TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of MMP-9 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of MMP-9 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of MMP-9 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of MMP-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of MMP-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of MMP-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of MMP-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of MMP-9 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Inhibition of MMP-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of MMP-13 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 131nMAssay Description:Inhibition of MMP-13 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 139nMAssay Description:Inhibition of MMP-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 221nMAssay Description:Inhibition of MMP-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 266nMAssay Description:Inhibition of MMP-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of MMP-13 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 295nMAssay Description:Inhibition of MMP-13 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair