Found 340 with Last Name = 'marques' and Initial = 'c' 
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of Equine serum BuChE assessed as inhibitory constants for binding the free enzyme using S-butyrylthiocholine iodide as a substrate by Cor...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 2.45E+3nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition b...More data for this Ligand-Target Pair
Affinity DataKi: 6.70E+3nMAssay Description:Inhibition of Equine serum BuChE assessed as inhibitory constants for binding the enzyme-substrate complex using S-butyrylthiocholine iodide as a sub...More data for this Ligand-Target Pair
Affinity DataKi: 7.20E+3nMAssay Description:Inhibition of Equine serum BuChE assessed as inhibitory constants for binding the free enzyme using S-butyrylthiocholine iodide as a substrate by Cor...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 7.76E+3nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition b...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 8.42E+3nMAssay Description:Apparent affinity to inhibit binding of [3H]-pCCK-8 to Cholecystokinin type A receptor of guinea pig pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 9.00E+3nMAssay Description:Inhibition of Equine serum BuChE assessed as inhibitory constants for binding the free enzyme using S-butyrylthiocholine iodide as a substrate by Cor...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 9.70E+3nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of Equine serum BuChE assessed as inhibitory constants for binding the enzyme-substrate complex using S-butyrylthiocholine iodide as a sub...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 1.15E+4nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition b...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 1.34E+4nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition b...More data for this Ligand-Target Pair
Affinity DataKi: 1.37E+4nMAssay Description:Inhibition of Equine serum BuChE assessed as inhibitory constants for binding the enzyme-substrate complex using S-butyrylthiocholine iodide as a sub...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of Equine serum BuChE assessed as inhibitory constants for binding the free enzyme using S-butyrylthiocholine iodide as a substrate by Cor...More data for this Ligand-Target Pair
Affinity DataKi: 1.91E+4nMAssay Description:Inhibition of Equine serum BuChE assessed as inhibitory constants for binding the enzyme-substrate complex using S-butyrylthiocholine iodide as a sub...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 2.11E+4nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition b...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Apparent affinity to inhibit binding of [3H]-pCCK-8 to Cholecystokinin type A receptor of guinea pig pancreatic membranesMore data for this Ligand-Target Pair
3D Structure (crystal)TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of A23187 and measured af...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as a substrate and measured upto 180 sec by DTNB based Ellman's methodMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
