Affinity DataKi: 64nMAssay Description:Inhibition of human recombinant full length MMP13 by steady state kinetic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human recombinant MMP13 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of MMP17 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of MMP14 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of MMP12 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human recombinant MMP13 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of MMP3 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Inhibition of MMP8 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MMP13 catalytic domainMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant full length MMP13-mediated type 2 collagen cleavageMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of PDE4B catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Inhibition of PDE4B catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 259nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 265nMAssay Description:Inhibition of PDE4B catalytic domain (unknown origin)More data for this Ligand-Target Pair