BindingDB Webinars

BindingDB has started a series of free one-hour webinars designed to be of interest to our users. We aim to host talks by members of the BindingDB team, BindingDB users, and other experts. These events will be held 3-4 times a year and will include plenty of time for open-ended Q&A. We are excited to open this new forum and look forward to meeting many of you!

• Webinar 3: Building Machine Learning Models Using Data from BindingDB, Dr. Patrick Walters, Feb 24, 2026. View in YouTube
• Webinar 2: Synergies between BindingDB and PubChem, Dr. Christopher Southan, Sep 17, 2025. View in YouTube
• Webinar 1: BindingDB: A Massive, Publicly Accessible, Knowledgebase of Protein-Ligand Binding Data, Dr. Mike Gilson, Feb 27, 2025. View in YouTube

Recently Added Targets

1. Enoyl-[acyl-carrier-protein] reductase [NADH], Neisseria gonorrhoeae (strain NCCP11945), B4RNM9 (Curated 06/22/26), : 58 subμM ligands
2. 1-phosphatidylinositol 4-kinase, Plasmodium falciparum (isolate NF54), W7K9N9 (Curated 06/24/26), : 7 subμM ligands
3. Small VCP/p97-interacting protein, Human, Q8NHG7 (Curated 07/06/26), SVIP: 88 subμM ligands
4. HEAT repeat-containing protein 5A, Human, Q86XA9 (Curated 06/24/26), HEATR5A: 1 subμM ligands
5. High affinity 3',5'-cyclic-AMP phosphodiesterase 7A, Rat, O08593 (Curated 06/05/26), Pde7a: 1 subμM ligands
6. Chymase, Dog, P21842 (Curated 06/05/26), CMA1: 47 subμM ligands
7. Peptidyl-prolyl cis-trans isomerase, Burkholderia pseudomallei (strain K96243), Q63J95 (Curated 06/05/26), fbp: 2 subμM ligands
8. Macrophage infectivity potentiator, Trypanosoma cruzi, Q09734 (Curated 06/05/26), MIP: 2 subμM ligands
9. Deubiquitinase and deneddylase Dub1, Chlamydia trachomatis serovar L2 (strain ATCC VR-902B / DSM 19102 / 434/Bu), B0B9A0 (Curated 06/05/26), cdu1: 1 subμM ligands
10. NAD(+) hydrolase SARM1, Mouse, Q6PDS3 (Curated 06/05/26), Sarm1: 2 subμM ligands
11. NAD(+) hydrolase SARM1, Rat, D3ZUM2 (Curated 06/05/26), Sarm1: 2 subμM ligands
12. Activin receptor type-1C, Human, Q8NER5 (Curated 06/05/26), ACVR1C: 1 subμM ligands
13. Serine/threonine protein kinase YCK2, Yeast, A0A1D8PKB4 (Curated 06/05/26), YCK2: 12 subμM ligands
14. Interleukin-11, Human, P20809 (Curated 06/05/26), IL11: 1 subμM ligands
15. Fas-activated serine/threonine kinase, Human, Q14296 (Curated 06/05/26), FASTK: 3 subμM ligands
16. Phenazine biosynthesis protein PhzB 2, Pseudomonas aeruginosa (strain UCBPP-PA14), Q02L47 (Curated 06/05/26), phzB2: 1 subμM ligands
17. Branched-chain alpha-ketoacid dehydrogenase kinase, Mouse, O55028 (Curated 06/05/26), Bckdk: 1 subμM ligands
18. Serine/threonine-protein kinase PINK1, mitochondrial, Human, Q9BXM7 (Curated 06/06/26), PINK1: 2 subμM ligands
19. Nucleoprotein, 2019-nCoV, P0DTC9 (Curated 06/06/26), N: 1 subμM ligands
20. ATP-dependent chromatin remodeler CHD1, Human, O14646 (Curated 06/06/26), CHD1: 5 subμM ligands
21. Secernin-3, Human, Q0VDG4 (Curated 06/06/26), SCRN3: 1 subμM ligands
22. Sensor protein VraS, Staphylococcus aureus (strain N315), Q99SZ7 (Curated 06/06/26), vraS: 1 subμM ligands
23. Triggering receptor expressed on myeloid cells 2, Human, Q9NZC2 (Curated 06/06/26), TREM2: 6 subμM ligands
24. Hepatocyte nuclear factor 4-gamma, Human, Q14541 (Curated 06/06/26), HNF4G: 1 subμM ligands
25. Aquaporin-3, Human, Q92482 (Curated 06/06/26), AQP3: 1 subμM ligands
26. Aquaporin-3, Mouse, Q8R2N1 (Curated 06/06/26), Aqp3: 1 subμM ligands
27. Glutathione S-transferase class-mu 26 kDa isozyme, Blood fluke, P08515 (Curated 07/21/26), : 23 subμM ligands
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Analyze BindingDB data in Google Colab using this Python tool from Pat Walters

This tutorial shows how one can use the BindingDB database and a bit of Python scripting to quickly understand SAR in a pharmaceutical patent. The tutorial covers several patent-related tasks, including accessing BindingDB, exploring chemical scaffolds, performing R-group analyses, and identifying key SAR drivers. 

Coronavirus Binding Data

BindingDB has accelerated collection of COVID related data. You can find the result here.

Try the BindingDB Browser Extension

We are excited to share our new browser extension, BDBFind. Once installed in your browser, BDBFind automatically lets you know when BindingDB has the data from an article, PubMed Entry, or US Patent you are looking at online and provides direct links to view or download the data. Get BDBFind by searching for it in the Chrome webstore or in Firefox extensions or by following these links:

• https://chrome.google.com/webstore/search/bdbfind (Once installed, click on the "jigsaw puzzle" icon to keep the BDB icon displayed.)
• https://addons.mozilla.org/addon/bdbfind.

Watch BDBFind in action in this 1.5 minute video: To send feedback about BDBfind, please email us at bindingdb@gmail.com.

BindingDB Data Curation

BindingDB curates US Patents. We have scanned patents back to 2013 for suitable data and are currently up to date as of mid-2020. However, we cannot be sure of capturing all relevant patents, so if you know of a useful one we have missed, please let us know and we will try to curate it. As of July 26, 2026, BindingDB's patent dataset comprises:

1. Patents: 8,824
2. Binding measurements: 1,339,238
3. Compounds: 678,308
4. Target proteins: 3,165
5. Assays: 12,446
6. Average Number of Targets per Patent: 1.91

BindingDB curates a set of journals not covered by other public databases. As of July 26, 2026, the status of this curation effort is as follows:

• ACS Chemical Biology 2006-2017 (vol 1-12) ^data
• ACS BioChemistry 1965-2017 (vol 4-56) ^data
• Bioorganic Chemistry 1990-2017 (vol 18-73) ^data
• BMC Chemical Biology 2001-2010 (vol 1-10) ^data
• ChemBioChem 2001-2017 (vol 2-18) ^data
• Chemical Biology & Drug Design 2006-2017 (vol 67-89) ^data
• Chemistry & Biology 1995-2015 (vol 2-22) ^data
• Journal of Biological Chemistry 1982-2014 (vol 257-289) ^data
• Journal of Chemical Biology 2010-2010 (vol 3-3) ^data
• Journal of Enzyme Inhibition and Medicinal Chemistry 2002-2014 (vol 17-29) ^data
• Nature Chemical Biology 2006-2017 (vol 1-13) ^data
• Medicinal Chemistry Research 2004-2014 (vol 13-23) ^data