TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 11.8nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 12.9nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 13.1nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 14.8nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 17.6nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 23.9nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of MIP-1beta stimulated calcium transients in CCR5-expressing CHO cellsMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Bos taurus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against microsomal triglyceride transfer protein (MTP)More data for this Ligand-Target Pair