TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 205nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase/reductase(Mycobacterium tuberculosis)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC/RmlD expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 409nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 652nMAssay Description:Inhibitory activity against human SIRT1 by radiochemical Nicotinamide release assayMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human liver cathepsin B preincubated for 17 hrs in buffer without DTTMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibitory activity against human SIRT1 by radiochemical Nicotinamide release assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human liver cathepsin B preincubated for 2 hrs in buffer without DTTMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human liver cathepsin B preincubated for 2 hrs in non-buffer solution without DTTMore data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human liver cathepsin B preincubated for 17 hrs in non-buffer solution without DTTMore data for this Ligand-Target Pair
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against human SIRT1 by radiochemical Nicotinamide release assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibitory activity against recombinant human SIRT2 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human liver cathepsin B preincubated for 24 hrs in buffer without DTTMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against human SIRT1 by radiochemical Nicotinamide release assayMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human liver cathepsin B preincubated for 24 hrs in non-buffer solution without DTTMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human liver cathepsin B preincubated for 2 hrs in assay buffer with DTTMore data for this Ligand-Target Pair
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlC expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibitory activity against recombinant human SIRT2 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Elixir Pharmaceuticals
Curated by ChEMBL
Elixir Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair