Affinity DataKi: 1.70nMAssay Description:Inhibition of human recombinant IDE expressed in CHO cells in presence of [125I]-insulin by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Binding affinity to Staphylococcus aureus biotin protein ligaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Binding affinity to Bacillus subtilis ErmC' methyltransferase assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Binding affinity to Bacillus subtilis ErmC' methyltransferase assessed as inhibition constantMore data for this Ligand-Target Pair
TargetNAD kinase 1(Listeria monocytogenes serovar 1/2a (strain ATCC B...)
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: 2.50E+4nMAssay Description:Inhibition of Listeria monocytogenes NAD kinase assessed as suppression of reduced NADP formation by yeast glucose-6-phosphate dehydrogenase coupled ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: 4.20E+5nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Affinity DataKi: 6.80E+5nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+6nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.398nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C gamma C1b domainMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:In vitro displacement of [3H]- SCH 23390 from the dopamine receptor D1 of bovine striatal membraneMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.501nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.501nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporterMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Compound was tested for its ability to inhibit high-affinity uptake of [3H]NE into parietal and occipital cortex in ratMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D2 short form expressed in CHO cellsMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C delta C1a domainMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 5 using HEK293 cellsMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair