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TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046798(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.240nMpH: 7.4Assay Description:In vitro inhibitory concentration against monkey plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014049(CHEMBL287953 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  0.320nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006122(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.360nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014052(CHEMBL445350 | {1-[1-(4-Azido-1-cyclohexylmethyl-2...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006125(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.470nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014059(CHEMBL38954 | {1-[1-[1-Cyclohexylmethyl-2-(3-ethyl...)
Affinity DataIC50:  0.630nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006138(2-(Morpholine-4-carbonyl)-3-phenyl-cyclopropanecar...)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:In vitro potency against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014060(CHEMBL288346 | {1-[1-{1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014048(CHEMBL41303 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  0.710nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046799(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  0.720nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046794(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  0.760nMpH: 7.4Assay Description:In vitro inhibitory concentration against monkey plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046802(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  0.800nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014053(CHEMBL416429 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  0.840nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046796((S)-N-[(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-di...)
Affinity DataIC50:  0.870nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014063(CHEMBL290215 | {1-[1-[1-Cyclohexylmethyl-2-(4,4-di...)
Affinity DataIC50:  0.890nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014054((5R){1-[1-[1-Cyclohexylmethyl-2-hydroxy-2-(3-metho...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014056(CHEMBL290605 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046798(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  1.10nMpH: 7.4Assay Description:In vitro inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046798(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  1.10nMpH: 7.4Assay Description:In vitro inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006123(2,3-Diphenyl-cyclopropanecarboxylic acid [1-(1-cyc...)
Affinity DataIC50:  1.10nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014051(CHEMBL273771 | {1-[1-[1-Cyclohexylmethyl-2-(1-ethy...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014047(CHEMBL291119 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014045(CHEMBL40053 | {1-[1-[1-Cyclohexylmethyl-2-(3-ethox...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046801(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011228((R)-2-Benzyl-N-[(S)-1-[(1S,2R)-1-cyclohexylmethyl-...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014057(CHEMBL288272 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014055(CHEMBL288347 | {1-[1-[1-Cyclohexylmethyl-2-(5-ethy...)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014062(CHEMBL289144 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011713(CHEMBL430933 | {1-[1-(1-Cyclohexylmethyl-2,3-dihyd...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046806(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022647(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046808(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046805(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  1.80nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006128(2-Isobutyl-3-(morpholine-4-carbonyl)-cyclopropanec...)
Affinity DataIC50:  2.10nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014049(CHEMBL287953 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  2.30nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006132(CHEMBL297929 | [1-[1-(1-Cyclohexylmethyl-2,3-dihyd...)
Affinity DataIC50:  2.40nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046794(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  2.60nMpH: 7.4Assay Description:In vitro inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014059(CHEMBL38954 | {1-[1-[1-Cyclohexylmethyl-2-(3-ethyl...)
Affinity DataIC50:  2.80nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014063(CHEMBL290215 | {1-[1-[1-Cyclohexylmethyl-2-(4,4-di...)
Affinity DataIC50:  2.80nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046785(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  2.80nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014046(CHEMBL289145 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046800(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  3nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014047(CHEMBL291119 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014061(CHEMBL288411 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  3.10nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046781(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  3.5nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046809(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  3.90nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046811(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  4nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046792(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  4.10nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046797(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  4.10nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014058(CHEMBL289146 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  4.70nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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