TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 111nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of Notch1 deltaE mutant (unknown origin) expressed in HEK293 cells after 16 hrs by resazurin dye-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 149nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of Notch1 deltaE mutant (unknown origin) expressed in HEK293 cells after 16 hrs by resazurin dye-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 255nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of Notch1 deltaE mutant (unknown origin) expressed in HEK293 cells after 16 hrs by resazurin dye-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of Notch1 deltaE mutant (unknown origin) expressed in HEK293 cells after 16 hrs by resazurin dye-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 364nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair