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Found 67 with Last Name = 'rhee' and Initial = 'hk'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304572(5-Oxo-5,6-dihydro-pyrido[2',1':2,3]imidazo[4,5-c]i...)
Affinity DataIC50:  36nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329397(CHEMBL1269648 | N-(4-Ethylphenyl)-5-methylbenzo[d]...)
Affinity DataIC50:  120nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324078(1-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-y...)
Affinity DataIC50:  190nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324082(4-(4-Isopropylbenzylamino)-1-(4-((4-chlorophenyl)(...)
Affinity DataIC50:  280nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324076(1-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-y...)
Affinity DataIC50:  360nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324075(1-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-y...)
Affinity DataIC50:  420nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304575(10-Methyl-6H-pyrido[2',1':1,2]imidazo[5,4-c]isoqui...)
Affinity DataIC50:  470nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304570(10-Methyl-pyrimido[1',2':1,2]imidazo[5,4-c]isoquin...)
Affinity DataIC50:  560nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324080(4-(4-Nitrobenzylamino)-1-(4-((4-chlorophenyl)(phen...)
Affinity DataIC50:  600nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304573(CHEMBL596091 | Pyrido[2',1':2,3]imidazo[4,5-c]isoq...)
Affinity DataIC50:  850nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329394(5-Chloro-N-(4-ethylphenyl)benzo[d]oxazol-2-amine |...)
Affinity DataIC50:  950nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117922((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of T-type Cav3.3 channelMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117922((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of T-type Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117922((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of T-type Cav3.1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324084(4-(2,6-Dichlorobenzylamino)-1-(4-((4-chlorophenyl)...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329392(CHEMBL1269619 | N-(4-Ethylphenyl)benzo[d]oxazol-2-...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117922((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324077(4-(2-Ethylbutylamino)-1-(4-((4-chlorophenyl)(pheny...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324079(4-(Benzylamino)-1-(4-((4-chlorophenyl)(phenyl)meth...)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329404(CHEMBL1269727 | N-(3-Bromophenyl)-5-methoxybenzo[d...)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324083(4-(4-(Dimethylamino)benzylamino)-1-(4-((4-chloroph...)
Affinity DataIC50:  2.32E+3nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329402(CHEMBL1269907 | N-(4-Isopropylphenyl)-5-methoxyben...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329403(5-Methoxy-N-(4-(methylthio)phenyl)benzo[d]oxazol-2...)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304567(6H-Pyrimido[4',3':1,2]imidazo[5,4-c]isoquinolin-5-...)
Affinity DataIC50:  3.23E+3nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304574(11-Methyl-6H-pyrido[2',1':1,2]imidazo[5,4-c]isoqui...)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324074(4-amino-1-(4-((4-chlorophenyl)(phenyl)methyl)piper...)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304569(6H-Naphto[2',1':1,2]imidazo[5,4-c]isoquinolin-5-on...)
Affinity DataIC50:  4.11E+3nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304576(9-Methyl-6H-pyrido[2',1':1,2]imidazo[5,4-c]isoquin...)
Affinity DataIC50:  4.27E+3nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329393(5-Chloro-N-phenylbenzo[d]oxazol-2-amine | CHEMBL12...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329396(5-Methyl-N-phenylbenzo[d]oxazol-2-amine | CHEMBL12...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329398(CHEMBL1269649 | N-(2-Ethylphenyl)-5-methylbenzo[d]...)
Affinity DataIC50:  5.66E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304568(6H-Pyrimido[1',2':1,2]imidazo[5,4-c]isoquinolin-5-...)
Affinity DataIC50:  5.78E+3nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304565(10-Chloro-6H-pyrido[2',1':1,2]imidazo[5,4-c]isoqui...)
Affinity DataIC50:  5.87E+3nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329400(CHEMBL1269704 | N-(3-Methoxyphenyl)-5-methylbenzo[...)
Affinity DataIC50:  6.83E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329399(6-Methyl-N-(4-(methylthio)phenyl)benzo[d]oxazol-2-...)
Affinity DataIC50:  7.31E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329401(5-Methoxy-N-phenylbenzo[d]oxazol-2-amine | CHEMBL1...)
Affinity DataIC50:  7.88E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM49481(1,3-benzoxazol-2-yl(phenyl)amine | CHEMBL1269508 |...)
Affinity DataIC50:  8.91E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM27502(3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoq...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304579(9-Bromo-6H-pyrido[2',1':1,2]imidazo[5,4-c]isoquino...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50304578(9-Chloro-6H-pyrido[2',1':1,2]imidazo[5,4-c]isoquin...)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50324081(4-(4-Methoxybenzylamino)-1-(4-((4-chlorophenyl)(ph...)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of T-type alpha1G channel expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50376172(CHEMBL261294)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329395(CHEMBL1269906 | N-(4-Ethylphenyl)-5-nitrobenzo[d]o...)
Affinity DataIC50:  2.39E+4nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50376185(CHEMBL259225)
Affinity DataIC50:  2.86E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50376173(CHEMBL261341)
Affinity DataIC50:  2.98E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50376175(CHEMBL260224)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50376183(CHEMBL259778)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50201614(3-[2-(dimethylamino)propoxy]benzo[b]naphtho[2,3-d]...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of human topoisomerase 1 at 200 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50376177(CHEMBL260541)
Affinity DataIC50:  4.32E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50376178(CHEMBL261330)
Affinity DataIC50:  4.44E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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