Affinity DataKi: 26nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.02E+3nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.07E+3nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.77E+3nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.77E+3nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.77E+3nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.77E+3nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:Inhibition of human dopamine D2L receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:Inhibition of human dopamine D2L receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.08E+4nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.57E+4nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.59E+4nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.00500nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.00500nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.00600nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00700nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.00800nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.00800nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.0100nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.0100nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.0100nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.0100nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.0130nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.0130nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair