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Found 65 with Last Name = 'muratspahi?' and Initial = 'e'
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.200nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.300nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(Dynorphin A (1-17) | YGGFLRRIRPKLK)
Affinity DataKi:  0.300nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50002184(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  8.10nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  10nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  15nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  15nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  17nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580697(CHEMBL5071625)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  36nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580681(CHEMBL5070568)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580695(CHEMBL5077697)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580695(CHEMBL5077697)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580694(CHEMBL5091699)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580693(CHEMBL5087018)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580680(CHEMBL5070898)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580696(CHEMBL5088478)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574768(CHEMBL4848577)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]-DPN from mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]-DPN from mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580691(CHEMBL5075196)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580683(CHEMBL5093924)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580682(CHEMBL5079877)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580690(CHEMBL5076021)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580697(CHEMBL5071625)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580684(CHEMBL5080221)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580697(CHEMBL5071625)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse MOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580692(CHEMBL5076587)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580685(CHEMBL5075574)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580686(CHEMBL5083929)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580687(CHEMBL5070737)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580688(CHEMBL5087338)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580689(CHEMBL5081959)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50554438(CHEMBL4796244)
Affinity DataIC50:  11nMAssay Description:Inhibition of full length recombinant human POP expressed in Escherichia coli BL21 cells using Z-Gly-Pro-AMC as substrate measured for 5 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574768(CHEMBL4848577)
Affinity DataEC50:  6.02E+4nMAssay Description:Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50580697(CHEMBL5071625)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at EGFP-tagged mouse KOR expressed in HEK293 cells co-expressing beta-arrestin2 nano-luciferase assessed as beta-arrestin2 recruitme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(Dynorphin A (1-17) | YGGFLRRIRPKLK)
Affinity DataEC50:  159nMAssay Description:Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as beta-arrestin 2 recruitment using furimazine as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(Dynorphin A (1-17) | YGGFLRRIRPKLK)
Affinity DataEC50:  6.70nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  6.80nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  5nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  8.80nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  8.80nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  17nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataEC50:  1.70nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  0.800nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Medical University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  0.900nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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