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Found 35 with Last Name = 'jha' and Initial = 'bk'
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570891(CHEMBL4872206)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of TET2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET1(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant human N-terminal Flag-tagged TET1 (1418 to 2136 residues) expressed in Baculovirus infected Sf9 cells assessed as reduction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET3(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570891(CHEMBL4872206)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of TET3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET1(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570891(CHEMBL4872206)
Affinity DataIC50:  3.48E+3nMAssay Description:Inhibition of TET1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET3(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant human N-terminal Flag-tagged C-terminal His-tagged TET3 (824 to 1795 residues) expressed in Baculovirus infected Sf9 cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570898(CHEMBL4860506)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570897(CHEMBL4872110)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
TargetMethylcytosine dioxygenase TET1(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50508775(CHEMBL4457636)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of TET1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570894(CHEMBL4855677)
Affinity DataIC50:  5.48E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50508775(CHEMBL4457636)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of TET2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570896(CHEMBL4847806)
Affinity DataIC50:  1.07E+5nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570895(CHEMBL4859276)
Affinity DataIC50:  1.08E+5nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570892(CHEMBL4870693)
Affinity DataIC50:  2.62E+5nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373177(CHEMBL404038)
Affinity DataKd:  0.220nMAssay Description:Displacement of 5'-phosphorylated, 2',5'-oligoadenylate from human recombinant RNase L assessed as decrease in resonance by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570892(CHEMBL4870693)
Affinity DataKd:  3.42E+3nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataKd:  300nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570894(CHEMBL4855677)
Affinity DataKd:  610nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373177(CHEMBL404038)
Affinity DataEC50:  0.5nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373177(CHEMBL404038)
Affinity DataKd:  0.0400nMAssay Description:Binding affinity to human recombinant recombinant RNase LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373176(C-5950331 | CHEMBL259633)
Affinity DataKd:  1.20E+4nMAssay Description:Displacement of 5'-phosphorylated, 2',5'-oligoadenylate from human recombinant RNase L assessed as decrease in resonance by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373166(CHEMBL259819)
Affinity DataKd:  1.80E+4nMAssay Description:Displacement of 5'-phosphorylated, 2',5'-oligoadenylate from human recombinant RNase L assessed as decrease in resonance by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373176(C-5950331 | CHEMBL259633)
Affinity DataEC50:  2.20E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373175(C-5972155 | CHEMBL411931)
Affinity DataEC50:  4.90E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373174(C-6131864 | CHEMBL265469)
Affinity DataEC50:  7.90E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373173(CHEMBL410485)
Affinity DataEC50:  4.90E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373172(C-6474572 | CHEMBL265438)
Affinity DataEC50:  2.60E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373171(CHEMBL260229)
Affinity DataEC50:  5.00E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373170(CHEMBL408340)
Affinity DataEC50:  9.00E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373169(C-5142087 | CHEMBL259804)
Affinity DataEC50:  2.20E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373168(C-5947495 | CHEMBL261864)
Affinity DataEC50:  4.80E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570895(CHEMBL4859276)
Affinity DataKd:  2.05E+3nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373166(CHEMBL259819)
Affinity DataEC50:  2.60E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373167(CHEMBL406556)
Affinity DataEC50:  9.90E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed