Found 48 with Last Name = 'kessl' and Initial = 'jj' TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
The Ohio State University
The Ohio State University
Affinity DataIC50: 170nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
The Ohio State University
The Ohio State University
Affinity DataIC50: 180nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
The Ohio State University
The Ohio State University
Affinity DataIC50: 400nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase A128T mutant expressed in Escherichia coli BL21(DE3) cells assessed as red...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
The Ohio State University
The Ohio State University
Affinity DataIC50: 910nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as reduction in LED...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
Affinity DataIC50: 4.61E+3nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged LEDGF/p75 binding to recombinant full length N-terminal His-tagged HIV1 integrase expressed in Escherichia coli ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
Affinity DataIC50: 5.91E+4nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+5nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.79E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.21E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 510nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 580nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.38E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 950nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.97E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.11E+4nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.32E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.61E+4nMAssay Description:Inhibition of recombinant full length HIV1 C-terminal His-tagged integrase multimerization with N-terminal FLAG-tagged integrase expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataEC50: 2.11E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Inhibition of recombinant full length HIV1 C-terminal His-tagged integrase A128T mutant multimerization with N-terminal FLAG-tagged integrase A128T m...More data for this Ligand-Target Pair
Affinity DataEC50: 8.41E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 720nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.39E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 260nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.51E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.39E+3nMAssay Description:Inhibition of N-terminal His/flag-tagged HIV1 integrase expressed in Escherichia coli BL21 (DE3) incubated for 2.5 hrs by HTRF assayMore data for this Ligand-Target Pair
