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- 7BC7: cryo-em structure of the proton coupled folate transporter at ph 6.0 bound to pemetrexed (10.1038/S41586-021-03579-Z )
- 4LVY: structure of the thf riboswitch bound to pemetrexed (10.1016/J.CHEMBIOL.2013.11.012 )
- 1JUJ: human thymidylate synthase bound to dump and ly231514, a pyrrolo(2,3-d)pyrimidine-based antifolate (10.1006/JMBI.2001.5074 )
- 1JU6: human thymidylate synthase complex with dump and ly231514, a pyrrolo(2,3-d)pyrimidine-based antifolate (10.1006/JMBI.2001.5074 )
- 6SMW: a. thaliana serine hydroxymethyltransferase isoform 2 (atshmt2) in complex with pemetrexed (10.1038/S41598-019-56043-4 )
- 4KN2: human folate receptor beta (folr2) in complex with antifolate pemetrexed (10.1073/PNAS.1308827110 )
- 6NNC: structure of dihydrofolate reductase from mycobacterium tuberculosis in complex with nadph and pemetrexed (10.1107/S205979831900901X )
- 4FQS: crystal structure of mycobacterium tuberculosis thya in complex with ump and pemetrexed
- 8GOF: structure of hslc19a1+pmx (10.1038/S41586-022-05452-Z )
- 2X9G: high resolution structure of tbptr1 in complex with pemetrexed (10.1107/S0907444910040886 )
- 3K2H: co-crystal structure of dihydrofolate reductase/thymidylate synthase from babesia bovis with dump, pemetrexed and nadp (10.1107/S1744309111029009 )