.39,3.78,;15.87,4.18,;13.59,.81,;8.1,-1.1,;9.43,-1.87,;9.43,-3.41,;6.77,-1.87,)|

BDBM452460

COc1nc(cnc1CN[C@H](C)[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H](C)[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452461

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CCC4(CCC(=O)N4)C3)cn(C)c2n1 |r|

BDBM452462

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CNC[C@H]3C[C@H](O)C3)cn(C)c2n1 |r,wU:39.42,wD:11.11,41.45,(-8.55,-.36,;-8.55,-1.9,;-7.22,-2.67,;-5.88,-1.9,;-4.55,-2.67,;-4.55,-4.21,;-5.88,-4.98,;-7.22,-4.21,;-8.55,-4.98,;-9.88,-4.21,;-11.22,-4.98,;-12.55,-4.21,;-12.71,-2.68,;-14.22,-2.36,;-14.99,-3.69,;-16.52,-3.85,;-13.96,-4.83,;-3.22,-1.9,;-3.22,-.36,;-1.88,.41,;-.55,-.36,;-.55,-1.9,;-1.88,-2.67,;-1.88,-4.21,;.79,-2.67,;.79,-4.21,;2.12,-4.98,;3.45,-4.21,;3.45,-2.67,;2.12,-1.9,;2.12,-.36,;4.79,-1.9,;4.79,-.36,;6.12,.41,;7.45,-.36,;8.92,.12,;9.39,1.58,;10.9,1.9,;11.38,3.37,;12.88,3.69,;13.72,4.98,;15.01,4.14,;16.52,4.46,;14.17,2.85,;9.82,-1.13,;8.92,-2.37,;9.39,-3.84,;7.45,-1.9,;6.12,-2.67,)|

BDBM452463

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CC4(C3)CN(C4)C(C)=O)cn(C)c2n1 |r|

BDBM452464

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CC4(C3)CNC(=O)C4)cn(C)c2n1 |r|

BDBM452465

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CNC[C@@H]3CCC(=O)N3)cn(C)c2n1 |r|

BDBM452466

COc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CC4(C3)CNC(=O)C4)cn(C)c2n1

BDBM452467

CCn1cc(CN2CC3(C2)CN(C3)C(C)=O)c2ncc(nc12)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM452468

CCn1cc(CN2CC3(C2)CNC(=O)C3)c2ncc(nc12)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM452469

CCn1cc(CN2CC3(C2)CCC(=O)N3)c2ncc(nc12)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM452470

CCn1cc(CN2CC(O)C2)c2ncc(nc12)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM452471

COc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CC4(C3)CN(C4)C(C)=O)cn(C)c2n1

BDBM452472

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc2c(CN3CC4(C3)CCC(=O)N4)cn(C)c2n1

BDBM452473

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1F)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452474

COc1nc(ccc1CNCCO)-c1cccc(c1Cl)-c1cccc(c1F)-c1cnc(CNCCO)c(OC)n1

BDBM452475

COc1nc(ccc1CN1CC[C@@H](CO)C1)-c1cccc(c1Cl)-c1cccc(c1F)-c1cnc(CN2CC[C@@H](CO)C2)c(OC)n1 |r|

BDBM452476

COc1nc(ccc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1Cl)-c1cccc(c1F)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM452477

COc1nc(ccc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1F)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM452478

COc1nc(ccc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1F)-c1cnc(CN2CC(O)C2)c(OC)n1

BDBM452479

COc1nc(cnc1CNCCOc1ccccn1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452480

COc1nc(cnc1CN1CC(C)(N)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(N)C2)c(OC)n1

BDBM452481

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(N)C2)c(OC)n1 |r|

BDBM452482

COc1nc(cnc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452483

COc1nc(cnc1CN1CC[C@H](CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](CO)C2)c(OC)n1 |r|

BDBM452484

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@H](CO)C2)c(OC)n1 |r|

BDBM452485

COc1nc(cnc1CN1CC[C@@H](CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](CO)C2)c(OC)n1 |r|

BDBM452486

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](CO)C2)c(OC)n1 |r|

BDBM452487

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cc(C)c(CNC[C@@H]2CCC(=O)N2)c(OC)n1 |r|

BDBM452488

COc1nc(cnc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(O)C2)c(OC)n1

BDBM452489

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN)c(OC)n1 |r|

BDBM452490

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C)(O)C2)c(OC)n1 |r|

BDBM452491

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1 |r|

BDBM452492

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC)n1 |r|

BDBM452493

COc1nc(cnc1CN1CCC(CO)(CO)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CCC(CO)(CO)C2)c(OC)n1

BDBM452494

COc1nc(ccc1CN1CC(C1)C(C)(C)O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)C(C)(C)O)c(OC2CC2)n1

BDBM452495

COc1nc(ccc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC2CC2)n1

BDBM452496

COc1nc(ccc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CNC(=O)C3)c(OC2CC2)n1

BDBM452497

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC2CC2)n1 |r|

BDBM452498

COc1nc(ccc1CNC[C@@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2C[C@H](C2)C(N)=O)c(OC)n1 |r,wU:11.11,37.40,39.45,(-9.63,-2.08,;-8.29,-1.31,;-6.96,-2.08,;-5.63,-1.31,;-4.29,-2.08,;-4.29,-3.62,;-5.63,-4.39,;-6.96,-3.62,;-8.29,-4.39,;-9.63,-3.62,;-10.96,-4.39,;-12.3,-3.62,;-12.46,-2.09,;-13.96,-1.77,;-14.73,-3.11,;-16.26,-3.27,;-13.7,-4.25,;-2.96,-1.31,;-2.96,.23,;-1.63,1,;-.29,.23,;-.29,-1.31,;-1.63,-2.08,;-1.63,-3.62,;1.04,-2.08,;1.04,-3.62,;2.38,-4.39,;3.71,-3.62,;3.71,-2.08,;2.38,-1.31,;2.38,.23,;5.04,-1.31,;6.38,-2.08,;7.71,-1.31,;7.71,.23,;9.04,1,;10.38,.23,;11.71,1,;12.11,2.48,;13.6,2.08,;13.2,.6,;14.93,2.85,;16.26,2.08,;14.93,4.39,;6.38,1,;6.38,2.54,;7.71,3.31,;5.04,.23,)|

BDBM452499

COc1nc(ccc1CNC[C@@H]1CNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CCC[C@H]2O)c(OC)n1 |r|

BDBM452500

COc1nc(ccc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCCN2)c(OC)n1 |t:41|

BDBM452501

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCCN2)c(OC)n1 |t:37|

BDBM452502

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NC[C@H](C)N2)c(OC)n1 |r,t:39|

BDBM452503

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NC[C@@H](C)N2)c(OC)n1 |r,t:39|

BDBM452504

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NCCN2)c(OC)n1 |r,t:39|

BDBM452505

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NC[C@H](C)N2)c(OC)n1 |r,t:39|

BDBM452506

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(C2=NC[C@@H](C)N2)c(OC)n1 |r,t:39|

BDBM452507

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN[C@H]2CC[C@@H](CO)C2)c(OC)n1 |r|

BDBM452508

COc1nc(ccc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1F)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM452509

COc1nc(cnc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc(c1F)-c1cc(C)c(CN2CC3(C2)CCC(=O)N3)c(OC)n1

BDBM452510

COc1nc(cnc1CN1CC2(C1)CNC(=O)C2)-c1cccc(c1Cl)-c1cccc(c1F)-c1cc(C)c(CN2CC3(C2)CNC(=O)C3)c(OC)n1

BDBM452511

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cc(C)c(CNC[C@H]2C[C@H](O)C2)c(OC)n1 |r,wU:11.11,39.42,wD:41.45,(-8.29,1.15,;-8.29,-.38,;-6.96,-1.15,;-5.62,-.38,;-4.29,-1.15,;-4.29,-2.69,;-5.62,-3.47,;-6.96,-2.69,;-8.29,-3.47,;-9.62,-2.69,;-10.96,-3.47,;-12.29,-2.69,;-12.45,-1.16,;-13.96,-.84,;-14.73,-2.18,;-16.27,-2.18,;-13.7,-3.32,;-2.96,-.38,;-2.96,1.15,;-1.62,1.93,;-.29,1.15,;-.29,-.38,;-1.62,-1.15,;-1.62,-2.69,;1.05,-1.15,;1.05,-2.69,;2.38,-3.47,;3.71,-2.69,;3.71,-1.15,;2.38,-.38,;2.38,1.15,;5.05,-.38,;5.05,1.15,;6.38,1.93,;6.38,3.47,;7.71,1.15,;9.05,1.93,;10.38,1.15,;11.72,1.92,;13.05,1.15,;14.54,1.55,;14.93,.07,;16.27,-.7,;13.45,-.33,;7.71,-.38,;9.05,-1.15,;9.05,-2.69,;6.38,-1.15,)|

BDBM452512

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cc(C)c(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1 |r|

BDBM452513

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cc(C)c(CN2CC(C(O)=O)C3(CCOC3)C2)c(OC)n1 |r|

BDBM452514

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cc(C)c(CN2C[C@@H]3CCC[C@@]3(C2)C(O)=O)c(OC)n1 |r|

BDBM452515

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@H]2C[C@H](O)C2)c(OC)n1 |r,wU:11.11,38.41,wD:40.44,(-8.29,1.93,;-8.29,.38,;-6.96,-.38,;-5.62,.38,;-4.29,-.38,;-4.29,-1.93,;-5.62,-2.69,;-6.96,-1.93,;-8.29,-2.69,;-9.62,-1.93,;-10.96,-2.69,;-12.29,-1.92,;-12.45,-.39,;-13.96,-.07,;-14.73,-1.41,;-16.27,-1.41,;-13.7,-2.55,;-2.96,.38,;-2.96,1.93,;-1.62,2.69,;-.29,1.93,;-.29,.38,;-1.62,-.38,;-1.62,-1.93,;1.05,-.38,;1.05,-1.93,;2.38,-2.69,;3.71,-1.93,;3.71,-.38,;2.38,.38,;2.38,1.93,;5.05,.38,;5.05,1.93,;6.38,2.69,;7.71,1.93,;9.05,2.69,;10.38,1.92,;11.72,2.69,;13.05,1.92,;14.54,2.32,;14.93,.84,;16.27,.07,;13.45,.44,;7.71,.38,;9.05,-.38,;9.05,-1.93,;6.38,-.38,)|

BDBM452516

COc1nc(cnc1CN1CC(C1)OCC(N)=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC(C2)OCC(N)=O)c(OC)n1

BDBM452517

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCNC2=O)c(OC)n1 |r|

BDBM452518

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCNC(=O)C2)c(OC)n1 |r|

BDBM452519

COc1nc(cnc1CNCC1CCNC(=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCNC(=O)C2)c(OC)n1

BDBM452520

COc1nc(cnc1CNCC1CCNC1=O)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNCC2CCNC2=O)c(OC)n1

BDBM452521

COc1nc(cnc1CN1CC2(C1)CN(C2)C(C)=O)-c1cccc(c1C)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CN(C3)C(C)=O)c(OC)n1

BDBM452522

COc1nc(cnc1CN1CC[C@@H](CNC(C)=O)C1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC[C@@H](CNC(C)=O)C2)c(OC)n1 |r|

BDBM461423

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:29.37,(-9.31,.89,;-9.31,-.65,;-7.98,-1.42,;-6.65,-.65,;-5.31,-1.42,;-5.31,-2.96,;-6.65,-3.73,;-7.98,-2.96,;-9.31,-3.73,;-10.65,-2.96,;-11.98,-3.73,;-13.31,-2.96,;-13.31,-1.42,;-14.78,-.94,;-15.68,-2.19,;-17.17,-2.58,;-14.78,-3.43,;-3.98,-.65,;-3.98,.89,;-2.64,1.66,;-1.31,.89,;-1.31,-.65,;-2.64,-1.42,;-2.64,-2.96,;.02,-1.42,;.02,-2.96,;1.36,-3.73,;2.69,-2.96,;2.69,-1.42,;3.83,-.39,;3.21,1.02,;1.68,.86,;1.36,-.65,;5.17,-1.16,;6.5,-.39,;6.5,1.16,;7.84,1.93,;7.84,3.47,;6.5,4.24,;9.17,1.16,;10.5,1.93,;11.84,1.16,;13.17,1.93,;14.5,1.16,;14.5,-.39,;13.17,-1.16,;11.84,-.39,;12.9,-.39,;13.81,.14,;15.84,1.93,;17.17,1.16,;15.84,3.47,;9.17,-.39,;7.84,-1.16,;7.84,-2.7,;6.5,-3.47,;9.17,-3.47,;7.84,-4.24,)|

BDBM461425

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@](C)(C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461426

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@@H](C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461427

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461428

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(-9.31,.64,;-9.31,-.9,;-7.98,-1.67,;-6.65,-.9,;-5.31,-1.67,;-5.31,-3.21,;-6.65,-3.98,;-7.98,-3.21,;-9.31,-3.98,;-10.65,-3.21,;-11.98,-3.98,;-13.31,-3.21,;-13.31,-1.67,;-14.78,-1.19,;-15.68,-2.44,;-17.17,-2.84,;-14.78,-3.69,;-3.98,-.9,;-3.98,.64,;-2.64,1.41,;-1.31,.64,;-1.31,-.9,;-2.64,-1.67,;-2.64,-3.21,;.02,-1.67,;.02,-3.21,;1.36,-3.98,;2.69,-3.21,;2.69,-1.67,;3.83,-.64,;3.21,.77,;1.68,.61,;1.36,-.9,;5.17,-1.41,;6.5,-.64,;6.5,.9,;7.84,1.67,;7.84,3.21,;6.5,3.98,;9.17,.9,;10.5,1.67,;11.84,.9,;13.17,1.67,;14.5,.9,;14.5,-.64,;13.17,-1.41,;11.84,-.64,;12.9,-.64,;13.81,-.11,;15.84,1.67,;17.17,.9,;15.84,3.21,;9.17,-.64,;7.84,-1.41,;7.84,-2.95,)|

BDBM461430

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC(C)(O)C1 |r|

BDBM461431

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC3(C2)CCC(=O)N3)cc1Cl |r|

BDBM461432

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461433

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNC[C@@H]2CCC(=O)N2)cc1Cl |r|

BDBM461434

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC[C@@H](C1)C(O)=O)C(F)(F)F |r|

BDBM461435

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC[C@H](C1)C(O)=O)C(F)(F)F |r|

BDBM461436

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC2(CCC1CC2)C(O)=O)C(F)(F)F |r,wU:29.31,wD:6.5,(6.5,4.24,;7.84,3.47,;7.84,1.93,;6.5,1.16,;6.5,-.39,;5.17,-1.16,;3.83,-.39,;3.21,1.02,;1.68,.86,;1.36,-.65,;2.69,-1.42,;2.69,-2.96,;1.36,-3.73,;.02,-2.96,;.02,-1.42,;-1.31,-.65,;-1.31,.89,;-2.64,1.66,;-3.98,.89,;-3.98,-.65,;-2.64,-1.42,;-2.64,-2.96,;-5.31,-1.42,;-5.31,-2.96,;-6.65,-3.73,;-7.98,-2.96,;-9.31,-3.73,;-10.65,-2.96,;-11.98,-3.73,;-13.31,-2.96,;-13.31,-1.42,;-14.78,-.94,;-15.68,-2.19,;-17.17,-2.58,;-14.78,-3.43,;-7.98,-1.42,;-9.31,-.65,;-9.31,.89,;-6.65,-.65,;7.84,-1.16,;9.17,-.39,;9.17,1.16,;10.5,1.93,;11.84,1.16,;13.17,1.93,;14.5,1.16,;14.5,-.39,;13.17,-1.16,;11.84,-.39,;12.9,-.39,;13.81,.14,;15.84,1.93,;17.17,1.16,;15.84,3.47,;7.84,-2.7,;9.17,-3.47,;6.5,-3.47,;7.84,-4.24,)|

BDBM461437

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC2(CCC1CC2)C(O)=O |r,wU:29.31,wD:6.5,(6.5,3.98,;7.84,3.21,;7.84,1.67,;6.5,.9,;6.5,-.64,;5.17,-1.41,;3.83,-.64,;3.21,.77,;1.68,.61,;1.36,-.9,;2.69,-1.67,;2.69,-3.21,;1.36,-3.98,;.02,-3.21,;.02,-1.67,;-1.31,-.9,;-1.31,.64,;-2.64,1.41,;-3.98,.64,;-3.98,-.9,;-2.64,-1.67,;-2.64,-3.21,;-5.31,-1.67,;-5.31,-3.21,;-6.65,-3.98,;-7.98,-3.21,;-9.31,-3.98,;-10.65,-3.21,;-11.98,-3.98,;-13.31,-3.21,;-13.31,-1.67,;-14.78,-1.19,;-15.68,-2.44,;-17.17,-2.84,;-14.78,-3.69,;-7.98,-1.67,;-9.31,-.9,;-9.31,.64,;-6.65,-.9,;7.84,-1.41,;7.84,-2.95,;9.17,-.64,;9.17,.9,;10.5,1.67,;11.84,.9,;13.17,1.67,;14.5,.9,;14.5,-.64,;13.17,-1.41,;11.84,-.64,;12.9,-.64,;13.81,-.11,;15.84,1.67,;17.17,.9,;15.84,3.21,)|

BDBM461438

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@](C)(C1)C(O)=O |r|

BDBM461439

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@@H](C1)C(O)=O |r|

BDBM461440

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461441

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN)nc1C(F)(F)F |r|

BDBM461442

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)nc1C(F)(F)F |r,wU:11.11,wD:29.37,(-9.31,.89,;-9.31,-.65,;-7.98,-1.42,;-6.65,-.65,;-5.31,-1.42,;-5.31,-2.96,;-6.65,-3.73,;-7.98,-2.96,;-9.31,-3.73,;-10.65,-2.96,;-11.98,-3.73,;-13.31,-2.96,;-13.31,-1.42,;-14.78,-.94,;-15.68,-2.19,;-17.17,-2.58,;-14.78,-3.43,;-3.98,-.65,;-3.98,.89,;-2.64,1.66,;-1.31,.89,;-1.31,-.65,;-2.64,-1.42,;-2.64,-2.96,;.02,-1.42,;.02,-2.96,;1.36,-3.73,;2.69,-2.96,;2.69,-1.42,;3.83,-.39,;3.21,1.02,;1.68,.86,;1.36,-.65,;5.17,-1.16,;6.5,-.39,;6.5,1.16,;7.84,1.93,;7.84,3.47,;9.17,4.24,;9.17,1.16,;10.5,1.93,;11.84,1.16,;13.17,1.93,;14.5,1.16,;14.5,-.39,;13.17,-1.16,;11.84,-.39,;12.9,-.39,;13.81,.14,;15.84,1.93,;17.17,1.16,;15.84,3.47,;9.17,-.39,;7.84,-1.16,;7.84,-2.7,;9.17,-3.47,;6.5,-3.47,;7.84,-4.24,)|

BDBM461443

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)nc1C(F)(F)F |r|

BDBM461444

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@](C)(C2)C(O)=O)nc1C(F)(F)F |r|

BDBM461445

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2C[C@@H]3C[C@@]3(C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461446

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNCC3CCC(=O)N3)c(OC)n2)c(cc1CNC1(CCC1)C(O)=O)C(F)(F)F |r|

BDBM461447

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC4(C3)CCC(=O)N4)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461448

COc1nc(ccc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461449

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461450

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(nc1CN1CC[C@](C)(C1)C(O)=O)C(F)(F)F |r|

BDBM461451

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(cc1CN1CCC[C@@]1(C)C(O)=O)C(F)(F)F |r|

BDBM461452

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(cc1CN1CCC[C@]1(C)C(O)=O)C(F)(F)F |r|

BDBM461453

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461454

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN(C)CC(O)=O)nc1C(F)(F)F |r|

BDBM461455

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)nc1C(F)(F)F |r|

BDBM461456

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNC2(CC2)C(O)=O)nc1C(F)(F)F |r|

BDBM461457

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)nc1C(F)(F)F |r,wU:12.12,wD:30.38,(7.98,-1.41,;7.98,.13,;6.65,.9,;5.31,.13,;3.98,.9,;3.98,2.44,;5.31,3.21,;5.31,4.75,;6.65,2.44,;7.98,3.21,;9.31,2.44,;10.65,3.21,;11.98,2.44,;11.98,.9,;13.45,.42,;14.35,1.67,;15.84,2.07,;13.45,2.92,;2.64,.13,;2.64,-1.41,;1.31,-2.18,;-.02,-1.41,;-.02,.13,;1.31,.9,;1.31,2.44,;-1.36,.9,;-1.36,2.44,;-2.69,3.21,;-4.02,2.44,;-4.02,.9,;-5.17,-.13,;-4.54,-1.54,;-3.01,-1.38,;-2.69,.13,;-6.5,.64,;-7.84,-.13,;-7.84,-1.67,;-9.17,-2.44,;-9.17,-3.98,;-7.84,-4.75,;-10.5,-1.67,;-11.84,-2.44,;-13.17,-1.67,;-13.17,-.13,;-14.5,.64,;-15.84,-.13,;-15.84,-1.67,;-14.5,-2.44,;-15.03,-1.34,;-15.03,-.28,;-14.5,2.18,;-13.17,2.95,;-15.84,2.95,;-10.5,-.13,;-9.17,.64,;-9.17,2.18,;-10.5,2.95,;-7.84,2.95,;-9.17,3.72,)|

BDBM461458

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN(C)CC(O)=O)nc1C(F)(F)F |r|

BDBM461459

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN(C)CC(O)=O)C(F)(F)F |r|

BDBM461460

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461461

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(nc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461462

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CCC[C@]2(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461463

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CCC[C@@]2(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461464

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNC(C)(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461465

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNC2(CC2)C(O)=O)cc1C(F)(F)F |r|

BDBM461466

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(nc1CN1CC[C@](C)(C1)C(O)=O)C(F)(F)F |r|

BDBM461467

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(nc1CN1CC[C@H](C1)C(O)=O)C(F)(F)F |r|

BDBM461468

COc1cc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(nc1CN)C(F)(F)F |r|

BDBM461469

COc1nc(ccc1CNC[C@@H]1CC(O)C(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(O)=O)nc1C(F)(F)F |r|

BDBM461470

COc1nc(ccc1CNC[C@@H]1CC(O)C(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)nc1C(F)(F)F |r|

BDBM461471

COc1nc(ccc1CNC[C@@H]1CC(O)C(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)nc1C(F)(F)F |r,wU:11.11,wD:30.38,(4.55,5.14,;5.88,4.37,;5.88,2.83,;4.55,2.06,;4.55,.52,;5.88,-.25,;7.21,.52,;7.21,2.06,;8.55,2.83,;9.88,2.06,;11.22,2.83,;12.55,2.06,;13.02,.59,;14.56,.59,;15.33,-.74,;15.04,2.06,;16.37,2.83,;13.79,2.96,;3.21,-.25,;3.21,-1.79,;1.88,-2.56,;.55,-1.79,;.55,-.25,;1.88,.52,;1.88,2.06,;-.79,.52,;-.79,2.06,;-2.12,2.83,;-3.46,2.06,;-3.46,.52,;-4.6,-.52,;-3.97,-1.92,;-2.44,-1.76,;-2.12,-.25,;-5.93,.25,;-7.27,-.52,;-7.27,-2.06,;-8.6,-2.83,;-8.6,-4.37,;-7.27,-5.14,;-9.93,-2.06,;-11.27,-2.83,;-12.6,-2.06,;-13,-.57,;-14.49,-.17,;-15.58,-1.26,;-15.18,-2.75,;-13.69,-3.14,;-14.49,-2.21,;-14.76,-1.19,;-14.89,1.32,;-16.37,1.72,;-13.8,2.41,;-9.93,-.52,;-8.6,.25,;-8.6,1.79,;-7.27,2.56,;-9.93,2.56,;-8.6,3.33,)|

BDBM461472

COc1nc(ccc1CNC[C@H]1C[C@H](O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(O)=O)nc1C(F)(F)F |r,wU:11.11,41.46,wD:28.36,13.14,(5.14,5.14,;6.47,4.37,;6.47,2.83,;5.14,2.06,;5.14,.52,;6.47,-.25,;7.8,.52,;7.8,2.06,;9.14,2.83,;10.47,2.06,;11.81,2.83,;13.14,2.06,;14.68,2.06,;14.68,.52,;16.01,-.25,;13.14,.52,;3.8,-.25,;3.8,-1.79,;2.47,-2.56,;1.14,-1.79,;1.14,-.25,;2.47,.52,;2.47,2.06,;-.2,.52,;-.2,2.06,;-1.53,2.83,;-2.87,2.06,;-2.87,.52,;-4.01,-.52,;-3.38,-1.92,;-1.85,-1.76,;-1.53,-.25,;-5.34,.25,;-6.68,-.52,;-6.68,-2.06,;-8.01,-2.83,;-8.01,-4.37,;-6.68,-5.14,;-9.34,-2.06,;-10.68,-2.83,;-12.01,-2.06,;-13.35,-2.83,;-14.11,-4.16,;-14.68,-2.06,;-16.01,-2.83,;-14.68,-.52,;-9.34,-.52,;-8.01,.25,;-8.01,1.79,;-6.68,2.56,;-9.34,2.56,;-8.01,3.33,)|

BDBM461473

COc1nc(ccc1CNC[C@H]1C[C@H](O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)nc1C(F)(F)F |r,wU:11.11,wD:28.36,13.14,(5.14,5.14,;6.47,4.37,;6.47,2.83,;5.14,2.06,;5.14,.52,;6.47,-.25,;7.8,.52,;7.8,2.06,;9.14,2.83,;10.47,2.06,;11.81,2.83,;13.14,2.06,;14.68,2.06,;14.68,.52,;16.01,-.25,;13.14,.52,;3.8,-.25,;3.8,-1.79,;2.47,-2.56,;1.14,-1.79,;1.14,-.25,;2.47,.52,;2.47,2.06,;-.2,.52,;-.2,2.06,;-1.53,2.83,;-2.87,2.06,;-2.87,.52,;-4.01,-.52,;-3.38,-1.92,;-1.85,-1.76,;-1.53,-.25,;-5.34,.25,;-6.68,-.52,;-6.68,-2.06,;-8.01,-2.83,;-8.01,-4.37,;-6.68,-5.14,;-9.34,-2.06,;-10.68,-2.83,;-12.01,-2.06,;-13.35,-2.83,;-14.68,-2.06,;-16.01,-2.83,;-14.68,-.52,;-9.34,-.52,;-8.01,.25,;-8.01,1.79,;-6.68,2.56,;-9.34,2.56,;-8.01,3.33,)|

BDBM461474

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(O)=O)nc1C(F)(F)F |r,wU:10.10,41.46,12.13,wD:28.36,12.14,(5.45,5.14,;6.78,4.37,;6.78,2.83,;5.45,2.06,;5.45,.52,;6.78,-.25,;8.11,.52,;8.11,2.06,;9.45,2.83,;10.78,2.06,;12.11,2.83,;12.88,4.16,;14.22,3.39,;15.31,4.48,;15.7,2.99,;13.45,2.06,;4.11,-.25,;4.11,-1.79,;2.78,-2.56,;1.44,-1.79,;1.44,-.25,;2.78,.52,;2.78,2.06,;.11,.52,;.11,2.06,;-1.22,2.83,;-2.56,2.06,;-2.56,.52,;-3.7,-.52,;-3.08,-1.92,;-1.54,-1.76,;-1.22,-.25,;-5.04,.25,;-6.37,-.52,;-6.37,-2.06,;-7.7,-2.83,;-7.7,-4.37,;-6.37,-5.14,;-9.04,-2.06,;-10.37,-2.83,;-11.7,-2.06,;-13.04,-2.83,;-13.81,-4.16,;-14.37,-2.06,;-15.7,-2.83,;-14.37,-.52,;-9.04,-.52,;-7.7,.25,;-7.7,1.79,;-6.37,2.56,;-9.04,2.56,;-7.7,3.33,)|

BDBM461475

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CCCC[C@]2(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461476

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CCCC[C@@]2(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461477

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC(C)(C1)C(O)=O)C(F)(F)F |r|

BDBM461478

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC(C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461479

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC(C1)C(O)=O)C(F)(F)F |r|

BDBM461480

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CCC3CC2(C3)C(O)=O)cc1C(F)(F)F |r,wD:27.35,TLB:38:39:43:45,(10.14,-1.27,;10.14,.27,;8.8,1.04,;7.47,.27,;6.14,1.04,;6.14,2.58,;7.47,3.35,;8.8,2.58,;10.14,3.35,;11.47,2.58,;11.87,1.09,;13.36,1.49,;14.9,1.49,;14.13,.15,;12.96,2.98,;4.8,.27,;4.8,-1.27,;3.47,-2.04,;2.14,-1.27,;2.14,.27,;3.47,1.04,;3.47,2.58,;.8,1.04,;.96,2.57,;-.28,3.47,;-1.69,2.85,;-1.85,1.32,;-3.1,.41,;-2.62,-1.05,;-1.08,-1.05,;-.6,.41,;-4.43,1.18,;-5.76,.41,;-5.76,-1.13,;-7.1,-1.9,;-7.1,-3.44,;-5.76,-4.21,;-8.43,-1.13,;-9.76,-1.9,;-11.1,-1.13,;-10.33,-2.46,;-11.81,-2.07,;-13.3,-2.46,;-12.9,-3.95,;-12.59,-1.52,;-14.07,-1.13,;-13.36,-.19,;-12.59,1.15,;-14.9,-.19,;-8.43,.41,;-7.1,1.18,;-7.1,2.72,;-5.76,3.49,;-8.43,3.49,;-6.7,4.21,)|

BDBM461481

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN1CC(C1)C(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,(-6.05,-4.99,;-7.39,-4.22,;-7.39,-2.68,;-6.05,-1.91,;-6.05,-.37,;-4.72,.4,;-3.39,-.37,;-2.91,-1.83,;-1.37,-1.83,;-.89,-.37,;-2.14,.54,;-1.98,2.07,;-.57,2.69,;.67,1.79,;.51,.26,;1.85,-.51,;1.85,-2.05,;3.18,-2.82,;4.51,-2.05,;4.51,-.51,;3.18,.26,;3.18,1.8,;5.85,.26,;5.85,1.8,;7.18,2.57,;8.51,1.8,;9.85,2.57,;11.18,1.8,;12.52,2.57,;12.91,4.05,;14.4,3.66,;15.17,4.99,;15.94,3.66,;14,2.17,;8.51,.26,;9.85,-.51,;9.85,-2.05,;7.18,-.51,;-7.39,.4,;-8.72,-.37,;-8.72,-1.91,;-10.05,-2.68,;-11.39,-1.91,;-11.79,-.42,;-13.27,-.82,;-12.88,-2.31,;-14.61,-.05,;-15.94,-.82,;-14.61,1.49,;-7.39,1.94,;-6.05,2.71,;-8.72,2.71,;-6.99,3.43,)|

BDBM461482

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN1CCC2CC1(C2)C(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,TLB:41:42:46:48,(-6.43,-4.99,;-7.76,-4.22,;-7.76,-2.68,;-6.43,-1.91,;-6.43,-.37,;-5.1,.4,;-3.76,-.37,;-3.29,-1.83,;-1.75,-1.83,;-1.27,-.37,;-2.52,.54,;-2.36,2.07,;-.95,2.69,;.3,1.79,;.14,.26,;1.47,-.51,;1.47,-2.05,;2.8,-2.82,;4.14,-2.05,;4.14,-.51,;2.8,.26,;2.8,1.8,;5.47,.26,;5.47,1.8,;6.8,2.57,;8.14,1.8,;9.47,2.57,;10.81,1.8,;12.14,2.57,;12.54,4.05,;14.02,3.66,;14.79,4.99,;15.56,3.66,;13.63,2.17,;8.14,.26,;9.47,-.51,;9.47,-2.05,;6.8,-.51,;-7.76,.4,;-9.1,-.37,;-9.1,-1.91,;-10.43,-2.68,;-11.77,-1.91,;-11,-3.24,;-12.48,-2.85,;-13.97,-3.24,;-13.57,-4.73,;-13.25,-2.3,;-14.74,-1.91,;-14.02,-.97,;-13.25,.37,;-15.56,-.97,;-7.76,1.94,;-6.43,2.71,;-9.1,2.71,;-7.37,3.43,)|

BDBM461483

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CCC3CC2(C3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:29.37,TLB:40:41:45:47,(8.6,-1.27,;8.6,.27,;7.27,1.04,;5.94,.27,;4.6,1.04,;4.6,2.58,;5.94,3.35,;7.27,2.58,;8.6,3.35,;9.94,2.58,;11.27,3.35,;12.61,2.58,;13.08,1.11,;14.62,1.11,;15.1,2.58,;16.43,3.35,;13.85,3.48,;3.27,.27,;3.27,-1.27,;1.94,-2.04,;.6,-1.27,;.6,.27,;1.94,1.04,;1.94,2.58,;-.73,1.04,;-.57,2.57,;-1.82,3.47,;-3.22,2.85,;-3.38,1.32,;-4.63,.41,;-4.15,-1.05,;-2.61,-1.05,;-2.14,.41,;-5.96,1.18,;-7.3,.41,;-7.3,-1.13,;-8.63,-1.9,;-8.63,-3.44,;-7.3,-4.21,;-9.96,-1.13,;-11.3,-1.9,;-12.63,-1.13,;-11.86,-2.46,;-13.34,-2.07,;-14.83,-2.46,;-14.43,-3.95,;-14.12,-1.52,;-15.6,-1.13,;-14.89,-.19,;-14.12,1.15,;-16.43,-.19,;-9.96,.41,;-8.63,1.18,;-8.63,2.72,;-7.3,3.49,;-9.96,3.49,;-8.23,4.21,)|

BDBM461484

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC(C)(O)C3)c(OC)n2)c(cc1CN1C2CCC1(CC2)C(O)=O)C(F)(F)F |r,TLB:40:41:44.43:46.47|

BDBM461485

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2C3CCC2(CC3)C(O)=O)cc1C(F)(F)F |r,TLB:40:41:44.43:46.47|

BDBM461486

COc1nc(ccc1CNC[C@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)nc1C(F)(F)F |r,wD:29.37,11.11,(8.04,-1.27,;8.04,.27,;6.71,1.04,;5.37,.27,;4.04,1.04,;4.04,2.58,;5.37,3.35,;6.71,2.58,;8.04,3.35,;9.37,2.58,;10.71,3.35,;12.04,2.58,;12.52,1.11,;14.06,1.11,;14.53,2.58,;15.87,3.35,;13.29,3.48,;2.7,.27,;2.7,-1.27,;1.37,-2.04,;.04,-1.27,;.04,.27,;1.37,1.04,;1.37,2.58,;-1.3,1.04,;-1.14,2.57,;-2.38,3.47,;-3.79,2.85,;-3.95,1.32,;-5.2,.41,;-4.72,-1.05,;-3.18,-1.05,;-2.7,.41,;-6.53,1.18,;-7.86,.41,;-7.86,-1.13,;-9.2,-1.9,;-9.2,-3.44,;-7.86,-4.21,;-10.53,-1.13,;-11.86,-1.9,;-13.2,-1.13,;-13.2,.41,;-14.53,1.18,;-15.87,.41,;-15.87,-1.13,;-14.53,-1.9,;-15.3,-.57,;-13.76,-.15,;-14.53,2.72,;-13.2,3.49,;-15.87,3.49,;-10.53,.41,;-9.2,1.18,;-9.2,2.72,;-7.86,3.49,;-10.53,3.49,;-8.8,4.21,)|

BDBM461487

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC(C)(O)C3)c(OC)n2)c(cc1CN[C@@H](C)C(O)=O)C(F)(F)F |r|

BDBM461488

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN[C@@H](C)C(O)=O)C(F)(F)F |r|

BDBM461489

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNCC(O)=O)C(F)(F)F |r|

BDBM461490

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN[C@@H](C)C(O)=O)C(F)(F)F |r,wU:28.30,43.49,30.33,wD:6.5,30.34,(-6.33,-4.99,;-7.66,-4.22,;-7.66,-2.68,;-6.33,-1.91,;-6.33,-.37,;-5,.4,;-3.66,-.37,;-3.19,-1.83,;-1.65,-1.83,;-1.17,-.37,;-2.42,.54,;-2.26,2.07,;-.85,2.69,;.4,1.79,;.24,.26,;1.57,-.51,;1.57,-2.05,;2.9,-2.82,;4.24,-2.05,;4.24,-.51,;2.9,.26,;2.9,1.8,;5.57,.26,;5.57,1.8,;6.9,2.57,;8.24,1.8,;9.57,2.57,;10.91,1.8,;12.24,2.57,;12.64,4.05,;14.13,3.66,;14.9,4.99,;15.67,3.66,;13.73,2.17,;8.24,.26,;9.57,-.51,;9.57,-2.05,;6.9,-.51,;-7.66,.4,;-9,-.37,;-9,-1.91,;-10.33,-2.68,;-11.66,-1.91,;-13,-2.68,;-13,-4.22,;-14.33,-1.91,;-15.67,-2.68,;-14.33,-.37,;-7.66,1.94,;-6.33,2.71,;-9,2.71,;-7.26,3.43,)|

BDBM461491

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)cc1C(F)(F)F |r,wU:10.10,12.13,wD:28.36,12.14,(9.57,-2.05,;9.57,-.51,;8.24,.26,;6.9,-.51,;5.57,.26,;5.57,1.8,;6.9,2.57,;8.24,1.8,;9.57,2.57,;10.91,1.8,;12.24,2.57,;12.64,4.05,;14.13,3.66,;14.9,4.99,;15.67,3.66,;13.73,2.17,;4.24,-.51,;4.24,-2.05,;2.9,-2.82,;1.57,-2.05,;1.57,-.51,;2.9,.26,;2.9,1.8,;.24,.26,;.4,1.79,;-.85,2.69,;-2.26,2.07,;-2.42,.54,;-3.66,-.37,;-3.19,-1.83,;-1.65,-1.83,;-1.17,-.37,;-5,.4,;-6.33,-.37,;-6.33,-1.91,;-7.66,-2.68,;-7.66,-4.22,;-6.33,-4.99,;-9,-1.91,;-10.33,-2.68,;-11.66,-1.91,;-13,-2.68,;-14.33,-1.91,;-15.67,-2.68,;-14.33,-.37,;-9,-.37,;-7.66,.4,;-7.66,1.94,;-6.33,2.71,;-9,2.71,;-7.26,3.43,)|

BDBM461492

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC[C@](C)(C2)C(O)=O)nc1C(F)(F)F |r|

BDBM461493

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2C3CCC2(CC3)C(O)=O)nc1C(F)(F)F |r|

BDBM461494

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CCC3CC2(C3)C(O)=O)nc1C(F)(F)F |r,wU:11.11,wD:29.37,(8.02,-1.3,;8.02,.24,;6.69,1.01,;5.36,.24,;4.02,1.01,;4.02,2.55,;5.36,3.32,;6.69,2.55,;8.02,3.32,;9.36,2.55,;10.69,3.32,;12.02,2.55,;12.02,1.01,;13.49,.54,;14.39,1.78,;15.88,2.18,;13.49,3.03,;2.69,.24,;2.69,-1.3,;1.35,-2.07,;.02,-1.3,;.02,.24,;1.35,1.01,;1.35,2.55,;-1.31,1.01,;-1.15,2.54,;-2.4,3.45,;-3.8,2.82,;-3.97,1.29,;-5.21,.38,;-4.74,-1.08,;-3.2,-1.08,;-2.72,.38,;-6.55,1.15,;-7.88,.38,;-7.88,-1.15,;-9.21,-1.93,;-9.21,-3.47,;-7.88,-4.23,;-10.55,-1.15,;-11.88,-1.93,;-13.21,-1.15,;-13.21,.38,;-14.55,1.16,;-15.88,.38,;-15.88,-1.15,;-14.55,-1.93,;-14.55,-.38,;-14.55,-3.47,;-13.21,-4.23,;-15.88,-4.23,;-10.55,.38,;-9.21,1.15,;-9.21,2.69,;-7.88,3.47,;-10.55,3.47,;-9.21,4.23,)|

BDBM461495

COc1nc(ccc1CN1CC[C@H](C1)C(O)=O)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC(C)(O)C2)nc1C(F)(F)F |r|

BDBM461496

COc1nc(ccc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(O)=O)nc1C(F)(F)F |r|

BDBM461497

COc1nc(ccc1CN1CC(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)nc1C(F)(F)F |r|

BDBM461498

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(O)=O)nc1C(F)(F)F |r|

BDBM461499

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)nc1C(F)(F)F |r|

BDBM461500

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2C[C@H](C)C[C@H]2C(O)=O)nc1C(F)(F)F |r|

BDBM461501

CCC1C(CCN1Cc1nc(c(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r|

BDBM461502

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2C[C@H](C)C[C@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461503

CCC1C(CCN1Cc1cc(c(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r|

BDBM461504

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2C[C@@H]3CC[C@H]2[C@@H]3C(O)=O)nc1C(F)(F)F |r,TLB:48:47:42.41:44.45|

BDBM461505

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN2CC3CC2C(C3)C(O)=O)nc1C(F)(F)F |r|

BDBM461506

COC(=O)C12CCC(CC1)N(Cc1nc(c(N[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc1OC)C(F)(F)F)C2 |r,THB:11:10:6.5:8.9|

BDBM461507

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN[C@@H](C)C(O)=O)C(F)(F)F |r,wU:29.31,31.34,44.50,wD:6.5,31.35,(-6.96,-5.14,;-8.29,-4.37,;-8.29,-2.83,;-6.96,-2.06,;-6.96,-.52,;-5.63,.25,;-4.29,-.52,;-3.66,-1.92,;-2.13,-1.76,;-1.81,-.25,;-3.15,.52,;-3.15,2.06,;-1.81,2.83,;-.48,2.06,;-.48,.52,;.85,-.25,;.85,-1.79,;2.19,-2.56,;3.52,-1.79,;3.52,-.25,;2.19,.52,;2.19,2.06,;4.86,.52,;6.19,-.25,;7.52,.52,;7.52,2.06,;8.86,2.83,;10.19,2.06,;11.52,2.83,;12.86,2.06,;14.19,2.83,;14.96,1.49,;16.29,2.26,;15.36,0,;13.63,.72,;6.19,2.83,;6.19,4.37,;4.86,5.14,;4.86,2.06,;-8.29,.25,;-9.63,-.52,;-9.63,-2.06,;-10.96,-2.83,;-12.29,-2.06,;-13.63,-2.83,;-13.63,-4.37,;-14.96,-2.06,;-16.29,-2.83,;-14.96,-.52,;-8.29,1.79,;-6.96,2.56,;-9.63,2.56,;-8.29,3.33,)|

BDBM461508

COc1nc(ccc1CNC[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)cc1C(F)(F)F |r,wU:11.11,13.14,wD:29.37,13.15,(4.86,5.14,;6.19,4.37,;6.19,2.83,;4.86,2.06,;4.86,.52,;6.19,-.25,;7.52,.52,;7.52,2.06,;8.86,2.83,;10.19,2.06,;11.52,2.83,;12.86,2.06,;14.19,2.83,;14.96,1.49,;16.29,2.26,;15.36,0,;13.63,.72,;3.52,-.25,;3.52,-1.79,;2.19,-2.56,;.85,-1.79,;.85,-.25,;2.19,.52,;2.19,2.06,;-.48,.52,;-.48,2.06,;-1.81,2.83,;-3.15,2.06,;-3.15,.52,;-4.29,-.52,;-3.67,-1.92,;-2.13,-1.76,;-1.81,-.25,;-5.63,.25,;-6.96,-.52,;-6.96,-2.06,;-8.29,-2.83,;-8.29,-4.37,;-6.96,-5.14,;-9.63,-2.06,;-10.96,-2.83,;-12.29,-2.06,;-13.63,-2.83,;-14.96,-2.06,;-16.29,-2.83,;-14.96,-.52,;-9.63,-.52,;-8.29,.25,;-8.29,1.79,;-6.96,2.56,;-9.63,2.56,;-8.29,3.33,)|

BDBM461509

COc1nc(ccc1CNC[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNC2(CC2)C(O)=O)nc1C(F)(F)F |r,wU:11.11,13.14,wD:29.37,13.15,(4.86,5.14,;6.19,4.37,;6.19,2.83,;4.86,2.06,;4.86,.52,;6.19,-.25,;7.52,.52,;7.52,2.06,;8.86,2.83,;10.19,2.06,;11.52,2.83,;12.86,2.06,;14.19,2.83,;14.96,1.49,;16.29,2.26,;15.36,0,;13.63,.72,;3.52,-.25,;3.52,-1.79,;2.19,-2.56,;.85,-1.79,;.85,-.25,;2.19,.52,;2.19,2.06,;-.48,.52,;-.48,2.06,;-1.81,2.83,;-3.15,2.06,;-3.15,.52,;-4.29,-.52,;-3.67,-1.92,;-2.13,-1.76,;-1.81,-.25,;-5.63,.25,;-6.96,-.52,;-6.96,-2.06,;-8.29,-2.83,;-8.29,-4.37,;-6.96,-5.14,;-9.63,-2.06,;-10.96,-2.83,;-12.29,-2.06,;-13.63,-2.83,;-14.4,-4.16,;-12.86,-4.16,;-14.96,-2.06,;-16.29,-2.83,;-14.96,-.52,;-9.63,-.52,;-8.29,.25,;-8.29,1.79,;-6.96,2.56,;-9.63,2.56,;-8.29,3.33,)|

BDBM461510

COc1nc(ccc1CNC[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(O)=O)nc1C(F)(F)F |r,wU:11.11,13.14,42.47,wD:29.37,13.15,(4.86,5.14,;6.19,4.37,;6.19,2.83,;4.86,2.06,;4.86,.52,;6.19,-.25,;7.52,.52,;7.52,2.06,;8.86,2.83,;10.19,2.06,;11.52,2.83,;12.86,2.06,;14.19,2.83,;14.96,1.49,;16.29,2.26,;15.36,0,;13.63,.72,;3.52,-.25,;3.52,-1.79,;2.19,-2.56,;.85,-1.79,;.85,-.25,;2.19,.52,;2.19,2.06,;-.48,.52,;-.48,2.06,;-1.81,2.83,;-3.15,2.06,;-3.15,.52,;-4.29,-.52,;-3.67,-1.92,;-2.13,-1.76,;-1.81,-.25,;-5.63,.25,;-6.96,-.52,;-6.96,-2.06,;-8.29,-2.83,;-8.29,-4.37,;-6.96,-5.14,;-9.63,-2.06,;-10.96,-2.83,;-12.29,-2.06,;-13.63,-2.83,;-13.63,-4.37,;-14.96,-2.06,;-16.29,-2.83,;-14.96,-.52,;-9.63,-.52,;-8.29,.25,;-8.29,1.79,;-6.96,2.56,;-9.63,2.56,;-8.29,3.33,)|

BDBM461511

COc1nc(ccc1CNC[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)nc1C(F)(F)F |r,wU:11.11,13.14,wD:29.37,13.15,(4.86,5.14,;6.19,4.37,;6.19,2.83,;4.86,2.06,;4.86,.52,;6.19,-.25,;7.52,.52,;7.52,2.06,;8.86,2.83,;10.19,2.06,;11.52,2.83,;12.86,2.06,;14.19,2.83,;14.96,1.49,;16.29,2.26,;15.36,0,;13.63,.72,;3.52,-.25,;3.52,-1.79,;2.19,-2.56,;.85,-1.79,;.85,-.25,;2.19,.52,;2.19,2.06,;-.48,.52,;-.48,2.06,;-1.81,2.83,;-3.15,2.06,;-3.15,.52,;-4.29,-.52,;-3.67,-1.92,;-2.13,-1.76,;-1.81,-.25,;-5.63,.25,;-6.96,-.52,;-6.96,-2.06,;-8.29,-2.83,;-8.29,-4.37,;-6.96,-5.14,;-9.63,-2.06,;-10.96,-2.83,;-12.29,-2.06,;-13.63,-2.83,;-14.96,-2.06,;-16.29,-2.83,;-14.96,-.52,;-9.63,-.52,;-8.29,.25,;-8.29,1.79,;-6.96,2.56,;-9.63,2.56,;-8.29,3.33,)|

BDBM461512

CNC(=O)CNCc1nc(c(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F |r|

BDBM461513

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CNCCC(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,(-5.59,-5.14,;-6.93,-4.37,;-6.93,-2.83,;-5.59,-2.06,;-5.59,-.52,;-4.26,.25,;-2.93,-.52,;-2.3,-1.92,;-.77,-1.76,;-.45,-.25,;-1.78,.52,;-1.78,2.06,;-.45,2.83,;.89,2.06,;.89,.52,;2.22,-.25,;2.22,-1.79,;3.55,-2.56,;4.89,-1.79,;4.89,-.25,;3.55,.52,;3.55,2.06,;6.22,.52,;7.55,-.25,;8.89,.52,;8.89,2.06,;10.22,2.83,;11.56,2.06,;12.89,2.83,;13.29,4.31,;14.78,3.91,;15.86,5,;16.26,3.52,;14.38,2.43,;7.55,2.83,;7.55,4.37,;6.22,5.14,;6.22,2.06,;-6.93,.25,;-8.26,-.52,;-8.26,-2.06,;-9.59,-2.83,;-10.93,-2.06,;-12.26,-2.83,;-13.6,-2.06,;-14.93,-2.83,;-16.26,-2.06,;-14.93,-4.37,;-6.93,1.79,;-5.59,2.56,;-8.26,2.56,;-6.93,3.33,)|

BDBM461514

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C2CC2)C(O)=O)cc1C(F)(F)F |r,wU:41.45,10.10,12.13,wD:28.36,12.14,(5.55,5.42,;6.89,4.65,;6.89,3.11,;5.55,2.34,;5.55,.8,;6.89,.03,;8.22,.8,;8.22,2.34,;9.55,3.11,;10.89,2.34,;12.22,3.11,;12.62,4.59,;14.11,4.2,;15.2,5.28,;15.6,3.8,;13.71,2.71,;4.22,.03,;4.22,-1.51,;2.89,-2.28,;1.55,-1.51,;1.55,.03,;2.89,.8,;2.89,2.34,;.22,.8,;.22,2.34,;-1.11,3.11,;-2.45,2.34,;-2.45,.8,;-3.59,-.23,;-2.97,-1.64,;-1.43,-1.48,;-1.11,.03,;-4.93,.54,;-6.26,-.23,;-6.26,-1.77,;-7.59,-2.54,;-7.59,-4.08,;-6.26,-4.85,;-8.93,-1.77,;-10.26,-2.54,;-11.59,-1.77,;-12.93,-2.54,;-12.93,-4.08,;-13.7,-5.42,;-12.16,-5.42,;-14.26,-1.77,;-15.6,-2.54,;-14.26,-.23,;-8.93,-.23,;-7.59,.54,;-7.59,2.08,;-6.26,2.85,;-8.93,2.85,;-7.59,3.62,)|

BDBM461515

COC[C@H](NCc1cc(c(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r,wU:3.3,33.35,35.38,wD:11.10,35.39,(-13.7,-5.98,;-12.93,-4.65,;-13.7,-3.31,;-12.93,-1.98,;-11.59,-1.21,;-10.26,-1.98,;-8.93,-1.21,;-8.93,.33,;-7.59,1.1,;-6.26,.33,;-4.93,1.1,;-3.59,.33,;-2.97,-1.08,;-1.43,-.92,;-1.11,.59,;-2.45,1.36,;-2.45,2.9,;-1.11,3.67,;.22,2.9,;.22,1.36,;1.55,.59,;1.55,-.95,;2.89,-1.72,;4.22,-.95,;4.22,.59,;2.89,1.36,;2.89,2.9,;5.55,1.36,;6.89,.59,;8.22,1.36,;8.22,2.9,;9.55,3.67,;10.89,2.9,;12.22,3.67,;12.62,5.16,;14.11,4.76,;15.2,5.85,;15.6,4.36,;13.71,3.27,;6.89,3.67,;6.89,5.21,;5.55,5.98,;5.55,2.9,;-6.26,-1.21,;-7.59,-1.98,;-7.59,-3.52,;-6.26,-4.29,;-7.59,2.64,;-6.26,3.41,;-8.93,3.41,;-7.59,4.18,;-14.26,-1.21,;-15.6,-1.98,;-14.26,.33,)|

BDBM461516

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNC(C)(C)C(O)=O)cc1C(F)(F)F |r,wU:10.10,12.13,wD:28.36,12.14,(5.55,5.14,;6.89,4.37,;6.89,2.83,;5.55,2.06,;5.55,.52,;6.89,-.25,;8.22,.52,;8.22,2.06,;9.55,2.83,;10.89,2.06,;12.22,2.83,;12.62,4.31,;14.11,3.91,;15.2,5,;15.6,3.52,;13.71,2.43,;4.22,-.25,;4.22,-1.79,;2.89,-2.56,;1.55,-1.79,;1.55,-.25,;2.89,.52,;2.89,2.06,;.22,.52,;.22,2.06,;-1.11,2.83,;-2.45,2.06,;-2.45,.52,;-3.59,-.52,;-2.97,-1.92,;-1.43,-1.76,;-1.11,-.25,;-4.93,.25,;-6.26,-.52,;-6.26,-2.06,;-7.59,-2.83,;-7.59,-4.37,;-6.26,-5.14,;-8.93,-2.06,;-10.26,-2.83,;-11.59,-2.06,;-12.93,-2.83,;-13.7,-4.16,;-12.16,-4.16,;-14.26,-2.06,;-15.6,-2.83,;-14.26,-.52,;-8.93,-.52,;-7.59,.25,;-7.59,1.79,;-6.26,2.56,;-8.93,2.56,;-7.59,3.33,)|

BDBM461517

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCCC(O)=O)nc1C(F)(F)F |r,wU:10.10,12.13,wD:28.36,12.14,(6.22,5.14,;7.55,4.37,;7.55,2.83,;6.22,2.06,;6.22,.52,;7.55,-.25,;8.89,.52,;8.89,2.06,;10.22,2.83,;11.56,2.06,;12.89,2.83,;13.29,4.31,;14.78,3.91,;15.86,5,;16.26,3.52,;14.38,2.43,;4.89,-.25,;4.89,-1.79,;3.55,-2.56,;2.22,-1.79,;2.22,-.25,;3.55,.52,;3.55,2.06,;.89,.52,;.89,2.06,;-.45,2.83,;-1.78,2.06,;-1.78,.52,;-2.93,-.52,;-2.3,-1.92,;-.77,-1.76,;-.45,-.25,;-4.26,.25,;-5.59,-.52,;-5.59,-2.06,;-6.93,-2.83,;-6.93,-4.37,;-5.59,-5.14,;-8.26,-2.06,;-9.59,-2.83,;-10.93,-2.06,;-12.26,-2.83,;-13.6,-2.06,;-14.93,-2.83,;-16.26,-2.06,;-14.93,-4.37,;-8.26,-.52,;-6.93,.25,;-6.93,1.79,;-5.59,2.56,;-8.26,2.56,;-6.93,3.33,)|

BDBM461518

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C2CC2)C(O)=O)nc1C(F)(F)F |r,wU:41.45,10.10,12.13,wD:28.36,12.14,(5.55,5.42,;6.89,4.65,;6.89,3.11,;5.55,2.34,;5.55,.8,;6.89,.03,;8.22,.8,;8.22,2.34,;9.55,3.11,;10.89,2.34,;12.22,3.11,;12.62,4.59,;14.11,4.2,;15.2,5.28,;15.6,3.8,;13.71,2.71,;4.22,.03,;4.22,-1.51,;2.89,-2.28,;1.55,-1.51,;1.55,.03,;2.89,.8,;2.89,2.34,;.22,.8,;.22,2.34,;-1.11,3.11,;-2.45,2.34,;-2.45,.8,;-3.59,-.23,;-2.97,-1.64,;-1.43,-1.48,;-1.11,.03,;-4.93,.54,;-6.26,-.23,;-6.26,-1.77,;-7.59,-2.54,;-7.59,-4.08,;-6.26,-4.85,;-8.93,-1.77,;-10.26,-2.54,;-11.59,-1.77,;-12.93,-2.54,;-12.93,-4.08,;-13.7,-5.42,;-12.16,-5.42,;-14.26,-1.77,;-15.6,-2.54,;-14.26,-.23,;-8.93,-.23,;-7.59,.54,;-7.59,2.08,;-6.26,2.85,;-8.93,2.85,;-7.59,3.62,)|

BDBM461519

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNC(C)(C)C(O)=O)nc1C(F)(F)F |r,wU:10.10,12.13,wD:28.36,12.14,(5.55,5.14,;6.89,4.37,;6.89,2.83,;5.55,2.06,;5.55,.52,;6.89,-.25,;8.22,.52,;8.22,2.06,;9.55,2.83,;10.89,2.06,;12.22,2.83,;12.62,4.31,;14.11,3.91,;15.2,5,;15.6,3.52,;13.71,2.43,;4.22,-.25,;4.22,-1.79,;2.89,-2.56,;1.55,-1.79,;1.55,-.25,;2.89,.52,;2.89,2.06,;.22,.52,;.22,2.06,;-1.11,2.83,;-2.45,2.06,;-2.45,.52,;-3.59,-.52,;-2.97,-1.92,;-1.43,-1.76,;-1.11,-.25,;-4.93,.25,;-6.26,-.52,;-6.26,-2.06,;-7.59,-2.83,;-7.59,-4.37,;-6.26,-5.14,;-8.93,-2.06,;-10.26,-2.83,;-11.59,-2.06,;-12.93,-2.83,;-13.7,-4.16,;-12.16,-4.16,;-14.26,-2.06,;-15.6,-2.83,;-14.26,-.52,;-8.93,-.52,;-7.59,.25,;-7.59,1.79,;-6.26,2.56,;-8.93,2.56,;-7.59,3.33,)|

BDBM461520

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN(C)[C@@H](C)C(O)=O)nc1C(F)(F)F |r|

BDBM461521

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(=O)N(C)C)nc1C(F)(F)F |r|

BDBM461522

COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN[C@@H](C)C(N)=O)C(F)(F)F |r|

BDBM461523

COC(=O)[C@H](C)NCc1nc(c(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F |r|

BDBM461524

COC[C@H](NCc1nc(c(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r|

BDBM461525

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C2CC2)C(O)=O)nc1C(F)(F)F |r|

BDBM461526

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(N)=O)nc1C(F)(F)F |r|

BDBM461527

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(N)=O)nc1C(F)(F)F |r|

BDBM461528

CC[C@H](NCc1nc(c(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r|

BDBM461529

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C(C)C)C(O)=O)nc1C(F)(F)F |r|

BDBM461530

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CN[C@@H](C)C(O)=O)nc1C(F)(F)F |r|

BDBM461531

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)nc1C(F)(F)F |r|

BDBM461532

COc1cc(ccc1CNC1CC(O)(CF)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)nc1C(F)(F)F |r,wD:29.37,(9.14,-1.85,;9.14,-.31,;7.81,.46,;6.48,-.31,;5.14,.46,;5.14,2,;6.48,2.77,;7.81,2,;9.14,2.77,;10.48,2,;11.81,2.77,;13.3,2.37,;13.7,3.86,;14.47,5.19,;15.24,3.86,;16.01,2.52,;12.21,4.26,;3.81,-.31,;3.81,-1.85,;2.48,-2.62,;1.14,-1.85,;1.14,-.31,;2.48,.46,;2.48,2,;-.19,.46,;-.19,2,;-1.53,2.77,;-2.86,2,;-2.86,.46,;-4,-.57,;-3.38,-1.98,;-1.85,-1.82,;-1.53,-.31,;-5.34,.2,;-6.67,-.57,;-6.67,-2.11,;-8.01,-2.88,;-8.01,-4.42,;-9.34,-5.19,;-9.34,-2.11,;-10.67,-2.88,;-12.01,-2.11,;-13.34,-2.88,;-14.67,-2.11,;-16.01,-2.88,;-14.67,-.57,;-9.34,-.57,;-8.01,.2,;-8.01,1.74,;-6.67,2.51,;-9.34,2.51,;-8.01,3.28,)|

BDBM461533

COc1nc(ccc1CN[C@@H]1CCCC[C@@H]1O)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Nc1nc(OC)c(CNCC(O)=O)nc1C(F)(F)F |r|

BDBM461534

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC(C)(C)C(O)=O)cc1C(F)(F)F |r,wU:10.10,12.13,wD:28.36,12.14,(5.45,5.14,;6.78,4.37,;6.78,2.83,;5.45,2.06,;5.45,.52,;6.78,-.25,;8.11,.52,;8.11,2.06,;9.45,2.83,;10.78,2.06,;12.11,2.83,;12.88,4.16,;14.22,3.39,;15.31,4.48,;15.7,2.99,;13.45,2.06,;4.11,-.25,;4.11,-1.79,;2.78,-2.56,;1.44,-1.79,;1.44,-.25,;2.78,.52,;2.78,2.06,;.11,.52,;.11,2.06,;-1.22,2.83,;-2.56,2.06,;-2.56,.52,;-3.7,-.52,;-3.08,-1.92,;-1.54,-1.76,;-1.22,-.25,;-5.04,.25,;-6.37,-.52,;-6.37,-2.06,;-7.7,-2.83,;-7.7,-4.37,;-6.37,-5.14,;-9.04,-2.06,;-10.37,-2.83,;-11.7,-2.06,;-13.04,-2.83,;-13.81,-4.16,;-12.27,-4.16,;-14.37,-2.06,;-15.7,-2.83,;-14.37,-.52,;-9.04,-.52,;-7.7,.25,;-7.7,1.79,;-6.37,2.56,;-9.04,2.56,;-7.7,3.33,)|

BDBM461535

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN1CC[C@H](C1)C(O)=O)C(F)(F)F |r,wU:28.30,30.33,45.53,wD:6.5,30.34,(-6.77,-5.14,;-8.1,-4.37,;-8.1,-2.83,;-6.77,-2.06,;-6.77,-.52,;-5.44,.25,;-4.1,-.52,;-3.48,-1.92,;-1.95,-1.76,;-1.63,-.25,;-2.96,.52,;-2.96,2.06,;-1.63,2.83,;-.29,2.06,;-.29,.52,;1.04,-.25,;1.04,-1.79,;2.38,-2.56,;3.71,-1.79,;3.71,-.25,;2.38,.52,;2.38,2.06,;5.04,.52,;6.38,-.25,;7.71,.52,;7.71,2.06,;9.04,2.83,;10.38,2.06,;11.71,2.83,;12.48,4.16,;13.82,3.39,;14.9,4.48,;15.3,2.99,;13.05,2.06,;6.38,2.83,;6.38,4.37,;5.04,5.14,;5.04,2.06,;-8.1,.25,;-9.44,-.52,;-9.44,-2.06,;-10.77,-2.83,;-12.11,-2.06,;-13.57,-2.53,;-14.48,-1.29,;-13.57,-.04,;-12.11,-.52,;-13.97,1.45,;-13.2,2.78,;-15.3,2.22,;-8.1,1.79,;-6.77,2.56,;-9.44,2.56,;-8.1,3.33,)|

BDBM461536

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN1CC[C@@H]2C[C@]12C(O)=O)C(F)(F)F |r,wU:28.30,30.33,45.51,wD:6.5,30.34,47.55,(-6.87,-5,;-8.2,-4.23,;-8.2,-2.69,;-6.87,-1.92,;-6.87,-.38,;-5.54,.39,;-4.2,-.38,;-3.58,-1.79,;-2.05,-1.63,;-1.73,-.12,;-3.06,.65,;-3.06,2.19,;-1.73,2.96,;-.39,2.19,;-.39,.65,;.94,-.12,;.94,-1.66,;2.28,-2.43,;3.61,-1.66,;3.61,-.12,;2.28,.65,;2.28,2.19,;4.94,.65,;6.28,-.12,;7.61,.65,;7.61,2.19,;8.94,2.96,;10.28,2.19,;11.61,2.96,;12.38,4.29,;13.71,3.52,;14.8,4.61,;15.2,3.13,;12.94,2.19,;6.28,2.96,;6.28,4.5,;4.94,5.27,;4.94,2.19,;-8.2,.39,;-9.54,-.38,;-9.54,-1.92,;-10.87,-2.69,;-12.21,-1.92,;-12.21,-.38,;-13.67,.1,;-14.58,-1.15,;-15.2,-2.56,;-13.67,-2.4,;-13.67,-3.94,;-12.34,-4.71,;-14.44,-5.27,;-8.2,1.93,;-6.66,1.93,;-9.74,1.93,;-8.2,3.47,)|

BDBM461537

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN1CC2(CCC1CC2)C(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,(-6.48,-5.14,;-7.82,-4.37,;-7.82,-2.83,;-6.48,-2.06,;-6.48,-.52,;-5.15,.25,;-3.82,-.52,;-3.19,-1.92,;-1.66,-1.76,;-1.34,-.25,;-2.67,.52,;-2.67,2.06,;-1.34,2.83,;-0,2.06,;-0,.52,;1.33,-.25,;1.33,-1.79,;2.66,-2.56,;4,-1.79,;4,-.25,;2.66,.52,;2.66,2.06,;5.33,.52,;6.66,-.25,;8,.52,;8,2.06,;9.33,2.83,;10.67,2.06,;12,2.83,;12.77,4.16,;14.1,3.39,;15.19,4.48,;15.59,2.99,;13.33,2.06,;6.66,2.83,;6.66,4.37,;5.33,5.14,;5.33,2.06,;-7.82,.25,;-9.15,-.52,;-9.15,-2.06,;-10.48,-2.83,;-11.82,-2.06,;-12.22,-.57,;-13.7,-.17,;-14.79,-1.26,;-14.39,-2.75,;-12.91,-3.14,;-13.7,-2.21,;-13.98,-1.19,;-14.1,1.32,;-15.59,1.72,;-13.01,2.41,;-7.82,1.79,;-6.28,1.79,;-9.36,1.79,;-7.82,3.33,)|

BDBM461538

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461539

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461540

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C)[C@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461541

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@]2(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461542

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C2C)C(O)=O)cc1Cl |r|

BDBM461543

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C)(C2)C(O)=O)cc1Cl |r|

BDBM461544

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC2CCC(C2)(C1)C(O)=O |r|

BDBM461545

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC(C)(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461546

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@@]2(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461547

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(Cl)cc1CNC1(CC1)C(O)=O |r|

BDBM461548

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC2(CCOCC2)C(O)=O)cc1Cl |r|

BDBM461549

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@@H]2C(O)=O)cc1Cl |r|

BDBM461550

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@@]2(C)C(O)=O)cc1Cl |r|

BDBM461551

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@H]2C(O)=O)cc1Cl |r|

BDBM461552

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461553

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CNC12CC(C1)(C2)C(O)=O |r|

BDBM461554

CNc1nc(cnc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461555

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCC#N)c(CNC2(CC2)C(O)=O)cc1C(F)(F)F |r|

BDBM461556

COc1nc(ccc1CNC1CC2CCC1N2C(C)=O)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wD:32.41,THB:17:16:10.11:13.14,(4.63,4.41,;5.96,3.64,;5.96,2.1,;4.63,1.33,;4.63,-.21,;5.96,-.98,;7.3,-.21,;7.3,1.33,;8.63,2.1,;9.96,1.33,;11.3,2.1,;12.63,1.33,;13.97,2.1,;13.97,3.64,;12.63,4.41,;11.3,3.64,;12.88,3.19,;13.65,4.52,;15.19,4.52,;12.88,5.86,;3.3,-.98,;3.3,-2.52,;1.96,-3.29,;.63,-2.52,;.63,-.98,;1.96,-.21,;1.96,1.33,;-.71,-.21,;-.71,1.33,;-2.04,2.1,;-3.37,1.33,;-3.37,-.21,;-4.52,-1.24,;-3.89,-2.65,;-2.36,-2.48,;-2.04,-.98,;-5.85,-.47,;-7.18,-1.24,;-7.18,-2.78,;-8.52,-3.55,;-8.52,-5.09,;-7.18,-5.86,;-9.85,-2.78,;-11.19,-3.55,;-12.52,-2.78,;-12.52,-1.24,;-13.85,-.47,;-15.19,-1.24,;-15.19,-2.78,;-13.85,-3.55,;-13.32,-2.44,;-13.32,-1.39,;-13.85,1.07,;-15.19,1.84,;-12.52,1.84,;-9.85,-1.24,;-8.52,-.47,;-8.52,1.07,)|

BDBM461557

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CC(C3)C(O)=O)C2)cc1Cl |r|

BDBM461558

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC(C)(C)C(C2)C(O)=O)cc1Cl |r|

BDBM461559

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC3(CC23)C(O)=O)cc1Cl |r|

BDBM461560

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CNCCC(O)=O |r|

BDBM461561

CNC(=O)C1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3cnc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc2OC)C1 |r|

BDBM461562

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cncc(Cl)c2)c(CNC2(CC2)C(O)=O)cc1C(F)(F)F |r|

BDBM461563

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cc(F)cc(c2)C#N)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(8.17,2.2,;8.17,3.74,;6.84,4.51,;5.5,3.74,;4.17,4.51,;4.17,6.05,;5.5,6.82,;6.84,6.05,;8.17,6.82,;9.5,6.05,;10.84,6.82,;12.17,6.05,;12.17,4.51,;13.64,4.04,;14.54,5.28,;16.08,5.28,;13.64,6.53,;2.84,3.74,;2.84,2.2,;1.5,1.43,;.17,2.2,;.17,3.74,;1.5,4.51,;1.5,6.05,;-1.17,4.51,;-1.17,6.05,;-2.5,6.82,;-3.83,6.05,;-3.83,4.51,;-4.98,3.48,;-4.35,2.08,;-2.82,2.24,;-2.5,3.74,;-6.47,3.88,;-7.55,2.79,;-7.16,1.3,;-8.24,.22,;-7.85,-1.27,;-6.36,-1.67,;-5.96,-3.16,;-7.05,-4.25,;-6.65,-5.73,;-7.74,-6.82,;-5.16,-6.13,;-4.07,-5.04,;-4.47,-3.56,;-2.59,-5.44,;-1.1,-5.84,;-9.73,.61,;-10.82,-.47,;-12.31,-.08,;-12.71,1.41,;-14.19,1.81,;-15.28,.72,;-14.89,-.77,;-13.4,-1.16,;-14.49,-.08,;-13.11,.72,;-14.59,3.3,;-16.08,3.7,;-13.5,4.39,;-10.13,2.1,;-9.04,3.19,;-9.44,4.68,)|

BDBM461564

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cc(Cl)cc(c2)C#N)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(8.17,2.2,;8.17,3.74,;6.84,4.51,;5.5,3.74,;4.17,4.51,;4.17,6.05,;5.5,6.82,;6.84,6.05,;8.17,6.82,;9.5,6.05,;10.84,6.82,;12.17,6.05,;12.17,4.51,;13.64,4.04,;14.54,5.28,;16.08,5.28,;13.64,6.53,;2.84,3.74,;2.84,2.2,;1.5,1.43,;.17,2.2,;.17,3.74,;1.5,4.51,;1.5,6.05,;-1.17,4.51,;-1.17,6.05,;-2.5,6.82,;-3.83,6.05,;-3.83,4.51,;-4.98,3.48,;-4.35,2.08,;-2.82,2.24,;-2.5,3.74,;-6.47,3.88,;-7.55,2.79,;-7.16,1.3,;-8.24,.22,;-7.85,-1.27,;-6.36,-1.67,;-5.96,-3.16,;-7.05,-4.25,;-6.65,-5.73,;-7.74,-6.82,;-5.16,-6.13,;-4.07,-5.04,;-4.47,-3.56,;-2.59,-5.44,;-1.1,-5.84,;-9.73,.61,;-10.82,-.47,;-12.31,-.08,;-12.71,1.41,;-14.19,1.81,;-15.28,.72,;-14.89,-.77,;-13.4,-1.16,;-14.49,-.08,;-13.11,.72,;-14.59,3.3,;-16.08,3.7,;-13.5,4.39,;-10.13,2.1,;-9.04,3.19,;-9.44,4.68,)|

BDBM461565

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cncc(Cl)c2)c(CNC2(CC2)C(O)=O)cc1Cl |r|

BDBM461566

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cncc(F)c2)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(8.17,1.86,;8.17,3.4,;6.84,4.17,;5.5,3.4,;4.17,4.17,;4.17,5.71,;5.5,6.48,;6.84,5.71,;8.17,6.48,;9.5,5.71,;10.84,6.48,;12.17,5.71,;12.17,4.17,;13.64,3.69,;14.54,4.94,;16.08,4.94,;13.64,6.18,;2.84,3.4,;2.84,1.86,;1.5,1.09,;.17,1.86,;.17,3.4,;1.5,4.17,;1.5,5.71,;-1.17,4.17,;-1.17,5.71,;-2.5,6.48,;-3.83,5.71,;-3.83,4.17,;-4.98,3.14,;-4.35,1.73,;-2.82,1.89,;-2.5,3.4,;-6.47,3.54,;-7.55,2.45,;-7.16,.96,;-8.24,-.13,;-7.85,-1.62,;-6.36,-2.02,;-5.96,-3.5,;-7.05,-4.59,;-6.65,-6.08,;-5.16,-6.48,;-4.07,-5.39,;-2.59,-5.79,;-4.47,-3.9,;-9.73,.27,;-10.82,-.82,;-12.31,-.42,;-12.71,1.07,;-14.19,1.46,;-15.28,.38,;-14.89,-1.11,;-13.4,-1.51,;-14.49,-.42,;-13.11,.38,;-14.59,2.95,;-16.08,3.35,;-13.5,4.04,;-10.13,1.76,;-9.04,2.85,;-9.44,4.33,)|

BDBM461567

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CNC1CC(C1)NC(C)=O |r,wU:29.31,wD:6.5,(-5.59,-5.14,;-6.92,-4.37,;-6.92,-2.83,;-5.59,-2.06,;-5.59,-.52,;-4.25,.25,;-2.92,-.52,;-2.29,-1.92,;-.76,-1.76,;-.44,-.25,;-1.77,.52,;-1.77,2.06,;-.44,2.83,;.89,2.06,;.89,.52,;2.23,-.25,;2.23,-1.79,;3.56,-2.56,;4.9,-1.79,;4.9,-.25,;3.56,.52,;3.56,2.06,;6.23,.52,;7.56,-.25,;8.9,.52,;8.9,2.06,;10.23,2.83,;11.56,2.06,;12.9,2.83,;14.23,2.06,;14.23,.52,;15.7,.04,;16.6,1.29,;18.14,1.29,;15.7,2.53,;7.56,2.83,;7.56,4.37,;6.23,5.14,;6.23,2.06,;-6.92,.25,;-6.92,1.79,;-8.25,-.52,;-8.25,-2.06,;-9.59,-2.83,;-10.92,-2.06,;-12.25,-2.83,;-13.74,-2.43,;-14.14,-3.91,;-12.65,-4.31,;-15.47,-4.68,;-16.81,-3.91,;-18.14,-4.68,;-16.81,-2.37,)|

BDBM461568

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC2(CCC2)C(O)=O)cc1Cl |r|

BDBM461569

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC2(CC2)C(O)=O)cc1C(F)(F)F |r|

BDBM461570

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)nc1Br |r|

BDBM461571

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC[C@@H]2CCC(=O)N2)nc1Br |r|

BDBM461572

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;1.28,.52,;1.28,2.06,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-14,-1.72,;-14,-.66,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,)|

BDBM461573

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC(F)F)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(8.17,.37,;8.17,1.91,;6.84,2.68,;5.5,1.91,;4.17,2.68,;4.17,4.22,;5.5,4.99,;6.84,4.22,;8.17,4.99,;9.5,4.22,;10.84,4.99,;12.17,4.22,;12.17,2.68,;13.64,2.2,;14.54,3.45,;16.08,3.45,;13.64,4.7,;2.84,1.91,;2.84,.37,;1.5,-.4,;.17,.37,;.17,1.91,;1.5,2.68,;1.5,4.22,;-1.17,2.68,;-1.17,4.22,;-2.5,4.99,;-3.83,4.22,;-3.83,2.68,;-4.98,1.65,;-4.35,.24,;-2.82,.4,;-2.5,1.91,;-6.47,2.05,;-7.55,.96,;-7.16,-.53,;-8.24,-1.62,;-7.85,-3.1,;-6.36,-3.5,;-5.96,-4.99,;-5.27,-2.41,;-9.73,-1.22,;-10.82,-2.31,;-12.31,-1.91,;-12.71,-.42,;-14.19,-.02,;-15.28,-1.11,;-14.88,-2.6,;-13.4,-3,;-14.49,-1.91,;-13.11,-1.11,;-14.59,1.46,;-16.08,1.86,;-13.5,2.55,;-10.13,.27,;-9.04,1.36,;-9.44,2.85,)|

BDBM461574

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461575

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C2)C(O)=O)cc1Cl |r|

BDBM461576

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC(C1)C(O)=O |r|

BDBM461577

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)nc1CN1CC(C1)C(O)=O |r|

BDBM461578

COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)nc1Cl |r,wU:11.11,wD:29.37,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;1.28,.52,;1.28,2.06,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-13.76,-1.49,;-15.3,-1.08,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,)|

BDBM461579

CCOc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC2(CCC1CC2)C(O)=O |r,wU:30.32,wD:7.6,(-5.96,-4.99,;-6.36,-3.5,;-7.85,-3.1,;-8.24,-1.62,;-7.16,-.53,;-7.55,.96,;-6.47,2.05,;-4.98,1.65,;-4.35,.24,;-2.82,.4,;-2.5,1.91,;-3.83,2.68,;-3.83,4.22,;-2.5,4.99,;-1.17,4.22,;-1.17,2.68,;.17,1.91,;.17,.37,;1.5,-.4,;2.84,.37,;2.84,1.91,;1.5,2.68,;1.5,4.22,;4.17,2.68,;4.17,4.22,;5.5,4.99,;6.84,4.22,;8.17,4.99,;9.5,4.22,;10.84,4.99,;12.17,4.22,;12.17,2.68,;13.64,2.2,;14.54,3.45,;16.08,3.45,;13.64,4.7,;6.84,2.68,;8.17,1.91,;8.17,.37,;5.5,1.91,;-9.04,1.36,;-9.44,2.85,;-10.13,.27,;-9.73,-1.22,;-10.82,-2.31,;-12.31,-1.91,;-12.71,-.42,;-14.19,-.02,;-15.28,-1.11,;-14.89,-2.6,;-13.4,-3,;-14.49,-1.91,;-13.11,-1.11,;-14.59,1.46,;-16.08,1.86,;-13.5,2.55,)|

BDBM461580

CCOc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@@H](C1)C(O)=O |r|

BDBM461581

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cncc(Cl)c2)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(8.17,1.86,;8.17,3.4,;6.84,4.17,;5.5,3.4,;4.17,4.17,;4.17,5.71,;5.5,6.48,;6.84,5.71,;8.17,6.48,;9.5,5.71,;10.84,6.48,;12.17,5.71,;12.17,4.17,;13.64,3.69,;14.54,4.94,;16.08,4.94,;13.64,6.18,;2.84,3.4,;2.84,1.86,;1.5,1.09,;.17,1.86,;.17,3.4,;1.5,4.17,;1.5,5.71,;-1.17,4.17,;-1.17,5.71,;-2.5,6.48,;-3.83,5.71,;-3.83,4.17,;-4.98,3.14,;-4.35,1.73,;-2.82,1.89,;-2.5,3.4,;-6.47,3.54,;-7.55,2.45,;-7.16,.96,;-8.24,-.13,;-7.85,-1.62,;-6.36,-2.02,;-5.96,-3.5,;-7.05,-4.59,;-6.65,-6.08,;-5.16,-6.48,;-4.07,-5.39,;-2.59,-5.79,;-4.47,-3.9,;-9.73,.27,;-10.82,-.82,;-12.31,-.42,;-12.71,1.07,;-14.19,1.46,;-15.28,.38,;-14.89,-1.11,;-13.4,-1.51,;-14.49,-.42,;-13.11,.38,;-14.59,2.95,;-16.08,3.35,;-13.5,4.04,;-10.13,1.76,;-9.04,2.85,;-9.44,4.33,)|

BDBM461582

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cncc(Cl)c2)c(CN2CC[C@@H](C2)C(O)=O)cc1Cl |r|

BDBM461583

COc1nc(ccc1CN[C@H]1CCCC[C@H]1O)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wD:29.37,10.10,15.17,(5.24,5.14,;6.57,4.37,;6.57,2.83,;5.24,2.06,;5.24,.52,;6.57,-.25,;7.91,.52,;7.91,2.06,;9.24,2.83,;10.57,2.06,;11.91,2.83,;13.24,2.06,;14.58,2.83,;14.58,4.37,;13.24,5.14,;11.91,4.37,;10.57,5.14,;3.91,-.25,;3.91,-1.79,;2.57,-2.56,;1.24,-1.79,;1.24,-.25,;2.57,.52,;2.57,2.06,;-.09,.52,;-.09,2.06,;-1.43,2.83,;-2.76,2.06,;-2.76,.52,;-3.91,-.52,;-3.28,-1.92,;-1.75,-1.76,;-1.43,-.25,;-5.24,.25,;-6.57,-.52,;-6.57,-2.06,;-7.91,-2.83,;-7.91,-4.37,;-6.57,-5.14,;-9.24,-2.06,;-10.57,-2.83,;-11.91,-2.06,;-11.91,-.52,;-13.24,.25,;-14.58,-.52,;-14.58,-2.06,;-13.24,-2.83,;-13.77,-1.72,;-13.77,-.66,;-13.24,1.79,;-14.58,2.56,;-11.91,2.56,;-9.24,-.52,;-7.91,.25,;-7.91,1.79,)|

BDBM461584

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC[C@@H](O)C3)c(OC)n2)c(Cl)cc1CN1CC2(CCC1CC2)C(O)=O |r,wU:30.33,wD:6.5,(-5.76,-5.14,;-7.09,-4.37,;-7.09,-2.83,;-5.76,-2.06,;-5.76,-.52,;-4.42,.25,;-3.09,-.52,;-2.46,-1.92,;-.93,-1.76,;-.61,-.25,;-1.95,.52,;-1.95,2.06,;-.61,2.83,;.72,2.06,;.72,.52,;2.05,-.25,;2.05,-1.79,;3.39,-2.56,;4.72,-1.79,;4.72,-.25,;3.39,.52,;3.39,2.06,;6.06,.52,;7.39,-.25,;8.72,.52,;8.72,2.06,;10.06,2.83,;11.39,2.06,;12.85,2.53,;13.76,1.29,;12.85,.04,;13.25,-1.45,;11.39,.52,;7.39,2.83,;7.39,4.37,;6.06,5.14,;6.06,2.06,;-7.09,.25,;-7.09,1.79,;-8.43,-.52,;-8.43,-2.06,;-9.76,-2.83,;-11.09,-2.06,;-11.09,-.52,;-12.43,.25,;-13.76,-.52,;-13.76,-2.06,;-12.43,-2.83,;-12.96,-1.72,;-12.96,-.66,;-12.43,1.79,;-13.76,2.56,;-11.09,2.56,)|

BDBM461585

COc1nc(ccc1CN[C@@H]1CCC[C@@H]1O)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:10.10,14.16,wD:28.36,(5.39,5.14,;6.72,4.37,;6.72,2.83,;5.39,2.06,;5.39,.52,;6.72,-.25,;8.06,.52,;8.06,2.06,;9.39,2.83,;10.72,2.06,;12.06,2.83,;13.52,2.35,;14.43,3.6,;13.52,4.84,;12.06,4.37,;10.72,5.14,;4.06,-.25,;4.06,-1.79,;2.72,-2.56,;1.39,-1.79,;1.39,-.25,;2.72,.52,;2.72,2.06,;.05,.52,;.05,2.06,;-1.28,2.83,;-2.61,2.06,;-2.61,.52,;-3.76,-.52,;-3.13,-1.92,;-1.6,-1.76,;-1.28,-.25,;-5.09,.25,;-6.43,-.52,;-6.43,-2.06,;-7.76,-2.83,;-7.76,-4.37,;-6.43,-5.14,;-9.09,-2.06,;-10.43,-2.83,;-11.76,-2.06,;-11.76,-.52,;-13.09,.25,;-14.43,-.52,;-14.43,-2.06,;-13.09,-2.83,;-13.62,-1.72,;-13.62,-.66,;-13.09,1.79,;-14.43,2.56,;-11.76,2.56,;-9.09,-.52,;-7.76,.25,;-7.76,1.79,)|

BDBM461586

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@@H]2CCC[C@@H]2C(O)=O)cc1Cl |r|

BDBM461587

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CNC1(CC1)C(O)=O |r|

BDBM461588

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCC#N)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(8.17,1.11,;8.17,2.65,;6.84,3.42,;5.5,2.65,;4.17,3.42,;4.17,4.96,;5.5,5.73,;6.84,4.96,;8.17,5.73,;9.5,4.96,;10.84,5.73,;12.17,4.96,;12.17,3.42,;13.64,2.95,;14.54,4.19,;16.08,4.19,;13.64,5.44,;2.84,2.65,;2.84,1.11,;1.5,.34,;.17,1.11,;.17,2.65,;1.5,3.42,;1.5,4.96,;-1.17,3.42,;-1.17,4.96,;-2.5,5.73,;-3.83,4.96,;-3.83,3.42,;-4.98,2.39,;-4.35,.99,;-2.82,1.15,;-2.5,2.65,;-6.47,2.79,;-7.55,1.7,;-7.16,.22,;-8.24,-.87,;-7.85,-2.36,;-6.36,-2.76,;-5.96,-4.25,;-5.56,-5.73,;-9.73,-.47,;-10.82,-1.56,;-12.31,-1.16,;-12.71,.32,;-14.19,.72,;-15.28,-.37,;-14.89,-1.86,;-13.4,-2.25,;-14.49,-1.16,;-13.11,-.37,;-14.59,2.21,;-16.08,2.61,;-13.5,3.3,;-10.13,1.01,;-9.04,2.1,;-9.44,3.59,)|

BDBM461589

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2ccc(nc2)-n2cccn2)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(8.17,3.85,;8.17,5.39,;6.84,6.16,;5.5,5.39,;4.17,6.16,;4.17,7.7,;5.5,8.47,;6.84,7.7,;8.17,8.47,;9.5,7.7,;10.84,8.47,;12.17,7.7,;12.17,6.16,;13.64,5.68,;14.54,6.93,;16.08,6.93,;13.64,8.17,;2.84,5.39,;2.84,3.85,;1.5,3.08,;.17,3.85,;.17,5.39,;1.5,6.16,;1.5,7.7,;-1.17,6.16,;-1.17,7.7,;-2.5,8.47,;-3.83,7.7,;-3.83,6.16,;-4.98,5.13,;-4.35,3.72,;-2.82,3.88,;-2.5,5.39,;-6.47,5.53,;-7.55,4.44,;-7.16,2.95,;-8.24,1.86,;-7.85,.37,;-6.36,-.03,;-5.96,-1.51,;-7.05,-2.6,;-6.65,-4.09,;-5.16,-4.49,;-4.07,-3.4,;-4.47,-1.91,;-4.76,-5.98,;-3.3,-6.45,;-3.3,-7.99,;-4.76,-8.47,;-5.67,-7.22,;-9.73,2.26,;-10.82,1.17,;-12.31,1.57,;-12.71,3.06,;-14.19,3.45,;-15.28,2.37,;-14.88,.88,;-13.4,.48,;-14.49,1.57,;-13.11,2.37,;-14.59,4.94,;-16.08,5.34,;-13.5,6.03,;-10.13,3.75,;-9.04,4.84,;-9.44,6.32,)|

BDBM461590

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CN3CC(C)(O)C3)c(OC)n2)c(Cl)cc1CN1CC2(CCC1CC2)C(O)=O |r,wD:6.5,(-6.26,-4.75,;-7.59,-3.98,;-7.59,-2.44,;-6.26,-1.67,;-6.26,-.13,;-4.93,.64,;-3.59,-.13,;-2.97,-1.54,;-1.43,-1.38,;-1.11,.13,;-2.45,.9,;-2.45,2.44,;-1.11,3.21,;.22,2.44,;.22,.9,;1.55,.13,;1.55,-1.41,;2.89,-2.18,;4.22,-1.41,;4.22,.13,;2.89,.9,;2.89,2.44,;5.55,.9,;5.55,2.44,;6.89,3.21,;6.89,4.75,;8.22,2.44,;9.55,3.21,;10.89,2.44,;11.29,.95,;12.77,1.35,;13.17,-.14,;14.26,1.75,;12.38,2.84,;8.22,.9,;9.55,.13,;9.55,-1.41,;6.89,.13,;-7.59,.64,;-7.59,2.18,;-8.93,-.13,;-8.93,-1.67,;-10.26,-2.44,;-11.59,-1.67,;-11.59,-.13,;-12.93,.64,;-14.26,-.13,;-14.26,-1.67,;-12.93,-2.44,;-12.53,-1.3,;-13.7,-.69,;-12.93,2.18,;-14.26,2.95,;-11.59,2.95,)|

BDBM461591

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CN3CC(C)(O)C3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461592

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CN3CC(C)(O)C3)c(OC)n2)c(Cl)cc1CN1CC(C1)C(O)=O |r|

BDBM461593

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CN3CC(C)(O)C3)c(OC)n2)c(Cl)cc1CN1CC[C@@H](C1)C(O)=O |r|

BDBM461594

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:29.37,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;1.28,.52,;1.28,2.06,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-14,-1.72,;-14,-.66,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,;-10.53,2.56,;-7.86,2.56,;-9.2,3.33,)|

BDBM461595

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461596

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC(C1)C(O)=O)C(F)(F)F |r|

BDBM461597

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC(C2)NC(C)=O)cc1Cl |r|

BDBM461598

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cncc(c2)C#N)c(CN2CC[C@@H](C2)C(O)=O)cc1Cl |r|

BDBM461599

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cncc(c2)C#N)c(CN2CC[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461600

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OCc2cncc(c2)C#N)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(8.17,1.86,;8.17,3.4,;6.84,4.17,;5.5,3.4,;4.17,4.17,;4.17,5.71,;5.5,6.48,;6.84,5.71,;8.17,6.48,;9.5,5.71,;10.84,6.48,;12.17,5.71,;12.17,4.17,;13.64,3.69,;14.54,4.94,;16.08,4.94,;13.64,6.18,;2.84,3.4,;2.84,1.86,;1.5,1.09,;.17,1.86,;.17,3.4,;1.5,4.17,;1.5,5.71,;-1.17,4.17,;-1.17,5.71,;-2.5,6.48,;-3.83,5.71,;-3.83,4.17,;-4.98,3.14,;-4.35,1.73,;-2.82,1.89,;-2.5,3.4,;-6.47,3.54,;-7.55,2.45,;-7.16,.96,;-8.24,-.13,;-7.85,-1.62,;-6.36,-2.02,;-5.96,-3.5,;-7.05,-4.59,;-6.65,-6.08,;-5.16,-6.48,;-4.07,-5.39,;-4.47,-3.9,;-2.59,-5.79,;-1.1,-6.19,;-9.73,.27,;-10.82,-.82,;-12.31,-.42,;-12.71,1.07,;-14.19,1.46,;-15.28,.38,;-14.88,-1.11,;-13.4,-1.51,;-14.49,-.42,;-13.11,.38,;-14.59,2.95,;-16.08,3.35,;-13.5,4.04,;-10.13,1.76,;-9.04,2.85,;-9.44,4.33,)|

BDBM461601

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(-c2cccc3[C@H](CCc23)Oc2nc(OC)c(CN3CC4(CCC3CC4)C(O)=O)cc2Cl)c1C#N |r,wU:11.11,wD:27.34,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-14,-1.72,;-14,-.66,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,;1.28,.52,;1.28,2.06,;1.28,3.6,)|

BDBM461602

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(-c3cnc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)c2C#N)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461603

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC(C(O)=O)C2(CCOC2)C1 |r|

BDBM461604

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C(O)=O)C3(CCC3)C2)cc1Cl |r|

BDBM461605

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C(O)=O)C3(CC3)C2)cc1Cl |r|

BDBM461606

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(-c2cccc3[C@H](CCc23)Oc2nc(OC)c(CN3CC[C@H](C3)C(O)=O)cc2Cl)c1C#N |r|

BDBM461607

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)c2C#N)c(Cl)cc1CN1CC(C1)C(O)=O |r|

BDBM461608

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC(C)(O)C3)c(OC)n2)c(Cl)cc1CN1CC(C1)C(=O)NS(C)(=O)=O |r|

BDBM461609

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(=O)NS(C)(=O)=O)cc1Cl |r|

BDBM461610

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1C)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;1.28,.52,;1.28,2.06,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-14,-1.72,;-14,-.66,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,)|

BDBM461611

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1C)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461612

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cnc([C@@H](C)NC[C@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461613

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2C)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC2(CCC1CC2)C(O)=O |r,wU:29.31,wD:6.5,(-7.86,-5.14,;-9.2,-4.37,;-9.2,-2.83,;-7.86,-2.06,;-7.86,-.52,;-6.53,.25,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-4.05,.52,;-4.05,2.06,;-2.72,2.83,;-1.38,2.06,;-1.38,.52,;-.05,-.25,;-.05,-1.79,;1.28,-2.56,;2.62,-1.79,;2.62,-.25,;1.28,.52,;1.28,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;5.29,2.83,;5.29,4.37,;3.95,5.14,;3.95,2.06,;-9.2,.25,;-9.2,1.79,;-10.53,-.52,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-14,-1.72,;-14,-.66,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,)|

BDBM461614

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2C)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461615

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CCN(C)C(C1)C(O)=O |r|

BDBM461616

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@@H]3CCC[C@@]3(C2)C(O)=O)cc1Cl |r|

BDBM461617

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@@H](C1)C(=O)NS(C)(=O)=O |r|

BDBM461618

COc1nc(ccc1CN1CC(C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461619

CNC(=O)C1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CN4CC(C)(O)C4)c(OC)n3)nc2OC)C1 |r|

BDBM461620

CNC(=O)C1CCN(Cc2ccc(nc2OC)-c2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2nc(OC)c(CN3CCC(C3)C(=O)NC)cc2Cl)C1 |r|

BDBM461621

CNC(=O)C1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc2OC)C1 |r|

BDBM461622

CNC(=O)CCNCc1ccc(nc1OC)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNCCC(=O)NC)cc1Cl |r|

BDBM461623

CNC(=O)CCNCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC |r|

BDBM461624

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cnc([C@H](C)NC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461625

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1C[C@@H]2CCC[C@@]2(C1)C(O)=O |r|

BDBM461626

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@@H]3CC[C@@]3(C2)C(O)=O)cc1Cl |r|

BDBM461627

COC(=O)[C@@H]1[C@H]2CN(Cc3cc(Cl)c(O[C@H]4CCc5c4cccc5-c4cccc(c4Cl)-c4ccc(CNC[C@@H]5CCC(=O)N5)c(OC)n4)nc3OC)C[C@@H]12 |r|

BDBM461628

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@@H]3C[C@@]3(C2)C(O)=O)cc1Cl |r|

BDBM461629

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)cn2)c(Cl)cc1CN1CC(C1)C(O)=O |r|

BDBM461630

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)cn2)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461631

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3CCC2C(C3)C(O)=O)cc1Cl |r|

BDBM461632

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3CC3(C2)C(O)=O)cc1Cl |r|

BDBM461633

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC(C)(O)C3)c(OC)n2)c(Cl)cc1CN1CC(C1)C(O)=O |r|

BDBM461634

CNC(=O)C1CN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc2OC)C1 |r|

BDBM461635

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC(C)(O)C1 |r|

BDBM461636

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CSc12)Oc1nc(OC)c(CNC[C@@H]2CCC(=O)N2)cc1Cl |r|

BDBM461637

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(O)C2)cc1Cl |r|

BDBM461638

CCOC(=O)C1CN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc2OC)C1 |r|

BDBM461639

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@H](C)[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461640

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@@H](C)[C@@H](C2)C(O)=O)cc1Cl |r|

BDBM461641

COC(=O)[C@@H]1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc2OC)C1 |r|

BDBM461642

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CCC[C@H](C1)C(=O)NS(C)(=O)=O |r|

BDBM461643

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C2)C(=O)NS(=O)(=O)C(F)F)cc1Cl |r|

BDBM461644

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(=O)NS(=O)(=O)C(F)F |r|

BDBM461645

CCS(=O)(=O)NC(=O)[C@@H]1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc2OC)C1 |r|

BDBM461646

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(=O)NS(C)(=O)=O |r|

BDBM461647

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@@H](C2)C(O)=O)cc1Cl |r|

BDBM461648

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC(CC2)C(O)=O)cc1Cl |r|

BDBM461649

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(Cl)c2)c(Cl)cc1CNC1(CC1)C(O)=O |r|

BDBM461650

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@@H]3C[C@]23C(O)=O)cc1C(F)(F)F |r|

BDBM461651

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@@]2(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461652

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(cc1C(F)(F)F)C(C)N1CC(C1)C(O)=O |r|

BDBM461653

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(cc1C(F)(F)F)C(C)NCCC(O)=O |r|

BDBM461654

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC(C)(C)C(O)=O)cc1C(F)(F)F |r|

BDBM461655

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC2(CC2)C(O)=O)cc1C(F)(F)F |r|

BDBM461656

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CN3CC(C(O)=O)C4(CC4)C3)c(OC)n2)c(Cl)cc1CNC[C@@H]1CCC(=O)N1 |r|

BDBM461657

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CN3C[C@H]4[C@@H](C3)[C@@H]4C(O)=O)c(OC)n2)c(Cl)cc1CNC[C@@H]1CCC(=O)N1 |r|

BDBM461658

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461659

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(cc1CN1CC2(CCC1CC2)C(O)=O)C(F)(F)F |r,wU:29.31,wD:6.5,(-7.86,-6.68,;-9.2,-5.91,;-9.2,-4.37,;-7.86,-3.6,;-7.86,-2.06,;-6.53,-1.29,;-5.19,-2.06,;-4.57,-3.46,;-3.04,-3.3,;-2.72,-1.79,;-4.05,-1.02,;-4.05,.52,;-2.72,1.29,;-1.38,.52,;-1.38,-1.02,;-.05,-1.79,;-.05,-3.33,;1.28,-4.1,;2.62,-3.33,;2.62,-1.79,;1.28,-1.02,;1.28,.52,;3.95,-1.02,;5.29,-1.79,;6.62,-1.02,;6.62,.52,;7.95,1.29,;9.29,.52,;10.62,1.29,;11.95,.52,;11.95,-1.02,;13.42,-1.5,;14.32,-.25,;15.86,-.25,;13.42,.99,;5.29,1.29,;5.29,2.83,;3.95,3.6,;3.95,5.14,;3.95,6.68,;3.95,.52,;-9.2,-1.29,;-10.53,-2.06,;-10.53,-3.6,;-11.86,-4.37,;-13.2,-3.6,;-13.2,-2.06,;-14.53,-1.29,;-15.86,-2.06,;-15.86,-3.6,;-14.53,-4.37,;-13.76,-3.03,;-15.3,-2.62,;-14.53,.25,;-15.86,1.02,;-13.2,1.02,;-9.2,.25,;-10.53,1.02,;-7.86,1.02,;-9.2,1.79,)|

BDBM461660

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OCC#N)n2)c(cc1CN1CC[C@H](C1)C(O)=O)C(F)(F)F |r|

BDBM461661

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC2(CC2)C(O)=O)cc1Cl |r|

BDBM461662

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1Cl |r,wU:12.12,wD:30.38,(7.95,-1.41,;7.95,.13,;6.62,.9,;5.29,.13,;3.95,.9,;3.95,2.44,;5.29,3.21,;5.29,4.75,;6.62,2.44,;7.95,3.21,;9.29,2.44,;10.62,3.21,;11.95,2.44,;11.95,.9,;13.42,.42,;14.32,1.67,;15.86,1.67,;13.42,2.92,;2.62,.13,;2.62,-1.41,;1.28,-2.18,;-.05,-1.41,;-.05,.13,;1.28,.9,;1.28,2.44,;-1.38,.9,;-1.38,2.44,;-2.72,3.21,;-4.05,2.44,;-4.05,.9,;-5.19,-.13,;-4.57,-1.54,;-3.04,-1.38,;-2.72,.13,;-6.53,.64,;-7.86,-.13,;-7.86,-1.67,;-9.2,-2.44,;-9.2,-3.98,;-7.86,-4.75,;-10.53,-1.67,;-11.86,-2.44,;-13.2,-1.67,;-13.2,-.13,;-14.53,.64,;-15.86,-.13,;-15.86,-1.67,;-14.53,-2.44,;-15.06,-1.34,;-15.06,-.28,;-14.53,2.18,;-13.2,2.95,;-15.86,2.95,;-10.53,-.13,;-9.2,.64,;-9.2,2.18,)|

BDBM461663

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C2)C(O)=O)cc1Cl |r|

BDBM461664

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461665

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CN3C[C@@H]4C[C@@]4(C3)C(O)=O)c(OC)n2)c(Cl)cc1CNC[C@@H]1CCC(=O)N1 |r|

BDBM461666

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CN3CC[C@H](C3)C(O)=O)c(OC)n2)c(Cl)cc1CNC[C@@H]1CCC(=O)N1 |r|

BDBM461667

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3CCC2(CC3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:29.37,(7.77,.66,;7.77,2.2,;6.44,2.97,;5.1,2.2,;3.77,2.97,;3.77,4.51,;5.1,5.28,;6.44,4.51,;7.77,5.28,;9.11,4.51,;10.44,5.28,;11.77,4.51,;11.77,2.97,;13.24,2.5,;14.14,3.74,;15.68,3.74,;13.24,4.99,;2.44,2.2,;2.44,.66,;1.1,-.11,;-.23,.66,;-.23,2.2,;1.1,2.97,;1.1,4.51,;-1.56,2.97,;-1.56,4.51,;-2.9,5.28,;-4.23,4.51,;-4.23,2.97,;-5.38,1.94,;-4.75,.53,;-3.22,.7,;-2.9,2.2,;-6.86,2.34,;-7.95,1.25,;-7.55,-.24,;-8.64,-1.32,;-8.24,-2.81,;-6.76,-3.21,;-10.13,-.93,;-11.22,-2.02,;-12.71,-1.62,;-13.11,-.13,;-14.59,.27,;-15.68,-.82,;-15.28,-2.31,;-13.8,-2.71,;-14.88,-1.62,;-13.5,-.82,;-13.4,-4.19,;-11.91,-4.59,;-14.49,-5.28,;-10.53,.56,;-9.44,1.65,;-9.84,3.14,;-8.75,4.23,;-11.33,3.54,;-10.24,4.63,)|

BDBM461668

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CCCC[C@@]1(C)C(O)=O)C(F)(F)F |r|

BDBM461669

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2[C@@H]3C[C@@H]3C[C@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461670

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2[C@H]3C[C@H]3C[C@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461671

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@@H]3C[C@@H]3[C@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461672

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CNC1(CC2CCC1C2)C(O)=O |r|

BDBM461673

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:29.37,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;1.28,.52,;1.28,2.06,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-14,-1.72,;-14,-.66,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,;-10.74,1.79,;-7.66,1.79,;-9.2,3.33,)|

BDBM461674

COc1cc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C)(C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461675

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(F)c(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC(C1)C(O)=O |r|

BDBM461676

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)c2F)c(Cl)cc1CN1CC[C@H](C1)C(O)=O |r|

BDBM461677

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CC3)C[C@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461678

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3CC2(C3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:29.37,(7.57,.44,;7.57,1.98,;6.24,2.75,;4.91,1.98,;3.57,2.75,;3.57,4.29,;4.91,5.06,;6.24,4.29,;7.57,5.06,;8.91,4.29,;10.24,5.06,;11.57,4.29,;11.57,2.75,;13.04,2.27,;13.94,3.52,;15.48,3.52,;13.04,4.76,;2.24,1.98,;2.24,.44,;.91,-.33,;-.43,.44,;-.43,1.98,;.91,2.75,;.91,4.29,;-1.76,2.75,;-1.76,4.29,;-3.1,5.06,;-4.43,4.29,;-4.43,2.75,;-5.57,1.72,;-4.95,.31,;-3.42,.47,;-3.1,1.98,;-7.06,2.12,;-8.15,1.03,;-7.75,-.46,;-8.84,-1.55,;-8.44,-3.04,;-6.95,-3.44,;-10.33,-1.15,;-11.42,-2.24,;-12.9,-1.84,;-13.38,-.38,;-14.92,-.38,;-15.4,-1.84,;-14.15,-2.75,;-13.75,-1.26,;-14.15,-4.29,;-15.48,-5.06,;-12.82,-5.06,;-10.73,.34,;-9.64,1.42,;-10.04,2.91,;-8.95,4,;-11.52,3.31,;-10.44,4.4,)|

BDBM461679

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc2n(C)nc(CN3CC4(C3)CNC(=O)C4)c2nc1Cl |r|

BDBM461680

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc2n(C)nc(CNC[C@@H]3CCC(=O)N3)c2nc1Cl |r|

BDBM461681

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C2)C(O)=O)nc1C |r|

BDBM461682

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)nc1C |r,wU:11.11,wD:29.37,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;1.28,.52,;1.28,2.06,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-13.76,-1.49,;-15.3,-1.08,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,)|

BDBM461683

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)nc1C |r|

BDBM461684

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC[C@@H]2CCC(=O)N2)nc1C |r|

BDBM461685

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC(C2)C(O)=O)nc1Cl |r|

BDBM461686

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)nc1Cl |r,wU:11.11,wD:29.37,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;1.28,.52,;1.28,2.06,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-13.76,-1.49,;-15.3,-1.08,;-14.53,1.79,;-15.86,2.56,;-13.2,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,)|

BDBM461687

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)nc1Cl |r|

BDBM461688

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC[C@@H]2CCC(=O)N2)nc1Cl |r|

BDBM461689

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1cnc(CN2CC[C@H](C2)C(O)=O)c(OC)n1 |r|

BDBM461690

COC(=O)[C@@H]1CCN(Cc2ncc(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc2OC)C1 |r|

BDBM461691

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CCC(CC1)C(=O)N=S(C)(N)=O |r|

BDBM461692

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC(C1)C(=O)N=S(C)(=O)NC(C)=O |r|

BDBM461693

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(=O)N=S(C)(=O)N(CC(F)(F)F)CC(F)(F)F |r|

BDBM461694

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(=O)N=S(C)(=O)NCC(F)(F)F |r|

BDBM461695

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(=O)N=S(C)(=O)NC(=O)C(F)(F)F)cc1Cl |r|

BDBM461696

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(=O)N=S(C)(=O)NC(C)=O)cc1Cl |r|

BDBM461697

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@H](C1)C(=O)N=S(C)(N)=O |r|

BDBM461698

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC[C@@H](C1)C(O)=O)C(F)(F)F |r|

BDBM461699

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC2(CCC1CC2)C(O)=O |r,wU:29.31,wD:6.5,(-7.23,-5.14,;-8.57,-4.37,;-8.57,-2.83,;-7.23,-2.06,;-7.23,-.52,;-5.9,.25,;-4.57,-.52,;-3.94,-1.92,;-2.41,-1.76,;-2.09,-.25,;-3.42,.52,;-3.42,2.06,;-2.09,2.83,;-.75,2.06,;-.75,.52,;.58,-.25,;.58,-1.79,;1.91,-2.56,;3.25,-1.79,;3.25,-.25,;1.91,.52,;1.91,2.06,;4.58,.52,;5.92,-.25,;7.25,.52,;7.25,2.06,;8.58,2.83,;9.92,2.06,;11.25,2.83,;12.58,2.06,;12.58,.52,;14.05,.04,;14.95,1.29,;16.49,1.29,;14.05,2.53,;5.92,2.83,;5.92,4.37,;4.58,5.14,;4.58,2.06,;-8.57,.25,;-8.57,1.79,;-9.9,-.52,;-9.9,-2.06,;-11.23,-2.83,;-12.72,-2.43,;-13.12,-.94,;-14.61,-.54,;-15.7,-1.63,;-15.3,-3.12,;-13.81,-3.52,;-14.61,-2.59,;-14.88,-1.56,;-15.01,.95,;-16.49,1.35,;-13.92,2.04,)|

BDBM461700

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC[C@@H](C1)C(O)=O |r|

BDBM461701

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC4(C3)CN(C4)C(C)=O)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461702

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC4(C3)CNC(=O)C4)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461703

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC4(C3)CCC(=O)N4)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461704

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC(C)(O)C3)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461705

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@@H]3C[C@]23C(O)=O)cc1Cl |r|

BDBM461706

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN(C)CC(O)=O)cc1Cl |r|

BDBM461707

[H]C12CCC([H])(C1C(O)=O)N(Cc1cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(c3Cl)-c3ccc(CNC[C@@H]4CCC(=O)N4)c(OC)n3)nc1OC)C2 |r,THB:7:6:3.2:10.55|

BDBM461708

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@@H](C)[C@H]2C(O)=O)cc1Cl |r|

BDBM461709

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CCCCC(C1)C(O)=O |r|

BDBM461710

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CCCC(CC1)C(O)=O |r|

BDBM461711

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC(C)(CC2)C(O)=O)cc1Cl |r|

BDBM461712

CCN(CC(O)=O)Cc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(F)c(CNC[C@@H]3CCC(=O)N3)c(OC)c2)nc1OC)C(F)(F)F |r|

BDBM461713

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@H]3C[C@@]2([C@H]3C)C(O)=O)cc1Cl |r|

BDBM461714

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC2CC1(CCC2)C(O)=O |r|

BDBM461715

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@H]3[C@@H]([C@H]2C(O)=O)C3(C)C)cc1Cl |r|

BDBM461716

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC(C)(C)[C@H]2C(O)=O)cc1Cl |r|

BDBM461717

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(Cl)cc1CN1CC2CC1C(C2)C(O)=O |r|

BDBM461718

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@H](C)C[C@H]2C(O)=O)cc1Cl |r|

BDBM461719

CCC1C(CCN1Cc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(O)=O |r|

BDBM461720

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN(C)CC(O)=O)cc1C(F)(F)F |r|

BDBM461721

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(F)c(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC[C@@H](C1)C(O)=O)C(F)(F)F |r|

BDBM461722

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(F)c(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461723

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(F)c(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC2(CCC1CC2)C(O)=O)C(F)(F)F |r,wU:30.32,wD:6.5,(-7.86,-4.75,;-9.2,-3.98,;-9.2,-2.44,;-7.86,-1.67,;-7.86,-.13,;-6.53,.64,;-5.19,-.13,;-4.57,-1.54,;-3.04,-1.38,;-2.72,.13,;-4.05,.9,;-4.05,2.44,;-2.72,3.21,;-1.38,2.44,;-1.38,.9,;-.05,.13,;-.05,-1.41,;1.28,-2.18,;2.62,-1.41,;2.62,.13,;1.28,.9,;1.28,2.44,;3.95,.9,;3.95,2.44,;5.29,3.21,;5.29,4.75,;6.62,2.44,;7.95,3.21,;9.29,2.44,;10.62,3.21,;11.95,2.44,;11.95,.9,;13.42,.42,;14.32,1.67,;15.86,1.67,;13.42,2.92,;6.62,.9,;7.95,.13,;7.95,-1.41,;5.29,.13,;-9.2,.64,;-10.53,-.13,;-10.53,-1.67,;-11.86,-2.44,;-13.2,-1.67,;-13.2,-.13,;-14.53,.64,;-15.86,-.13,;-15.86,-1.67,;-14.53,-2.44,;-15.06,-1.34,;-15.06,-.28,;-14.53,2.18,;-13.2,2.95,;-15.86,2.95,;-9.2,2.18,;-10.53,2.95,;-7.86,2.95,;-9.2,3.72,)|

BDBM461724

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(F)c(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC[C@H](C1)C(O)=O)C(F)(F)F |r|

BDBM461725

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC(C)(C)CC(O)=O)cc1C(F)(F)F |r|

BDBM461726

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC2(CC2)C(O)=O)cc1C(F)(F)F |r|

BDBM461727

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1C(F)(F)F |r,wU:12.12,wD:30.38,(7.95,-1.41,;7.95,.13,;6.62,.9,;5.29,.13,;3.95,.9,;3.95,2.44,;5.29,3.21,;5.29,4.75,;6.62,2.44,;7.95,3.21,;9.29,2.44,;10.62,3.21,;11.95,2.44,;11.95,.9,;13.42,.42,;14.32,1.67,;15.86,1.67,;13.42,2.92,;2.62,.13,;2.62,-1.41,;1.28,-2.18,;-.05,-1.41,;-.05,.13,;1.28,.9,;1.28,2.44,;-1.38,.9,;-1.38,2.44,;-2.72,3.21,;-4.05,2.44,;-4.05,.9,;-5.19,-.13,;-4.57,-1.54,;-3.04,-1.38,;-2.72,.13,;-6.53,.64,;-7.86,-.13,;-7.86,-1.67,;-9.2,-2.44,;-9.2,-3.98,;-7.86,-4.75,;-10.53,-1.67,;-11.86,-2.44,;-13.2,-1.67,;-13.2,-.13,;-14.53,.64,;-15.86,-.13,;-15.86,-1.67,;-14.53,-2.44,;-15.06,-1.34,;-15.06,-.28,;-14.53,2.18,;-13.2,2.95,;-15.86,2.95,;-10.53,-.13,;-9.2,.64,;-9.2,2.18,;-10.53,2.95,;-7.86,2.95,;-9.2,3.72,)|

BDBM461728

COc1cc(cc(F)c1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461729

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNC(C)(C)CC(O)=O)C(F)(F)F |r|

BDBM461730

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC(C)(C)CC(O)=O)cc1Cl |r|

BDBM461731

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@H]3C[C@]3(C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461732

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@@H]3C[C@@]3(C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461733

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC2CC2)c(CN2CC[C@H](C2)C(O)=O)cc1Cl |r|

BDBM461734

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC2CC2)c(CNC2(CC2)C(O)=O)cc1Cl |r|

BDBM461735

COc1nc(ccc1CNC[C@@H]1CC(O)C(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@](C)(C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461736

COc1nc(ccc1CNC[C@@H]1CC(O)C(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:30.38,(4.55,5.14,;5.88,4.37,;5.88,2.83,;4.55,2.06,;4.55,.52,;5.88,-.25,;7.21,.52,;7.21,2.06,;8.55,2.83,;9.88,2.06,;11.22,2.83,;12.55,2.06,;13.02,.59,;14.56,.59,;15.33,-.74,;15.04,2.06,;16.37,2.83,;13.79,2.96,;3.21,-.25,;3.21,-1.79,;1.88,-2.56,;.55,-1.79,;.55,-.25,;1.88,.52,;1.88,2.06,;-.79,.52,;-.79,2.06,;-2.12,2.83,;-3.46,2.06,;-3.46,.52,;-4.6,-.52,;-3.97,-1.92,;-2.44,-1.76,;-2.12,-.25,;-5.93,.25,;-7.27,-.52,;-7.27,-2.06,;-8.6,-2.83,;-8.6,-4.37,;-7.27,-5.14,;-9.93,-2.06,;-11.27,-2.83,;-12.6,-2.06,;-13,-.57,;-14.49,-.17,;-15.58,-1.26,;-15.18,-2.75,;-13.69,-3.14,;-14.49,-2.21,;-14.76,-1.19,;-14.89,1.32,;-16.37,1.72,;-13.8,2.41,;-9.93,-.52,;-8.6,.25,;-8.6,1.79,;-9.93,2.56,;-7.27,2.56,;-8.6,3.33,)|

BDBM461737

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CC(O)C(=O)N3)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461738

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@]3(C)C[C@@](C)(O)C3)c(OC)n2)c(cc1CNCC(O)=O)C(F)(F)F |r,wU:28.30,31.34,wD:6.5,28.31,31.35,(-6.11,-5.49,;-7.45,-4.72,;-7.45,-3.18,;-6.11,-2.41,;-6.11,-.87,;-4.78,-.1,;-3.45,-.87,;-2.82,-2.28,;-1.29,-2.12,;-.97,-.61,;-2.3,.16,;-2.3,1.7,;-.97,2.47,;.37,1.7,;.37,.16,;1.7,-.61,;1.7,-2.15,;3.03,-2.92,;4.37,-2.15,;4.37,-.61,;3.03,.16,;3.03,1.7,;5.7,.16,;7.03,-.61,;8.37,.16,;8.37,1.7,;9.7,2.47,;11.04,1.7,;12.37,2.47,;12.77,.98,;13.91,2.47,;13.91,4.01,;14.31,5.49,;15.45,4.01,;12.37,4.01,;7.03,2.47,;7.03,4.01,;5.7,4.78,;5.7,1.7,;-7.45,-.1,;-8.78,-.87,;-8.78,-2.41,;-10.11,-3.18,;-11.45,-2.41,;-12.78,-3.18,;-14.12,-2.41,;-15.45,-3.18,;-14.12,-.87,;-7.45,1.44,;-8.78,2.21,;-6.11,2.21,;-7.45,2.98,)|

BDBM461739

COc1nc(ccc1CNC[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNCC(O)=O)cc1C(F)(F)F |r,wU:11.11,13.14,wD:29.37,13.15,(4.86,5.14,;6.19,4.37,;6.19,2.83,;4.86,2.06,;4.86,.52,;6.19,-.25,;7.52,.52,;7.52,2.06,;8.86,2.83,;10.19,2.06,;11.52,2.83,;12.86,2.06,;14.19,2.83,;14.96,1.49,;16.29,2.26,;15.36,0,;13.63,.72,;3.52,-.25,;3.52,-1.79,;2.19,-2.56,;.85,-1.79,;.85,-.25,;2.19,.52,;2.19,2.06,;-.48,.52,;-.48,2.06,;-1.81,2.83,;-3.15,2.06,;-3.15,.52,;-4.29,-.52,;-3.67,-1.92,;-2.13,-1.76,;-1.81,-.25,;-5.63,.25,;-6.96,-.52,;-6.96,-2.06,;-8.29,-2.83,;-8.29,-4.37,;-6.96,-5.14,;-9.63,-2.06,;-10.96,-2.83,;-12.29,-2.06,;-13.63,-2.83,;-14.96,-2.06,;-16.29,-2.83,;-14.96,-.52,;-9.63,-.52,;-8.29,.25,;-8.29,1.79,;-9.63,2.56,;-6.96,2.56,;-8.29,3.33,)|

BDBM461740

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r,wU:29.31,31.34,wD:6.5,31.35,(-6.96,-5.14,;-8.29,-4.37,;-8.29,-2.83,;-6.96,-2.06,;-6.96,-.52,;-5.63,.25,;-4.29,-.52,;-3.67,-1.92,;-2.13,-1.76,;-1.81,-.25,;-3.15,.52,;-3.15,2.06,;-1.81,2.83,;-.48,2.06,;-.48,.52,;.85,-.25,;.85,-1.79,;2.19,-2.56,;3.52,-1.79,;3.52,-.25,;2.19,.52,;2.19,2.06,;4.86,.52,;6.19,-.25,;7.52,.52,;7.52,2.06,;8.86,2.83,;10.19,2.06,;11.52,2.83,;12.86,2.06,;14.19,2.83,;14.96,1.49,;16.29,2.26,;15.36,0,;13.63,.72,;6.19,2.83,;6.19,4.37,;4.86,5.14,;4.86,2.06,;-8.29,.25,;-9.63,-.52,;-9.63,-2.06,;-10.96,-2.83,;-12.29,-2.06,;-13.63,-2.83,;-14.4,-4.16,;-12.86,-4.16,;-14.96,-2.06,;-16.29,-2.83,;-14.96,-.52,;-8.29,1.79,;-9.63,2.56,;-6.96,2.56,;-8.29,3.33,)|

BDBM461741

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN1CC[C@](C)(C1)C(O)=O)C(F)(F)F |r,wU:29.31,31.34,46.55,wD:6.5,31.35,46.52,(-5.71,-5.4,;-7.19,-5,;-7.59,-3.52,;-6.5,-2.43,;-6.9,-.94,;-5.81,.15,;-4.33,-.25,;-3.7,-1.66,;-2.17,-1.49,;-1.85,.01,;-3.18,.78,;-3.18,2.32,;-1.85,3.09,;-.51,2.32,;-.51,.78,;.82,.01,;.82,-1.53,;2.15,-2.3,;3.49,-1.53,;3.49,.01,;2.15,.78,;2.15,2.32,;4.82,.78,;6.15,.01,;7.49,.78,;7.49,2.32,;8.82,3.09,;10.16,2.32,;11.49,3.09,;12.82,2.32,;14.31,2.72,;14.71,1.23,;16.25,1.23,;15.48,-.1,;13.22,.83,;6.15,3.09,;6.15,4.63,;4.82,5.4,;4.82,2.32,;-8.39,-.54,;-9.48,-1.63,;-9.08,-3.12,;-10.17,-4.21,;-11.66,-3.81,;-12.9,-4.71,;-14.15,-3.81,;-13.67,-2.34,;-14.07,-.86,;-12.13,-2.34,;-15.16,-1.94,;-16.25,-3.03,;-15.56,-.46,;-8.79,.95,;-7.7,2.04,;-10.28,1.35,;-9.19,2.43,)|

BDBM461742

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN1CC2(CCC1CC2)C(O)=O)C(F)(F)F |r,wU:29.31,31.34,wD:6.5,31.35,(-7.07,-5.14,;-8.41,-4.37,;-8.41,-2.83,;-7.07,-2.06,;-7.07,-.52,;-5.74,.25,;-4.41,-.52,;-3.78,-1.92,;-2.25,-1.76,;-1.93,-.25,;-3.26,.52,;-3.26,2.06,;-1.93,2.83,;-.59,2.06,;-.59,.52,;.74,-.25,;.74,-1.79,;2.07,-2.56,;3.41,-1.79,;3.41,-.25,;2.07,.52,;2.07,2.06,;4.74,.52,;6.07,-.25,;7.41,.52,;7.41,2.06,;8.74,2.83,;10.08,2.06,;11.41,2.83,;12.74,2.06,;14.08,2.83,;14.85,1.49,;16.18,2.26,;15.25,0,;13.51,.72,;6.07,2.83,;6.07,4.37,;4.74,5.14,;4.74,2.06,;-8.41,.25,;-9.74,-.52,;-9.74,-2.06,;-11.07,-2.83,;-12.41,-2.06,;-12.81,-.57,;-14.29,-.17,;-15.38,-1.26,;-14.98,-2.75,;-13.5,-3.14,;-14.29,-2.21,;-14.57,-1.19,;-14.69,1.32,;-16.18,1.72,;-13.6,2.41,;-8.41,1.79,;-9.74,2.56,;-7.07,2.56,;-8.41,3.33,)|

BDBM461743

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN(C)CC(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,(-6.37,-5.14,;-7.7,-4.37,;-7.7,-2.83,;-6.37,-2.06,;-6.37,-.52,;-5.04,.25,;-3.7,-.52,;-3.08,-1.92,;-1.54,-1.76,;-1.22,-.25,;-2.56,.52,;-2.56,2.06,;-1.22,2.83,;.11,2.06,;.11,.52,;1.44,-.25,;1.44,-1.79,;2.78,-2.56,;4.11,-1.79,;4.11,-.25,;2.78,.52,;2.78,2.06,;5.45,.52,;6.78,-.25,;8.11,.52,;8.11,2.06,;9.45,2.83,;10.78,2.06,;12.11,2.83,;12.88,4.16,;14.22,3.39,;15.31,4.48,;15.7,2.99,;13.45,2.06,;6.78,2.83,;6.78,4.37,;5.45,5.14,;5.45,2.06,;-7.7,.25,;-9.04,-.52,;-9.04,-2.06,;-10.37,-2.83,;-11.7,-2.06,;-11.7,-.52,;-13.04,-2.83,;-14.37,-2.06,;-15.7,-2.83,;-14.37,-.52,;-7.7,1.79,;-6.37,2.56,;-9.04,2.56,;-7.7,3.33,)|

BDBM461744

CC[C@H](NCc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r,wU:32.34,2.2,34.37,wD:10.9,34.38,(-13.04,-5.31,;-13.81,-3.98,;-13.04,-2.65,;-11.7,-1.88,;-10.37,-2.65,;-9.04,-1.88,;-9.04,-.34,;-7.7,.43,;-6.37,-.34,;-5.04,.43,;-3.7,-.34,;-3.08,-1.74,;-1.54,-1.58,;-1.22,-.08,;-2.56,.69,;-2.56,2.23,;-1.22,3,;.11,2.23,;.11,.69,;1.44,-.08,;1.44,-1.62,;2.78,-2.39,;4.11,-1.62,;4.11,-.08,;2.78,.69,;2.78,2.23,;5.45,.69,;6.78,-.08,;8.11,.69,;8.11,2.23,;9.45,3,;10.78,2.23,;12.11,3,;12.88,4.34,;14.22,3.57,;15.31,4.66,;15.7,3.17,;13.45,2.23,;6.78,3,;6.78,4.54,;5.45,5.31,;5.45,2.23,;-6.37,-1.88,;-7.7,-2.65,;-7.7,-4.19,;-6.37,-4.96,;-7.7,1.97,;-9.04,2.74,;-6.37,2.74,;-7.7,3.51,;-14.37,-1.88,;-15.7,-2.65,;-14.37,-.34,)|

BDBM461745

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@@H](C(C)C)C(O)=O)cc1C(F)(F)F |r,wU:10.10,41.45,12.13,wD:28.36,12.14,(5.45,5.31,;6.78,4.54,;6.78,3,;5.45,2.23,;5.45,.69,;6.78,-.08,;8.11,.69,;8.11,2.23,;9.45,3,;10.78,2.23,;12.11,3,;12.88,4.34,;14.22,3.57,;15.31,4.66,;15.7,3.17,;13.45,2.23,;4.11,-.08,;4.11,-1.62,;2.78,-2.39,;1.44,-1.62,;1.44,-.08,;2.78,.69,;2.78,2.23,;.11,.69,;.11,2.23,;-1.22,3,;-2.56,2.23,;-2.56,.69,;-3.7,-.34,;-3.08,-1.74,;-1.54,-1.58,;-1.22,-.08,;-5.04,.43,;-6.37,-.34,;-6.37,-1.88,;-7.7,-2.65,;-7.7,-4.19,;-6.37,-4.96,;-9.04,-1.88,;-10.37,-2.65,;-11.7,-1.88,;-13.04,-2.65,;-13.81,-3.98,;-13.04,-5.31,;-15.35,-3.98,;-14.37,-1.88,;-15.7,-2.65,;-14.37,-.34,;-9.04,-.34,;-7.7,.43,;-7.7,1.97,;-9.04,2.74,;-6.37,2.74,;-7.7,3.51,)|

BDBM461746

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@](C)(C2)C(O)=O)cc1C(F)(F)F |r,wU:10.10,12.13,43.51,wD:28.36,12.14,43.48,(5.49,5.35,;6.82,4.58,;6.82,3.04,;5.49,2.27,;5.49,.73,;6.82,-.04,;8.15,.73,;8.15,2.27,;9.49,3.04,;10.82,2.27,;12.16,3.04,;12.55,4.52,;14.04,4.12,;14.81,5.46,;15.58,4.12,;13.64,2.64,;4.15,-.04,;4.15,-1.58,;2.82,-2.35,;1.49,-1.58,;1.49,-.04,;2.82,.73,;2.82,2.27,;.15,.73,;.15,2.27,;-1.18,3.04,;-2.51,2.27,;-2.51,.73,;-3.66,-.31,;-3.03,-1.71,;-1.5,-1.55,;-1.18,-.04,;-5.15,.09,;-6.24,-1,;-5.84,-2.48,;-6.93,-3.57,;-6.53,-5.06,;-5.04,-5.46,;-8.41,-3.17,;-9.5,-4.26,;-10.99,-3.86,;-12.24,-4.77,;-13.48,-3.86,;-13.01,-2.4,;-13.4,-.91,;-11.47,-2.4,;-14.49,-2,;-15.58,-3.09,;-14.89,-.51,;-8.81,-1.69,;-7.72,-.6,;-8.12,.89,;-7.03,1.98,;-9.61,1.29,;-8.52,2.38,)|

BDBM461747

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNCC(O)=O)cc1C(F)(F)F |r,wU:10.10,12.13,wD:28.36,12.14,(5.45,5.14,;6.78,4.37,;6.78,2.83,;5.45,2.06,;5.45,.52,;6.78,-.25,;8.11,.52,;8.11,2.06,;9.45,2.83,;10.78,2.06,;12.11,2.83,;12.88,4.16,;14.22,3.39,;15.31,4.48,;15.7,2.99,;13.45,2.06,;4.11,-.25,;4.11,-1.79,;2.78,-2.56,;1.44,-1.79,;1.44,-.25,;2.78,.52,;2.78,2.06,;.11,.52,;.11,2.06,;-1.22,2.83,;-2.56,2.06,;-2.56,.52,;-3.7,-.52,;-3.08,-1.92,;-1.54,-1.76,;-1.22,-.25,;-5.04,.25,;-6.37,-.52,;-6.37,-2.06,;-7.7,-2.83,;-7.7,-4.37,;-6.37,-5.14,;-9.04,-2.06,;-10.37,-2.83,;-11.7,-2.06,;-13.04,-2.83,;-14.37,-2.06,;-15.7,-2.83,;-14.37,-.52,;-9.04,-.52,;-7.7,.25,;-7.7,1.79,;-9.04,2.56,;-6.37,2.56,;-7.7,3.33,)|

BDBM461748

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN[C@@H](C)C(O)=O)C(F)(F)F |r,wU:28.30,43.49,30.33,wD:6.5,30.34,(-6.37,-5.14,;-7.7,-4.37,;-7.7,-2.83,;-6.37,-2.06,;-6.37,-.52,;-5.04,.25,;-3.7,-.52,;-3.08,-1.92,;-1.54,-1.76,;-1.22,-.25,;-2.56,.52,;-2.56,2.06,;-1.22,2.83,;.11,2.06,;.11,.52,;1.44,-.25,;1.44,-1.79,;2.78,-2.56,;4.11,-1.79,;4.11,-.25,;2.78,.52,;2.78,2.06,;5.45,.52,;6.78,-.25,;8.11,.52,;8.11,2.06,;9.45,2.83,;10.78,2.06,;12.11,2.83,;12.88,4.16,;14.22,3.39,;15.31,4.48,;15.7,2.99,;13.45,2.06,;6.78,2.83,;6.78,4.37,;5.45,5.14,;5.45,2.06,;-7.7,.25,;-9.04,-.52,;-9.04,-2.06,;-10.37,-2.83,;-11.7,-2.06,;-13.04,-2.83,;-13.04,-4.37,;-14.37,-2.06,;-15.7,-2.83,;-14.37,-.52,;-7.7,1.79,;-9.04,2.56,;-6.37,2.56,;-7.7,3.33,)|

BDBM461749

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cc(F)cc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3(CCC2CC3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:30.38,(3.95,5.14,;5.29,4.37,;5.29,2.83,;3.95,2.06,;3.95,.52,;5.29,-.25,;6.62,.52,;6.62,2.06,;7.95,2.83,;9.29,2.06,;10.62,2.83,;11.95,2.06,;11.95,.52,;13.42,.04,;14.32,1.29,;15.86,1.29,;13.42,2.53,;2.62,-.25,;2.62,-1.79,;1.28,-2.56,;-.05,-1.79,;-.05,-.25,;1.28,.52,;1.28,2.06,;-1.38,.52,;-1.38,2.06,;-2.72,2.83,;-2.72,4.37,;-4.05,2.06,;-4.05,.52,;-5.19,-.52,;-4.57,-1.92,;-3.04,-1.76,;-2.72,-.25,;-6.53,.25,;-7.86,-.52,;-7.86,-2.06,;-9.2,-2.83,;-9.2,-4.37,;-7.86,-5.14,;-10.53,-2.06,;-11.86,-2.83,;-13.2,-2.06,;-13.2,-.52,;-14.53,.25,;-15.86,-.52,;-15.86,-2.06,;-14.53,-2.83,;-15.06,-1.72,;-15.06,-.66,;-14.53,1.79,;-13.2,2.56,;-15.86,2.56,;-10.53,-.52,;-9.2,.25,;-9.2,1.79,;-10.53,2.56,;-7.86,2.56,;-9.2,3.33,)|

BDBM461750

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cc(F)cc2[C@H](CCc12)Oc1nc(OC)c(CN2CC[C@H](C2)C(O)=O)cc1C(F)(F)F |r|

BDBM461751

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC[C@](C)(C1)C(O)=O)C(F)(F)F |r|

BDBM461752

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNC(C)(C)C(O)=O)C(F)(F)F |r|

BDBM461753

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461754

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNCC(C)(C)C(O)=O)C(F)(F)F |r|

BDBM461755

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNC[C@@H](O)CC(O)=O)C(F)(F)F |r|

BDBM461756

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CCC[C@@]1(C)C(O)=O)C(F)(F)F |r|

BDBM461757

COc1cc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC2CCC1C(C2)C(O)=O)C(F)(F)F |r|

BDBM461758

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cnc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNC1(CC1)C(O)=O)C(F)(F)F |r|

BDBM461759

COc1nc(ccc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3CCC2(CC3)C(O)=O)cc1C(F)(F)F |r,wD:30.39,(4.16,6.44,;5.49,5.67,;5.49,4.13,;4.16,3.36,;4.16,1.82,;5.49,1.05,;6.83,1.82,;6.83,3.36,;8.16,4.13,;9.5,3.36,;9.89,1.87,;11.38,2.27,;10.98,3.76,;11.38,.73,;12.85,.25,;13.75,1.5,;15.29,1.5,;12.85,2.74,;2.83,1.05,;2.83,-.49,;1.49,-1.26,;.16,-.49,;.16,1.05,;1.49,1.82,;1.49,3.36,;-1.17,1.82,;-1.17,3.36,;-2.51,4.13,;-3.84,3.36,;-3.84,1.82,;-4.99,.79,;-4.36,-.62,;-2.83,-.46,;-2.51,1.05,;-6.47,1.19,;-7.56,.1,;-7.16,-1.39,;-8.25,-2.48,;-7.85,-3.97,;-6.37,-4.37,;-9.74,-2.08,;-10.83,-3.17,;-12.32,-2.77,;-12.71,-1.28,;-14.2,-.89,;-15.29,-1.97,;-14.89,-3.46,;-13.41,-3.86,;-14.49,-2.77,;-13.11,-1.97,;-13.01,-5.35,;-14.1,-6.44,;-11.52,-5.75,;-10.14,-.59,;-9.05,.5,;-9.45,1.98,;-8.36,3.07,;-10.94,2.38,;-9.85,3.47,)|

BDBM461760

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN3CC4(C3)CCC(=O)N4)c(OC)n2)c(cc1CN1C2CCC1(CC2)C(O)=O)C(F)(F)F |r|

BDBM461761

COc1nc(ccc1CN1CC2(C1)CCC(=O)N2)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC3CC2(C3)C(O)=O)cc1C(F)(F)F |r,wD:30.39,(4.16,6.44,;5.49,5.67,;5.49,4.13,;4.16,3.36,;4.16,1.82,;5.49,1.05,;6.83,1.82,;6.83,3.36,;8.16,4.13,;9.5,3.36,;9.89,1.87,;11.38,2.27,;10.98,3.76,;11.38,.73,;12.85,.25,;13.75,1.5,;15.29,1.5,;12.85,2.74,;2.83,1.05,;2.83,-.49,;1.49,-1.26,;.16,-.49,;.16,1.05,;1.49,1.82,;1.49,3.36,;-1.17,1.82,;-1.17,3.36,;-2.51,4.13,;-3.84,3.36,;-3.84,1.82,;-4.99,.79,;-4.36,-.62,;-2.83,-.46,;-2.51,1.05,;-6.47,1.19,;-7.56,.1,;-7.16,-1.39,;-8.25,-2.48,;-7.85,-3.97,;-6.37,-4.37,;-9.74,-2.08,;-10.83,-3.17,;-12.32,-2.77,;-12.71,-1.28,;-14.2,-.89,;-15.29,-1.97,;-14.89,-3.46,;-13.41,-3.86,;-13.8,-2.37,;-13.01,-5.35,;-14.1,-6.44,;-11.52,-5.75,;-10.14,-.59,;-9.05,.5,;-9.45,1.98,;-8.36,3.07,;-10.94,2.38,;-9.85,3.47,)|

BDBM461762

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNC1(CCC1)C(O)=O)C(F)(F)F |r|

BDBM461763

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@@]2(C[C@H](F)C2)C(O)=O)cc1C(F)(F)F |r,wU:42.46,11.11,44.49,wD:29.37,42.52,(8.12,1.17,;8.12,2.71,;6.78,3.48,;5.45,2.71,;4.12,3.48,;4.12,5.02,;5.45,5.79,;6.78,5.02,;8.12,5.79,;9.45,5.02,;10.78,5.79,;12.12,5.02,;12.12,3.48,;13.58,3,;14.49,4.25,;16.03,4.25,;13.58,5.5,;2.78,2.71,;2.78,1.17,;1.45,.4,;.11,1.17,;.11,2.71,;1.45,3.48,;1.45,5.02,;-1.22,3.48,;-1.22,5.02,;-2.55,5.79,;-3.89,5.02,;-3.89,3.48,;-5.03,2.45,;-4.4,1.04,;-2.87,1.2,;-2.55,2.71,;-6.52,2.85,;-7.61,1.76,;-7.21,.27,;-8.3,-.82,;-7.9,-2.31,;-6.41,-2.7,;-9.79,-.42,;-10.87,-1.51,;-12.36,-1.11,;-13.45,-2.2,;-14.22,-3.53,;-12.89,-4.3,;-12.49,-5.79,;-12.12,-2.97,;-14.94,-1.8,;-16.03,-2.89,;-15.34,-.31,;-10.18,1.07,;-9.1,2.16,;-9.49,3.64,;-8.4,4.73,;-10.98,4.04,;-9.89,5.13,)|

BDBM461764

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CC3CCC2(CC3)C(O)=O)cc1Cl |r,wU:11.11,wD:29.37,(7.77,.66,;7.77,2.2,;6.44,2.97,;5.1,2.2,;3.77,2.97,;3.77,4.51,;5.1,5.28,;6.44,4.51,;7.77,5.28,;9.11,4.51,;10.44,5.28,;11.77,4.51,;11.77,2.97,;13.24,2.5,;14.14,3.74,;15.68,3.74,;13.24,4.99,;2.44,2.2,;2.44,.66,;1.1,-.11,;-.23,.66,;-.23,2.2,;1.1,2.97,;1.1,4.51,;-1.56,2.97,;-1.56,4.51,;-2.9,5.28,;-4.23,4.51,;-4.23,2.97,;-5.38,1.94,;-4.75,.53,;-3.22,.7,;-2.9,2.2,;-6.86,2.34,;-7.95,1.25,;-7.55,-.24,;-8.64,-1.32,;-8.24,-2.81,;-6.76,-3.21,;-10.13,-.93,;-11.22,-2.02,;-12.71,-1.62,;-13.11,-.13,;-14.59,.27,;-15.68,-.82,;-15.28,-2.31,;-13.8,-2.71,;-14.88,-1.62,;-13.5,-.82,;-13.4,-4.19,;-11.91,-4.59,;-14.49,-5.28,;-10.53,.56,;-9.44,1.65,;-9.84,3.14,)|

BDBM461765

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C3CCC2(CC3)C(O)=O)cc1C(F)(F)F |r|

BDBM461766

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC3CC2(C3)C(O)=O)cc1C(F)(F)F |r,wU:11.11,wD:29.37,(7.77,.66,;7.77,2.2,;6.44,2.97,;5.1,2.2,;3.77,2.97,;3.77,4.51,;5.1,5.28,;6.44,4.51,;7.77,5.28,;9.11,4.51,;10.44,5.28,;11.77,4.51,;11.77,2.97,;13.24,2.5,;14.14,3.74,;15.68,3.74,;13.24,4.99,;2.44,2.2,;2.44,.66,;1.1,-.11,;-.23,.66,;-.23,2.2,;1.1,2.97,;1.1,4.51,;-1.56,2.97,;-1.56,4.51,;-2.9,5.28,;-4.23,4.51,;-4.23,2.97,;-5.38,1.94,;-4.75,.53,;-3.22,.7,;-2.9,2.2,;-6.86,2.34,;-7.95,1.25,;-7.55,-.24,;-8.64,-1.32,;-8.24,-2.81,;-6.76,-3.21,;-10.13,-.93,;-11.22,-2.02,;-12.71,-1.62,;-13.11,-.13,;-14.59,.27,;-15.68,-.82,;-15.28,-2.31,;-13.8,-2.71,;-14.19,-1.22,;-13.4,-4.19,;-11.91,-4.59,;-14.49,-5.28,;-10.53,.56,;-9.44,1.65,;-9.84,3.14,;-8.75,4.23,;-11.33,3.54,;-10.24,4.63,)|

BDBM461767

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2C[C@H]3C[C@H]3[C@H]2C(O)=O)cc1C(F)(F)F |r|

BDBM461768

CC[C@@](C)(NCc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r|

BDBM461769

CC[C@](C)(NCc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r|

BDBM461770

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@@]2(C)C(O)=O)cc1C |r|

BDBM461771

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN2CCC[C@]2(C)C(O)=O)cc1C |r|

BDBM461772

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(C)cc1CNCC(O)=O |r|

BDBM461773

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC(C)(CO)C(O)=O)cc1C |r|

BDBM461774

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@@H](C)C(O)=O)cc1C |r|

BDBM461775

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@H](C)C(O)=O)cc1C |r|

BDBM461776

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(C)cc1CNC(C)(C)C(O)=O |r|

BDBM461777

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2cc(C)c(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(C)cc1CNC1(CC1)C(O)=O |r|

BDBM461778

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(C)cc1CNC(C)(C)C(O)=O |r|

BDBM461779

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(C)cc1CNC1(CC1)C(O)=O |r|

BDBM461780

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC2(CC2)C(O)=O)nc1C(F)(F)F |r|

BDBM461781

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNCC(=O)N(C)C)C(F)(F)F |r|

BDBM461782

CNC(=O)[C@H](C)NCc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F |r|

BDBM461783

CNC(=O)CNCc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F |r|

BDBM461784

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CNCC1(CC1)C(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,(-5.7,-5.14,;-7.04,-4.37,;-7.04,-2.83,;-5.7,-2.06,;-5.7,-.52,;-4.37,.25,;-3.03,-.52,;-2.41,-1.92,;-.88,-1.76,;-.56,-.25,;-1.89,.52,;-1.89,2.06,;-.56,2.83,;.78,2.06,;.78,.52,;2.11,-.25,;2.11,-1.79,;3.44,-2.56,;4.78,-1.79,;4.78,-.25,;3.44,.52,;3.44,2.06,;6.11,.52,;7.45,-.25,;8.78,.52,;8.78,2.06,;10.11,2.83,;11.45,2.06,;12.78,2.83,;13.55,4.16,;14.88,3.39,;15.97,4.48,;16.37,2.99,;14.11,2.06,;7.45,2.83,;7.45,4.37,;6.11,5.14,;6.11,2.06,;-7.04,.25,;-8.37,-.52,;-8.37,-2.06,;-9.7,-2.83,;-11.04,-2.06,;-12.37,-2.83,;-13.7,-2.06,;-12.93,-.72,;-14.47,-.72,;-15.04,-2.83,;-16.37,-2.06,;-15.04,-4.37,;-7.04,1.79,;-8.37,2.56,;-5.7,2.56,;-7.04,3.33,)|

BDBM461785

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CNCC(C)(C)C(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,(-5.7,-5.14,;-7.04,-4.37,;-7.04,-2.83,;-5.7,-2.06,;-5.7,-.52,;-4.37,.25,;-3.03,-.52,;-2.41,-1.92,;-.88,-1.76,;-.56,-.25,;-1.89,.52,;-1.89,2.06,;-.56,2.83,;.78,2.06,;.78,.52,;2.11,-.25,;2.11,-1.79,;3.44,-2.56,;4.78,-1.79,;4.78,-.25,;3.44,.52,;3.44,2.06,;6.11,.52,;7.45,-.25,;8.78,.52,;8.78,2.06,;10.11,2.83,;11.45,2.06,;12.78,2.83,;13.55,4.16,;14.88,3.39,;15.97,4.48,;16.37,2.99,;14.11,2.06,;7.45,2.83,;7.45,4.37,;6.11,5.14,;6.11,2.06,;-7.04,.25,;-8.37,-.52,;-8.37,-2.06,;-9.7,-2.83,;-11.04,-2.06,;-12.37,-2.83,;-13.7,-2.06,;-14.47,-.72,;-12.93,-.72,;-15.04,-2.83,;-16.37,-2.06,;-15.04,-4.37,;-7.04,1.79,;-8.37,2.56,;-5.7,2.56,;-7.04,3.33,)|

BDBM461786

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN[C@H](C)CC(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,43.49,(-5.7,-5.14,;-7.04,-4.37,;-7.04,-2.83,;-5.7,-2.06,;-5.7,-.52,;-4.37,.25,;-3.03,-.52,;-2.41,-1.92,;-.88,-1.76,;-.56,-.25,;-1.89,.52,;-1.89,2.06,;-.56,2.83,;.78,2.06,;.78,.52,;2.11,-.25,;2.11,-1.79,;3.44,-2.56,;4.78,-1.79,;4.78,-.25,;3.44,.52,;3.44,2.06,;6.11,.52,;7.45,-.25,;8.78,.52,;8.78,2.06,;10.11,2.83,;11.45,2.06,;12.78,2.83,;13.55,4.16,;14.88,3.39,;15.97,4.48,;16.37,2.99,;14.11,2.06,;7.45,2.83,;7.45,4.37,;6.11,5.14,;6.11,2.06,;-7.04,.25,;-8.37,-.52,;-8.37,-2.06,;-9.7,-2.83,;-11.04,-2.06,;-12.37,-2.83,;-12.37,-4.37,;-13.7,-2.06,;-15.04,-2.83,;-16.37,-2.06,;-15.04,-4.37,;-7.04,1.79,;-8.37,2.56,;-5.7,2.56,;-7.04,3.33,)|

BDBM461787

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CNCCC(O)=O)C(F)(F)F |r,wU:28.30,30.33,wD:6.5,30.34,(-5.7,-5.14,;-7.04,-4.37,;-7.04,-2.83,;-5.7,-2.06,;-5.7,-.52,;-4.37,.25,;-3.03,-.52,;-2.41,-1.92,;-.88,-1.76,;-.56,-.25,;-1.89,.52,;-1.89,2.06,;-.56,2.83,;.78,2.06,;.78,.52,;2.11,-.25,;2.11,-1.79,;3.44,-2.56,;4.78,-1.79,;4.78,-.25,;3.44,.52,;3.44,2.06,;6.11,.52,;7.45,-.25,;8.78,.52,;8.78,2.06,;10.11,2.83,;11.45,2.06,;12.78,2.83,;13.55,4.16,;14.88,3.39,;15.97,4.48,;16.37,2.99,;14.11,2.06,;7.45,2.83,;7.45,4.37,;6.11,5.14,;6.11,2.06,;-7.04,.25,;-8.37,-.52,;-8.37,-2.06,;-9.7,-2.83,;-11.04,-2.06,;-12.37,-2.83,;-13.7,-2.06,;-15.04,-2.83,;-16.37,-2.06,;-15.04,-4.37,;-7.04,1.79,;-8.37,2.56,;-5.7,2.56,;-7.04,3.33,)|

BDBM461788

COc1nc(ccc1CN[C@H]1C[C@](C)(O)C1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@@H](C2CC2)C(O)=O)cc1C(F)(F)F |r,wU:10.10,41.45,12.13,wD:28.36,12.14,(5.53,5.36,;6.86,4.59,;6.86,3.05,;5.53,2.28,;5.53,.74,;6.86,-.03,;8.19,.74,;8.19,2.28,;9.53,3.05,;10.86,2.28,;12.2,3.05,;12.59,4.54,;14.08,4.14,;14.85,5.47,;15.62,4.14,;13.68,2.65,;4.19,-.03,;4.19,-1.57,;2.86,-2.34,;1.53,-1.57,;1.53,-.03,;2.86,.74,;2.86,2.28,;.19,.74,;.19,2.28,;-1.14,3.05,;-2.47,2.28,;-2.47,.74,;-3.62,-.29,;-2.99,-1.7,;-1.46,-1.54,;-1.14,-.03,;-4.95,.48,;-6.29,-.29,;-6.29,-1.83,;-7.62,-2.6,;-7.62,-4.14,;-6.29,-4.91,;-8.95,-1.83,;-10.29,-2.6,;-11.62,-1.83,;-12.95,-2.6,;-12.95,-4.14,;-13.72,-5.47,;-12.18,-5.47,;-14.29,-1.83,;-15.62,-2.6,;-14.29,-.29,;-8.95,-.29,;-7.62,.48,;-7.62,2.02,;-8.95,2.79,;-6.29,2.79,;-7.62,3.56,)|

BDBM461789

COC[C@H](NCc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CN[C@H]3C[C@](C)(O)C3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r,wU:33.35,3.3,35.38,wD:11.10,35.39,(-11.62,-5.96,;-11.62,-4.42,;-12.95,-3.65,;-12.95,-2.11,;-11.62,-1.34,;-10.29,-2.11,;-8.95,-1.34,;-8.95,.2,;-7.62,.97,;-6.29,.2,;-4.95,.97,;-3.62,.2,;-2.99,-1.21,;-1.46,-1.05,;-1.14,.46,;-2.47,1.23,;-2.47,2.77,;-1.14,3.54,;.19,2.77,;.19,1.23,;1.53,.46,;1.53,-1.08,;2.86,-1.85,;4.19,-1.08,;4.19,.46,;2.86,1.23,;2.86,2.77,;5.53,1.23,;6.86,.46,;8.19,1.23,;8.19,2.77,;9.53,3.54,;10.86,2.77,;12.2,3.54,;12.59,5.03,;14.08,4.63,;14.85,5.96,;15.62,4.63,;13.68,3.14,;6.86,3.54,;6.86,5.08,;5.53,5.85,;5.53,2.77,;-6.29,-1.34,;-7.62,-2.11,;-7.62,-3.65,;-6.29,-4.42,;-7.62,2.51,;-8.95,3.28,;-6.29,3.28,;-7.62,4.05,;-14.29,-1.34,;-15.62,-2.11,;-14.29,.2,)|

BDBM461790

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN(C)[C@@H](C)C(O)=O)cc1C(F)(F)F |r|

BDBM461791

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN(C)CC(O)=O)C(F)(F)F |r|

BDBM461792

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@@H](C)C(=O)N(C)C)cc1C(F)(F)F |r|

BDBM461793

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN1CC(C)(O)C1)C(F)(F)F |r|

BDBM461794

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNC[C@H]2C[C@](C)(O)C2)cc1C(F)(F)F |r,wU:43.47,11.11,45.50,wD:29.37,45.51,(5.71,5.14,;7.04,4.37,;7.04,2.83,;5.71,2.06,;5.71,.52,;7.04,-.25,;8.37,.52,;8.37,2.06,;9.71,2.83,;11.04,2.06,;12.38,2.83,;13.71,2.06,;14.19,.59,;15.73,.59,;16.2,2.06,;17.53,2.83,;14.96,2.96,;4.37,-.25,;4.37,-1.79,;3.04,-2.56,;1.71,-1.79,;1.71,-.25,;3.04,.52,;3.04,2.06,;.37,.52,;.37,2.06,;-.96,2.83,;-2.29,2.06,;-2.29,.52,;-3.44,-.52,;-2.81,-1.92,;-1.28,-1.76,;-.96,-.25,;-4.77,.25,;-6.11,-.52,;-6.11,-2.06,;-7.44,-2.83,;-7.44,-4.37,;-6.11,-5.14,;-8.77,-2.06,;-10.11,-2.83,;-11.44,-2.06,;-12.78,-2.83,;-14.11,-2.06,;-15.6,-2.45,;-15.99,-.97,;-16.76,.37,;-17.53,-.97,;-14.51,-.57,;-8.77,-.52,;-7.44,.25,;-7.44,1.79,;-8.77,2.56,;-6.11,2.56,;-7.44,3.33,)|

BDBM461795

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNC[C@H]1C[C@H](O)C1)C(F)(F)F |r,wU:45.50,29.31,wD:6.5,47.53,(-6.21,-5.14,;-7.54,-4.37,;-7.54,-2.83,;-6.21,-2.06,;-6.21,-.52,;-4.88,.25,;-3.54,-.52,;-2.92,-1.92,;-1.38,-1.76,;-1.06,-.25,;-2.4,.52,;-2.4,2.06,;-1.06,2.83,;.27,2.06,;.27,.52,;1.6,-.25,;1.6,-1.79,;2.94,-2.56,;4.27,-1.79,;4.27,-.25,;2.94,.52,;2.94,2.06,;5.6,.52,;6.94,-.25,;8.27,.52,;8.27,2.06,;9.61,2.83,;10.94,2.06,;12.27,2.83,;13.61,2.06,;14.08,.59,;15.62,.59,;16.1,2.06,;17.43,2.83,;14.85,2.96,;6.94,2.83,;6.94,4.37,;5.6,5.14,;5.6,2.06,;-7.54,.25,;-8.88,-.52,;-8.88,-2.06,;-10.21,-2.83,;-11.54,-2.06,;-12.88,-2.83,;-14.21,-2.06,;-15.7,-2.45,;-16.1,-.97,;-17.43,-.2,;-14.61,-.57,;-7.54,1.79,;-8.88,2.56,;-6.21,2.56,;-7.54,3.33,)|

BDBM461796

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@H]2C[C@](C)(O)C2)cc1C(F)(F)F |r,wU:42.46,11.11,44.49,wD:29.37,44.50,(4.96,5.14,;6.29,4.37,;6.29,2.83,;4.96,2.06,;4.96,.52,;6.29,-.25,;7.63,.52,;7.63,2.06,;8.96,2.83,;10.3,2.06,;11.63,2.83,;12.96,2.06,;13.44,.59,;14.98,.59,;15.46,2.06,;16.79,2.83,;14.21,2.96,;3.63,-.25,;3.63,-1.79,;2.29,-2.56,;.96,-1.79,;.96,-.25,;2.29,.52,;2.29,2.06,;-.37,.52,;-.37,2.06,;-1.71,2.83,;-3.04,2.06,;-3.04,.52,;-4.19,-.52,;-3.56,-1.92,;-2.03,-1.76,;-1.71,-.25,;-5.52,.25,;-6.85,-.52,;-6.85,-2.06,;-8.19,-2.83,;-8.19,-4.37,;-6.85,-5.14,;-9.52,-2.06,;-10.85,-2.83,;-12.19,-2.06,;-13.52,-2.83,;-14.61,-3.91,;-15.7,-2.83,;-16.79,-1.74,;-16.79,-3.91,;-14.61,-1.74,;-9.52,-.52,;-8.19,.25,;-8.19,1.79,;-9.52,2.56,;-6.85,2.56,;-8.19,3.33,)|

BDBM461797

COC[C@H](NCc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r|

BDBM461798

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN[C@@H](C)C(N)=O)C(F)(F)F |r|

BDBM461799

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNCC(N)=O)C(F)(F)F |r|

BDBM461800

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CNCCC(O)=O)cc1C(F)(F)F |r|

BDBM461801

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@@H](C2CC2)C(O)=O)cc1C(F)(F)F |r|

BDBM461802

CC[C@H](NCc1cc(c(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)nc1OC)C(F)(F)F)C(O)=O |r|

BDBM461803

COc1nc(ccc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1nc(OC)c(CN[C@@H](C(C)C)C(O)=O)cc1C(F)(F)F |r|

BDBM461804

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CN[C@@H](C)C(O)=O)C(F)(F)F |r|

BDBM461805

COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@@H]3CCC(=O)N3)c(OC)n2)c(cc1CNCC(O)=O)C(F)(F)F |r|

BDBM466932

Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CCC[C@H]3C(O)=O)cc(C#N)c2o1 |r|

BDBM466976

CN1CCc2nc(sc2C1(C)C)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C |r|

BDBM467016

CC(C)N1CCc2sc(nc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(=O)NCCO)cc(C#N)c3o2)c1C |r|

BDBM467106

Cc1c(Nc2ncnc3cc(CN4CCCC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM467149

CN(CCO)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM468368

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@H](C4)C(O)=O)cnc23)c1C |r|

BDBM468369

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](C4)C(O)=O)cnc23)c1C |r|

BDBM468371

Cc1c(NC(=O)c2ccc(CNCCO)cn2)cccc1-c1cccc(NC(=O)c2ccc(CNCCO)cn2)c1Cl

BDBM468373

Cn1c2CCNCc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CNCCc3n2C)c1C#N

BDBM468374

Cn1c2CCNCc2nc1C(=O)Nc1cccc(-c2cccc(NC(=O)c3nc4CCNCc4s3)c2Cl)c1C#N

BDBM468375

Cn1c2CCNCc2nc1C(=O)Nc1cccc(-c2cccc(NC(=O)c3cn4CCNCc4n3)c2Cl)c1C#N

BDBM468376

Cn1c2CCNCc2nc1C(=O)Nc1cccc(-c2cccc(NC(=O)c3cc4CNCCn4n3)c2Cl)c1C#N

BDBM468377

Cn1c2CCNCc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CNCCc3n2C)c1Cl

BDBM468378

Cc1c(NC(=O)c2nc3CNCCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CNCCc3n2C)c1Cl

BDBM468379

CN1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CCN(C)Cc5s4)c3Cl)c1C#N)n2C

BDBM468380

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1C#N)n2C

BDBM468381

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1Cl)n2C

BDBM468382

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(C[C@H](C)O)CCc4n3C)c1Cl)n2C |r|

BDBM468383

Cc1c(NC(=O)c2nc3CN(CCO)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCO)CCc3n2C)c1Cl

BDBM468384

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1Cl)n2C |r|

BDBM468385

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1Cl)n2C |r|

BDBM468386

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1C)n2C |r|

BDBM468387

CCCC[C@@H]1N(C)C(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CN(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)CN(C)C1=O)C(C)C)C(=O)NCC(N)=O |r|

BDBM468388

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1Cl)n2C |r|

BDBM468389

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCN(CC3)S(C)(=O)=O)c1C)n2C

BDBM468390

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCOCC3)c1C)n2C

BDBM468391

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC5CCOCC5)CCc4n3C)c1C)n2C

BDBM468392

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC5(CO)CC5)CCc4n3C)c1C)n2C

BDBM468393

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H](O)CO)CCc4n3C)c1C)n2C |r|

BDBM468394

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC(O)=O)CCc4n3C)c1C)n2C

BDBM468395

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCN(CC3)C(C)=O)c1C)n2C

BDBM468396

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCC(C)(CC3)C(O)=O)c1C)n2C |(13.6,7.53,;12.83,6.19,;13.6,4.86,;12.83,3.53,;11.29,3.53,;10.52,4.86,;11.29,6.19,;9.01,4.54,;8.85,3.01,;7.52,2.24,;7.52,.7,;6.18,3.01,;4.85,2.24,;4.85,.7,;3.51,-.07,;2.18,.7,;2.18,2.24,;3.51,3.01,;3.51,4.55,;.85,3.01,;.85,4.55,;-.49,5.32,;-1.82,4.55,;-1.82,3.01,;-3.15,2.24,;-4.49,3.01,;-4.49,4.55,;-5.82,2.24,;-5.98,.71,;-7.49,.39,;-8.26,-.95,;-9.8,-.95,;-10.57,.39,;-9.8,1.72,;-8.26,1.72,;-7.23,2.86,;-7.55,4.37,;-10.57,-2.28,;-12.11,-2.28,;-12.88,-3.62,;-12.11,-4.95,;-13.6,-5.35,;-10.57,-4.95,;-9.8,-3.62,;-11.71,-6.44,;-12.8,-7.53,;-10.22,-6.84,;-.49,2.24,;-.49,.7,;10.26,2.38,;10.58,.87,)|

BDBM468397

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCCNS(C)(=O)=O)CCc4n3C)c1C)n2C

BDBM468398

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1C)n2C |r,wU:36.41,wD:33.34,(15.55,5.57,;14.78,4.24,;15.55,2.9,;14.78,1.57,;13.24,1.57,;12.47,2.9,;13.24,4.24,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;5.47,1.05,;5.47,2.59,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-2.9,;-12.47,-2.9,;-13.24,-4.24,;-12.47,-5.57,;-10.93,-5.57,;-14.78,-4.24,;-15.55,-2.9,;-15.55,-5.57,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;1.46,.28,;1.46,-1.26,;12.21,.43,;12.53,-1.08,)|

BDBM468399

CN1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CN(CCO)CCc5n4C)c3Cl)c1C#N)n2C

BDBM468400

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1C#N)n2C |r|

BDBM468401

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1C#N)n2C |r|

BDBM468402

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CNCCc4n3C)c1Cl)n2C |r|

BDBM468403

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCO)CCc4n3C)c1Cl)n2C |r|

BDBM468404

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCN(CC3)S(C)(=O)=O)c1Cl)n2C |r|

BDBM468405

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCC3)c1Cl)n2C |r|

BDBM468406

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C(C)C)c1Cl)n2C |r|

BDBM468407

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CC5CC5)CCc4n3C)c1Cl)n2C |r|

BDBM468408

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCOCC3)c1Cl)n2C |r|

BDBM468409

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3cc(CN4CC[C@@H](O)C4)cn(C)c3=O)c1C)n2C |r|

BDBM468410

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3cc(CN4CC[C@H](C4)C(O)=O)cn(C)c3=O)c1C)n2C |r|

BDBM468411

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3cc(CN4CCCC4)cn(C)c3=O)c1C)n2C

BDBM468412

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3cc(CN4CC[C@@H](O)C4)cn(C)c3=O)c1C)n2C |r|

BDBM468413

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3cc(CN4CCCC4)cn(C)c3=O)c1C)n2C |r|

BDBM468414

CN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(C)CCc3n2C)c1Cl

BDBM468415

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(COc3cc(OCc4cncc(c4)C#N)c(CN4CCCC[C@H]4C(O)=O)cc3Cl)c1C)n2C |r|

BDBM468416

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.41,wD:33.34,(15.55,5.57,;14.78,4.24,;15.55,2.9,;14.78,1.57,;13.24,1.57,;12.47,2.9,;13.24,4.24,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;5.47,1.05,;5.47,2.59,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-2.9,;-12.47,-2.9,;-13.24,-4.24,;-12.47,-5.57,;-10.93,-5.57,;-14.78,-4.24,;-15.55,-2.9,;-15.55,-5.57,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;1.46,.28,;1.46,-1.26,;12.21,.43,;12.53,-1.08,)|

BDBM468417

Cn1c2CCNCc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:37.43,wD:34.36,(12.53,-1.08,;12.21,.43,;13.24,1.57,;14.78,1.57,;15.55,2.9,;14.78,4.24,;13.24,4.24,;12.47,2.9,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;5.47,1.05,;5.47,2.59,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-2.9,;-12.47,-2.9,;-13.24,-4.24,;-12.47,-5.57,;-10.93,-5.57,;-14.78,-4.24,;-15.55,-2.9,;-15.55,-5.57,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;1.46,.28,;1.46,-1.26,)|

BDBM468418

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:37.42,wD:34.35,(16.32,5.57,;14.78,5.57,;14.01,4.24,;14.78,2.9,;14.01,1.57,;12.47,1.57,;11.7,2.9,;12.47,4.24,;10.19,2.58,;10.03,1.05,;8.7,.28,;8.7,-1.26,;7.36,1.05,;6.03,.28,;6.03,-1.26,;4.7,-2.03,;3.36,-1.26,;3.36,.28,;4.7,1.05,;4.7,2.59,;2.03,1.05,;2.03,2.59,;.69,3.36,;-.64,2.59,;-.64,1.05,;-1.97,.28,;-3.31,1.05,;-3.31,2.59,;-4.64,.28,;-4.8,-1.25,;-6.31,-1.57,;-7.08,-2.9,;-8.62,-2.9,;-9.39,-4.24,;-10.93,-4.24,;-11.7,-2.9,;-13.24,-2.9,;-14.01,-4.24,;-13.24,-5.57,;-11.7,-5.57,;-15.55,-4.24,;-16.32,-2.9,;-16.32,-5.57,;-9.39,-1.57,;-8.62,-.24,;-7.08,-.24,;-6.05,.91,;-6.37,2.41,;.69,.28,;.69,-1.26,;11.44,.43,;11.76,-1.08,)|

BDBM468419

Cn1c2CCN(CC3CC3)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:41.48,wD:38.41,(11.17,-1.45,;10.77,.04,;11.8,1.18,;13.34,1.18,;14.11,2.52,;13.34,3.85,;14.11,5.19,;15.65,5.19,;16.98,4.42,;16.98,5.96,;11.8,3.85,;11.03,2.52,;9.52,2.2,;9.36,.67,;8.03,-.1,;8.03,-1.64,;6.7,.67,;5.36,-.1,;5.36,-1.64,;4.03,-2.41,;2.7,-1.64,;2.7,-.1,;4.03,.67,;4.03,2.21,;1.36,.67,;1.36,2.21,;.03,2.98,;-1.31,2.21,;-1.31,.67,;-2.64,-.1,;-3.97,.67,;-3.97,2.21,;-5.31,-.1,;-5.47,-1.63,;-6.97,-1.95,;-7.74,-3.29,;-9.28,-3.29,;-10.05,-4.62,;-11.59,-4.62,;-12.36,-3.29,;-13.9,-3.29,;-14.67,-4.62,;-13.9,-5.96,;-12.36,-5.96,;-16.21,-4.62,;-16.98,-3.29,;-16.98,-5.96,;-10.05,-1.95,;-9.28,-.62,;-7.74,-.62,;-6.71,.52,;-7.11,2.01,;.03,-.1,;.03,-1.64,)|

BDBM468420

Cn1c2CCN(C[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl |r,wU:10.13,wD:7.6,(-6.83,1.06,;-6.43,-.43,;-7.46,-1.57,;-9,-1.57,;-9.77,-2.9,;-9,-4.24,;-9.77,-5.57,;-11.31,-5.57,;-12.08,-4.24,;-13.62,-4.24,;-14.39,-5.57,;-13.62,-6.9,;-12.08,-6.9,;-15.93,-5.57,;-16.7,-4.24,;-16.7,-6.9,;-7.46,-4.24,;-6.69,-2.9,;-5.19,-2.58,;-5.03,-1.05,;-3.69,-.28,;-3.69,1.26,;-2.36,-1.05,;-1.02,-.28,;-1.02,1.26,;.31,2.03,;1.64,1.26,;1.64,-.28,;.31,-1.05,;.31,-2.59,;2.98,-1.05,;2.98,-2.59,;4.31,-3.36,;5.64,-2.59,;5.64,-1.05,;6.98,-.28,;8.31,-1.05,;8.31,-2.59,;9.65,-.28,;9.81,1.25,;11.31,1.57,;12.08,2.9,;13.62,2.9,;14.39,1.57,;13.62,.24,;12.08,.24,;11.05,-.91,;11.45,-2.4,;14.39,4.24,;15.93,4.24,;16.7,5.57,;15.93,6.9,;14.39,6.9,;13.62,5.57,;4.31,-.28,;4.31,1.26,)|

BDBM468421

Cn1c2CCN(CCO)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:40.46,wD:37.39,(11.37,-1.75,;11.05,-.24,;12.08,.9,;13.62,.9,;14.39,2.24,;13.62,3.57,;14.39,4.9,;15.93,4.9,;16.7,6.24,;12.08,3.57,;11.31,2.24,;9.81,1.92,;9.65,.38,;8.31,-.38,;8.31,-1.93,;6.98,.38,;5.64,-.38,;5.64,-1.93,;4.31,-2.69,;2.98,-1.93,;2.98,-.38,;4.31,.38,;4.31,1.93,;1.64,.38,;1.64,1.93,;.31,2.69,;-1.02,1.93,;-1.02,.38,;-2.36,-.38,;-3.69,.38,;-3.69,1.93,;-5.03,-.38,;-5.19,-1.92,;-6.69,-2.24,;-7.46,-3.57,;-9,-3.57,;-9.77,-4.9,;-11.31,-4.9,;-12.08,-3.57,;-13.62,-3.57,;-14.39,-4.9,;-13.62,-6.24,;-12.08,-6.24,;-15.93,-4.9,;-16.7,-3.57,;-16.7,-6.24,;-9.77,-2.24,;-9,-.9,;-7.46,-.9,;-6.43,.24,;-6.75,1.75,;.31,-.38,;.31,-1.93,)|

BDBM468422

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:39.44,wD:36.37,1.1,(16.7,6.24,;15.93,4.9,;16.7,3.57,;14.39,4.9,;13.62,3.57,;14.39,2.24,;13.62,.9,;12.08,.9,;11.31,2.24,;12.08,3.57,;9.81,1.92,;9.65,.39,;8.31,-.39,;8.31,-1.93,;6.98,.39,;5.64,-.39,;5.64,-1.93,;4.31,-2.7,;2.98,-1.93,;2.98,-.39,;4.31,.39,;4.31,1.93,;1.64,.39,;1.64,1.93,;.31,2.7,;-1.02,1.93,;-1.02,.39,;-2.36,-.39,;-3.69,.39,;-3.69,1.93,;-5.03,-.39,;-5.19,-1.92,;-6.69,-2.24,;-7.46,-3.57,;-9,-3.57,;-9.77,-4.9,;-11.31,-4.9,;-12.08,-3.57,;-13.62,-3.57,;-14.39,-4.9,;-13.62,-6.24,;-12.08,-6.24,;-15.93,-4.9,;-16.7,-3.57,;-16.7,-6.24,;-9.77,-2.24,;-9,-.9,;-7.46,-.9,;-6.43,.24,;-6.83,1.73,;.31,-.39,;.31,-1.93,;11.05,-.24,;11.45,-1.73,)|

BDBM468423

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:39.44,1.1,wD:36.37,(16.7,6.24,;15.93,4.9,;16.7,3.57,;14.39,4.9,;13.62,3.57,;14.39,2.24,;13.62,.9,;12.08,.9,;11.31,2.24,;12.08,3.57,;9.81,1.92,;9.65,.39,;8.31,-.39,;8.31,-1.93,;6.98,.39,;5.64,-.39,;5.64,-1.93,;4.31,-2.7,;2.98,-1.93,;2.98,-.39,;4.31,.39,;4.31,1.93,;1.64,.39,;1.64,1.93,;.31,2.7,;-1.02,1.93,;-1.02,.39,;-2.36,-.39,;-3.69,.39,;-3.69,1.93,;-5.03,-.39,;-5.19,-1.92,;-6.69,-2.24,;-7.46,-3.57,;-9,-3.57,;-9.77,-4.9,;-11.31,-4.9,;-12.08,-3.57,;-13.62,-3.57,;-14.39,-4.9,;-13.62,-6.24,;-12.08,-6.24,;-15.93,-4.9,;-16.7,-3.57,;-16.7,-6.24,;-9.77,-2.24,;-9,-.9,;-7.46,-.9,;-6.43,.24,;-6.83,1.73,;.31,-.39,;.31,-1.93,;11.05,-.24,;11.45,-1.73,)|

BDBM468424

Cn1c2CCNCc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:34.36,37.43,(12.53,-1.08,;12.21,.43,;13.24,1.57,;14.78,1.57,;15.55,2.9,;14.78,4.24,;13.24,4.24,;12.47,2.9,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;5.47,1.05,;5.47,2.59,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-5.57,;-12.47,-5.57,;-13.24,-4.24,;-12.47,-2.9,;-10.93,-2.9,;-14.78,-4.24,;-15.55,-5.57,;-15.55,-2.9,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;1.46,.28,;1.46,-1.26,)|

BDBM468425

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:33.34,36.41,(15.55,5.57,;14.78,4.24,;15.55,2.9,;14.78,1.57,;13.24,1.57,;12.47,2.9,;13.24,4.24,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;5.47,1.05,;5.47,2.59,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-5.57,;-12.47,-5.57,;-13.24,-4.24,;-12.47,-2.9,;-10.93,-2.9,;-14.78,-4.24,;-15.55,-2.9,;-15.55,-5.57,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;1.46,.28,;1.46,-1.26,;12.21,.43,;12.53,-1.08,)|

BDBM468426

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:34.35,37.42,(16.32,5.57,;14.78,5.57,;14.01,4.24,;14.78,2.9,;14.01,1.57,;12.47,1.57,;11.7,2.9,;12.47,4.24,;10.19,2.58,;10.03,1.05,;8.7,.28,;8.7,-1.26,;7.36,1.05,;6.03,.28,;6.03,-1.26,;4.7,-2.03,;3.36,-1.26,;3.36,.28,;4.7,1.05,;4.7,2.59,;2.03,1.05,;2.03,2.59,;.69,3.36,;-.64,2.59,;-.64,1.05,;-1.97,.28,;-3.31,1.05,;-3.31,2.59,;-4.64,.28,;-4.8,-1.25,;-6.31,-1.57,;-7.08,-2.9,;-8.62,-2.9,;-9.39,-4.24,;-10.93,-4.24,;-11.7,-5.57,;-13.24,-5.57,;-14.01,-4.24,;-13.24,-2.9,;-11.7,-2.9,;-15.55,-4.24,;-16.32,-2.9,;-16.32,-5.57,;-9.39,-1.57,;-8.62,-.24,;-7.08,-.24,;-6.05,.91,;-6.45,2.4,;.69,.28,;.69,-1.26,;11.44,.43,;11.84,-1.06,)|

BDBM468427

Cn1c2CCN(CC3CC3)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:38.41,41.48,(11.17,-1.45,;10.77,.04,;11.8,1.18,;13.34,1.18,;14.11,2.52,;13.34,3.85,;14.11,5.19,;15.65,5.19,;16.98,4.42,;16.98,5.96,;11.8,3.85,;11.03,2.52,;9.52,2.2,;9.36,.67,;8.03,-.1,;8.03,-1.64,;6.7,.67,;5.36,-.1,;5.36,-1.64,;4.03,-2.41,;2.69,-1.64,;2.69,-.1,;4.03,.67,;4.03,2.21,;1.36,.67,;1.36,2.21,;.03,2.98,;-1.31,2.21,;-1.31,.67,;-2.64,-.1,;-3.97,.67,;-3.97,2.21,;-5.31,-.1,;-5.47,-1.63,;-6.97,-1.95,;-7.74,-3.29,;-9.28,-3.29,;-10.05,-4.62,;-11.59,-4.62,;-12.36,-5.96,;-13.9,-5.96,;-14.67,-4.62,;-13.9,-3.29,;-12.36,-3.29,;-16.21,-4.62,;-16.98,-3.29,;-16.98,-5.96,;-10.05,-1.95,;-9.28,-.62,;-7.74,-.62,;-6.71,.52,;-7.11,2.01,;.03,-.1,;.03,-1.64,)|

BDBM468428

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:35.36,38.43,(16.32,4.9,;14.78,4.9,;14.01,6.24,;14.01,3.57,;14.78,2.24,;14.01,.9,;12.47,.9,;11.7,2.24,;12.47,3.57,;10.19,1.92,;10.03,.39,;8.7,-.39,;8.7,-1.92,;7.36,.39,;6.03,-.39,;6.03,-1.92,;4.7,-2.7,;3.36,-1.92,;3.36,-.39,;4.7,.39,;4.7,1.92,;2.03,.39,;2.03,1.92,;.69,2.7,;-.64,1.92,;-.64,.39,;-1.97,-.39,;-3.31,.39,;-3.31,1.92,;-4.64,-.39,;-4.8,-1.92,;-6.31,-2.24,;-7.08,-3.57,;-8.62,-3.57,;-9.39,-4.9,;-10.93,-4.9,;-11.7,-6.24,;-13.24,-6.24,;-14.01,-4.9,;-13.24,-3.57,;-11.7,-3.57,;-15.55,-4.9,;-16.32,-3.57,;-16.32,-6.24,;-9.39,-2.24,;-8.62,-.9,;-7.08,-.9,;-6.05,.24,;-6.45,1.73,;.69,-.39,;.69,-1.92,;11.44,-.24,;11.84,-1.73,)|

BDBM468429

Cn1c2CCN(C[C@H]3CC[C@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl |r,wU:7.6,10.13,(-6.83,1.06,;-6.43,-.43,;-7.46,-1.57,;-9,-1.57,;-9.77,-2.9,;-9,-4.24,;-9.77,-5.57,;-11.31,-5.57,;-12.08,-6.9,;-13.62,-6.9,;-14.39,-5.57,;-13.62,-4.24,;-12.08,-4.24,;-15.93,-5.57,;-16.7,-4.24,;-16.7,-6.9,;-7.46,-4.24,;-6.69,-2.9,;-5.19,-2.58,;-5.03,-1.05,;-3.69,-.28,;-3.69,1.26,;-2.36,-1.05,;-1.02,-.28,;-1.02,1.26,;.31,2.03,;1.64,1.26,;1.64,-.28,;.31,-1.05,;.31,-2.59,;2.98,-1.05,;2.98,-2.59,;4.31,-3.36,;5.64,-2.59,;5.64,-1.05,;6.98,-.28,;8.31,-1.05,;8.31,-2.59,;9.64,-.28,;9.81,1.25,;11.31,1.57,;12.08,2.9,;13.62,2.9,;14.39,1.57,;13.62,.24,;12.08,.24,;11.05,-.91,;11.45,-2.4,;14.39,4.24,;15.93,4.24,;16.7,5.57,;15.93,6.9,;14.39,6.9,;13.62,5.57,;4.31,-.28,;4.31,1.26,)|

BDBM468430

Cn1c2CCN(CCO)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:37.39,40.46,(11.37,-1.75,;11.05,-.24,;12.08,.9,;13.62,.9,;14.39,2.24,;13.62,3.57,;14.39,4.9,;15.93,4.9,;16.7,6.24,;12.08,3.57,;11.31,2.24,;9.81,1.92,;9.65,.38,;8.31,-.39,;8.31,-1.93,;6.98,.38,;5.64,-.39,;5.64,-1.93,;4.31,-2.7,;2.98,-1.93,;2.98,-.39,;4.31,.38,;4.31,1.92,;1.64,.38,;1.64,1.92,;.31,2.69,;-1.02,1.92,;-1.02,.38,;-2.36,-.39,;-3.69,.38,;-3.69,1.92,;-5.03,-.39,;-5.19,-1.92,;-6.69,-2.24,;-7.46,-3.57,;-9,-3.57,;-9.77,-4.9,;-11.31,-4.9,;-12.08,-6.24,;-13.62,-6.24,;-14.39,-4.9,;-13.62,-3.57,;-12.08,-3.57,;-15.93,-4.9,;-16.7,-3.57,;-16.7,-6.24,;-9.77,-2.24,;-9,-.9,;-7.46,-.9,;-6.43,.24,;-6.75,1.75,;.31,-.39,;.31,-1.93,)|

BDBM468431

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.37,39.44,wD:1.1,(16.7,6.24,;15.93,4.9,;16.7,3.57,;14.39,4.9,;13.62,3.57,;14.39,2.24,;13.62,.9,;12.08,.9,;11.31,2.24,;12.08,3.57,;9.81,1.92,;9.65,.39,;8.31,-.39,;8.31,-1.92,;6.98,.39,;5.64,-.39,;5.64,-1.92,;4.31,-2.69,;2.98,-1.92,;2.98,-.39,;4.31,.39,;4.31,1.92,;1.64,.39,;1.64,1.92,;.31,2.69,;-1.02,1.92,;-1.02,.39,;-2.36,-.39,;-3.69,.39,;-3.69,1.92,;-5.03,-.39,;-5.19,-1.92,;-6.69,-2.24,;-7.46,-3.57,;-9,-3.57,;-9.77,-4.9,;-11.31,-4.9,;-12.08,-6.24,;-13.62,-6.24,;-14.39,-4.9,;-13.62,-3.57,;-12.08,-3.57,;-15.93,-4.9,;-16.7,-3.57,;-16.7,-6.24,;-9.77,-2.24,;-9,-.9,;-7.46,-.9,;-6.43,.24,;-6.83,1.73,;.31,-.39,;.31,-1.92,;11.05,-.24,;11.45,-1.73,)|

BDBM468432

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.37,39.44,1.1,(16.7,6.24,;15.93,4.9,;16.7,3.57,;14.39,4.9,;13.62,3.57,;14.39,2.24,;13.62,.9,;12.08,.9,;11.31,2.24,;12.08,3.57,;9.81,1.92,;9.65,.39,;8.31,-.39,;8.31,-1.92,;6.98,.39,;5.64,-.39,;5.64,-1.92,;4.31,-2.69,;2.98,-1.92,;2.98,-.39,;4.31,.39,;4.31,1.92,;1.64,.39,;1.64,1.92,;.31,2.69,;-1.02,1.92,;-1.02,.39,;-2.36,-.39,;-3.69,.39,;-3.69,1.92,;-5.03,-.39,;-5.19,-1.92,;-6.69,-2.24,;-7.46,-3.57,;-9,-3.57,;-9.77,-4.9,;-11.31,-4.9,;-12.08,-6.24,;-13.62,-6.24,;-14.39,-4.9,;-13.62,-3.57,;-12.08,-3.57,;-15.93,-4.9,;-16.7,-3.57,;-16.7,-6.24,;-9.77,-2.24,;-9,-.9,;-7.46,-.9,;-6.43,.24,;-6.83,1.73,;.31,-.39,;.31,-1.92,;11.05,-.24,;11.45,-1.73,)|

BDBM468433

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:34.35,37.42,(15.16,8.24,;14.39,6.9,;15.16,5.57,;14.39,4.24,;12.85,4.24,;12.08,5.57,;12.85,6.9,;10.58,5.25,;10.42,3.72,;9.08,2.95,;9.08,1.41,;7.75,3.72,;6.41,2.95,;6.41,1.41,;5.08,.64,;3.75,1.41,;3.75,2.95,;5.08,3.72,;5.08,5.26,;2.41,3.72,;2.41,5.26,;1.08,6.03,;-.25,5.26,;-.25,3.72,;-1.59,2.95,;-2.92,3.72,;-2.92,5.26,;-4.26,2.95,;-4.42,1.42,;-5.92,1.1,;-6.69,-.24,;-8.23,-.24,;-9,-1.57,;-10.54,-1.57,;-11.31,-2.9,;-10.54,-4.24,;-11.31,-5.57,;-12.85,-5.57,;-13.62,-4.24,;-12.85,-2.9,;-13.62,-6.9,;-15.16,-6.9,;-12.85,-8.24,;-9,1.1,;-8.23,2.43,;-6.69,2.43,;-5.66,3.58,;-5.98,5.08,;1.08,2.95,;1.08,1.41,;11.82,3.09,;12.14,1.59,)|

BDBM468434

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:34.35,wD:37.42,(15.16,8.24,;14.39,6.9,;15.16,5.57,;14.39,4.24,;12.85,4.24,;12.08,5.57,;12.85,6.9,;10.58,5.25,;10.42,3.72,;9.08,2.95,;9.08,1.41,;7.75,3.72,;6.41,2.95,;6.41,1.41,;5.08,.64,;3.75,1.41,;3.75,2.95,;5.08,3.72,;5.08,5.26,;2.41,3.72,;2.41,5.26,;1.08,6.03,;-.25,5.26,;-.25,3.72,;-1.59,2.95,;-2.92,3.72,;-2.92,5.26,;-4.26,2.95,;-4.42,1.42,;-5.92,1.1,;-6.69,-.24,;-8.23,-.24,;-9,-1.57,;-10.54,-1.57,;-11.31,-2.9,;-10.54,-4.24,;-11.31,-5.57,;-12.85,-5.57,;-13.62,-4.24,;-12.85,-2.9,;-13.62,-6.9,;-15.16,-6.9,;-12.85,-8.24,;-9,1.1,;-8.23,2.43,;-6.69,2.43,;-5.66,3.58,;-5.98,5.08,;1.08,2.95,;1.08,1.41,;11.82,3.09,;12.14,1.59,)|

BDBM468435

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc5ccc(cc5)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM468436

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCC(CC3)C(O)=O)c1Cl)n2C |(14.01,7.57,;13.24,6.24,;14.01,4.9,;13.24,3.57,;11.7,3.57,;10.93,4.9,;11.7,6.24,;9.42,4.58,;9.26,3.05,;7.93,2.28,;7.93,.74,;6.59,3.05,;5.26,2.28,;5.26,.74,;3.93,-.03,;2.59,.74,;2.59,2.28,;3.93,3.05,;3.93,4.59,;1.26,3.05,;1.26,4.59,;-.08,5.36,;-1.41,4.59,;-1.41,3.05,;-2.74,2.28,;-4.08,3.05,;-4.08,4.59,;-5.41,2.28,;-5.57,.75,;-7.08,.43,;-7.85,-.9,;-9.39,-.9,;-10.16,.43,;-9.39,1.76,;-7.85,1.76,;-6.82,2.91,;-7.22,4.4,;-10.16,-2.24,;-11.7,-2.24,;-12.47,-3.57,;-11.7,-4.9,;-10.16,-4.9,;-9.39,-3.57,;-12.47,-6.24,;-14.01,-6.24,;-11.7,-7.57,;-.08,2.28,;-.08,.74,;10.67,2.43,;11.07,.94,)|

BDBM468437

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCC(C)(CC3)C(O)=O)c1Cl)n2C |(13.6,7.53,;12.83,6.19,;13.6,4.86,;12.83,3.52,;11.29,3.52,;10.52,4.86,;11.29,6.19,;9.01,4.54,;8.85,3.01,;7.52,2.24,;7.52,.7,;6.18,3.01,;4.85,2.24,;4.85,.7,;3.51,-.07,;2.18,.7,;2.18,2.24,;3.51,3.01,;3.51,4.55,;.85,3.01,;.85,4.55,;-.49,5.32,;-1.82,4.55,;-1.82,3.01,;-3.15,2.24,;-4.49,3.01,;-4.49,4.55,;-5.82,2.24,;-5.98,.71,;-7.49,.39,;-8.26,-.95,;-9.8,-.95,;-10.57,.39,;-9.8,1.72,;-8.26,1.72,;-7.23,2.86,;-7.63,4.35,;-10.57,-2.28,;-12.11,-2.28,;-12.88,-3.62,;-12.11,-4.95,;-13.6,-5.35,;-10.57,-4.95,;-9.8,-3.62,;-11.71,-6.44,;-12.8,-7.53,;-10.22,-6.84,;-.49,2.24,;-.49,.7,;10.26,2.38,;10.65,.89,)|

BDBM468438

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(CC6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM468439

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC5CC[C@](C)(CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.42,wD:36.38,(15.68,6.19,;14.91,4.86,;15.68,3.52,;14.91,2.19,;13.37,2.19,;12.6,3.52,;13.37,4.86,;11.09,3.2,;10.93,1.67,;9.6,.9,;9.6,-.64,;8.27,1.67,;6.93,.9,;6.93,-.64,;5.6,-1.41,;4.26,-.64,;4.26,.9,;5.6,1.67,;5.6,3.21,;2.93,1.67,;2.93,3.21,;1.6,3.98,;.26,3.21,;.26,1.67,;-1.07,.9,;-2.4,1.67,;-2.4,3.21,;-3.74,.9,;-3.9,-.63,;-5.4,-.95,;-6.17,-2.28,;-7.71,-2.28,;-8.48,-3.62,;-10.02,-3.62,;-10.79,-4.95,;-12.33,-4.95,;-13.1,-3.62,;-14.44,-2.85,;-12.33,-2.28,;-10.79,-2.28,;-14.19,-4.7,;-15.68,-4.31,;-13.79,-6.19,;-8.48,-.95,;-7.71,.39,;-6.17,.39,;-5.14,1.53,;-5.54,3.02,;1.6,.9,;1.6,-.64,;12.34,1.05,;12.74,-.44,)|

BDBM468440

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC5CC[C@](C)(CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.38,wD:36.42,(15.68,6.19,;14.91,4.86,;15.68,3.52,;14.91,2.19,;13.37,2.19,;12.6,3.52,;13.37,4.86,;11.09,3.2,;10.93,1.67,;9.6,.9,;9.6,-.64,;8.27,1.67,;6.93,.9,;6.93,-.64,;5.6,-1.41,;4.26,-.64,;4.26,.9,;5.6,1.67,;5.6,3.21,;2.93,1.67,;2.93,3.21,;1.6,3.98,;.26,3.21,;.26,1.67,;-1.07,.9,;-2.4,1.67,;-2.4,3.21,;-3.74,.9,;-3.9,-.63,;-5.4,-.95,;-6.17,-2.28,;-7.71,-2.28,;-8.48,-3.62,;-10.02,-3.62,;-10.79,-2.28,;-12.33,-2.28,;-13.1,-3.62,;-14.44,-2.85,;-12.33,-4.95,;-10.79,-4.95,;-14.19,-4.7,;-15.68,-4.31,;-13.79,-6.19,;-8.48,-.95,;-7.71,.39,;-6.17,.39,;-5.14,1.53,;-5.54,3.02,;1.6,.9,;1.6,-.64,;12.34,1.05,;12.74,-.44,)|

BDBM468441

CCC1(CCC(CC1)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1Cl)n2C)C(O)=O |(-14.14,-4.26,;-13.05,-5.35,;-11.56,-4.95,;-12.33,-3.62,;-11.56,-2.28,;-10.02,-2.28,;-9.25,-3.62,;-10.02,-4.95,;-9.25,-.95,;-10.02,.39,;-9.25,1.72,;-7.71,1.72,;-6.94,.39,;-7.71,-.95,;-5.44,.71,;-5.28,2.24,;-3.94,3.01,;-3.94,4.55,;-2.61,2.24,;-1.28,3.01,;-1.28,4.55,;.06,5.32,;1.39,4.55,;1.39,3.01,;.06,2.24,;.06,.7,;2.73,2.24,;2.73,.7,;4.06,-.07,;5.39,.7,;5.39,2.24,;6.73,3.01,;8.06,2.24,;8.06,.7,;9.39,3.01,;9.55,4.54,;11.06,4.86,;11.83,6.19,;13.37,6.19,;14.14,7.53,;14.14,4.86,;13.37,3.53,;11.83,3.53,;10.8,2.38,;11.12,.87,;4.06,3.01,;4.06,4.55,;-6.68,2.86,;-7,4.37,;-11.17,-6.44,;-12.25,-7.53,;-9.68,-6.84,)|

BDBM468442

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM468443

Cn1c2CCNCc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:38.44,wD:35.37,(12.14,1.59,;11.82,3.09,;12.85,4.24,;14.39,4.24,;15.16,5.57,;14.39,6.9,;12.85,6.9,;12.08,5.57,;10.58,5.25,;10.42,3.72,;9.08,2.95,;9.08,1.41,;7.75,3.72,;6.41,2.95,;6.41,1.41,;5.08,.64,;3.75,1.41,;3.75,2.95,;5.08,3.72,;5.08,5.26,;2.41,3.72,;2.41,5.26,;1.08,6.03,;-.25,5.26,;-.25,3.72,;-1.59,2.95,;-2.92,3.72,;-2.92,5.26,;-4.26,2.95,;-4.42,1.42,;-5.92,1.1,;-6.69,-.24,;-8.23,-.24,;-9,-1.57,;-10.54,-1.57,;-11.31,-2.9,;-12.85,-2.9,;-13.62,-4.24,;-12.85,-5.57,;-11.31,-5.57,;-10.54,-4.24,;-13.62,-6.9,;-15.16,-6.9,;-12.85,-8.24,;-9,1.1,;-8.23,2.43,;-6.69,2.43,;-5.66,3.58,;-5.98,5.08,;1.08,2.95,;1.08,1.41,)|

BDBM468444

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:38.43,wD:35.36,(15.93,8.24,;14.39,8.24,;13.62,6.9,;14.39,5.57,;13.62,4.24,;12.08,4.24,;11.31,5.57,;12.08,6.9,;9.81,5.25,;9.65,3.72,;8.31,2.95,;8.31,1.41,;6.98,3.72,;5.64,2.95,;5.64,1.41,;4.31,.64,;2.98,1.41,;2.98,2.95,;4.31,3.72,;4.31,5.26,;1.64,3.72,;1.64,5.26,;.31,6.03,;-1.02,5.26,;-1.02,3.72,;-2.36,2.95,;-3.69,3.72,;-3.69,5.26,;-5.03,2.95,;-5.19,1.42,;-6.69,1.1,;-7.46,-.24,;-9,-.24,;-9.77,-1.57,;-11.31,-1.57,;-12.08,-2.9,;-13.62,-2.9,;-14.39,-4.24,;-13.62,-5.57,;-12.08,-5.57,;-11.31,-4.24,;-14.39,-6.9,;-15.93,-6.9,;-13.62,-8.24,;-9.77,1.1,;-9,2.43,;-7.46,2.43,;-6.43,3.58,;-6.75,5.08,;.31,2.95,;.31,1.41,;11.05,3.09,;11.37,1.59,)|

BDBM468445

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC4CC4)CCc3n2C)c1Cl |r,wU:11.14,wD:8.7,(-7.5,4.68,;-7.1,3.19,;-8.13,2.05,;-9.67,2.05,;-10.44,.71,;-9.67,-.62,;-10.44,-1.95,;-11.98,-1.95,;-12.75,-3.29,;-14.29,-3.29,;-15.06,-4.62,;-14.29,-5.96,;-12.75,-5.96,;-11.98,-4.62,;-15.06,-7.29,;-16.6,-7.29,;-14.29,-8.62,;-8.13,-.62,;-7.36,.71,;-5.85,1.03,;-5.69,2.56,;-4.36,3.33,;-4.36,4.87,;-3.02,2.56,;-1.69,3.33,;-1.69,4.87,;-.36,5.64,;.98,4.87,;.98,3.33,;-.36,2.56,;-.36,1.02,;2.31,2.56,;2.31,1.02,;3.64,.25,;4.98,1.02,;4.98,2.56,;6.31,3.33,;7.64,2.56,;7.64,1.02,;8.98,3.33,;9.14,4.87,;10.65,5.19,;11.42,6.52,;12.96,6.52,;13.73,7.85,;15.27,7.85,;16.6,7.08,;16.6,8.62,;13.73,5.19,;12.96,3.85,;11.42,3.85,;10.39,2.71,;10.78,1.22,;3.64,3.33,;3.64,4.87,)|

BDBM468446

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:39.44,wD:36.37,(15.93,7.57,;14.39,7.57,;13.62,8.91,;13.62,6.24,;14.39,4.9,;13.62,3.57,;12.08,3.57,;11.31,4.9,;12.08,6.24,;9.81,4.58,;9.65,3.05,;8.31,2.28,;8.31,.74,;6.98,3.05,;5.64,2.28,;5.64,.74,;4.31,-.03,;2.98,.74,;2.98,2.28,;4.31,3.05,;4.31,4.59,;1.64,3.05,;1.64,4.59,;.31,5.36,;-1.02,4.59,;-1.02,3.05,;-2.36,2.28,;-3.69,3.05,;-3.69,4.59,;-5.03,2.28,;-5.19,.75,;-6.69,.43,;-7.46,-.9,;-9,-.9,;-9.77,-2.24,;-11.31,-2.24,;-12.08,-3.57,;-13.62,-3.57,;-14.39,-4.9,;-13.62,-6.24,;-12.08,-6.24,;-11.31,-4.9,;-14.39,-7.57,;-15.93,-7.57,;-13.62,-8.91,;-9.77,.43,;-9,1.76,;-7.46,1.76,;-6.43,2.91,;-6.83,4.4,;.31,2.28,;.31,.74,;11.05,2.43,;11.45,.94,)|

BDBM468447

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC2)c1Cl |r,wU:11.14,wD:8.7,(-6.83,4.29,;-6.43,2.81,;-7.46,1.66,;-9,1.66,;-9.77,.33,;-9,-1.01,;-9.77,-2.34,;-11.31,-2.34,;-12.08,-3.67,;-13.62,-3.67,;-14.39,-5.01,;-13.62,-6.34,;-12.08,-6.34,;-11.31,-5.01,;-14.39,-7.67,;-15.93,-7.67,;-13.62,-9.01,;-7.46,-1.01,;-6.69,.33,;-5.19,.65,;-5.03,2.18,;-3.69,2.95,;-3.69,4.49,;-2.36,2.18,;-1.02,2.95,;-1.02,4.49,;.31,5.26,;1.64,4.49,;1.64,2.95,;.31,2.18,;.31,.64,;2.98,2.18,;2.98,.64,;4.31,-.13,;5.64,.64,;5.64,2.18,;6.98,2.95,;8.31,2.18,;8.31,.64,;9.65,2.95,;9.81,4.48,;11.31,4.8,;12.08,6.13,;13.62,6.13,;14.39,4.8,;13.62,3.47,;12.08,3.47,;11.05,2.32,;11.45,.84,;14.39,7.47,;15.93,7.47,;15.93,9.01,;14.39,9.01,;4.31,2.95,;4.31,4.49,)|

BDBM468448

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCCC2)c1Cl |r,wU:11.14,wD:8.7,(-6.99,3.84,;-6.59,2.36,;-7.62,1.21,;-9.16,1.21,;-9.93,-.12,;-9.16,-1.45,;-9.93,-2.79,;-11.47,-2.79,;-12.24,-4.12,;-13.78,-4.12,;-14.55,-5.46,;-13.78,-6.79,;-12.24,-6.79,;-11.47,-5.46,;-14.55,-8.12,;-16.09,-8.12,;-13.78,-9.46,;-7.62,-1.45,;-6.85,-.12,;-5.34,.2,;-5.18,1.73,;-3.85,2.5,;-3.85,4.04,;-2.51,1.73,;-1.18,2.5,;-1.18,4.04,;.15,4.81,;1.49,4.04,;1.49,2.5,;.15,1.73,;.15,.19,;2.82,1.73,;2.82,.19,;4.15,-.58,;5.49,.19,;5.49,1.73,;6.82,2.5,;8.16,1.73,;8.16,.19,;9.49,2.5,;9.65,4.03,;11.16,4.35,;11.93,5.69,;13.47,5.69,;14.24,4.35,;13.47,3.02,;11.93,3.02,;10.9,1.87,;11.3,.39,;14.24,7.02,;15.77,7.18,;16.09,8.69,;14.76,9.46,;13.61,8.43,;4.15,2.5,;4.15,4.04,)|

BDBM468449

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCCCC2)c1Cl |r,wU:11.14,wD:8.7,(-7.22,3.73,;-6.82,2.24,;-7.85,1.1,;-9.39,1.1,;-10.16,-.24,;-9.39,-1.57,;-10.16,-2.9,;-11.7,-2.9,;-12.47,-4.24,;-14.01,-4.24,;-14.78,-5.57,;-14.01,-6.9,;-12.47,-6.9,;-11.7,-5.57,;-14.78,-8.24,;-16.32,-8.24,;-14.01,-9.57,;-7.85,-1.57,;-7.08,-.24,;-5.57,.08,;-5.41,1.62,;-4.08,2.39,;-4.08,3.93,;-2.74,1.62,;-1.41,2.39,;-1.41,3.93,;-.08,4.7,;1.26,3.93,;1.26,2.39,;-.08,1.62,;-.08,.08,;2.59,1.62,;2.59,.08,;3.93,-.69,;5.26,.08,;5.26,1.62,;6.59,2.39,;7.93,1.62,;7.93,.08,;9.26,2.39,;9.42,3.92,;10.93,4.24,;11.7,5.57,;13.24,5.57,;14.01,4.24,;13.24,2.9,;11.7,2.9,;10.67,1.76,;11.07,.27,;14.01,6.9,;15.55,6.9,;16.32,8.24,;15.55,9.57,;14.01,9.57,;13.24,8.24,;3.93,2.39,;3.93,3.93,)|

BDBM468450

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl |r,wU:11.14,wD:8.7,(-7.22,3.73,;-6.82,2.24,;-7.85,1.1,;-9.39,1.1,;-10.16,-.24,;-9.39,-1.57,;-10.16,-2.9,;-11.7,-2.9,;-12.47,-4.24,;-14.01,-4.24,;-14.78,-5.57,;-14.01,-6.9,;-12.47,-6.9,;-11.7,-5.57,;-14.78,-8.24,;-16.32,-8.24,;-14.01,-9.57,;-7.85,-1.57,;-7.08,-.24,;-5.57,.08,;-5.41,1.62,;-4.08,2.39,;-4.08,3.93,;-2.74,1.62,;-1.41,2.39,;-1.41,3.93,;-.08,4.7,;1.26,3.93,;1.26,2.39,;-.08,1.62,;-.08,.08,;2.59,1.62,;2.59,.08,;3.93,-.69,;5.26,.08,;5.26,1.62,;6.59,2.39,;7.93,1.62,;7.93,.08,;9.26,2.39,;9.42,3.92,;10.93,4.24,;11.7,5.57,;13.24,5.57,;14.01,4.24,;13.24,2.9,;11.7,2.9,;10.67,1.76,;11.07,.27,;14.01,6.9,;15.55,6.9,;16.32,8.24,;15.55,9.57,;14.01,9.57,;13.24,8.24,;3.93,2.39,;3.93,3.93,)|

BDBM468451

Cn1c2CCN(CCO)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:41.47,wD:38.40,(10.99,.92,;10.67,2.43,;11.7,3.57,;13.24,3.57,;14.01,4.9,;13.24,6.24,;14.01,7.57,;15.55,7.57,;16.32,8.91,;11.7,6.24,;10.93,4.9,;9.42,4.58,;9.26,3.05,;7.93,2.28,;7.93,.74,;6.59,3.05,;5.26,2.28,;5.26,.74,;3.93,-.03,;2.59,.74,;2.59,2.28,;3.93,3.05,;3.93,4.59,;1.26,3.05,;1.26,4.59,;-.08,5.36,;-1.41,4.59,;-1.41,3.05,;-2.74,2.28,;-4.08,3.05,;-4.08,4.59,;-5.41,2.28,;-5.57,.75,;-7.08,.43,;-7.85,-.9,;-9.39,-.9,;-10.16,-2.24,;-11.7,-2.24,;-12.47,-3.57,;-14.01,-3.57,;-14.78,-4.9,;-14.01,-6.24,;-12.47,-6.24,;-11.7,-4.9,;-14.78,-7.57,;-16.32,-7.57,;-14.01,-8.91,;-10.16,.43,;-9.39,1.76,;-7.85,1.76,;-6.82,2.91,;-7.14,4.42,;-.08,2.28,;-.08,.74,)|

BDBM468452

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:40.45,wD:37.38,1.1,(16.32,8.91,;15.55,7.57,;16.32,6.24,;14.01,7.57,;13.24,6.24,;14.01,4.9,;13.24,3.57,;11.7,3.57,;10.93,4.9,;11.7,6.24,;9.42,4.58,;9.26,3.05,;7.93,2.28,;7.93,.74,;6.59,3.05,;5.26,2.28,;5.26,.74,;3.93,-.03,;2.59,.74,;2.59,2.28,;3.93,3.05,;3.93,4.59,;1.26,3.05,;1.26,4.59,;-.08,5.36,;-1.41,4.59,;-1.41,3.05,;-2.74,2.28,;-4.08,3.05,;-4.08,4.59,;-5.41,2.28,;-5.57,.75,;-7.08,.43,;-7.85,-.9,;-9.39,-.9,;-10.16,-2.24,;-11.7,-2.24,;-12.47,-3.57,;-14.01,-3.57,;-14.78,-4.9,;-14.01,-6.24,;-12.47,-6.24,;-11.7,-4.9,;-14.78,-7.57,;-16.32,-7.57,;-14.01,-8.91,;-10.16,.43,;-9.39,1.76,;-7.85,1.76,;-6.82,2.91,;-7.22,4.4,;-.08,2.28,;-.08,.74,;10.67,2.43,;11.07,.94,)|

BDBM468453

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:40.45,1.1,wD:37.38,(16.32,8.91,;15.55,7.57,;16.32,6.24,;14.01,7.57,;13.24,6.24,;14.01,4.9,;13.24,3.57,;11.7,3.57,;10.93,4.9,;11.7,6.24,;9.42,4.58,;9.26,3.05,;7.93,2.28,;7.93,.74,;6.59,3.05,;5.26,2.28,;5.26,.74,;3.93,-.03,;2.59,.74,;2.59,2.28,;3.93,3.05,;3.93,4.59,;1.26,3.05,;1.26,4.59,;-.08,5.36,;-1.41,4.59,;-1.41,3.05,;-2.74,2.28,;-4.08,3.05,;-4.08,4.59,;-5.41,2.28,;-5.57,.75,;-7.08,.43,;-7.85,-.9,;-9.39,-.9,;-10.16,-2.24,;-11.7,-2.24,;-12.47,-3.57,;-14.01,-3.57,;-14.78,-4.9,;-14.01,-6.24,;-12.47,-6.24,;-11.7,-4.9,;-14.78,-7.57,;-16.32,-7.57,;-14.01,-8.91,;-10.16,.43,;-9.39,1.76,;-7.85,1.76,;-6.82,2.91,;-7.22,4.4,;-.08,2.28,;-.08,.74,;10.67,2.43,;11.07,.94,)|

BDBM468454

Cn1c2CCN(CCc3ccc(cc3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl

BDBM468455

Cn1c2CCN(Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(CC2)C(O)=O)c1Cl)C1CCOCC1 |(9.91,-.4,;9.51,1.09,;10.54,2.24,;12.08,2.24,;12.85,3.57,;12.08,4.9,;10.54,4.9,;9.77,3.57,;8.27,3.25,;8.11,1.72,;6.77,.95,;6.77,-.59,;5.44,1.72,;4.1,.95,;4.1,-.59,;2.77,-1.36,;1.44,-.59,;1.44,.95,;2.77,1.72,;2.77,3.26,;.1,1.72,;.1,3.26,;-1.23,4.03,;-2.56,3.26,;-2.56,1.72,;-3.9,.95,;-5.23,1.72,;-5.23,3.26,;-6.57,.95,;-6.73,-.58,;-8.23,-.9,;-9,-2.24,;-10.54,-2.24,;-11.31,-.9,;-10.54,.43,;-9,.43,;-7.97,1.57,;-8.37,3.06,;-11.31,-3.57,;-12.85,-3.57,;-13.62,-4.9,;-12.85,-6.24,;-11.31,-6.24,;-10.54,-4.9,;-13.62,-7.57,;-15.16,-7.57,;-12.85,-8.91,;-1.23,.95,;-1.23,-.59,;12.85,6.24,;14.39,6.24,;15.16,7.57,;14.39,8.91,;12.85,8.91,;12.08,7.57,)|

BDBM468456

Cn1c2CCN(Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)c1Cl)C1CCOCC1 |(9.5,-.44,;9.1,1.05,;10.13,2.19,;11.67,2.19,;12.44,3.53,;11.67,4.86,;10.13,4.86,;9.36,3.53,;7.85,3.2,;7.69,1.67,;6.36,.9,;6.36,-.64,;5.03,1.67,;3.69,.9,;3.69,-.64,;2.36,-1.41,;1.03,-.64,;1.03,.9,;2.36,1.67,;2.36,3.21,;-.31,1.67,;-.31,3.21,;-1.64,3.98,;-2.98,3.21,;-2.98,1.67,;-4.31,.9,;-5.64,1.67,;-5.64,3.21,;-6.98,.9,;-7.14,-.63,;-8.64,-.95,;-9.41,-2.28,;-10.95,-2.28,;-11.72,-.95,;-10.95,.39,;-9.41,.39,;-8.38,1.53,;-8.78,3.02,;-11.72,-3.62,;-13.26,-3.62,;-14.03,-4.95,;-13.26,-6.28,;-14.75,-6.68,;-11.72,-6.28,;-10.95,-4.95,;-12.87,-7.77,;-13.95,-8.86,;-11.38,-8.17,;-1.64,.9,;-1.64,-.64,;12.44,6.19,;13.98,6.19,;14.75,7.53,;13.98,8.86,;12.44,8.86,;11.67,7.53,)|

BDBM468457

CCC1(CCC(CC1)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCOCC3)c1Cl)n2C)C(O)=O |(-15.3,-5.59,;-14.21,-6.68,;-12.72,-6.28,;-13.49,-4.95,;-12.72,-3.62,;-11.18,-3.62,;-10.41,-4.95,;-11.18,-6.28,;-10.41,-2.28,;-11.18,-.95,;-10.41,.39,;-8.87,.39,;-8.1,-.95,;-8.87,-2.28,;-6.59,-.63,;-6.43,.9,;-5.1,1.67,;-5.1,3.21,;-3.76,.9,;-2.43,1.67,;-2.43,3.21,;-1.1,3.98,;.24,3.21,;.24,1.67,;-1.1,.9,;-1.1,-.64,;1.57,.9,;1.57,-.64,;2.9,-1.41,;4.24,-.64,;4.24,.9,;5.57,1.67,;6.9,.9,;6.9,-.64,;8.24,1.67,;8.4,3.2,;9.91,3.53,;10.68,4.86,;12.22,4.86,;12.99,3.53,;12.22,2.19,;10.68,2.19,;9.65,1.05,;9.97,-.46,;12.99,6.19,;14.53,6.19,;15.3,7.53,;14.53,8.86,;12.99,8.86,;12.22,7.53,;2.9,1.67,;2.9,3.21,;-7.84,1.53,;-8.16,3.04,;-12.32,-7.77,;-13.41,-8.86,;-10.83,-8.17,)|

BDBM468458

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:37.42,wD:34.35,(15.16,8.24,;14.39,6.9,;15.16,5.57,;14.39,4.24,;12.85,4.24,;12.08,5.57,;12.85,6.9,;10.58,5.25,;10.42,3.72,;9.08,2.95,;9.08,1.41,;7.75,3.72,;6.41,2.95,;6.41,1.41,;5.08,.64,;3.75,1.41,;3.75,2.95,;5.08,3.72,;5.08,5.26,;2.41,3.72,;2.41,5.26,;1.08,6.03,;-.25,5.26,;-.25,3.72,;-1.59,2.95,;-2.92,3.72,;-2.92,5.26,;-4.26,2.95,;-4.42,1.42,;-5.92,1.1,;-6.69,-.24,;-8.23,-.24,;-9,-1.57,;-10.54,-1.57,;-11.31,-2.9,;-12.85,-2.9,;-13.62,-4.24,;-12.85,-5.57,;-11.31,-5.57,;-10.54,-4.24,;-13.62,-6.9,;-15.16,-6.9,;-12.85,-8.24,;-9,1.1,;-8.23,2.43,;-6.69,2.43,;-5.66,3.58,;-5.98,5.08,;1.08,2.95,;1.08,1.41,;11.82,3.09,;12.14,1.59,)|

BDBM468459

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc5ccc(cc5)C(O)=O)CCc4n3C)c1C)n2C

BDBM468460

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1C)n2C

BDBM468461

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(CC6)C(O)=O)CCc4n3C)c1C)n2C

BDBM468462

CCC1(CCC(CC1)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1Cl)n2C)C(O)=O |(-14.14,-4.26,;-13.05,-5.35,;-11.56,-4.95,;-12.33,-3.62,;-11.56,-2.28,;-10.02,-2.28,;-9.25,-3.62,;-10.02,-4.95,;-9.25,-.95,;-10.02,.39,;-9.25,1.72,;-7.71,1.72,;-6.94,.39,;-7.71,-.95,;-5.44,.71,;-5.28,2.24,;-3.94,3.01,;-3.94,4.55,;-2.61,2.24,;-1.28,3.01,;-1.28,4.55,;.06,5.32,;1.39,4.55,;1.39,3.01,;.06,2.24,;.06,.7,;2.73,2.24,;2.73,.7,;4.06,-.07,;5.39,.7,;5.39,2.24,;6.73,3.01,;8.06,2.24,;8.06,.7,;9.39,3.01,;9.55,4.54,;11.06,4.86,;11.83,6.19,;13.37,6.19,;14.14,7.53,;14.14,4.86,;13.37,3.53,;11.83,3.53,;10.8,2.38,;11.12,.87,;4.06,3.01,;4.06,4.55,;-6.68,2.86,;-7,4.37,;-11.17,-6.44,;-12.25,-7.53,;-9.68,-6.84,)|

BDBM468463

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCC(C)(CC3)C(O)=O)c1C)n2C |(14.37,7.53,;12.83,7.53,;12.06,6.19,;12.83,4.86,;12.06,3.53,;10.52,3.53,;9.75,4.86,;10.52,6.19,;8.24,4.54,;8.08,3.01,;6.75,2.24,;6.75,.7,;5.41,3.01,;4.08,2.24,;4.08,.7,;2.74,-.07,;1.41,.7,;1.41,2.24,;2.74,3.01,;2.74,4.55,;.08,3.01,;.08,4.55,;-1.26,5.32,;-2.59,4.55,;-2.59,3.01,;-3.92,2.24,;-5.26,3.01,;-5.26,4.55,;-6.59,2.24,;-6.75,.71,;-8.26,.39,;-9.03,-.95,;-10.57,-.95,;-11.34,.39,;-10.57,1.72,;-9.03,1.72,;-8,2.86,;-8.32,4.37,;-11.34,-2.28,;-12.88,-2.28,;-13.65,-3.62,;-12.88,-4.95,;-14.37,-5.35,;-11.34,-4.95,;-10.57,-3.62,;-12.48,-6.44,;-13.57,-7.53,;-10.99,-6.84,;-1.26,2.24,;-1.26,.7,;9.49,2.38,;9.81,.87,)|

BDBM468464

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCC(C)(CC3)C(O)=O)c1C)n2C |(11.7,8.12,;12.47,6.78,;14.01,6.78,;11.7,5.45,;12.47,4.11,;11.7,2.78,;10.16,2.78,;9.39,4.11,;10.16,5.45,;7.88,3.79,;7.72,2.26,;6.39,1.49,;6.39,-.05,;5.05,2.26,;3.72,1.49,;3.72,-.05,;2.39,-.82,;1.05,-.05,;1.05,1.49,;2.39,2.26,;2.39,3.8,;-.28,2.26,;-.28,3.8,;-1.62,4.57,;-2.95,3.8,;-2.95,2.26,;-4.28,1.49,;-5.62,2.26,;-5.62,3.8,;-6.95,1.49,;-7.11,-.04,;-8.62,-.36,;-9.39,-1.69,;-10.93,-1.69,;-11.7,-.36,;-10.93,.98,;-9.39,.98,;-8.36,2.12,;-9.13,3.45,;-11.7,-3.03,;-13.24,-3.03,;-14.01,-4.36,;-13.24,-5.69,;-14.01,-7.03,;-11.7,-5.69,;-10.93,-4.36,;-12.47,-7.03,;-13.56,-8.12,;-10.98,-7.43,;-1.62,1.49,;-1.62,-.05,;9.13,1.64,;9.9,.3,)|

BDBM468465

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCCCC2)c1Cl |(-2,-.71,;-2,.83,;-3.33,1.6,;-4.67,.83,;-6,1.6,;-6,3.14,;-7.34,.83,;-7.5,-.71,;-9,-1.03,;-9.77,-2.36,;-11.31,-2.36,;-12.08,-1.03,;-11.31,.31,;-9.77,.31,;-8.74,1.45,;-9.51,2.79,;-12.08,-3.69,;-13.62,-3.69,;-14.39,-5.03,;-13.62,-6.36,;-14.39,-7.69,;-12.08,-6.36,;-11.31,-5.03,;-12.85,-7.69,;-13.94,-8.78,;-11.37,-8.09,;-3.33,3.14,;-2,3.91,;-.67,3.14,;-.67,1.6,;.67,.83,;.67,-.71,;2,-1.48,;3.33,-.71,;3.33,.83,;4.67,1.6,;6,.83,;6,-.71,;7.34,1.6,;7.5,3.13,;9,3.45,;9.77,4.78,;11.31,4.78,;12.08,3.45,;11.31,2.11,;9.77,2.11,;8.74,.97,;9.51,-.36,;12.08,6.12,;13.62,6.12,;14.39,7.45,;13.62,8.78,;12.08,8.78,;11.31,7.45,;2,1.6,;2,3.14,)|

BDBM468466

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl |(-2,-.71,;-2,.83,;-3.33,1.6,;-4.67,.83,;-6,1.6,;-6,3.14,;-7.34,.83,;-7.5,-.71,;-9,-1.03,;-9.77,-2.36,;-11.31,-2.36,;-12.08,-1.03,;-11.31,.31,;-9.77,.31,;-8.74,1.45,;-9.51,2.79,;-12.08,-3.69,;-13.62,-3.69,;-14.39,-5.03,;-13.62,-6.36,;-14.39,-7.69,;-12.08,-6.36,;-11.31,-5.03,;-12.85,-7.69,;-13.94,-8.78,;-11.37,-8.09,;-3.33,3.14,;-2,3.91,;-.67,3.14,;-.67,1.6,;.67,.83,;.67,-.71,;2,-1.48,;3.33,-.71,;3.33,.83,;4.67,1.6,;6,.83,;6,-.71,;7.34,1.6,;7.5,3.13,;9,3.45,;9.77,4.78,;11.31,4.78,;12.08,3.45,;11.31,2.11,;9.77,2.11,;8.74,.97,;9.51,-.36,;12.08,6.12,;13.62,6.12,;14.39,7.45,;13.62,8.78,;12.08,8.78,;11.31,7.45,;2,1.6,;2,3.14,)|

BDBM468467

Cc1c(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl |r,wU:16.19,wD:13.12,(-.08,.08,;-.08,1.62,;-1.41,2.39,;-2.74,1.62,;-4.08,2.39,;-4.08,3.93,;-5.41,1.62,;-5.57,.08,;-7.08,-.24,;-7.85,-1.57,;-9.39,-1.57,;-10.16,-2.9,;-11.7,-2.9,;-12.47,-4.24,;-14.01,-4.24,;-14.78,-5.57,;-14.01,-6.9,;-12.47,-6.9,;-11.7,-5.57,;-14.78,-8.24,;-16.32,-8.24,;-14.01,-9.57,;-10.16,-.24,;-9.39,1.1,;-7.85,1.1,;-6.82,2.24,;-7.14,3.75,;-1.41,3.93,;-.08,4.7,;1.26,3.93,;1.26,2.39,;2.59,1.62,;2.59,.08,;3.93,-.69,;5.26,.08,;5.26,1.62,;6.59,2.39,;7.93,1.62,;7.93,.08,;9.26,2.39,;9.42,3.92,;10.93,4.24,;11.7,5.57,;13.24,5.57,;14.01,4.24,;13.24,2.9,;11.7,2.9,;10.67,1.76,;10.99,.25,;14.01,6.9,;15.55,6.9,;16.32,8.24,;15.55,9.57,;14.01,9.57,;13.24,8.24,;3.93,2.39,;3.93,3.93,)|

BDBM468468

Cc1c(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl |r,wU:15.18,wD:12.11,(.31,-2.59,;.31,-1.05,;-1.02,-.28,;-2.36,-1.05,;-3.69,-.28,;-3.69,1.26,;-5.03,-1.05,;-5.19,-2.58,;-6.69,-2.9,;-7.46,-4.24,;-9,-4.24,;-9.77,-5.57,;-11.31,-5.57,;-12.08,-4.24,;-13.62,-4.24,;-14.39,-5.57,;-13.62,-6.9,;-12.08,-6.9,;-15.93,-5.57,;-16.7,-4.24,;-16.7,-6.9,;-9.77,-2.9,;-9,-1.57,;-7.46,-1.57,;-6.43,-.43,;-7.2,.91,;-1.02,1.26,;.31,2.03,;1.64,1.26,;1.64,-.28,;2.98,-1.05,;2.98,-2.59,;4.31,-3.36,;5.64,-2.59,;5.64,-1.05,;6.98,-.28,;8.31,-1.05,;8.31,-2.59,;9.65,-.28,;9.81,1.25,;11.31,1.57,;12.08,2.9,;13.62,2.9,;14.39,1.57,;13.62,.24,;12.08,.24,;11.05,-.91,;11.82,-2.24,;14.39,4.24,;15.93,4.24,;16.7,5.57,;15.93,6.9,;14.39,6.9,;13.62,5.57,;4.31,-.28,;4.31,1.26,)|

BDBM468469

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(CC2)C(O)=O)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl |(-1.23,-.59,;-1.23,.95,;-2.56,1.72,;-3.9,.95,;-5.23,1.72,;-5.23,3.26,;-6.57,.95,;-6.73,-.58,;-8.23,-.9,;-9,-2.24,;-10.54,-2.24,;-11.31,-.9,;-10.54,.43,;-9,.43,;-7.97,1.58,;-8.74,2.91,;-11.31,-3.57,;-12.85,-3.57,;-13.62,-4.9,;-12.85,-6.24,;-11.31,-6.24,;-10.54,-4.9,;-13.62,-7.57,;-15.16,-7.57,;-12.85,-8.91,;-2.56,3.26,;-1.23,4.03,;.1,3.26,;.1,1.72,;1.44,.95,;1.44,-.59,;2.77,-1.36,;4.1,-.59,;4.1,.95,;5.44,1.72,;6.77,.95,;6.77,-.59,;8.11,1.72,;8.27,3.25,;9.77,3.57,;10.54,4.9,;12.08,4.9,;12.85,3.57,;12.08,2.24,;10.54,2.24,;9.51,1.09,;10.28,-.24,;12.85,6.24,;14.39,6.24,;15.16,7.57,;14.39,8.91,;12.85,8.91,;12.08,7.57,;2.77,1.72,;2.77,3.26,)|

BDBM468470

CCC1(CCC(CC1)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCOCC3)c1Cl)n2C)C(O)=O |(-15.3,-5.59,;-14.21,-6.68,;-12.72,-6.28,;-13.49,-4.95,;-12.72,-3.62,;-11.18,-3.62,;-10.41,-4.95,;-11.18,-6.28,;-10.41,-2.28,;-11.18,-.95,;-10.41,.39,;-8.87,.39,;-8.1,-.95,;-8.87,-2.28,;-6.59,-.63,;-6.43,.9,;-5.1,1.67,;-5.1,3.21,;-3.76,.9,;-2.43,1.67,;-2.43,3.21,;-1.1,3.98,;.24,3.21,;.24,1.67,;-1.1,.9,;-1.1,-.64,;1.57,.9,;1.57,-.64,;2.9,-1.41,;4.24,-.64,;4.24,.9,;5.57,1.67,;6.9,.9,;6.9,-.64,;8.24,1.67,;8.4,3.2,;9.91,3.53,;10.68,4.86,;12.22,4.86,;12.99,3.53,;12.22,2.19,;10.68,2.19,;9.65,1.05,;9.97,-.46,;12.99,6.19,;14.53,6.19,;15.3,7.53,;14.53,8.86,;12.99,8.86,;12.22,7.53,;2.9,1.67,;2.9,3.21,;-7.84,1.53,;-8.16,3.04,;-12.32,-7.77,;-13.41,-8.86,;-10.83,-8.17,)|

BDBM468471

Cc1c(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CNCCc3n2C)c1Cl |r,wU:12.11,15.18,(1.46,-1.26,;1.46,.28,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-5.57,;-12.47,-5.57,;-13.24,-4.24,;-12.47,-2.9,;-10.93,-2.9,;-14.78,-4.24,;-15.55,-5.57,;-15.55,-2.9,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;.13,2.59,;1.46,3.36,;2.8,2.59,;2.8,1.05,;4.13,.28,;4.13,-1.26,;5.47,-2.03,;6.8,-1.26,;6.8,.28,;8.13,1.05,;9.47,.28,;9.47,-1.26,;10.8,1.05,;10.96,2.58,;12.47,2.9,;13.24,4.24,;14.78,4.24,;15.55,2.9,;14.78,1.57,;13.24,1.57,;12.21,.43,;12.53,-1.08,;5.47,1.05,;5.47,2.59,)|

BDBM468472

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1C)n2C |r,wU:33.34,36.41,(15.55,5.57,;14.78,4.24,;15.55,2.9,;14.78,1.57,;13.24,1.57,;12.47,2.9,;13.24,4.24,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;5.47,1.05,;5.47,2.59,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-5.57,;-12.47,-5.57,;-13.24,-4.24,;-12.47,-2.9,;-10.93,-2.9,;-14.78,-4.24,;-15.55,-2.9,;-15.55,-5.57,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;1.46,.28,;1.46,-1.26,;12.21,.43,;12.53,-1.08,)|

BDBM468473

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:37.42,wD:34.35,(15.16,8.24,;14.39,6.9,;15.16,5.57,;14.39,4.24,;12.85,4.24,;12.08,5.57,;12.85,6.9,;10.58,5.25,;10.42,3.72,;9.08,2.95,;9.08,1.41,;7.75,3.72,;6.41,2.95,;6.41,1.41,;5.08,.64,;3.75,1.41,;3.75,2.95,;5.08,3.72,;5.08,5.26,;2.41,3.72,;2.41,5.26,;1.08,6.03,;-.25,5.26,;-.25,3.72,;-1.59,2.95,;-2.92,3.72,;-2.92,5.26,;-4.26,2.95,;-4.42,1.42,;-5.92,1.1,;-6.69,-.24,;-8.23,-.24,;-9,-1.57,;-10.54,-1.57,;-11.31,-2.9,;-12.85,-2.9,;-13.62,-4.24,;-12.85,-5.57,;-11.31,-5.57,;-10.54,-4.24,;-13.62,-6.9,;-15.16,-6.9,;-12.85,-8.24,;-9,1.1,;-8.23,2.43,;-6.69,2.43,;-5.66,3.58,;-5.98,5.08,;1.08,2.95,;1.08,1.41,;11.82,3.09,;12.14,1.59,)|

BDBM468475

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.41,wD:33.34,(15.55,5.57,;14.78,4.24,;15.55,2.9,;14.78,1.57,;13.24,1.57,;12.47,2.9,;13.24,4.24,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;5.47,1.05,;5.47,2.59,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-2.9,;-12.47,-2.9,;-13.24,-4.24,;-12.47,-5.57,;-10.93,-5.57,;-14.78,-4.24,;-15.55,-2.9,;-15.55,-5.57,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-6.05,2.24,;1.46,.28,;1.46,-1.26,;12.21,.43,;12.98,-.91,)|

BDBM468476

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc5ccc(cc5)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM468478

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCC(C)(CC3)C(O)=O)c1Cl)n2C |(13.24,7.45,;12.47,6.12,;13.24,4.78,;12.47,3.45,;10.93,3.45,;10.16,4.78,;10.93,6.12,;8.65,4.46,;8.49,2.93,;7.16,2.16,;7.16,.62,;5.82,2.93,;4.49,2.16,;4.49,.62,;3.16,-.15,;1.82,.62,;1.82,2.16,;3.16,2.93,;3.16,4.47,;.49,2.93,;.49,4.47,;-.85,5.24,;-2.18,4.47,;-2.18,2.93,;-3.51,2.16,;-4.85,2.93,;-4.85,4.47,;-6.18,2.16,;-6.34,.63,;-7.85,.31,;-8.62,-1.03,;-10.16,-1.03,;-10.93,.31,;-10.16,1.64,;-8.62,1.64,;-7.59,2.79,;-8.36,4.12,;-10.93,-2.36,;-12.47,-2.36,;-13.24,-3.69,;-12.47,-5.03,;-13.24,-6.36,;-10.93,-5.03,;-10.16,-3.69,;-11.7,-6.36,;-12.79,-7.45,;-10.21,-6.76,;-.85,2.16,;-.85,.62,;9.9,2.3,;10.67,.97,)|

BDBM468479

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM468480

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CC5CC[C@](C)(CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.42,wD:36.38,(15.73,6.03,;14.96,4.7,;15.73,3.37,;14.96,2.03,;13.42,2.03,;12.65,3.37,;13.42,4.7,;11.14,3.05,;10.98,1.51,;9.65,.74,;9.65,-.8,;8.31,1.51,;6.98,.74,;6.98,-.8,;5.64,-1.57,;4.31,-.8,;4.31,.74,;5.64,1.51,;5.64,3.05,;2.98,1.51,;2.98,3.05,;1.64,3.82,;.31,3.05,;.31,1.51,;-1.02,.74,;-2.36,1.51,;-2.36,3.05,;-3.69,.74,;-3.85,-.79,;-5.36,-1.11,;-6.13,-2.44,;-7.67,-2.44,;-8.44,-3.78,;-9.98,-3.78,;-10.75,-5.11,;-12.29,-5.11,;-13.06,-3.78,;-14.39,-3.01,;-12.29,-2.44,;-10.75,-2.44,;-14.39,-4.55,;-15.73,-3.78,;-13.99,-6.03,;-8.44,-1.11,;-7.67,.23,;-6.13,.23,;-5.1,1.37,;-5.87,2.7,;1.64,.74,;1.64,-.8,;12.39,.89,;13.16,-.45,)|

BDBM468481

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CC5CC[C@](C)(CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.38,wD:36.42,(15.73,6.03,;14.96,4.7,;15.73,3.37,;14.96,2.03,;13.42,2.03,;12.65,3.37,;13.42,4.7,;11.14,3.05,;10.98,1.51,;9.65,.74,;9.65,-.8,;8.31,1.51,;6.98,.74,;6.98,-.8,;5.64,-1.57,;4.31,-.8,;4.31,.74,;5.64,1.51,;5.64,3.05,;2.98,1.51,;2.98,3.05,;1.64,3.82,;.31,3.05,;.31,1.51,;-1.02,.74,;-2.36,1.51,;-2.36,3.05,;-3.69,.74,;-3.85,-.79,;-5.36,-1.11,;-6.13,-2.44,;-7.67,-2.44,;-8.44,-3.78,;-9.98,-3.78,;-10.75,-2.44,;-12.29,-2.44,;-13.06,-3.78,;-14.39,-3.01,;-12.29,-5.11,;-10.75,-5.11,;-14.39,-4.55,;-15.73,-3.78,;-13.99,-6.03,;-8.44,-1.11,;-7.67,.23,;-6.13,.23,;-5.1,1.37,;-5.87,2.7,;1.64,.74,;1.64,-.8,;12.39,.89,;13.16,-.45,)|

BDBM468482

CCC1(CCC(CC1)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C)CCc4n3C)c1C)n2C)C(O)=O |(-14.14,-4.26,;-13.05,-5.35,;-11.56,-4.95,;-12.33,-3.62,;-11.56,-2.28,;-10.02,-2.28,;-9.25,-3.62,;-10.02,-4.95,;-9.25,-.95,;-10.02,.39,;-9.25,1.72,;-7.71,1.72,;-6.94,.39,;-7.71,-.95,;-5.44,.71,;-5.28,2.24,;-3.94,3.01,;-3.94,4.55,;-2.61,2.24,;-1.28,3.01,;-1.28,4.55,;.06,5.32,;1.39,4.55,;1.39,3.01,;.06,2.24,;.06,.7,;2.73,2.24,;2.73,.7,;4.06,-.07,;5.39,.7,;5.39,2.24,;6.73,3.01,;8.06,2.24,;8.06,.7,;9.39,3.01,;9.55,4.54,;11.06,4.86,;11.83,6.19,;13.37,6.19,;14.14,7.53,;14.14,4.86,;13.37,3.53,;11.83,3.53,;10.8,2.38,;11.12,.87,;4.06,3.01,;4.06,4.55,;-6.68,2.86,;-7,4.37,;-11.17,-6.44,;-12.25,-7.53,;-9.68,-6.84,)|

BDBM468483

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:44.51,wD:41.44,(3.93,3.93,;3.93,2.39,;5.26,1.62,;6.59,2.39,;7.93,1.62,;7.93,.08,;9.26,2.39,;9.42,3.92,;10.93,4.24,;11.7,5.57,;13.24,5.57,;14.01,4.24,;13.24,2.9,;11.7,2.9,;10.67,1.76,;10.99,.25,;14.01,6.9,;15.55,6.9,;16.32,8.24,;15.55,9.57,;14.01,9.57,;13.24,8.24,;5.26,.08,;3.93,-.69,;2.59,.08,;2.59,1.62,;1.26,2.39,;1.26,3.93,;-.08,4.7,;-1.41,3.93,;-1.41,2.39,;-2.74,1.62,;-4.08,2.39,;-4.08,3.93,;-5.41,1.62,;-5.57,.08,;-7.08,-.24,;-7.85,-1.57,;-9.39,-1.57,;-10.16,-2.9,;-11.7,-2.9,;-12.47,-4.24,;-14.01,-4.24,;-14.78,-5.57,;-14.01,-6.9,;-12.47,-6.9,;-11.7,-5.57,;-14.78,-8.24,;-16.32,-8.24,;-14.01,-9.57,;-10.16,-.24,;-9.39,1.1,;-7.85,1.1,;-6.82,2.24,;-7.14,3.75,;-.08,1.62,;-.08,.08,)|

BDBM468484

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:43.50,wD:40.43,(4.31,1.26,;4.31,-.28,;5.64,-1.05,;6.98,-.28,;8.31,-1.05,;8.31,-2.59,;9.65,-.28,;9.81,1.25,;11.31,1.57,;12.08,2.9,;13.62,2.9,;14.39,1.57,;13.62,.24,;12.08,.24,;11.05,-.91,;11.82,-2.24,;14.39,4.24,;15.93,4.24,;16.7,5.57,;15.93,6.9,;14.39,6.9,;13.62,5.57,;5.64,-2.59,;4.31,-3.36,;2.98,-2.59,;2.98,-1.05,;1.64,-.28,;1.64,1.26,;.31,2.03,;-1.02,1.26,;-1.02,-.28,;-2.36,-1.05,;-3.69,-.28,;-3.69,1.26,;-5.03,-1.05,;-5.19,-2.58,;-6.69,-2.9,;-7.46,-4.24,;-9,-4.24,;-9.77,-5.57,;-11.31,-5.57,;-12.08,-4.24,;-13.62,-4.24,;-14.39,-5.57,;-13.62,-6.9,;-12.08,-6.9,;-15.93,-5.57,;-16.7,-4.24,;-16.7,-6.9,;-9.77,-2.9,;-9,-1.57,;-7.46,-1.57,;-6.43,-.43,;-7.2,.91,;.31,-1.05,;.31,-2.59,)|

BDBM468486

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCc4ccc(cc4)C(O)=O)CCc3n2C)c1Cl

BDBM468487

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(CC2)C(O)=O)c1Cl |(2.77,3.26,;2.77,1.72,;4.1,.95,;5.44,1.72,;6.77,.95,;6.77,-.59,;8.11,1.72,;8.27,3.25,;9.77,3.57,;10.54,4.9,;12.08,4.9,;12.85,3.57,;12.08,2.24,;10.54,2.24,;9.51,1.09,;10.28,-.24,;12.85,6.24,;14.39,6.24,;15.16,7.57,;14.39,8.91,;12.85,8.91,;12.08,7.57,;4.1,-.59,;2.77,-1.36,;1.44,-.59,;1.44,.95,;.1,1.72,;.1,3.26,;-1.23,4.03,;-2.56,3.26,;-2.56,1.72,;-3.9,.95,;-5.23,1.72,;-5.23,3.26,;-6.57,.95,;-6.73,-.58,;-8.23,-.9,;-9,-2.24,;-10.54,-2.24,;-11.31,-.9,;-10.54,.43,;-9,.43,;-7.97,1.58,;-8.74,2.91,;-11.31,-3.57,;-12.85,-3.57,;-13.62,-4.9,;-12.85,-6.24,;-11.31,-6.24,;-10.54,-4.9,;-13.62,-7.57,;-15.16,-7.57,;-12.85,-8.91,;-1.23,.95,;-1.23,-.59,)|

BDBM468488

Cc1c(NC(=O)c2nc3CNCCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:38.44,wD:35.37,(5.08,5.93,;5.08,4.39,;6.41,3.62,;7.75,4.39,;9.08,3.62,;9.08,2.08,;10.42,4.39,;10.58,5.92,;12.08,6.24,;12.85,7.57,;14.39,7.57,;15.16,6.24,;14.39,4.9,;12.85,4.9,;11.82,3.76,;12.14,2.25,;6.41,2.08,;5.08,1.31,;3.75,2.08,;3.75,3.62,;2.41,4.39,;2.41,5.93,;1.08,6.7,;-.25,5.93,;-.25,4.39,;-1.59,3.62,;-2.92,4.39,;-2.92,5.93,;-4.26,3.62,;-4.42,2.08,;-5.92,1.76,;-6.69,.43,;-8.23,.43,;-9,-.9,;-10.54,-.9,;-11.31,-2.24,;-12.85,-2.24,;-13.62,-3.57,;-12.85,-4.9,;-11.31,-4.9,;-10.54,-3.57,;-13.62,-6.24,;-15.16,-6.24,;-12.85,-7.57,;-9,1.76,;-8.23,3.1,;-6.69,3.1,;-5.66,4.24,;-5.98,5.75,;1.08,3.62,;1.08,2.08,)|

BDBM468489

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:38.43,wD:35.36,(15.93,8.24,;14.39,8.24,;13.62,6.9,;14.39,5.57,;13.62,4.24,;12.08,4.24,;11.31,5.57,;12.08,6.9,;9.81,5.25,;9.65,3.72,;8.31,2.95,;8.31,1.41,;6.98,3.72,;5.64,2.95,;5.64,1.41,;4.31,.64,;2.98,1.41,;2.98,2.95,;4.31,3.72,;4.31,5.26,;1.64,3.72,;1.64,5.26,;.31,6.03,;-1.02,5.26,;-1.02,3.72,;-2.36,2.95,;-3.69,3.72,;-3.69,5.26,;-5.03,2.95,;-5.19,1.42,;-6.69,1.1,;-7.46,-.24,;-9,-.24,;-9.77,-1.57,;-11.31,-1.57,;-12.08,-2.9,;-13.62,-2.9,;-14.39,-4.24,;-13.62,-5.57,;-12.08,-5.57,;-11.31,-4.24,;-14.39,-6.9,;-15.93,-6.9,;-13.62,-8.24,;-9.77,1.1,;-9,2.43,;-7.46,2.43,;-6.43,3.58,;-6.75,5.08,;.31,2.95,;.31,1.41,;11.05,3.09,;11.37,1.59,)|

BDBM468490

Cc1c(NC(=O)c2nc3CN(CC4CC4)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:42.49,wD:39.42,(3.64,4.87,;3.64,3.33,;4.98,2.56,;6.31,3.33,;7.64,2.56,;7.64,1.02,;8.98,3.33,;9.14,4.87,;10.65,5.19,;11.42,6.52,;12.96,6.52,;13.73,7.85,;15.27,7.85,;16.6,7.08,;16.6,8.62,;13.73,5.19,;12.96,3.85,;11.42,3.85,;10.39,2.71,;11.16,1.37,;4.98,1.02,;3.64,.25,;2.31,1.02,;2.31,2.56,;.98,3.33,;.98,4.87,;-.36,5.64,;-1.69,4.87,;-1.69,3.33,;-3.02,2.56,;-4.36,3.33,;-4.36,4.87,;-5.69,2.56,;-5.85,1.03,;-7.36,.71,;-8.13,-.62,;-9.67,-.62,;-10.44,-1.95,;-11.98,-1.95,;-12.75,-3.29,;-14.29,-3.29,;-15.06,-4.62,;-14.29,-5.96,;-12.75,-5.96,;-11.98,-4.62,;-15.06,-7.29,;-16.6,-7.29,;-14.29,-8.62,;-10.44,.71,;-9.67,2.05,;-8.13,2.05,;-7.1,3.19,;-7.87,4.52,;-.36,2.56,;-.36,1.02,)|

BDBM468491

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:39.44,wD:36.37,(15.93,7.57,;14.39,7.57,;13.62,8.91,;13.62,6.24,;14.39,4.9,;13.62,3.57,;12.08,3.57,;11.31,4.9,;12.08,6.24,;9.81,4.58,;9.65,3.05,;8.31,2.28,;8.31,.74,;6.98,3.05,;5.64,2.28,;5.64,.74,;4.31,-.03,;2.98,.74,;2.98,2.28,;4.31,3.05,;4.31,4.59,;1.64,3.05,;1.64,4.59,;.31,5.36,;-1.02,4.59,;-1.02,3.05,;-2.36,2.28,;-3.69,3.05,;-3.69,4.59,;-5.03,2.28,;-5.19,.75,;-6.69,.43,;-7.46,-.9,;-9,-.9,;-9.77,-2.24,;-11.31,-2.24,;-12.08,-3.57,;-13.62,-3.57,;-14.39,-4.9,;-13.62,-6.24,;-12.08,-6.24,;-11.31,-4.9,;-14.39,-7.57,;-15.93,-7.57,;-13.62,-8.91,;-9.77,.43,;-9,1.76,;-7.46,1.76,;-6.43,2.91,;-7.2,4.24,;.31,2.28,;.31,.74,;11.05,2.43,;11.82,1.09,)|

BDBM468492

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:43.50,wD:40.43,(4.07,4.07,;4.07,2.53,;5.41,1.76,;6.74,2.53,;8.07,1.76,;8.07,.22,;9.41,2.53,;9.57,4.07,;11.07,4.39,;11.84,5.72,;13.38,5.72,;14.15,4.39,;13.38,3.05,;11.84,3.05,;10.81,1.91,;11.58,.57,;14.15,7.05,;15.69,7.05,;16.17,8.52,;14.92,9.42,;13.68,8.52,;5.41,.22,;4.07,-.55,;2.74,.22,;2.74,1.76,;1.41,2.53,;1.41,4.07,;.07,4.84,;-1.26,4.07,;-1.26,2.53,;-2.6,1.76,;-3.93,2.53,;-3.93,4.07,;-5.26,1.76,;-5.42,.23,;-6.93,-.09,;-7.7,-1.42,;-9.24,-1.42,;-10.01,-2.75,;-11.55,-2.75,;-12.32,-4.09,;-13.86,-4.09,;-14.63,-5.42,;-13.86,-6.76,;-12.32,-6.76,;-11.55,-5.42,;-14.63,-8.09,;-16.17,-8.09,;-13.86,-9.42,;-10.01,-.09,;-9.24,1.25,;-7.7,1.25,;-6.67,2.39,;-7.44,3.72,;.07,1.76,;.07,.22,)|

BDBM468493

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCCCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:44.51,wD:41.44,(3.93,3.93,;3.93,2.39,;5.26,1.62,;6.59,2.39,;7.93,1.62,;7.93,.08,;9.26,2.39,;9.42,3.92,;10.93,4.24,;11.7,5.57,;13.24,5.57,;14.01,4.24,;13.24,2.9,;11.7,2.9,;10.67,1.76,;11.44,.43,;14.01,6.9,;15.55,6.9,;16.32,8.24,;15.55,9.57,;14.01,9.57,;13.24,8.24,;5.26,.08,;3.93,-.69,;2.59,.08,;2.59,1.62,;1.26,2.39,;1.26,3.93,;-.08,4.7,;-1.41,3.93,;-1.41,2.39,;-2.74,1.62,;-4.08,2.39,;-4.08,3.93,;-5.41,1.62,;-5.57,.08,;-7.08,-.24,;-7.85,-1.57,;-9.39,-1.57,;-10.16,-2.9,;-11.7,-2.9,;-12.47,-4.24,;-14.01,-4.24,;-14.78,-5.57,;-14.01,-6.9,;-12.47,-6.9,;-11.7,-5.57,;-14.78,-8.24,;-16.32,-8.24,;-14.01,-9.57,;-10.16,-.24,;-9.39,1.1,;-7.85,1.1,;-6.82,2.24,;-7.59,3.58,;-.08,1.62,;-.08,.08,)|

BDBM468494

Cc1c(NC(=O)c2nc3CN(CCO)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:41.47,wD:38.40,(3.93,4.59,;3.93,3.05,;5.26,2.28,;6.59,3.05,;7.93,2.28,;7.93,.74,;9.26,3.05,;9.42,4.58,;10.93,4.9,;11.7,6.24,;13.24,6.24,;14.01,7.57,;15.55,7.57,;16.32,8.91,;14.01,4.9,;13.24,3.57,;11.7,3.57,;10.67,2.43,;10.99,.92,;5.26,.74,;3.93,-.03,;2.59,.74,;2.59,2.28,;1.26,3.05,;1.26,4.59,;-.08,5.36,;-1.41,4.59,;-1.41,3.05,;-2.74,2.28,;-4.08,3.05,;-4.08,4.59,;-5.41,2.28,;-5.57,.75,;-7.08,.43,;-7.85,-.9,;-9.39,-.9,;-10.16,-2.24,;-11.7,-2.24,;-12.47,-3.57,;-14.01,-3.57,;-14.78,-4.9,;-14.01,-6.24,;-12.47,-6.24,;-11.7,-4.9,;-14.78,-7.57,;-16.32,-7.57,;-14.01,-8.91,;-10.16,.43,;-9.39,1.76,;-7.85,1.76,;-6.82,2.91,;-7.14,4.42,;-.08,2.28,;-.08,.74,)|

BDBM468495

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:40.45,1.1,wD:37.38,(16.32,6.24,;15.55,7.57,;16.32,8.91,;14.01,7.57,;13.24,6.24,;14.01,4.9,;13.24,3.57,;11.7,3.57,;10.93,4.9,;11.7,6.24,;9.42,4.58,;9.26,3.05,;7.93,2.28,;7.93,.74,;6.59,3.05,;5.26,2.28,;5.26,.74,;3.93,-.03,;2.59,.74,;2.59,2.28,;3.93,3.05,;3.93,4.59,;1.26,3.05,;1.26,4.59,;-.08,5.36,;-1.41,4.59,;-1.41,3.05,;-2.74,2.28,;-4.08,3.05,;-4.08,4.59,;-5.41,2.28,;-5.57,.75,;-7.08,.43,;-7.85,-.9,;-9.39,-.9,;-10.16,-2.24,;-11.7,-2.24,;-12.47,-3.57,;-14.01,-3.57,;-14.78,-4.9,;-14.01,-6.24,;-12.47,-6.24,;-11.7,-4.9,;-14.78,-7.57,;-16.32,-7.57,;-14.01,-8.91,;-10.16,.43,;-9.39,1.76,;-7.85,1.76,;-6.82,2.91,;-7.59,4.24,;-.08,2.28,;-.08,.74,;10.67,2.43,;11.44,1.09,)|

BDBM468496

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:45.52,wD:42.45,(3.93,3.26,;3.93,1.72,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;10.99,-.41,;14.01,6.24,;15.55,6.24,;16.32,7.57,;15.55,8.91,;16.32,10.24,;14.01,8.91,;13.24,7.57,;5.26,-.59,;3.93,-1.36,;2.59,-.59,;2.59,.95,;1.26,1.72,;1.26,3.26,;-.08,4.03,;-1.41,3.26,;-1.41,1.72,;-2.74,.95,;-4.08,1.72,;-4.08,3.26,;-5.41,.95,;-5.57,-.58,;-7.08,-.9,;-7.85,-2.24,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-14.01,-4.9,;-14.78,-6.24,;-14.01,-7.57,;-12.47,-7.57,;-11.7,-6.24,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-10.16,-.9,;-9.39,.43,;-7.85,.43,;-6.82,1.58,;-7.14,3.08,;-.08,.95,;-.08,-.59,)|

BDBM468497

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wD:42.45,45.52,(3.93,3.26,;3.93,1.72,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;10.99,-.41,;14.01,6.24,;15.55,6.24,;16.32,7.57,;15.55,8.91,;16.32,10.24,;14.01,8.91,;13.24,7.57,;5.26,-.59,;3.93,-1.36,;2.59,-.59,;2.59,.95,;1.26,1.72,;1.26,3.26,;-.08,4.03,;-1.41,3.26,;-1.41,1.72,;-2.74,.95,;-4.08,1.72,;-4.08,3.26,;-5.41,.95,;-5.57,-.58,;-7.08,-.9,;-7.85,-2.24,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-14.01,-4.9,;-14.78,-6.24,;-14.01,-7.57,;-12.47,-7.57,;-11.7,-6.24,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-10.16,-.9,;-9.39,.43,;-7.85,.43,;-6.82,1.58,;-7.14,3.08,;-.08,.95,;-.08,-.59,)|

BDBM468498

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:33.34,36.41,(15.55,5.57,;14.78,4.24,;15.55,2.9,;14.78,1.57,;13.24,1.57,;12.47,2.9,;13.24,4.24,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;5.47,1.05,;5.47,2.59,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-5.57,;-12.47,-5.57,;-13.24,-4.24,;-12.47,-2.9,;-10.93,-2.9,;-14.78,-4.24,;-15.55,-2.9,;-15.55,-5.57,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;1.46,.28,;1.46,-1.26,;12.21,.43,;12.53,-1.08,)|

BDBM468499

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:40.43,43.50,(4.31,1.26,;4.31,-.28,;5.64,-1.05,;6.98,-.28,;8.31,-1.05,;8.31,-2.59,;9.65,-.28,;9.81,1.25,;11.31,1.57,;12.08,2.9,;13.62,2.9,;14.39,1.57,;13.62,.24,;12.08,.24,;11.05,-.91,;11.37,-2.41,;14.39,4.24,;15.93,4.24,;16.7,5.57,;15.93,6.9,;14.39,6.9,;13.62,5.57,;5.64,-2.59,;4.31,-3.36,;2.98,-2.59,;2.98,-1.05,;1.64,-.28,;1.64,1.26,;.31,2.03,;-1.02,1.26,;-1.02,-.28,;-2.36,-1.05,;-3.69,-.28,;-3.69,1.26,;-5.03,-1.05,;-5.19,-2.58,;-6.69,-2.9,;-7.46,-4.24,;-9,-4.24,;-9.77,-5.57,;-11.31,-5.57,;-12.08,-6.9,;-13.62,-6.9,;-14.39,-5.57,;-13.62,-4.24,;-12.08,-4.24,;-15.93,-5.57,;-16.7,-6.9,;-16.7,-4.24,;-9.77,-2.9,;-9,-1.57,;-7.46,-1.57,;-6.43,-.43,;-6.75,1.08,;.31,-1.05,;.31,-2.59,)|

BDBM468501

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C |r,wU:36.37,39.44,1.1,(16.7,6.24,;15.93,4.9,;16.7,3.57,;14.39,4.9,;13.62,3.57,;14.39,2.24,;13.62,.9,;12.08,.9,;11.31,2.24,;12.08,3.57,;9.81,1.92,;9.65,.39,;8.31,-.38,;8.31,-1.92,;6.98,.39,;5.64,-.38,;5.64,-1.92,;4.31,-2.69,;2.98,-1.92,;2.98,-.38,;4.31,.39,;4.31,1.93,;1.64,.39,;1.64,1.93,;.31,2.7,;-1.02,1.93,;-1.02,.39,;-2.36,-.38,;-3.69,.39,;-3.69,1.93,;-5.03,-.38,;-5.19,-1.92,;-6.69,-2.24,;-7.46,-3.57,;-9,-3.57,;-9.77,-4.9,;-11.31,-4.9,;-12.08,-6.24,;-13.62,-6.24,;-14.39,-4.9,;-13.62,-3.57,;-12.08,-3.57,;-15.93,-4.9,;-16.7,-6.24,;-16.7,-3.57,;-9.77,-2.24,;-9,-.9,;-7.46,-.9,;-6.43,.24,;-7.2,1.58,;.31,-.38,;.31,-1.92,;11.05,-.24,;11.82,-1.58,)|

BDBM468502

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:41.44,44.51,(4.31,.59,;4.31,-.95,;5.64,-1.72,;6.98,-.95,;8.31,-1.72,;8.31,-3.26,;9.65,-.95,;9.81,.58,;11.31,.9,;12.08,2.24,;13.62,2.24,;14.39,.9,;13.62,-.43,;12.08,-.43,;11.05,-1.58,;11.37,-3.08,;14.39,3.57,;15.93,3.57,;16.7,4.9,;15.93,6.24,;16.7,7.57,;14.39,6.24,;13.62,4.9,;5.64,-3.26,;4.31,-4.03,;2.98,-3.26,;2.98,-1.72,;1.64,-.95,;1.64,.59,;.31,1.36,;-1.02,.59,;-1.02,-.95,;-2.36,-1.72,;-3.69,-.95,;-3.69,.59,;-5.03,-1.72,;-5.19,-3.25,;-6.69,-3.57,;-7.46,-4.9,;-9,-4.9,;-9.77,-6.24,;-11.31,-6.24,;-12.08,-7.57,;-13.62,-7.57,;-14.39,-6.24,;-13.62,-4.9,;-12.08,-4.9,;-15.93,-6.24,;-16.7,-7.57,;-16.7,-4.9,;-9.77,-3.57,;-9,-2.24,;-7.46,-2.24,;-6.43,-1.09,;-6.75,.41,;.31,-1.72,;.31,-3.26,)|

BDBM468503

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:41.44,wD:44.51,(4.31,.59,;4.31,-.95,;5.64,-1.72,;6.98,-.95,;8.31,-1.72,;8.31,-3.26,;9.65,-.95,;9.81,.58,;11.31,.9,;12.08,2.24,;13.62,2.24,;14.39,.9,;13.62,-.43,;12.08,-.43,;11.05,-1.58,;11.37,-3.08,;14.39,3.57,;15.93,3.57,;16.7,4.9,;15.93,6.24,;16.7,7.57,;14.39,6.24,;13.62,4.9,;5.64,-3.26,;4.31,-4.03,;2.98,-3.26,;2.98,-1.72,;1.64,-.95,;1.64,.59,;.31,1.36,;-1.02,.59,;-1.02,-.95,;-2.36,-1.72,;-3.69,-.95,;-3.69,.59,;-5.03,-1.72,;-5.19,-3.25,;-6.69,-3.57,;-7.46,-4.9,;-9,-4.9,;-9.77,-6.24,;-11.31,-6.24,;-12.08,-7.57,;-13.62,-7.57,;-14.39,-6.24,;-13.62,-4.9,;-12.08,-4.9,;-15.93,-6.24,;-16.7,-7.57,;-16.7,-4.9,;-9.77,-3.57,;-9,-2.24,;-7.46,-2.24,;-6.43,-1.09,;-6.75,.41,;.31,-1.72,;.31,-3.26,)|

BDBM468504

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCCCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)c1Cl |(2.28,3.21,;2.28,1.67,;3.62,.9,;4.95,1.67,;6.28,.9,;6.28,-.64,;7.62,1.67,;7.78,3.2,;9.28,3.53,;10.05,4.86,;11.59,4.86,;12.36,3.53,;11.59,2.19,;10.05,2.19,;9.02,1.05,;9.34,-.46,;12.36,6.19,;13.9,6.19,;14.67,7.53,;13.9,8.86,;12.36,8.86,;11.59,7.53,;3.62,-.64,;2.28,-1.41,;.95,-.64,;.95,.9,;-.38,1.67,;-.38,3.21,;-1.72,3.98,;-3.05,3.21,;-3.05,1.67,;-4.39,.9,;-5.72,1.67,;-5.72,3.21,;-7.05,.9,;-7.21,-.63,;-8.72,-.95,;-9.49,-2.28,;-11.03,-2.28,;-11.8,-.95,;-11.03,.39,;-9.49,.39,;-8.46,1.53,;-8.78,3.04,;-11.8,-3.62,;-13.34,-3.62,;-14.11,-4.95,;-13.34,-6.28,;-14.67,-7.05,;-11.8,-6.28,;-11.03,-4.95,;-12.94,-7.77,;-11.45,-8.17,;-14.03,-8.86,;-1.72,.9,;-1.72,-.64,)|

BDBM468505

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)c1Cl |(2,2.59,;2,1.05,;3.33,.28,;4.67,1.05,;6,.28,;6,-1.26,;7.34,1.05,;7.5,2.58,;9,2.9,;9.77,4.24,;11.31,4.24,;12.08,2.9,;11.31,1.57,;9.77,1.57,;8.74,.43,;9.51,-.91,;12.08,5.57,;13.62,5.57,;14.39,6.9,;13.62,8.24,;14.39,9.57,;12.08,8.24,;11.31,6.9,;3.33,-1.26,;2,-2.03,;.67,-1.26,;.67,.28,;-.67,1.05,;-.67,2.59,;-2,3.36,;-3.33,2.59,;-3.33,1.05,;-4.67,.28,;-6,1.05,;-6,2.59,;-7.34,.28,;-7.5,-1.25,;-9,-1.57,;-9.77,-2.9,;-11.31,-2.9,;-12.08,-1.57,;-11.31,-.24,;-9.77,-.24,;-8.74,.91,;-9.51,2.24,;-12.08,-4.24,;-13.62,-4.24,;-14.39,-5.57,;-13.62,-6.9,;-14.39,-8.24,;-12.08,-6.9,;-11.31,-5.57,;-12.85,-8.24,;-11.37,-8.64,;-13.62,-9.57,;-2,.28,;-2,-1.26,)|

BDBM468506

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCC(C)(CC3)C(O)=O)c1Cl)n2C |r,wD:1.1,(14.39,5.57,;13.62,6.9,;14.39,8.24,;12.08,6.9,;11.31,5.57,;12.08,4.24,;11.31,2.9,;9.77,2.9,;9,4.24,;9.77,5.57,;7.5,3.92,;7.34,2.39,;6,1.62,;6,.08,;4.67,2.39,;3.33,1.62,;3.33,.08,;2,-.69,;.67,.08,;.67,1.62,;2,2.39,;2,3.93,;-.67,2.39,;-.67,3.93,;-2,4.7,;-3.33,3.93,;-3.33,2.39,;-4.67,1.62,;-6,2.39,;-6,3.93,;-7.34,1.62,;-7.5,.08,;-9,-.24,;-9.77,-1.57,;-11.31,-1.57,;-12.08,-.24,;-11.31,1.1,;-9.77,1.1,;-8.74,2.24,;-9.51,3.58,;-12.08,-2.9,;-13.62,-2.9,;-14.39,-4.24,;-13.62,-5.57,;-14.39,-6.9,;-12.08,-5.57,;-11.31,-4.24,;-12.85,-6.9,;-11.37,-7.3,;-13.62,-8.24,;-2,1.62,;-2,.08,;8.74,1.76,;9.51,.43,)|

BDBM468507

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CC[C@](C)(CC2)C(O)=O)c1Cl |r,wU:47.57,wD:47.53,(2.28,3.21,;2.28,1.67,;3.62,.9,;4.95,1.67,;6.28,.9,;6.28,-.64,;7.62,1.67,;7.78,3.2,;9.28,3.53,;10.05,4.86,;11.59,4.86,;12.36,3.53,;11.59,2.19,;10.05,2.19,;9.02,1.05,;9.34,-.46,;12.36,6.19,;13.9,6.19,;14.67,7.53,;13.9,8.86,;12.36,8.86,;11.59,7.53,;3.62,-.64,;2.28,-1.41,;.95,-.64,;.95,.9,;-.38,1.67,;-.38,3.21,;-1.72,3.98,;-3.05,3.21,;-3.05,1.67,;-4.39,.9,;-5.72,1.67,;-5.72,3.21,;-7.05,.9,;-7.21,-.63,;-8.72,-.95,;-9.49,-2.28,;-11.03,-2.28,;-11.8,-.95,;-11.03,.39,;-9.49,.39,;-8.46,1.53,;-8.78,3.04,;-11.8,-3.62,;-11.03,-4.95,;-11.8,-6.28,;-13.34,-6.28,;-14.67,-7.05,;-14.11,-4.95,;-13.34,-3.62,;-12.94,-7.77,;-11.45,-8.17,;-14.03,-8.86,;-1.72,.9,;-1.72,-.64,)|

BDBM468509

Cc1c(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CC[C@](C)(CC2)C(O)=O)c1Cl |r,wU:47.53,wD:47.57,(2.28,3.21,;2.28,1.67,;3.62,.9,;4.95,1.67,;6.28,.9,;6.28,-.64,;7.62,1.67,;7.78,3.2,;9.28,3.53,;10.05,4.86,;11.59,4.86,;12.36,3.53,;11.59,2.19,;10.05,2.19,;9.02,1.05,;9.34,-.46,;12.36,6.19,;13.9,6.19,;14.67,7.53,;13.9,8.86,;12.36,8.86,;11.59,7.53,;3.62,-.64,;2.28,-1.41,;.95,-.64,;.95,.9,;-.38,1.67,;-.38,3.21,;-1.72,3.98,;-3.05,3.21,;-3.05,1.67,;-4.39,.9,;-5.72,1.67,;-5.72,3.21,;-7.05,.9,;-7.21,-.63,;-8.72,-.95,;-9.49,-2.28,;-11.03,-2.28,;-11.8,-.95,;-11.03,.39,;-9.49,.39,;-8.46,1.53,;-8.78,3.04,;-11.8,-3.62,;-13.34,-3.62,;-14.11,-4.95,;-13.34,-6.28,;-14.67,-7.05,;-11.8,-6.28,;-11.03,-4.95,;-12.94,-7.77,;-11.45,-8.17,;-14.03,-8.86,;-1.72,.9,;-1.72,-.64,)|

BDBM468510

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CC[C@](C)(CC3)C(O)=O)c1Cl)n2C |r,wU:43.51,1.1,wD:43.47,(14.9,5.26,;14.13,6.6,;14.9,7.93,;12.59,6.6,;11.68,5.35,;12.31,3.95,;11.4,2.7,;9.87,2.86,;9.25,4.27,;10.15,5.51,;7.71,4.11,;7.39,2.6,;6.06,1.83,;6.06,.29,;4.73,2.6,;3.39,1.83,;3.39,.29,;2.06,-.48,;.73,.29,;.73,1.83,;2.06,2.6,;2.06,4.14,;-.61,2.6,;-.61,4.14,;-1.94,4.91,;-3.28,4.14,;-3.28,2.6,;-4.61,1.83,;-5.94,2.6,;-5.94,4.14,;-7.28,1.83,;-7.44,.3,;-8.94,-.02,;-9.71,-1.35,;-11.25,-1.35,;-12.02,-.02,;-11.25,1.31,;-9.71,1.31,;-8.68,2.46,;-9,3.96,;-12.02,-2.69,;-11.25,-4.02,;-12.02,-5.36,;-13.56,-5.36,;-14.9,-6.13,;-14.33,-4.02,;-13.56,-2.69,;-13.17,-6.84,;-11.68,-7.24,;-14.25,-7.93,;-1.94,1.83,;-1.94,.29,;8.73,1.83,;8.89,.3,)|

BDBM468511

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3CC[C@](C)(CC3)C(O)=O)c1Cl)n2C |r,wU:43.47,1.1,wD:43.51,(14.9,5.26,;14.13,6.6,;14.9,7.93,;12.59,6.6,;11.68,5.35,;12.31,3.95,;11.4,2.7,;9.87,2.86,;9.25,4.27,;10.15,5.51,;7.71,4.11,;7.39,2.6,;6.06,1.83,;6.06,.29,;4.73,2.6,;3.39,1.83,;3.39,.29,;2.06,-.48,;.73,.29,;.73,1.83,;2.06,2.6,;2.06,4.14,;-.61,2.6,;-.61,4.14,;-1.94,4.91,;-3.28,4.14,;-3.28,2.6,;-4.61,1.83,;-5.94,2.6,;-5.94,4.14,;-7.28,1.83,;-7.44,.3,;-8.94,-.02,;-9.71,-1.35,;-11.25,-1.35,;-12.02,-.02,;-11.25,1.31,;-9.71,1.31,;-8.68,2.46,;-9,3.96,;-12.02,-2.69,;-13.56,-2.69,;-14.33,-4.02,;-13.56,-5.36,;-14.9,-6.13,;-12.02,-5.36,;-11.25,-4.02,;-13.17,-6.84,;-11.68,-7.24,;-14.25,-7.93,;-1.94,1.83,;-1.94,.29,;8.73,1.83,;8.89,.3,)|

BDBM468512

Cn1c2CCN(C[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |r,wU:10.13,wD:7.6,(-6.75,.41,;-6.43,-1.09,;-7.46,-2.24,;-9,-2.24,;-9.77,-3.57,;-9,-4.9,;-9.77,-6.24,;-11.31,-6.24,;-12.08,-4.9,;-13.62,-4.9,;-14.39,-6.24,;-13.62,-7.57,;-12.08,-7.57,;-15.93,-6.24,;-16.7,-4.9,;-16.7,-7.57,;-7.46,-4.9,;-6.69,-3.57,;-5.19,-3.25,;-5.03,-1.72,;-3.69,-.95,;-3.69,.59,;-2.36,-1.72,;-1.02,-.95,;-1.02,.59,;.31,1.36,;1.64,.59,;1.64,-.95,;.31,-1.72,;.31,-3.26,;2.98,-1.72,;2.98,-3.26,;4.31,-4.03,;5.64,-3.26,;5.64,-1.72,;6.98,-.95,;8.31,-1.72,;8.31,-3.26,;9.65,-.95,;9.81,.58,;11.31,.9,;12.08,2.24,;13.62,2.24,;14.39,.9,;13.62,-.43,;12.08,-.43,;11.05,-1.58,;11.37,-3.08,;14.39,3.57,;15.93,3.57,;16.7,4.9,;15.93,6.24,;16.7,7.57,;14.39,6.24,;13.62,4.9,;4.31,-.95,;4.31,.59,)|

BDBM468513

Cn1c2CCN(C[C@H]3CC[C@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |r,wD:7.6,10.13,(-6.75,.41,;-6.43,-1.09,;-7.46,-2.24,;-9,-2.24,;-9.77,-3.57,;-9,-4.9,;-9.77,-6.24,;-11.31,-6.24,;-12.08,-4.9,;-13.62,-4.9,;-14.39,-6.24,;-13.62,-7.57,;-12.08,-7.57,;-15.93,-6.24,;-16.7,-4.9,;-16.7,-7.57,;-7.46,-4.9,;-6.69,-3.57,;-5.19,-3.25,;-5.03,-1.72,;-3.69,-.95,;-3.69,.59,;-2.36,-1.72,;-1.02,-.95,;-1.02,.59,;.31,1.36,;1.64,.59,;1.64,-.95,;.31,-1.72,;.31,-3.26,;2.98,-1.72,;2.98,-3.26,;4.31,-4.03,;5.64,-3.26,;5.64,-1.72,;6.98,-.95,;8.31,-1.72,;8.31,-3.26,;9.65,-.95,;9.81,.58,;11.31,.9,;12.08,2.24,;13.62,2.24,;14.39,.9,;13.62,-.43,;12.08,-.43,;11.05,-1.58,;11.37,-3.08,;14.39,3.57,;15.93,3.57,;16.7,4.9,;15.93,6.24,;16.7,7.57,;14.39,6.24,;13.62,4.9,;4.31,-.95,;4.31,.59,)|

BDBM468514

Cn1c2CCN(C[C@H]3CC[C@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |r,wU:7.6,10.13,(-6.75,.41,;-6.43,-1.09,;-7.46,-2.24,;-9,-2.24,;-9.77,-3.57,;-9,-4.9,;-9.77,-6.24,;-11.31,-6.24,;-12.08,-7.57,;-13.62,-7.57,;-14.39,-6.24,;-13.62,-4.9,;-12.08,-4.9,;-15.93,-6.24,;-16.7,-4.9,;-16.7,-7.57,;-7.46,-4.9,;-6.69,-3.57,;-5.19,-3.25,;-5.03,-1.72,;-3.69,-.95,;-3.69,.59,;-2.36,-1.72,;-1.02,-.95,;-1.02,.59,;.31,1.36,;1.64,.59,;1.64,-.95,;.31,-1.72,;.31,-3.26,;2.98,-1.72,;2.98,-3.26,;4.31,-4.03,;5.64,-3.26,;5.64,-1.72,;6.98,-.95,;8.31,-1.72,;8.31,-3.26,;9.65,-.95,;9.81,.58,;11.31,.9,;12.08,2.24,;13.62,2.24,;14.39,.9,;13.62,-.43,;12.08,-.43,;11.05,-1.58,;11.37,-3.08,;14.39,3.57,;15.93,3.57,;16.7,4.9,;15.93,6.24,;16.7,7.57,;14.39,6.24,;13.62,4.9,;4.31,-.95,;4.31,.59,)|

BDBM468515

Cn1c2CCN(C[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |r,wU:7.6,wD:10.13,(-6.75,.41,;-6.43,-1.09,;-7.46,-2.24,;-9,-2.24,;-9.77,-3.57,;-9,-4.9,;-9.77,-6.24,;-11.31,-6.24,;-12.08,-7.57,;-13.62,-7.57,;-14.39,-6.24,;-13.62,-4.9,;-12.08,-4.9,;-15.93,-6.24,;-16.7,-4.9,;-16.7,-7.57,;-7.46,-4.9,;-6.69,-3.57,;-5.19,-3.25,;-5.03,-1.72,;-3.69,-.95,;-3.69,.59,;-2.36,-1.72,;-1.02,-.95,;-1.02,.59,;.31,1.36,;1.64,.59,;1.64,-.95,;.31,-1.72,;.31,-3.26,;2.98,-1.72,;2.98,-3.26,;4.31,-4.03,;5.64,-3.26,;5.64,-1.72,;6.98,-.95,;8.31,-1.72,;8.31,-3.26,;9.65,-.95,;9.81,.58,;11.31,.9,;12.08,2.24,;13.62,2.24,;14.39,.9,;13.62,-.43,;12.08,-.43,;11.05,-1.58,;11.37,-3.08,;14.39,3.57,;15.93,3.57,;16.7,4.9,;15.93,6.24,;16.7,7.57,;14.39,6.24,;13.62,4.9,;4.31,-.95,;4.31,.59,)|

BDBM468516

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |r,wU:11.14,wD:8.7,(-7.14,3.08,;-6.82,1.58,;-7.85,.43,;-9.39,.43,;-10.16,-.9,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-14.01,-4.9,;-14.78,-6.24,;-14.01,-7.57,;-12.47,-7.57,;-11.7,-6.24,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-7.85,-2.24,;-7.08,-.9,;-5.57,-.58,;-5.41,.95,;-4.08,1.72,;-4.08,3.26,;-2.74,.95,;-1.41,1.72,;-1.41,3.26,;-.08,4.03,;1.26,3.26,;1.26,1.72,;-.08,.95,;-.08,-.59,;2.59,.95,;2.59,-.59,;3.93,-1.36,;5.26,-.59,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;10.99,-.41,;14.01,6.24,;15.55,6.24,;16.32,7.57,;15.55,8.91,;16.32,10.24,;14.01,8.91,;13.24,7.57,;3.93,1.72,;3.93,3.26,)|

BDBM468517

Cn1c2CCN(CC[C@H]3CC[C@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |r,wD:8.7,11.14,(-7.14,3.08,;-6.82,1.58,;-7.85,.43,;-9.39,.43,;-10.16,-.9,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-14.01,-4.9,;-14.78,-6.24,;-14.01,-7.57,;-12.47,-7.57,;-11.7,-6.24,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-7.85,-2.24,;-7.08,-.9,;-5.57,-.58,;-5.41,.95,;-4.08,1.72,;-4.08,3.26,;-2.74,.95,;-1.41,1.72,;-1.41,3.26,;-.08,4.03,;1.26,3.26,;1.26,1.72,;-.08,.95,;-.08,-.59,;2.59,.95,;2.59,-.59,;3.93,-1.36,;5.26,-.59,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;10.99,-.41,;14.01,6.24,;15.55,6.24,;16.32,7.57,;15.55,8.91,;16.32,10.24,;14.01,8.91,;13.24,7.57,;3.93,1.72,;3.93,3.26,)|

BDBM468518

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1C#N)n2C |r,wU:36.41,wD:33.34,(15.51,5.59,;14.76,4.25,;15.54,2.93,;14.78,1.59,;13.24,1.57,;12.46,2.9,;13.22,4.24,;10.96,2.56,;10.81,1.03,;9.48,.26,;9.48,-1.28,;8.14,1.03,;6.81,.26,;6.81,-1.28,;5.47,-2.05,;4.14,-1.28,;4.14,.26,;5.47,1.03,;5.47,2.57,;2.81,1.03,;2.81,2.57,;1.47,3.34,;.14,2.57,;.14,1.03,;-1.19,.26,;-2.53,1.03,;-2.53,2.57,;-3.86,.26,;-4.02,-1.27,;-5.53,-1.59,;-6.3,-2.93,;-7.84,-2.93,;-8.61,-4.26,;-10.15,-4.26,;-10.92,-2.93,;-12.46,-2.93,;-13.23,-4.26,;-12.46,-5.59,;-10.92,-5.59,;-14.77,-4.26,;-15.54,-2.93,;-15.54,-5.59,;-8.61,-1.59,;-7.84,-.26,;-6.3,-.26,;-5.27,.89,;-5.59,2.39,;1.47,.26,;1.47,-1.28,;1.47,-2.63,;12.22,.42,;12.56,-1.09,)|

BDBM468519

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1C#N)n2C |r,wU:37.42,wD:34.35,(15.16,8.24,;14.39,6.9,;15.16,5.57,;14.39,4.24,;12.85,4.24,;12.08,5.57,;12.85,6.9,;10.58,5.25,;10.42,3.72,;9.08,2.95,;9.08,1.41,;7.75,3.72,;6.41,2.95,;6.41,1.41,;5.08,.64,;3.75,1.41,;3.75,2.95,;5.08,3.72,;5.08,5.26,;2.41,3.72,;2.41,5.26,;1.08,6.03,;-.25,5.26,;-.25,3.72,;-1.59,2.95,;-2.92,3.72,;-2.92,5.26,;-4.26,2.95,;-4.42,1.42,;-5.92,1.1,;-6.69,-.24,;-8.23,-.24,;-9,-1.57,;-10.54,-1.57,;-11.31,-2.9,;-12.85,-2.9,;-13.62,-4.24,;-12.85,-5.57,;-11.31,-5.57,;-10.54,-4.24,;-13.62,-6.9,;-15.16,-6.9,;-12.85,-8.24,;-9,1.1,;-8.23,2.43,;-6.69,2.43,;-5.66,3.58,;-5.98,5.08,;1.08,2.95,;1.08,1.41,;1.08,-.13,;11.82,3.09,;12.14,1.59,)|

BDBM468520

CN1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CN(C[C@H]6CC[C@@H](CC6)C(O)=O)CCc5n4C)c3Cl)c1C#N)n2C |r,wU:34.38,wD:31.31,(15.55,5.57,;14.78,4.24,;15.55,2.9,;14.78,1.57,;13.24,1.57,;12.47,2.9,;13.24,4.24,;10.96,2.58,;10.8,1.05,;9.47,.28,;9.47,-1.26,;8.13,1.05,;6.8,.28,;6.8,-1.26,;5.47,-2.03,;4.13,-1.26,;4.13,.28,;2.8,1.05,;2.8,2.59,;1.46,3.36,;.13,2.59,;.13,1.05,;-1.2,.28,;-2.54,1.05,;-2.54,2.59,;-3.87,.28,;-4.03,-1.25,;-5.54,-1.57,;-6.31,-2.9,;-7.85,-2.9,;-8.62,-4.24,;-10.16,-4.24,;-10.93,-2.9,;-12.47,-2.9,;-13.24,-4.24,;-12.47,-5.57,;-10.93,-5.57,;-14.78,-4.24,;-15.55,-2.9,;-15.55,-5.57,;-8.62,-1.57,;-7.85,-.24,;-6.31,-.24,;-5.28,.91,;-5.6,2.41,;1.46,.28,;1.46,-1.26,;5.47,1.05,;5.47,2.59,;5.47,4.13,;12.21,.43,;12.53,-1.08,)|

BDBM468521

CN1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CN(CC[C@H]6CC[C@@H](CC6)C(O)=O)CCc5n4C)c3Cl)c1C#N)n2C |r,wU:35.39,wD:32.32,(15.16,8.24,;14.39,6.9,;15.16,5.57,;14.39,4.24,;12.85,4.24,;12.08,5.57,;12.85,6.9,;10.58,5.25,;10.42,3.72,;9.08,2.95,;9.08,1.41,;7.75,3.72,;6.41,2.95,;6.41,1.41,;5.08,.64,;3.75,1.41,;3.75,2.95,;2.41,3.72,;2.41,5.26,;1.08,6.03,;-.25,5.26,;-.25,3.72,;-1.59,2.95,;-2.92,3.72,;-2.92,5.26,;-4.26,2.95,;-4.42,1.42,;-5.92,1.1,;-6.69,-.24,;-8.23,-.24,;-9,-1.57,;-10.54,-1.57,;-11.31,-2.9,;-12.85,-2.9,;-13.62,-4.24,;-12.85,-5.57,;-11.31,-5.57,;-10.54,-4.24,;-13.62,-6.9,;-15.16,-6.9,;-12.85,-8.24,;-9,1.1,;-8.23,2.43,;-6.69,2.43,;-5.66,3.58,;-5.98,5.08,;1.08,2.95,;1.08,1.41,;5.08,3.72,;5.08,5.26,;5.08,6.8,;11.82,3.09,;12.14,1.59,)|

BDBM468522

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CN(CC[C@H]6CC[C@@H](CC6)C(O)=O)CCc5n4C)c3Cl)c1C#N)n2C |r,wU:36.40,wD:33.33,(15.93,8.24,;14.39,8.24,;13.62,6.9,;14.39,5.57,;13.62,4.24,;12.08,4.24,;11.31,5.57,;12.08,6.9,;9.81,5.25,;9.65,3.72,;8.31,2.95,;8.31,1.41,;6.98,3.72,;5.64,2.95,;5.64,1.41,;4.31,.64,;2.98,1.41,;2.98,2.95,;1.64,3.72,;1.64,5.26,;.31,6.03,;-1.02,5.26,;-1.02,3.72,;-2.36,2.95,;-3.69,3.72,;-3.69,5.26,;-5.03,2.95,;-5.19,1.42,;-6.69,1.1,;-7.46,-.24,;-9,-.24,;-9.77,-1.57,;-11.31,-1.57,;-12.08,-2.9,;-13.62,-2.9,;-14.39,-4.24,;-13.62,-5.57,;-12.08,-5.57,;-11.31,-4.24,;-14.39,-6.9,;-15.93,-6.9,;-13.62,-8.24,;-9.77,1.1,;-9,2.43,;-7.46,2.43,;-6.43,3.58,;-7.2,4.91,;.31,2.95,;.31,1.41,;4.31,3.72,;4.31,5.26,;4.31,6.8,;11.05,3.09,;11.82,1.76,)|

BDBM468523

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CN(CC[C@H]6CC[C@@H](CC6)C(O)=O)CCc5n4C)c3Cl)c1C#N)n2C |r,wU:37.41,wD:34.34,(15.93,7.57,;14.39,7.57,;13.62,8.91,;13.62,6.24,;14.39,4.9,;13.62,3.57,;12.08,3.57,;11.31,4.9,;12.08,6.24,;9.81,4.58,;9.65,3.05,;8.31,2.28,;8.31,.74,;6.98,3.05,;5.64,2.28,;5.64,.74,;4.31,-.03,;2.98,.74,;2.98,2.28,;1.64,3.05,;1.64,4.59,;.31,5.36,;-1.02,4.59,;-1.02,3.05,;-2.36,2.28,;-3.69,3.05,;-3.69,4.59,;-5.03,2.28,;-5.19,.75,;-6.69,.43,;-7.46,-.9,;-9,-.9,;-9.77,-2.24,;-11.31,-2.24,;-12.08,-3.57,;-13.62,-3.57,;-14.39,-4.9,;-13.62,-6.24,;-12.08,-6.24,;-11.31,-4.9,;-14.39,-7.57,;-15.93,-7.57,;-13.62,-8.91,;-9.77,.43,;-9,1.76,;-7.46,1.76,;-6.43,2.91,;-7.2,4.24,;.31,2.28,;.31,.74,;4.31,3.05,;4.31,4.59,;4.31,6.13,;11.05,2.43,;11.82,1.09,)|

BDBM468524

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1C#N |r,wU:11.14,wD:8.7,(-7.59,3.58,;-6.82,2.24,;-7.85,1.1,;-9.39,1.1,;-10.16,-.24,;-9.39,-1.57,;-10.16,-2.9,;-11.7,-2.9,;-12.47,-4.24,;-14.01,-4.24,;-14.78,-5.57,;-14.01,-6.9,;-12.47,-6.9,;-11.7,-5.57,;-14.78,-8.24,;-16.32,-8.24,;-14.01,-9.57,;-7.85,-1.57,;-7.08,-.24,;-5.57,.08,;-5.41,1.62,;-4.08,2.39,;-4.08,3.93,;-2.74,1.62,;-1.41,2.39,;-1.41,3.93,;-.08,4.7,;1.26,3.93,;1.26,2.39,;-.08,1.62,;-.08,.08,;2.59,1.62,;2.59,.08,;3.93,-.69,;5.26,.08,;5.26,1.62,;6.59,2.39,;7.93,1.62,;7.93,.08,;9.26,2.39,;9.42,3.92,;10.93,4.24,;11.7,5.57,;13.24,5.57,;14.01,4.24,;13.24,2.9,;11.7,2.9,;10.67,1.76,;11.44,.43,;14.01,6.9,;15.55,6.9,;16.32,8.24,;15.55,9.57,;14.01,9.57,;13.24,8.24,;3.93,2.39,;3.93,3.93,;3.93,5.47,)|

BDBM468525

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1C#N)n2C |r,wU:38.43,wD:35.36,(15.93,8.24,;14.39,8.24,;13.62,6.9,;14.39,5.57,;13.62,4.24,;12.08,4.24,;11.31,5.57,;12.08,6.9,;9.81,5.25,;9.65,3.72,;8.31,2.95,;8.31,1.41,;6.98,3.72,;5.64,2.95,;5.64,1.41,;4.31,.64,;2.98,1.41,;2.98,2.95,;4.31,3.72,;4.31,5.26,;1.64,3.72,;1.64,5.26,;.31,6.03,;-1.02,5.26,;-1.02,3.72,;-2.36,2.95,;-3.69,3.72,;-3.69,5.26,;-5.03,2.95,;-5.19,1.42,;-6.69,1.1,;-7.46,-.24,;-9,-.24,;-9.77,-1.57,;-11.31,-1.57,;-12.08,-2.9,;-13.62,-2.9,;-14.39,-4.24,;-13.62,-5.57,;-12.08,-5.57,;-11.31,-4.24,;-14.39,-6.9,;-15.93,-6.9,;-13.62,-8.24,;-9.77,1.1,;-9,2.43,;-7.46,2.43,;-6.43,3.58,;-6.75,5.08,;.31,2.95,;.31,1.41,;.31,-.13,;11.05,3.09,;11.37,1.59,)|

BDBM468526

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1C#N)n2C |r,wU:39.44,wD:36.37,(13.62,8.91,;14.39,7.57,;15.93,7.57,;13.62,6.24,;14.39,4.9,;13.62,3.57,;12.08,3.57,;11.31,4.9,;12.08,6.24,;9.81,4.58,;9.65,3.05,;8.31,2.28,;8.31,.74,;6.98,3.05,;5.64,2.28,;5.64,.74,;4.31,-.03,;2.98,.74,;2.98,2.28,;4.31,3.05,;4.31,4.59,;1.64,3.05,;1.64,4.59,;.31,5.36,;-1.02,4.59,;-1.02,3.05,;-2.36,2.28,;-3.69,3.05,;-3.69,4.59,;-5.03,2.28,;-5.19,.75,;-6.69,.43,;-7.46,-.9,;-9,-.9,;-9.77,-2.24,;-11.31,-2.24,;-12.08,-3.57,;-13.62,-3.57,;-14.39,-4.9,;-13.62,-6.24,;-12.08,-6.24,;-11.31,-4.9,;-14.39,-7.57,;-15.93,-7.57,;-13.62,-8.91,;-9.77,.43,;-9,1.76,;-7.46,1.76,;-6.43,2.91,;-6.75,4.42,;.31,2.28,;.31,.74,;.31,-.8,;11.05,2.43,;11.37,.92,)|

BDBM468527

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@@H](CC5)C(O)=O)CCc4n3C)c1C#N)n2C |r,wU:37.42,wD:34.35,(16.32,5.57,;14.78,5.57,;14.01,4.24,;14.78,2.9,;14.01,1.57,;12.47,1.57,;11.7,2.9,;12.47,4.24,;10.19,2.58,;10.03,1.05,;8.7,.28,;8.7,-1.26,;7.36,1.05,;6.03,.28,;6.03,-1.26,;4.7,-2.03,;3.36,-1.26,;3.36,.28,;4.7,1.05,;4.7,2.59,;2.03,1.05,;2.03,2.59,;.69,3.36,;-.64,2.59,;-.64,1.05,;-1.97,.28,;-3.31,1.05,;-3.31,2.59,;-4.64,.28,;-4.8,-1.25,;-6.31,-1.57,;-7.08,-2.9,;-8.62,-2.9,;-9.39,-4.24,;-10.93,-4.24,;-11.7,-2.9,;-13.24,-2.9,;-14.01,-4.24,;-13.24,-5.57,;-11.7,-5.57,;-15.55,-4.24,;-16.32,-2.9,;-16.32,-5.57,;-9.39,-1.57,;-8.62,-.24,;-7.08,-.24,;-6.05,.91,;-6.37,2.41,;.69,.28,;.69,-1.26,;.69,-2.8,;11.44,.43,;11.76,-1.08,)|

BDBM468528

Cn1c2CCN(C[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(-c2cccc(NC(=O)c3nc4CN(CCc4n3C)C3CCOCC3)c2Cl)c1C#N |r,wU:10.13,wD:7.6,(-6.75,1.08,;-6.43,-.43,;-7.46,-1.57,;-9,-1.57,;-9.77,-2.9,;-9,-4.24,;-9.77,-5.57,;-11.31,-5.57,;-12.08,-4.24,;-13.62,-4.24,;-14.39,-5.57,;-13.62,-6.9,;-12.08,-6.9,;-15.93,-5.57,;-16.7,-4.24,;-16.7,-6.9,;-7.46,-4.24,;-6.69,-2.9,;-5.19,-2.58,;-5.03,-1.05,;-3.69,-.28,;-3.69,1.26,;-2.36,-1.05,;-1.02,-.28,;-1.02,1.26,;.31,2.03,;1.64,1.26,;1.64,-.28,;2.98,-1.05,;2.98,-2.59,;4.31,-3.36,;5.64,-2.59,;5.64,-1.05,;6.98,-.28,;8.31,-1.05,;8.31,-2.59,;9.65,-.28,;9.81,1.25,;11.31,1.57,;12.08,2.9,;13.62,2.9,;14.39,1.57,;13.62,.24,;12.08,.24,;11.05,-.91,;11.37,-2.41,;14.39,4.24,;15.93,4.24,;16.7,5.57,;15.93,6.9,;14.39,6.9,;13.62,5.57,;4.31,-.28,;4.31,1.26,;.31,-1.05,;.31,-2.59,;.31,-4.13,)|

BDBM468529

CC(C)N(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:37.39,wD:40.46,(-17.23,-4.11,;-15.89,-3.34,;-15.89,-1.8,;-14.56,-4.11,;-14.56,-5.65,;-13.23,-3.34,;-11.89,-4.11,;-11.89,-5.65,;-10.56,-3.34,;-9.15,-3.97,;-8.12,-2.82,;-6.61,-2.5,;-6.45,-.97,;-7.86,-.35,;-8.89,-1.49,;-10.4,-1.81,;-5.12,-.2,;-5.12,1.34,;-3.79,2.11,;-2.45,1.34,;-2.45,-.2,;-3.79,-.97,;-3.79,-2.51,;-1.12,-.97,;-1.12,-2.51,;.21,-3.28,;1.55,-2.51,;1.55,-.97,;2.88,-.2,;4.22,-.97,;4.22,-2.51,;5.55,-.2,;5.71,1.33,;7.22,1.65,;7.99,2.98,;9.53,2.98,;10.3,4.32,;11.84,4.32,;12.61,5.65,;14.15,5.65,;14.92,4.32,;14.15,2.98,;12.61,2.98,;16.46,4.32,;17.23,5.65,;17.23,2.98,;10.3,1.65,;9.53,.32,;7.99,.32,;6.96,-.83,;7.28,-2.33,;.21,-.2,;.21,1.34,)|

BDBM468530

CCN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:36.38,wD:39.45,(-17.09,-4.32,;-15.76,-3.55,;-14.42,-4.32,;-14.42,-5.86,;-13.09,-3.55,;-11.76,-4.32,;-11.76,-5.86,;-10.42,-3.55,;-8.96,-4.03,;-8.05,-2.78,;-6.59,-2.3,;-6.59,-.76,;-8.05,-.29,;-8.96,-1.53,;-10.42,-2.01,;-5.26,.01,;-5.26,1.55,;-3.92,2.32,;-2.59,1.55,;-2.59,.01,;-3.92,-.76,;-3.92,-2.3,;-1.25,-.76,;-1.25,-2.3,;.08,-3.07,;1.41,-2.3,;1.41,-.76,;2.75,.01,;4.08,-.76,;4.08,-2.3,;5.41,.01,;5.58,1.54,;7.08,1.86,;7.85,3.19,;9.39,3.19,;10.16,4.53,;11.7,4.53,;12.47,5.86,;14.01,5.86,;14.78,4.53,;14.01,3.19,;12.47,3.19,;16.32,4.53,;17.09,5.86,;17.09,3.19,;10.16,1.86,;9.39,.52,;7.85,.52,;6.82,-.62,;7.59,-1.95,;.08,.01,;.08,1.55,)|

BDBM468531

CCN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wD:36.38,39.45,(-17.09,-4.32,;-15.76,-3.55,;-14.42,-4.32,;-14.42,-5.86,;-13.09,-3.55,;-11.76,-4.32,;-11.76,-5.86,;-10.42,-3.55,;-8.96,-4.03,;-8.05,-2.78,;-6.59,-2.3,;-6.59,-.76,;-8.05,-.29,;-8.96,-1.53,;-10.42,-2.01,;-5.26,.01,;-5.26,1.55,;-3.92,2.32,;-2.59,1.55,;-2.59,.01,;-3.92,-.76,;-3.92,-2.3,;-1.25,-.76,;-1.25,-2.3,;.08,-3.07,;1.41,-2.3,;1.41,-.76,;2.75,.01,;4.08,-.76,;4.08,-2.3,;5.41,.01,;5.58,1.54,;7.08,1.86,;7.85,3.19,;9.39,3.19,;10.16,4.53,;11.7,4.53,;12.47,3.19,;14.01,3.19,;14.78,4.53,;14.01,5.86,;12.47,5.86,;16.32,4.53,;17.09,5.86,;17.09,3.19,;10.16,1.86,;9.39,.52,;7.85,.52,;6.82,-.62,;7.59,-1.95,;.08,.01,;.08,1.55,)|

BDBM468532

CCN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(CCC4CCC(CC4)C(O)=O)CCc3n2C)c1Cl |(-16.71,-6.99,;-15.37,-6.22,;-14.04,-6.99,;-14.04,-8.53,;-12.71,-6.22,;-11.37,-6.99,;-11.37,-8.53,;-10.04,-6.22,;-8.57,-6.69,;-7.67,-5.45,;-6.2,-4.97,;-6.2,-3.43,;-7.67,-2.95,;-8.57,-4.2,;-10.04,-4.68,;-4.87,-2.66,;-4.87,-1.12,;-3.54,-.35,;-2.2,-1.12,;-2.2,-2.66,;-3.54,-3.43,;-3.54,-4.97,;-.87,-3.43,;-.87,-4.97,;.46,-5.74,;1.8,-4.97,;1.8,-3.43,;3.13,-2.66,;4.47,-3.43,;4.47,-4.97,;5.8,-2.66,;5.96,-1.13,;7.47,-.81,;8.24,.52,;9.78,.52,;10.55,1.86,;12.09,1.86,;12.86,3.19,;14.4,3.19,;15.17,4.53,;14.4,5.86,;12.86,5.86,;12.09,4.53,;15.17,7.19,;16.71,7.19,;14.4,8.53,;10.55,-.81,;9.78,-2.14,;8.24,-2.14,;7.21,-3.29,;7.98,-4.62,;.46,-2.66,;.46,-1.12,)|

BDBM468533

CC(C)N(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(CCC4CCC(CC4)C(O)=O)CCc3n2C)c1Cl |(-16.71,-6.99,;-15.37,-6.22,;-15.37,-4.68,;-14.04,-6.99,;-14.04,-8.53,;-12.71,-6.22,;-11.37,-6.99,;-11.37,-8.53,;-10.04,-6.22,;-8.57,-6.69,;-7.67,-5.45,;-6.2,-4.97,;-6.2,-3.43,;-7.67,-2.95,;-8.57,-4.2,;-10.04,-4.68,;-4.87,-2.66,;-4.87,-1.12,;-3.54,-.35,;-2.2,-1.12,;-2.2,-2.66,;-3.54,-3.43,;-3.54,-4.97,;-.87,-3.43,;-.87,-4.97,;.46,-5.74,;1.8,-4.97,;1.8,-3.43,;3.13,-2.66,;4.47,-3.43,;4.47,-4.97,;5.8,-2.66,;5.96,-1.13,;7.47,-.81,;8.24,.52,;9.78,.52,;10.55,1.86,;12.09,1.86,;12.86,3.19,;14.4,3.19,;15.17,4.53,;14.4,5.86,;12.86,5.86,;12.09,4.53,;15.17,7.19,;16.71,7.19,;14.4,8.53,;10.55,-.81,;9.78,-2.14,;8.24,-2.14,;7.21,-3.29,;7.98,-4.62,;.46,-2.66,;.46,-1.12,)|

BDBM468534

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4CN(Cc4o3)C(=O)CN3CC[C@@](C)(C3)C(O)=O)c1C)n2C |r|

BDBM468535

C[C@@H](CO)NCC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(C)CCc3n2C)c1Cl |r|

BDBM468536

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4CN(Cc4o3)C(=O)CN[C@@H]3C[C@H](O)C3)c1C)n2C |r,wU:36.39,38.42,(14.57,5.19,;13.8,3.86,;14.57,2.53,;13.8,1.19,;12.26,1.19,;11.49,2.53,;12.26,3.86,;9.98,2.2,;9.82,.67,;8.49,-.1,;8.49,-1.64,;7.15,.67,;5.82,-.1,;5.82,-1.64,;4.49,-2.41,;3.15,-1.64,;3.15,-.1,;4.49,.67,;4.49,2.21,;1.82,.67,;1.82,2.21,;.49,2.98,;-.85,2.21,;-.85,.67,;-2.18,-.1,;-2.18,-1.64,;-3.65,-2.11,;-4.55,-3.36,;-6.02,-2.88,;-6.02,-1.34,;-4.55,-.87,;-3.65,.38,;-7.35,-3.65,;-7.35,-5.19,;-8.68,-2.88,;-10.02,-3.65,;-11.35,-2.88,;-11.75,-1.39,;-13.24,-1.79,;-14.57,-1.02,;-12.84,-3.28,;.49,-.1,;.49,-1.64,;11.23,.05,;12,-1.29,)|

BDBM468537

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4CN(Cc4o3)C(=O)CN[C@H]3C[C@H](O)C3)c1C)n2C |r,wU:36.39,wD:38.42,(14.57,5.19,;13.8,3.86,;14.57,2.53,;13.8,1.19,;12.26,1.19,;11.49,2.53,;12.26,3.86,;9.98,2.2,;9.82,.67,;8.49,-.1,;8.49,-1.64,;7.15,.67,;5.82,-.1,;5.82,-1.64,;4.49,-2.41,;3.15,-1.64,;3.15,-.1,;4.49,.67,;4.49,2.21,;1.82,.67,;1.82,2.21,;.49,2.98,;-.85,2.21,;-.85,.67,;-2.18,-.1,;-2.18,-1.64,;-3.65,-2.11,;-4.55,-3.36,;-6.02,-2.88,;-6.02,-1.34,;-4.55,-.87,;-3.65,.38,;-7.35,-3.65,;-7.35,-5.19,;-8.68,-2.88,;-10.02,-3.65,;-11.35,-2.88,;-12.84,-3.28,;-13.24,-1.79,;-14.57,-1.02,;-11.75,-1.39,;.49,-.1,;.49,-1.64,;11.23,.05,;12,-1.29,)|

BDBM468538

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(-c3nc4CN(Cc4o3)C(=O)CN3CCC(CC3)C(O)=O)c1C)n2C

BDBM468539

CN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)c1Cl |(-15.15,-4.95,;-13.82,-5.72,;-13.82,-7.26,;-12.49,-4.95,;-11.15,-5.72,;-11.15,-7.26,;-9.82,-4.95,;-8.41,-5.58,;-7.38,-4.43,;-5.87,-4.11,;-5.71,-2.58,;-7.12,-1.95,;-8.15,-3.1,;-9.66,-3.42,;-4.38,-1.81,;-4.38,-.27,;-3.05,.5,;-1.71,-.27,;-1.71,-1.81,;-3.05,-2.58,;-3.05,-4.12,;-.38,-2.58,;-.38,-4.12,;.95,-4.89,;2.29,-4.12,;2.29,-2.58,;3.62,-1.81,;4.96,-2.58,;4.96,-4.12,;6.29,-1.81,;6.45,-.28,;7.96,.04,;8.73,1.37,;10.27,1.37,;11.04,.04,;10.27,-1.29,;8.73,-1.29,;7.7,-2.44,;8.02,-3.94,;11.04,2.71,;12.58,2.71,;13.35,4.04,;12.58,5.38,;12.58,6.92,;11.04,5.38,;10.27,4.04,;14.06,5.77,;15.15,4.68,;14.46,7.26,;.95,-1.81,;.95,-.27,)|

BDBM468540

CCN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC4CCC(CC4)C(O)=O)CCc3n2C)c1Cl |(-16.84,-6.78,;-15.51,-6.01,;-14.17,-6.78,;-14.17,-8.32,;-12.84,-6.01,;-11.51,-6.78,;-11.51,-8.32,;-10.17,-6.01,;-8.77,-6.64,;-7.74,-5.49,;-6.23,-5.17,;-6.07,-3.64,;-7.48,-3.01,;-8.51,-4.16,;-10.01,-4.48,;-4.73,-2.87,;-4.73,-1.33,;-3.4,-.56,;-2.07,-1.33,;-2.07,-2.87,;-3.4,-3.64,;-3.4,-5.18,;-.73,-3.64,;-.73,-5.18,;.6,-5.95,;1.93,-5.18,;1.93,-3.64,;3.27,-2.87,;4.6,-3.64,;4.6,-5.18,;5.93,-2.87,;6.1,-1.34,;7.6,-1.02,;8.37,.32,;9.91,.32,;10.68,1.65,;12.22,1.65,;12.99,2.98,;14.53,2.98,;15.3,4.32,;14.53,5.65,;12.99,5.65,;12.22,4.32,;15.3,6.99,;16.84,6.99,;14.53,8.32,;10.68,-1.02,;9.91,-2.35,;8.37,-2.35,;7.34,-3.5,;7.66,-5,;.6,-2.87,;.6,-1.33,)|

BDBM468541

Cn1c2CCN(CCC3CCC(CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(-c2nc3CN(Cc3o2)C(=O)CN2CC(O)C2)c1Cl |(8.25,-4.46,;7.48,-3.13,;8.51,-1.98,;10.05,-1.98,;10.82,-.65,;10.05,.68,;10.82,2.02,;12.36,2.02,;13.13,3.35,;14.67,3.35,;15.44,4.69,;14.67,6.02,;13.13,6.02,;12.36,4.69,;15.44,7.35,;16.98,7.35,;14.67,8.69,;8.51,.68,;7.74,-.65,;6.24,-.97,;6.08,-2.5,;4.74,-3.27,;4.74,-4.81,;3.41,-2.5,;2.07,-3.27,;2.07,-4.81,;.74,-5.58,;-.59,-4.81,;-.59,-3.27,;.74,-2.5,;.74,-.96,;-1.93,-2.5,;-1.93,-.96,;-3.26,-.19,;-4.59,-.96,;-4.59,-2.5,;-5.93,-3.27,;-5.93,-4.81,;-7.39,-5.29,;-8.3,-6.53,;-9.76,-6.06,;-9.76,-4.52,;-8.3,-4.04,;-7.39,-2.8,;-11.1,-6.83,;-11.1,-8.37,;-12.43,-6.06,;-13.76,-6.83,;-15.25,-6.43,;-15.65,-7.92,;-16.98,-8.69,;-14.16,-8.31,;-3.26,-3.27,;-3.26,-4.81,)|

BDBM468542

Cn1c2CCN(CCC3CCC(CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(-c2nc3CN(Cc3o2)C(=O)CN2CC[C@@H](O)C2)c1Cl |r,wD:50.56,(7.83,-3.72,;7.06,-2.38,;8.09,-1.24,;9.63,-1.24,;10.4,.1,;9.63,1.43,;10.4,2.76,;11.94,2.76,;12.71,4.1,;14.25,4.1,;15.02,5.43,;14.25,6.76,;12.71,6.76,;11.94,5.43,;15.02,8.1,;16.56,8.1,;14.25,9.43,;8.09,1.43,;7.32,.1,;5.81,-.22,;5.65,-1.76,;4.32,-2.53,;4.32,-4.07,;2.98,-1.76,;1.65,-2.53,;1.65,-4.07,;.32,-4.84,;-1.02,-4.07,;-1.02,-2.53,;.32,-1.76,;.32,-.22,;-2.35,-1.76,;-2.35,-.22,;-3.69,.55,;-5.02,-.22,;-5.02,-1.76,;-6.35,-2.53,;-6.35,-4.07,;-7.82,-4.54,;-8.72,-5.79,;-10.19,-5.31,;-10.19,-3.77,;-8.72,-3.3,;-7.82,-2.05,;-11.52,-6.08,;-11.52,-7.62,;-12.85,-5.31,;-14.19,-6.08,;-15.65,-5.61,;-16.56,-6.85,;-15.65,-8.1,;-16.42,-9.43,;-14.19,-7.62,;-3.69,-2.53,;-3.69,-4.07,)|

BDBM468543

CCN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:39.45,wD:36.38,(-17.23,-4.11,;-15.89,-3.34,;-14.56,-4.11,;-14.56,-5.65,;-13.23,-3.34,;-11.89,-4.11,;-11.89,-5.65,;-10.56,-3.34,;-9.15,-3.97,;-8.12,-2.82,;-6.61,-2.5,;-6.45,-.97,;-7.86,-.35,;-8.89,-1.49,;-10.4,-1.81,;-5.12,-.2,;-5.12,1.34,;-3.79,2.11,;-2.45,1.34,;-2.45,-.2,;-3.79,-.97,;-3.79,-2.51,;-1.12,-.97,;-1.12,-2.51,;.21,-3.28,;1.55,-2.51,;1.55,-.97,;2.88,-.2,;4.22,-.97,;4.22,-2.51,;5.55,-.2,;5.71,1.33,;7.22,1.65,;7.99,2.98,;9.53,2.98,;10.3,4.32,;11.84,4.32,;12.61,2.98,;14.15,2.98,;14.92,4.32,;14.15,5.65,;12.61,5.65,;16.46,4.32,;17.23,2.98,;17.23,5.65,;10.3,1.65,;9.53,.32,;7.99,.32,;6.96,-.83,;7.28,-2.33,;.21,-.2,;.21,1.34,)|

BDBM468544

CCN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)c1C |(-15.82,-5.72,;-14.49,-4.95,;-13.15,-5.72,;-13.15,-7.26,;-11.82,-4.95,;-10.49,-5.72,;-10.49,-7.26,;-9.15,-4.95,;-7.74,-5.58,;-6.71,-4.43,;-5.21,-4.11,;-5.05,-2.58,;-6.45,-1.95,;-7.48,-3.1,;-8.99,-3.42,;-3.71,-1.81,;-3.71,-.27,;-2.38,.5,;-1.05,-.27,;-1.05,-1.81,;-2.38,-2.58,;-2.38,-4.12,;.29,-2.58,;.29,-4.12,;1.62,-4.89,;2.96,-4.12,;2.96,-2.58,;4.29,-1.81,;5.62,-2.58,;5.62,-4.12,;6.96,-1.81,;7.12,-.28,;8.62,.04,;9.39,1.37,;10.93,1.37,;11.7,.04,;10.93,-1.29,;9.39,-1.29,;8.36,-2.44,;8.68,-3.94,;11.7,2.71,;13.24,2.71,;14.01,4.04,;13.24,5.38,;12.84,6.86,;11.7,5.38,;10.93,4.04,;14.73,5.77,;15.82,4.68,;15.13,7.26,;1.62,-1.81,;1.62,-.27,)|

BDBM468545

CCN(C)CCC(=O)N1Cc2nc(oc2C1)-c1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(C)(CC2)C(O)=O)c1Cl |(-16.49,-4.95,;-15.15,-5.72,;-13.82,-4.95,;-13.82,-3.41,;-12.49,-5.72,;-11.15,-4.95,;-9.82,-5.72,;-9.82,-7.26,;-8.48,-4.95,;-7.08,-5.58,;-6.05,-4.43,;-4.54,-4.11,;-4.38,-2.58,;-5.79,-1.95,;-6.82,-3.1,;-8.32,-3.42,;-3.05,-1.81,;-3.05,-.27,;-1.71,.5,;-.38,-.27,;-.38,-1.81,;-1.71,-2.58,;-1.71,-4.12,;.95,-2.58,;.95,-4.12,;2.29,-4.89,;3.62,-4.12,;3.62,-2.58,;4.96,-1.81,;6.29,-2.58,;6.29,-4.12,;7.62,-1.81,;7.78,-.28,;9.29,.04,;10.06,1.37,;11.6,1.37,;12.37,.04,;11.6,-1.29,;10.06,-1.29,;9.03,-2.44,;9.35,-3.94,;12.37,2.71,;13.91,2.71,;14.68,4.04,;13.91,5.38,;13.51,6.86,;12.37,5.38,;11.6,4.04,;15.4,5.77,;16.49,4.68,;15.8,7.26,;2.29,-1.81,;2.29,-.27,)|

BDBM468546

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3C4C[C@H]5CC3CC(C5)(C4)C(O)=O)c1C)n2C |r,wD:40.50,TLB:47:44:37:39.40.41,THB:31:37:44.43.46:39.40.41,45:44:37:39.40.41,45:40:37:44.43.46,47:44:39:37.42.41,(15.16,7.01,;14.39,5.68,;15.16,4.34,;14.39,3.01,;12.85,3.01,;12.08,4.34,;12.85,5.68,;10.58,4.02,;10.42,2.49,;9.08,1.72,;9.08,.18,;7.75,2.49,;6.42,1.72,;6.42,.18,;5.08,-.59,;3.75,.18,;3.75,1.72,;5.08,2.49,;5.08,4.03,;2.41,2.49,;2.41,4.03,;1.08,4.8,;-.25,4.03,;-.25,2.49,;-1.59,1.72,;-2.92,2.49,;-2.92,4.03,;-4.25,1.72,;-4.41,.19,;-5.92,-.13,;-6.69,-1.47,;-8.23,-1.47,;-9,-.13,;-8.23,1.2,;-6.69,1.2,;-5.66,2.35,;-5.98,3.85,;-9,-2.8,;-9.84,-4.7,;-9.84,-6.24,;-11.17,-7.01,;-10.41,-5.84,;-10.4,-3.44,;-11.6,-2.77,;-12.5,-4.7,;-12.5,-6.24,;-11.17,-3.93,;-13.83,-3.93,;-15.16,-4.7,;-13.83,-2.39,;1.08,1.72,;1.08,.18,;11.82,1.86,;12.14,.36,)|

BDBM468547

CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCc4n3C)C3C4C[C@H]5CC3CC(C5)(C4)C(O)=O)c1C)n2C |r,wU:40.50,TLB:47:44:41:37.38.39,47:44:37:41.40.39,THB:31:37:44.46.43:41.40.39,45:44:37:41.40.39,45:40:37:44.46.43,(15.16,7.01,;14.39,5.68,;15.16,4.34,;14.39,3.01,;12.85,3.01,;12.08,4.34,;12.85,5.68,;10.58,4.02,;10.42,2.49,;9.08,1.72,;9.08,.18,;7.75,2.49,;6.42,1.72,;6.42,.18,;5.08,-.59,;3.75,.18,;3.75,1.72,;5.08,2.49,;5.08,4.03,;2.41,2.49,;2.41,4.03,;1.08,4.8,;-.25,4.03,;-.25,2.49,;-1.59,1.72,;-2.92,2.49,;-2.92,4.03,;-4.25,1.72,;-4.41,.19,;-5.92,-.13,;-6.69,-1.47,;-8.23,-1.47,;-9,-.13,;-8.23,1.2,;-6.69,1.2,;-5.66,2.35,;-5.98,3.85,;-9,-2.8,;-10.4,-3.44,;-10.41,-5.84,;-11.17,-7.01,;-9.84,-6.24,;-9.84,-4.7,;-11.17,-3.93,;-12.5,-4.7,;-12.5,-6.24,;-11.6,-2.77,;-13.83,-3.93,;-15.16,-4.7,;-13.83,-2.39,;1.08,1.72,;1.08,.18,;11.82,1.86,;12.14,.36,)|

BDBM468548

CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM468549

CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

BDBM468550

Cn1c2CCN(CC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC2)c1Cl

BDBM468551

Cn1c2CCN(CC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl

BDBM468552

Cn1c2CCN(CCO)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM468553

C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C |r|

BDBM468554

C[C@@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C |r|

BDBM468555

Cn1c2CCN(C[C@@]34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |r,wU:7.6,(-6.75,.41,;-6.43,-1.09,;-7.46,-2.24,;-9,-2.24,;-9.77,-3.57,;-9,-4.9,;-9.77,-6.24,;-11.31,-6.24,;-12.08,-4.9,;-13.62,-4.9,;-14.39,-6.24,;-13.62,-7.57,;-12.08,-7.57,;-12.91,-5.84,;-15.93,-6.24,;-16.7,-4.9,;-16.7,-7.57,;-7.46,-4.9,;-6.69,-3.57,;-5.19,-3.25,;-5.03,-1.72,;-3.69,-.95,;-3.69,.59,;-2.36,-1.72,;-1.02,-.95,;-1.02,.59,;.31,1.36,;1.64,.59,;1.64,-.95,;.31,-1.72,;.31,-3.26,;2.98,-1.72,;2.98,-3.26,;4.31,-4.03,;5.64,-3.26,;5.64,-1.72,;6.98,-.95,;8.31,-1.72,;8.31,-3.26,;9.65,-.95,;9.81,.58,;11.31,.9,;12.08,2.24,;13.62,2.24,;14.39,.9,;13.62,-.43,;12.08,-.43,;11.05,-1.58,;11.37,-3.08,;14.39,3.57,;15.93,3.57,;16.7,4.9,;15.93,6.24,;16.7,7.57,;14.39,6.24,;13.62,4.9,;4.31,-.95,;4.31,.59,)|

BDBM468556

Cn1c2CCN(C[C@@]34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |r,wD:7.6,(-6.75,.41,;-6.43,-1.09,;-7.46,-2.24,;-9,-2.24,;-9.77,-3.57,;-9,-4.9,;-9.77,-6.24,;-11.31,-6.24,;-12.08,-7.57,;-13.62,-7.57,;-14.39,-6.24,;-13.62,-4.9,;-12.08,-4.9,;-12.91,-5.84,;-15.93,-6.24,;-16.7,-4.9,;-16.7,-7.57,;-7.46,-4.9,;-6.69,-3.57,;-5.19,-3.25,;-5.03,-1.72,;-3.69,-.95,;-3.69,.59,;-2.36,-1.72,;-1.02,-.95,;-1.02,.59,;.31,1.36,;1.64,.59,;1.64,-.95,;.31,-1.72,;.31,-3.26,;2.98,-1.72,;2.98,-3.26,;4.31,-4.03,;5.64,-3.26,;5.64,-1.72,;6.98,-.95,;8.31,-1.72,;8.31,-3.26,;9.65,-.95,;9.81,.58,;11.31,.9,;12.08,2.24,;13.62,2.24,;14.39,.9,;13.62,-.43,;12.08,-.43,;11.05,-1.58,;11.37,-3.08,;14.39,3.57,;15.93,3.57,;16.7,4.9,;15.93,6.24,;16.7,7.57,;14.39,6.24,;13.62,4.9,;4.31,-.95,;4.31,.59,)|

BDBM481589

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C(N)=O)c1Cl

BDBM481590

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)S(N)(=O)=O)c1Cl

BDBM481603

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC(C)(C)CC(O)=O)CCc3n2C)c1Cl

BDBM481642

Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |(-7.14,3.08,;-6.82,1.58,;-7.85,.43,;-9.39,.43,;-10.16,-.9,;-9.39,-2.24,;-10.16,-3.57,;-11.7,-3.57,;-12.47,-4.9,;-14.01,-4.9,;-14.78,-6.24,;-14.01,-7.57,;-12.47,-7.57,;-11.7,-6.24,;-13.56,-5.99,;-14.78,-8.91,;-16.32,-8.91,;-14.01,-10.24,;-7.85,-2.24,;-7.08,-.9,;-5.57,-.58,;-5.41,.95,;-4.08,1.72,;-4.08,3.26,;-2.74,.95,;-1.41,1.72,;-1.41,3.26,;-.08,4.03,;1.26,3.26,;1.26,1.72,;-.08,.95,;-.08,-.59,;2.59,.95,;2.59,-.59,;3.93,-1.36,;5.26,-.59,;5.26,.95,;6.59,1.72,;7.93,.95,;7.93,-.59,;9.26,1.72,;9.42,3.25,;10.93,3.57,;11.7,4.9,;13.24,4.9,;14.01,3.57,;13.24,2.24,;11.7,2.24,;10.67,1.09,;10.99,-.41,;14.01,6.24,;15.55,6.24,;16.32,7.57,;15.55,8.91,;16.32,10.24,;14.01,8.91,;13.24,7.57,;3.93,1.72,;3.93,3.26,)|

BDBM518543

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)(F)F)cccc1-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM518544

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)(F)F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM518545

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)(F)F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM518558

Cc1cc2cc(CN3CC[C@@H](O)C3)cnc2c(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c2C)n1 |r|

BDBM555104

CN1CCc2c(C1)cc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c1C)n2C |r|

BDBM555105

Cc1c(cccc1-c1cccc(Cc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM555106

Cc1c(cccc1-c1cccc(Cc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1 |r|

BDBM555107

Cc1c(cccc1-c1cccc(Cc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM555108

Cc1c(cccc1-c1cccc(Cc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1 |r|

BDBM555109

Cc1c(Cc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC(C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM555144

CC(C)N1CCc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CNCCCCO)cc(C#N)c3o2)c1C

BDBM555176

Cc1c(Nc2nccn3c(CC4CC[C@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r|

BDBM555190

Cc1c(Nc2nccc3cc(ccc23)C2=NCCN2)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r,t:16|

BDBM555204

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNC4C[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r,wU:39.45,wD:15.15,(-3.12,-2.58,;-3.12,-1.04,;-4.46,-.27,;-5.79,-1.04,;-7.12,-.27,;-7.12,1.27,;-8.46,2.04,;-9.79,1.27,;-9.79,-.27,;-11.12,-1.04,;-11.12,-2.58,;-12.46,-3.35,;-13.79,-2.58,;-13.95,-1.05,;-15.46,-.73,;-16.23,-2.06,;-17.72,-2.46,;-15.2,-3.21,;-9.79,-3.35,;-8.46,-2.58,;-8.46,-1.04,;-4.46,1.27,;-3.12,2.04,;-1.79,1.27,;-1.79,-.27,;-.45,-1.04,;-.45,-2.58,;.88,-3.35,;2.21,-2.58,;2.21,-1.04,;3.55,-.27,;3.55,1.27,;6.21,1.27,;7.55,2.04,;8.88,1.27,;10.21,2.04,;11.55,1.27,;13.04,1.67,;14.37,.9,;15.14,2.23,;13.81,3,;16.63,2.63,;17.72,1.54,;17.02,4.12,;8.88,-.27,;7.55,-1.04,;7.55,-2.58,;7.55,-4.12,;6.21,-.27,;4.88,-1.04,;.88,-.27,;.88,1.27,)|

BDBM555205

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNC4C[C@@H](C4)C(O)=O)cc(C#N)c3o2)c1C |r,wD:15.15,39.45,(-3.12,-2.58,;-3.12,-1.04,;-4.46,-.27,;-5.79,-1.04,;-7.12,-.27,;-7.12,1.27,;-8.46,2.04,;-9.79,1.27,;-9.79,-.27,;-11.12,-1.04,;-11.12,-2.58,;-12.46,-3.35,;-13.79,-2.58,;-13.95,-1.05,;-15.46,-.73,;-16.23,-2.06,;-17.72,-2.46,;-15.2,-3.21,;-9.79,-3.35,;-8.46,-2.58,;-8.46,-1.04,;-4.46,1.27,;-3.12,2.04,;-1.79,1.27,;-1.79,-.27,;-.45,-1.04,;-.45,-2.58,;.88,-3.35,;2.21,-2.58,;2.21,-1.04,;3.55,-.27,;3.55,1.27,;6.21,1.27,;7.55,2.04,;8.88,1.27,;10.22,2.04,;11.55,1.27,;13.04,1.67,;13.81,3,;15.14,2.23,;14.37,.9,;16.63,2.63,;17.72,1.54,;17.03,4.12,;8.88,-.27,;7.55,-1.04,;7.55,-2.58,;7.55,-4.12,;6.21,-.27,;4.88,-1.04,;.88,-.27,;.88,1.27,)|

BDBM562407

Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl |r|

BDBM562408

Cc1c(Nc2nc(nc3cc(CN4CC[C@@](C)(O)C4)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl |r|

BDBM562409

Cc1c(Nc2nc(nc3cc(CN[C@@H]4CCC[C@@H]4O)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl |r|

BDBM562410

Cc1c(Nc2nc(nc3cc(CN4CC[C@H](O)C4)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl |r|

BDBM562411

Cc1c(Nc2nc(nc3cc(CN4CC[C@](C)(O)C4)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl |r|

BDBM562412

Cc1c(Nc2nc(nc3cc(CN4CCCC4)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM562413

Cc1c(Nc2nc(nc3cc(CN4CC(C)(O)C4)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM562414

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)F)c1C |r|

BDBM562415

C[C@@H]1CCCN1Cc1cnc2c(Nc3cccc(c3C)-c3cccc(NC(=O)c4nc5CN(CCC67CCC(CC6)(C7)C(O)=O)CCc5n4C)c3Cl)nc(nc2c1)C(F)F |r|

BDBM562416

C[C@H]1C[C@@H](O)CN1Cc1cnc2c(Nc3cccc(c3C)-c3cccc(NC(=O)c4nc5CN(CCC67CCC(CC6)(C7)C(O)=O)CCc5n4C)c3Cl)nc(nc2c1)C(F)F |r|

BDBM562417

C[C@@H]1C[C@@H](O)CN1Cc1cnc2c(Nc3cccc(c3C)-c3cccc(NC(=O)c4nc5CN(CCC67CCC(CC6)(C7)C(O)=O)CCc5n4C)c3Cl)nc(nc2c1)C(F)F |r|

BDBM562418

Cc1c(Nc2nc(nc3cc(CN4CC(O)C4)cnc23)C(F)F)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

BDBM562419

C[C@@H]1C[C@H](O)CN1Cc1cnc2c(Nc3cccc(c3C)-c3cccc(NC(=O)c4nc5CN(CCC67CCC(CC6)(C7)C(O)=O)CCc5n4C)c3Cl)nc(nc2c1)C(F)F |r|

BDBM562420

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(Nc2nc(nc3cc(CN4CC[C@H](O)C4)cnc23)C(F)F)c1C |r|

BDBM562421

Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(Nc2nc(nc3cc(CN4CC[C@](C)(O)C4)cnc23)C(F)F)c1C |r|

BDBM562422

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:42.49,wD:39.42,15.15,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-12.02,-4.85,;-13.56,-4.85,;-14.33,-6.18,;-13.56,-7.52,;-12.02,-7.52,;-15.87,-6.18,;-16.64,-4.85,;-16.64,-7.52,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562423

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wD:39.42,42.49,15.15,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-12.02,-4.85,;-13.56,-4.85,;-14.33,-6.18,;-13.56,-7.52,;-12.02,-7.52,;-15.87,-6.18,;-16.64,-4.85,;-16.64,-7.52,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562424

Cc1c(Nc2nccc3cc(CN4CCCC4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wD:38.41,41.48,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-12.02,-4.85,;-13.56,-4.85,;-14.33,-6.18,;-13.56,-7.52,;-12.02,-7.52,;-15.87,-6.18,;-16.64,-4.85,;-16.64,-7.52,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562425

Cc1c(Nc2nccc3cc(CN[C@H]4CCC[C@@H]4O)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:43.50,13.12,wD:40.43,17.18,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;16.45,1.27,;16.77,2.78,;18.31,2.94,;18.93,1.53,;17.79,.5,;17.95,-1.03,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-12.02,-4.85,;-13.56,-4.85,;-14.33,-6.18,;-13.56,-7.52,;-12.02,-7.52,;-15.87,-6.18,;-16.64,-4.85,;-16.64,-7.52,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562426

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:43.50,wD:40.43,15.15,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-11.87,-7.59,;-13.41,-7.75,;-14.03,-9.16,;-13.13,-10.4,;-11.59,-10.24,;-10.97,-8.84,;-13.75,-11.81,;-15.28,-11.97,;-12.85,-13.06,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562427

Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wD:40.43,43.50,15.15,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-11.87,-7.59,;-13.41,-7.75,;-14.03,-9.16,;-13.13,-10.4,;-11.59,-10.24,;-10.97,-8.84,;-13.75,-11.81,;-15.28,-11.97,;-12.85,-13.06,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562428

Cc1c(Nc2nccc3cc(CN4CC[C@H](O)C4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:15.15,wD:39.42,42.49,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-12.02,-4.85,;-13.56,-4.85,;-14.33,-6.18,;-13.56,-7.52,;-12.02,-7.52,;-15.87,-6.18,;-16.64,-4.85,;-16.64,-7.52,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562429

Cc1c(Nc2nccc3cc(CN4CC[C@](C)(O)C4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:15.16,wD:40.43,43.50,15.15,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;17.64,1.66,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-12.02,-4.85,;-13.56,-4.85,;-14.33,-6.18,;-13.56,-7.52,;-12.02,-7.52,;-15.87,-6.18,;-16.64,-4.85,;-16.64,-7.52,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562430

Cc1c(Nc2nccc3cc(CN4CC[C@@](C)(O)C4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:44.51,15.15,wD:41.44,15.16,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;17.48,1.67,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-11.87,-7.59,;-13.41,-7.75,;-14.03,-9.16,;-13.13,-10.4,;-11.59,-10.24,;-10.97,-8.84,;-13.75,-11.81,;-15.28,-11.97,;-12.85,-13.06,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562431

Cc1c(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)ccc23)c1C |r,wU:16.19,wD:13.12,48.52,(.37,-3.21,;.37,-1.67,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-11.87,-7.59,;-13.41,-7.75,;-14.03,-9.16,;-13.13,-10.4,;-11.59,-10.24,;-10.97,-8.84,;-13.75,-11.81,;-15.28,-11.97,;-12.85,-13.06,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;-.96,.65,;.37,1.42,;1.71,.65,;1.71,-.9,;3.04,-1.67,;3.04,-3.21,;4.38,-3.98,;5.71,-3.21,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;4.38,-.9,;4.38,.64,)|

BDBM562432

Cn1c2CCN(CC[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)ccc23)c1Cl |r,wU:11.14,wD:8.7,48.52,(-6.69,.47,;-6.37,-1.04,;-7.4,-2.18,;-8.94,-2.18,;-9.71,-3.52,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-11.87,-7.59,;-13.41,-7.75,;-14.03,-9.16,;-13.13,-10.4,;-11.59,-10.24,;-10.97,-8.84,;-13.75,-11.81,;-15.28,-11.97,;-12.85,-13.06,;-7.4,-4.85,;-6.63,-3.52,;-5.12,-3.2,;-4.96,-1.67,;-3.63,-.9,;-3.63,.64,;-2.29,-1.67,;-.96,-.9,;-.96,.65,;.37,1.42,;1.71,.65,;1.71,-.9,;.37,-1.67,;.37,-3.21,;3.04,-1.67,;3.04,-3.21,;4.38,-3.98,;5.71,-3.21,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;4.38,-.9,;4.38,.64,)|

BDBM562433

Cc1c(NC(=O)c2nc3CN(CC[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)cccc1-c1cccc(Nc2nccc3cc(CN4CC[C@@H](O)C4)ccc23)c1Cl |r,wU:16.19,wD:13.12,48.52,(.37,-3.21,;.37,-1.67,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-11.87,-7.59,;-13.41,-7.75,;-14.03,-9.16,;-13.13,-10.4,;-11.59,-10.24,;-10.97,-8.84,;-13.75,-11.81,;-15.28,-11.97,;-12.85,-13.06,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;-.96,.65,;.37,1.42,;1.71,.65,;1.71,-.9,;3.04,-1.67,;3.04,-3.21,;4.38,-3.98,;5.71,-3.21,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;4.38,-.9,;4.38,.64,)|

BDBM562434

Cc1c(Nc2ncnc3cc(CN4CC[C@H](O)C4)ccc23)cccc1-c1cccc(NC(=O)c2nc3CN(C[C@H]4CC[C@@H](CC4)C(O)=O)CCc3n2C)c1Cl |r,wU:42.49,15.15,wD:39.42,(4.38,.64,;4.38,-.9,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-3.98,;11.04,-3.21,;11.04,-1.67,;12.38,-.9,;12.38,.64,;13.71,1.41,;15.05,.64,;15.21,-.89,;16.71,-1.21,;17.48,.13,;19.01,.29,;16.45,1.27,;11.05,1.41,;9.71,.64,;9.71,-.9,;5.71,-3.21,;4.38,-3.98,;3.04,-3.21,;3.04,-1.67,;1.71,-.9,;1.71,.65,;.37,1.42,;-.96,.65,;-.96,-.9,;-2.29,-1.67,;-3.63,-.9,;-3.63,.64,;-4.96,-1.67,;-5.12,-3.2,;-6.63,-3.52,;-7.4,-4.85,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-12.02,-4.85,;-13.56,-4.85,;-14.33,-6.18,;-13.56,-7.52,;-12.02,-7.52,;-15.87,-6.18,;-16.64,-4.85,;-16.64,-7.52,;-9.71,-3.52,;-8.94,-2.18,;-7.4,-2.18,;-6.37,-1.04,;-6.69,.47,;.37,-1.67,;.37,-3.21,)|

BDBM562445

Cn1c2CCN(CC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCC(O)CC2)c1Cl |(-6.69,.47,;-6.37,-1.04,;-7.4,-2.18,;-8.94,-2.18,;-9.71,-3.52,;-8.94,-4.85,;-9.71,-6.18,;-11.25,-6.18,;-12.02,-4.85,;-13.56,-4.85,;-14.33,-6.18,;-13.56,-7.52,;-12.02,-7.52,;-12.92,-5.56,;-15.87,-6.18,;-16.64,-4.85,;-16.64,-7.52,;-7.4,-4.85,;-6.63,-3.52,;-5.12,-3.2,;-4.96,-1.67,;-3.63,-.9,;-3.63,.64,;-2.29,-1.67,;-.96,-.9,;-.96,.65,;.37,1.42,;1.71,.65,;1.71,-.9,;.37,-1.67,;.37,-3.21,;3.04,-1.67,;3.04,-3.21,;4.38,-3.98,;5.71,-3.21,;5.71,-1.67,;7.04,-.9,;8.38,-1.67,;8.38,-3.21,;9.71,-.9,;9.87,.64,;11.38,.96,;12.15,2.29,;13.69,2.29,;14.46,.96,;13.69,-.38,;12.15,-.38,;11.12,-1.52,;11.44,-3.03,;14.46,3.62,;16,3.62,;16.77,4.96,;16,6.29,;16.77,7.62,;14.46,6.29,;13.69,4.96,;4.38,-.9,;4.38,.64,)|

BDBM563299

Cc1c(cccc1-c1ccccc1)-c1cn2cc(CNCCO)ccc2n1

BDBM563300

Cc1c(cccc1-c1ccccc1)-c1cc2cc(CNCCO)ccn2c1

BDBM563301

Cc1c(cccc1-c1ccccc1)-c1cc2cc(CN3CCCC[C@H]3C(O)=O)ccn2c1 |r|

BDBM563302

Cc1c(cccc1-c1ccccc1)-c1cc2cc(CN3CCCC[C@H]3C(O)=O)ncn2c1 |r|

BDBM50540066

Cc1c(cccc1-c1ccccc1)-c1cn2nc(CNCCO)cnc2n1

BDBM563304

Cc1c(cccc1-c1ccccc1)-c1cn2nc(CNCC#N)cnc2n1

BDBM563305

Cc1c(cccc1-c1ccccc1)-c1cn2nc(CNCC(N)=O)cnc2n1

BDBM563306

CN(CCO)Cc1cnc2nc(cn2n1)-c1cccc(-c2ccccc2)c1C

BDBM563307

Cc1cc(CNCCO)cn2cc(nc12)-c1cccc(c1C)-c1ccccc1

BDBM563308

Cc1cc(CN2CCCC[C@H]2C(O)=O)cn2cc(nc12)-c1cccc(c1C)-c1ccccc1 |r|

BDBM563309

Cc1c(cccc1-c1ccccc1)-c1cn2cc(CNCCO)cc(Cl)c2n1

BDBM563310

Cc1c(cccc1-c1ccccc1)-c1cn2cc(CNCCO)cnc2n1

BDBM563311

Cc1c(cccc1-c1ccccc1)-c1cn2cc(CNCCO)ncc2n1

BDBM563312

Cc1c(cccc1-c1ccccc1)-c1cn2nc(CN3CCCC[C@H]3C(O)=O)ccc2n1 |r|

BDBM563313

Cc1c(cccc1-c1ccccc1)-c1cn2nc(CNCCO)ccc2n1

BDBM563314

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)ccn2n1

BDBM563315

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)ccn2n1 |r|

BDBM563316

Cc1c(cccc1-c1ccccc1)-c1nc2ccc(CNCCO)cn2n1

BDBM563317

Cc1c(cccc1-c1ccccc1)-c1nc2ccc(CN3CCCC[C@H]3C(O)=O)cn2n1 |r|

BDBM563318

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)nc(C)n2n1

BDBM563319

Cc1c(cccc1-c1ccccc1)-c1nc2c(Cl)cc(CNCCO)cn2n1

BDBM563320

COCCNc1cc(CNCCO)cn2nc(nc12)-c1cccc(c1C)-c1ccccc1

BDBM563321

Cc1c(cccc1-c1ccccc1)-c1nc2c(CCCC#N)cc(CNCCO)cn2n1

BDBM563322

Cc1c(cccc1-c1ccccc1)-c1nc2c(CC#N)cc(CNCCO)cn2n1

BDBM563323

OCCNCc1cc(Cl)c2nc(nn2c1)-c1cccc(-c2ccc3OCCOc3c2)c1C#N

BDBM563324

OCCNCc1cc(C#N)c2nc(nn2c1)-c1cccc(-c2ccc3OCCOc3c2)c1C#N

BDBM563325

OCCNCc1cc(CC#N)c2nc(nn2c1)-c1cccc(-c2ccc3OCCOc3c2)c1C#N

BDBM50542976

Cc1c(Nc2cccc3cc(CNCCO)cnc23)cccc1-c1ccccc1

BDBM587720

Cc1c(Nc2nccc3cc(CNCCO)cnc23)cccc1-c1ccccc1

BDBM587721

Cc1c(Nc2nccc3cc(CN4CCCCC4C(O)=O)cnc23)cccc1-c1ccccc1

BDBM587722

Cc1c(Nc2ncnc3cc(CN4CCCCC4C(O)=O)cnc23)cccc1-c1ccccc1

BDBM587723

Cc1c(Nc2nccc3c(CN4CCCCC4C(O)=O)ccnc23)cccc1-c1ccccc1

BDBM587724

Cc1c(Nc2nccc3c(CNCCO)ccnc23)cccc1-c1ccccc1

BDBM587725

Cc1c(Nc2cccc3c(CNCCO)ccnc23)cccc1-c1ccccc1

BDBM587726

Cc1c(Nc2cccc3c(CN4CCCCC4C(O)=O)ccnc23)cccc1-c1ccccc1

BDBM587727

Cc1c(Nc2nccc3c(Cl)c(CNCCO)cnc23)cccc1-c1ccccc1

BDBM587728

COc1c(CNCCO)cnc2c(Nc3cccc(c3C)-c3ccccc3)nccc12

BDBM587729

Cc1c(Nc2nccc3c(Cl)c(CN4CCCCC4C(O)=O)cnc23)cccc1-c1ccccc1

BDBM587730

Cc1c(Nc2nccc3c(CNCCO)ccnc23)cccc1-c1ccc2OCCOc2c1

BDBM587731

Cc1c(Nc2nccc3c(CN4CCCCC4C(O)=O)ccnc23)cccc1-c1ccc2OCCOc2c1

BDBM587732

Cc1c(Nc2nccc3nc(CNCCO)cnc23)cccc1-c1ccccc1

BDBM587734

Cc1c(Nc2nccc3nc(CN4CCCC[C@H]4C(O)=O)cnc23)cccc1-c1ccccc1 |r|

BDBM587735

OCCNCc1cnc2c(Nc3cccc(-c4ccc5OCCOc5c4)c3C#N)nccc2c1

BDBM587736

Cc1c(Nc2nccc3cc(CNCCO)cnc23)cccc1-c1ccc2OCCOc2c1

BDBM587737

Cc1c(Nc2nccc3cc(CNCCO)cnc23)cccc1C1=CCCCC1 |t:26|

BDBM587738

OCCNCc1cnc2c(Nc3cccc(-c4ccccc4)c3C#N)nccc2c1

BDBM587739

OCCNCc1cnc2c(Nc3cccc(C4=CCCCC4)c3C#N)nccc2c1 |t:16|

BDBM587740

OCCNCc1cnc2c(Nc3cccc(C4CCCCC4)c3C#N)nccc2c1

BDBM592296

Cc1c(cccc1-c1ccccc1)-c1cc2ccc(CNCCO)nc2o1

BDBM592297

Cc1c(cccc1-c1ccccc1)-c1cc2ccc(CN3CCCC[C@H]3C(O)=O)nc2o1 |r|

BDBM592298

Cc1cc(CNCCO)nc2cc(oc12)-c1cccc(c1C)-c1ccccc1

BDBM592299

Cc1cc(CN2CCCC[C@H]2C(O)=O)nc2cc(oc12)-c1cccc(c1C)-c1ccccc1 |r|

BDBM592300

Cc1nc(CNCCO)cc2cc(oc12)-c1cccc(c1C)-c1ccccc1

BDBM592301

Cc1nc(CN2CCCC[C@H]2C(O)=O)cc2cc(oc12)-c1cccc(c1C)-c1ccccc1 |r|

BDBM592302

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)ccc2o1 |r|

BDBM50540069

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)ccc2o1

BDBM592304

Cc1c(cccc1-c1ccccc1)-c1cc2cc(CN3CCCC[C@H]3C(O)=O)cnc2o1 |r|

BDBM592305

Cc1c(cccc1-c1ccccc1)-c1cc2cc(CNCCO)cnc2o1

BDBM592306

Cc1cc(CN2CCCC[C@H]2C(O)=O)cc2nc(oc12)-c1cccc(-c2ccccc2)c1C |r|

BDBM592307

Cc1cc(CNCCO)cc2nc(oc12)-c1cccc(c1C)-c1ccccc1

BDBM592308

Cc1cc(CN2CCCC[C@H]2C(O)=O)cc2nc(oc12)-c1cccc(-c2ccccc2)c1C#N |r|

BDBM592309

Cc1cc(CNCCO)cc2nc(oc12)-c1cccc(-c2ccccc2)c1C#N

BDBM592310

Cc1cc(CN2CCCC[C@H]2C(O)=O)cc2nc(oc12)-c1cccc(c1C)-c1ccc2OCCOc2c1 |r|

BDBM592311

Cc1cc(CNCCO)cc2nc(oc12)-c1cccc(c1C)-c1ccc2OCCOc2c1

BDBM592312

Cc1cc(CN2CCCC[C@H]2C(O)=O)cc2nc(oc12)-c1cccc(-c2ccc3OCCOc3c2)c1C#N |r|

BDBM592313

Cc1cc(CNCCO)cc2nc(oc12)-c1cccc(-c2ccc3OCCOc3c2)c1C#N

BDBM592314

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)ccc2s1 |r|

BDBM592315

Cc1c(cccc1-c1ccccc1)-c1cc2nc(CN3CCCC[C@H]3C(O)=O)ccc2o1 |r|

BDBM592316

Cc1c(cccc1-c1ccccc1)-c1cc2nc(CNCCO)ccc2o1

BDBM592317

Cc1cc(CN2CCCC[C@H]2C(O)=O)cc2sc(nc12)-c1cccc(-c2ccccc2)c1C |r|

BDBM592318

Cc1cc(CNCCO)cc2sc(nc12)-c1cccc(c1C)-c1ccccc1

BDBM592319

Cc1c(cccc1-c1ccccc1)-c1cc2nc(CNCCO)cnc2o1

BDBM592320

Cc1c(cccc1-c1ccccc1)-c1cc2nc(CN3CCCC[C@H]3C(O)=O)cnc2o1 |r|

BDBM592321

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)c(OCC#N)cc2o1 |r|

BDBM592322

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)c(OCC#N)cc2o1

BDBM592323

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)c(OCCCC#N)cc2o1 |r|

BDBM592324

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)c(OCc3cccc(c3)C#N)cc2o1

BDBM592325

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)c(OCc3ccccn3)cc2o1

BDBM592326

COc1cc2oc(nc2cc1CNCCO)-c1cccc(c1C)-c1ccccc1

BDBM592327

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)c(OCCN3CCOCC3)cc2o1

BDBM592328

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)ncc2o1

BDBM592329

Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)c(OCCCC#N)c(C)c2o1

BDBM592330

Cc1c(ccnc1-c1nc2cc(CN3CCCC[C@H]3C(O)=O)c(OCC#N)cc2o1)-c1ccc2OCCOc2c1 |r|

BDBM592331

Cc1c(cccc1-c1ccc2OCCOc2c1)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)c(OCC#N)cc2o1 |r|

BDBM592332

OC(=O)[C@@H]1CCCCN1Cc1cc2nc(oc2cc1OCC#N)-c1cccc(-c2ccc3OCCOc3c2)c1C#N |r|

BDBM592333

Cc1c(cccc1-c1ccccc1)-c1nc2ccc(CN3CCCC[C@H]3C(O)=O)cc2o1 |r|

BDBM592334

Cc1c(cccc1-c1ccccc1F)-c1nc2cc(CNCCO)c(OCC#N)cc2o1

BDBM592335

Cc1c(cccc1C1=CCCCC1)-c1nc2cc(CNCCO)c(OCC#N)cc2o1 |t:8|

BDBM597787

Cc1c(cccc1-c1ccccc1)-c1nc2CNCCc2s1

BDBM50540067

Cc1c(cccc1-c1ccccc1)-c1nc2CCNCc2s1

BDBM597801

CN1CCc2nc(sc2C1)-c1cccc(-c2ccccc2)c1C

BDBM597804

Cc1c(cccc1-c1ccccc1)-c1nc2CCN(CCO)Cc2s1

BDBM597824

C[C@H](O)CN1CCc2nc(sc2C1)-c1cccc(-c2ccccc2)c1C |r|

BDBM597825

Cc1c(cccc1-c1ccccc1)-c1nc2CCN(Cc2s1)C1CCOCC1

BDBM597826

Cc1c(cccc1-c1ccccc1)-c1nc2CCN(Cc2s1)C1CCC(CC1)C(O)=O |(-4.51,1.49,;-4.51,-.05,;-3.17,-.82,;-3.17,-2.36,;-4.51,-3.13,;-5.84,-2.36,;-5.84,-.82,;-7.17,-.05,;-7.17,1.49,;-8.51,2.26,;-9.84,1.49,;-9.84,-.05,;-8.51,-.82,;-1.84,-.05,;-1.68,1.48,;-.17,1.8,;.6,3.13,;2.14,3.13,;2.91,1.8,;2.14,.47,;.6,.47,;-.43,-.68,;4.45,1.8,;5.22,.47,;6.76,.47,;7.53,1.8,;6.76,3.13,;5.22,3.13,;9.07,1.8,;9.84,.47,;9.84,3.13,)|

BDBM597827

Cc1c(cccc1-c1ccccc1)-c1nc2CCN(CCCC(O)=O)Cc2s1

BDBM597828

Cc1c(cccc1-c1ccccc1)-c1nc2CCN(CC3CC3C(O)=O)Cc2s1

BDBM597829

Cc1c(cccc1-c1ccccc1)-c1nc2CCN(Cc3cn[nH]c3)Cc2s1

BDBM597830

Cc1c(cccc1-c1ccccc1)-c1nc2CCN(Cc2s1)C1CCC(CC#N)CC1 |(-4.89,.82,;-4.89,-.72,;-3.56,-1.49,;-3.56,-3.03,;-4.89,-3.8,;-6.22,-3.03,;-6.22,-1.49,;-7.56,-.72,;-7.56,.82,;-8.89,1.59,;-10.22,.82,;-10.22,-.72,;-8.89,-1.49,;-2.22,-.72,;-2.06,.81,;-.56,1.13,;.21,2.47,;1.75,2.47,;2.52,1.13,;1.75,-.2,;.21,-.2,;-.82,-1.35,;4.06,1.13,;4.83,-.2,;6.37,-.2,;7.14,1.13,;8.68,1.13,;9.45,2.47,;10.22,3.8,;6.37,2.47,;4.83,2.47,)|

BDBM597831

Cc1c(cccc1-c1ccccc1)-c1cc2CNCCn2n1

BDBM597832

N#Cc1c(cccc1-c1ccc2OCCOc2c1)-c1nc2CCNCc2s1

BDBM597833

Cc1c(ccnc1-c1nc2CCNCc2s1)-c1ccccc1

BDBM597834

COc1cccc(c1)-c1ccnc(-c2nc3CCNCc3s2)c1C

BDBM597835

Cc1c(ccnc1-c1nc2CCNCc2s1)-c1ccc2OCCOc2c1

BDBM597836

Cc1c(nccc1-c1ccccc1)C1N=C2CCNCC2=N1 |c:23,t:16|

BDBM597838

Cc1c(cccc1-n1cc2CCNCc2n1)-c1ccccc1

BDBM597839

Cc1c(cccc1-c1ccccc1)-c1nc2c(CNCC2(C)C)s1

BDBM597840

Cc1c(cccc1-c1ccccc1)-c1cn2CCNCc2n1

BDBM597841

Cc1c(cccc1-c1ccccc1)-c1nc2CNCCc2[nH]1

BDBM597842

Cc1c(cccc1-c1ccccc1)-c1nc2CCNCc2o1

BDBM597843

Cc1c(cccc1-c1ccccc1)-c1nc2CNCCc2o1

BDBM597844

CN1CCc2oc(nc2C1)-c1cccc(-c2ccccc2)c1C

BDBM597845

Cc1c(cccc1-c1ccccc1)-c1nc2CNCCn2n1

BDBM597846

Cc1c(ccnc1-c1ccc2OCCOc2c1)-c1nc2CCNCc2s1

BDBM597847

Cc1c(cccc1-c1nc2CCNCc2s1)-c1ccsc1

BDBM597848

COc1cccc(c1)-c1cccc(-c2nc3CCNCc3s2)c1C

BDBM597849

Cc1c(cccc1C1=CCOCC1)-c1nc2CCNCc2s1 |t:8|

BDBM597850

COc1cc(ccn1)-c1cccc(-c2nc3CCNCc3s2)c1C

BDBM597852

Cc1c(cccc1-c1ccc(F)cn1)-c1nc2CCNCc2s1

BDBM597853

Cc1c(cccc1C1=CCCCC1)-c1nc2CCNCc2s1 |t:8|

BDBM597854

CCOc1cccc(c1)-c1cccc(-c2nc3CCNCc3s2)c1C

BDBM597855

COc1cc(OC)cc(c1)-c1cccc(-c2nc3CCNCc3s2)c1C

BDBM597856

N#Cc1c(ccnc1-c1nc2CCNCc2s1)-c1ccc2OCCOc2c1

BDBM597857

Cc1c(cccc1-c1cccc(OCCO)c1)-c1nc2CCNCc2s1

BDBM597858

COc1cc(OC)c(F)c(c1F)-c1cccc(-c2nc3CCNCc3s2)c1C |(-7.04,-3.08,;-7.04,-1.54,;-5.71,-.77,;-5.71,.77,;-4.37,1.54,;-4.37,3.08,;-3.04,3.85,;-3.04,.77,;-1.71,1.54,;-3.04,-.77,;-4.37,-1.54,;-4.37,-3.08,;-1.71,-1.54,;-1.71,-3.08,;-.37,-3.85,;.96,-3.08,;.96,-1.54,;2.29,-.77,;2.46,.76,;3.96,1.08,;4.73,2.42,;6.27,2.42,;7.04,1.08,;6.27,-.25,;4.73,-.25,;3.7,-1.4,;-.37,-.77,;-.37,.77,)|

BDBM597859

Cc1c(cccc1-c1cccc(c1)C(N)=O)-c1nc2CCNCc2s1

BDBM597860

Cc1c(cccc1-c1cccc(CC(N)=O)c1)-c1nc2CCNCc2s1

BDBM597861

Cc1c(cccc1-c1cccc2n(C)ncc12)-c1nc2CCNCc2s1

BDBM598702

Cc1c(NC(=O)c2ncc(CN3CCCC[C@H]3C(O)=O)s2)cccc1-c1ccccc1 |r|

BDBM598703

Cc1c(NC(=O)c2ncc(CNCCO)s2)cccc1-c1ccccc1

BDBM598704

Cc1c(NC(=O)c2ncc(CNCCO)o2)cccc1-c1ccccc1