Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-JNJ962 from BACE1 (unknown origin) expressed in HEK293 cell membrane assessed as inhibition constant by scintillation counting a...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Leiden University
Curated by PDSP Ki Database
Leiden University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Leiden University
Curated by PDSP Ki Database
Leiden University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Leiden University
Curated by PDSP Ki Database
Leiden University
Curated by PDSP Ki Database
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-JNJ962 from BACE2 (unknown origin) expressed in HEK293 cell membrane assessed as inhibition constant by scintillation counting a...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Leiden University
Curated by PDSP Ki Database
Leiden University
Curated by PDSP Ki Database
Affinity DataKi: 60nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Leiden University
Curated by PDSP Ki Database
Leiden University
Curated by PDSP Ki Database
Affinity DataKi: 360nMAssay Description:Binding affinity to Actinomadura sp. R39 PBPMore data for this Ligand-Target Pair
Affinity DataKi: 730nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]-imipramine from recombinant human 5-HT transporter after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.15E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Binding affinity to Actinomadura sp. R39 PBPMore data for this Ligand-Target Pair
Affinity DataKi: 1.55E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.58E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.77E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.81E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.84E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.89E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.93E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.96E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.36E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.41E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.69E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.89E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.94E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.15E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.23E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.66E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.04E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.49E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 7.20E+3nMAssay Description:Displacement of [3H]-pirenzepine from human recombinant muscarinic 1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair