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Found 163 with Last Name = 'laakso' and Initial = 'lm'
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181002((S)-N-hydroxy-2,2-dimethyl-4-(4-(prop-2-ynyloxy)ph...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181002((S)-N-hydroxy-2,2-dimethyl-4-(4-(prop-2-ynyloxy)ph...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181006((S)-4-(4-(but-3-ynyloxy)phenylsulfonyl)-N-hydroxy-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181006((S)-4-(4-(but-3-ynyloxy)phenylsulfonyl)-N-hydroxy-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180999((S,E)-4-(4-(but-2-enyloxy)phenylsulfonyl)-N-hydrox...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181007((S)-tert-butyl 6-(4-(3-(hydroxycarbamoyl)-2,2-dime...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM23498((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171543(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171543(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181018((S)-tert-butyl 4-(4-(3-(hydroxycarbamoyl)-2,2-dime...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180997((S)-tert-butyl 7-(4-(3-(hydroxycarbamoyl)-2,2-dime...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181004((S)-N-hydroxy-2,2-dimethyl-4-(4-(penta-2,4-diynylo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181005((S)-4-(4-(hept-2-ynyloxy)phenylsulfonyl)-N-hydroxy...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181016((S)-4-(4-(7-aminohept-2-ynyloxy)phenylsulfonyl)-N-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180999((S,E)-4-(4-(but-2-enyloxy)phenylsulfonyl)-N-hydrox...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171543(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181003((S)-4-(4-butoxyphenylsulfonyl)-N-hydroxy-2,2-dimet...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181001((S)-tert-butyl 5-(4-(3-(hydroxycarbamoyl)-2,2-dime...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181013(2-((2S,5S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-5-(...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM23498((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171543(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171543(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181008((S)-N-hydroxy-4-(4-(4-hydroxybut-2-ynyloxy)phenyls...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM23498((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)
Affinity DataIC50:  8nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181012((S)-N-hydroxy-2,2-dimethyl-4-(4-(pent-4-ynyloxy)ph...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171534(1-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-2-c...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180995((S)-4-(4-(4-aminobut-2-ynyloxy)phenylsulfonyl)-N-h...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171543(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171534(1-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-2-c...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171540(4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarba...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181017((S)-4-(4-(6-aminohex-2-ynyloxy)phenylsulfonyl)-N-h...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171540(4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarba...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181003((S)-4-(4-butoxyphenylsulfonyl)-N-hydroxy-2,2-dimet...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171540(4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarba...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171540(4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarba...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171541(9-(4-But-2-ynyloxy-benzenesulfonyl)-6-thia-9-aza-s...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180994((3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydr...)
Affinity DataIC50:  11nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171541(9-(4-But-2-ynyloxy-benzenesulfonyl)-6-thia-9-aza-s...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181012((S)-N-hydroxy-2,2-dimethyl-4-(4-(pent-4-ynyloxy)ph...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50181004((S)-N-hydroxy-2,2-dimethyl-4-(4-(penta-2,4-diynylo...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171543(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against matrix metallopeptidase 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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