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Found 68 with Last Name = 'mallion' and Initial = 'kb'
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029174(CHEMBL131973 | N-(1-methylethyl)-3-[(3-prop-2-en-1...)
Affinity DataIC50:  0.00400nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029177(CHEMBL134337 | Propionic acid 3-allyl-4-(3-isoprop...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029166(Acetaldehyde O-[3-allyl-4-(3-isopropylamino-propox...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029159(CHEMBL132881 | [3-(2-Allyl-4-butoxy-phenoxy)-propy...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029171(CHEMBL341371 | N-[3-Benzyl-4-(3-isopropylamino-pro...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029179(1-[3-Allyl-4-(3-isopropylamino-propoxy)-phenyl]-bu...)
Affinity DataIC50:  1nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052343(3-Biphenyl-4-ylethynyl-1-aza-bicyclo[2.2.2]octan-3...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029163(CHEMBL340992 | Propionic acid 4-(3-isopropylamino-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052350(3-((E)-2-Biphenyl-4-yl-vinyl)-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029170(1-[3-Allyl-4-(2-hydroxy-3-isopropylamino-propoxy)-...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029161(CHEMBL433864 | N-{3-Allyl-4-[3-(isopropyl-methyl-a...)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052342(3-(2-Biphenyl-4-yl-ethyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052353(3-(4-Benzothiazol-2-yl-phenyl)-1-aza-bicyclo[2.2.2...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052355(3-(2-Biphenyl-4-yl-ethyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052377(3-(Biphenyl-4-ylsulfanylmethyl)-1-aza-bicyclo[2.2....)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052376(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octane | CHEMB...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029172(CHEMBL131930 | [3-(2-Benzyl-phenoxy)-propyl]-isopr...)
Affinity DataIC50:  12nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052358(3-(Biphenyl-4-yloxymethyl)-1-aza-bicyclo[2.2.2]oct...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052366(3-(4'-Fluoro-biphenyl-4-yl)-1-aza-bicyclo[2.2.2]oc...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052352(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]oct-2-ene | CH...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052367(3-(Biphenyl-4-ylsulfanyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052357(3-Biphenyl-4-ylmethyl-1-aza-bicyclo[2.2.2]octane |...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052341(3-(4-Pyrimidin-2-yl-phenyl)-1-aza-bicyclo[2.2.2]oc...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052372(3-(4-Thiazol-2-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052364(3-(4-Thiophen-2-yl-phenyl)-1-aza-bicyclo[2.2.2]oct...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029165(CHEMBL132207 | [3-(4-Butoxy-phenoxy)-propyl]-isopr...)
Affinity DataIC50:  56nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029181(CHEMBL134211 | [3-(2-Allyl-phenoxy)-propyl]-isopro...)
Affinity DataIC50:  56nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052373(3-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylo...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052362(3-(2-Phenyl-thiazol-5-yl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052344(3-Biphenyl-3-yl-1-aza-bicyclo[2.2.2]octan-3-ol | C...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029168(CHEMBL133996 | N-[3-Allyl-4-(3-isopropylamino-prop...)
Affinity DataIC50:  65nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052361(3-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylo...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)
Affinity DataIC50:  121nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052359(3-(4'-Hydroxy-biphenyl-4-yl)-1-aza-bicyclo[2.2.2]o...)
Affinity DataIC50:  132nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052354((1-Aza-bicyclo[2.2.2]oct-3-yl)-biphenyl-4-ylmethyl...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052345(3-(4-Pyridin-4-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50:  161nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029169(CHEMBL134210 | [3-(Biphenyl-4-yloxy)-propyl]-isopr...)
Affinity DataIC50:  170nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052356(3-(4-Cyclohexyl-phenyl)-1-aza-bicyclo[2.2.2]octan-...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052360(3-(4-Quinolin-3-yl-phenyl)-1-aza-bicyclo[2.2.2]oct...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052378(3-(4-Pyridin-2-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029162(3-Allyl-4-(3-isopropylamino-propoxy)-phenylamine |...)
Affinity DataIC50:  250nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052374(3-(4-Pyridin-3-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052349(3-[1,1';4',1'']Terphenyl-4-yl-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50:  370nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052346(3-((Z)-2-Biphenyl-4-yl-vinyl)-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50:  580nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029175(CHEMBL337731 | [3-(Biphenyl-3-yloxy)-propyl]-isopr...)
Affinity DataIC50:  600nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029176(CHEMBL334964 | N-[3-Benzyl-4-(2-hydroxy-3-isopropy...)
Affinity DataIC50:  900nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052371(Biphenyl-4-carboxylic acid (1-aza-bicyclo[2.2.2]oc...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029182(4-(2-Hydroxy-3-isopropylamino-propoxy)-benzoic aci...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029164(CHEMBL133161 | N-[4-(3-Isopropylamino-propoxy)-phe...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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