Affinity DataKi: 0.790nMAssay Description:Compound was tested for binding affinity towards mu opioid receptor in guinea pig brain homogenates using [3H]-CTOP as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Compound was tested for binding affinity towards mu opioid receptor in guinea pig brain homogenates using [3H]-CTOP as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 0.950nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding affinity to KOR (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Compound was tested for binding affinity towards mu opioid receptor in guinea pig brain homogenates using [3H]-CTOP as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity to MOR (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Compound was tested for binding affinity towards mu opioid receptor in guinea pig brain homogenates using [3H]-CTOP as radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Trieste
Curated by ChEMBL
University of Trieste
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity to DOR (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Compound was tested for binding affinity towards mu opioid receptor in guinea pig brain homogenates using [3H]-CTOP as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Compound was tested for binding affinity towards mu opioid receptor in guinea pig brain homogenates using [3H]-CTOP as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Trieste
Curated by ChEMBL
University of Trieste
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Trieste
Curated by ChEMBL
University of Trieste
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Compound was tested for binding affinity towards Opioid receptor delta 1 in guinea pig brain homogenates using [3H]-[p-Cl-Phe]-DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Compound was tested for binding affinity towards Opioid receptor delta 1 in guinea pig brain homogenates using [3H]-[p-Cl-Phe]-DPDPE as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Compound was tested for binding affinity towards Opioid receptor delta 1 in guinea pig brain homogenates using [3H]-[p-Cl-Phe]-DPDPE as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Compound was tested for binding affinity towards Opioid receptor delta 1 in guinea pig brain homogenates using [3H]-[p-Cl-Phe]-DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human Caspase 1More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Trieste
Curated by ChEMBL
University of Trieste
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Trieste
Curated by ChEMBL
University of Trieste
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 9.90nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
University of Trieste
Curated by ChEMBL
University of Trieste
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]ifenprodil from GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by s...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Trieste
Curated by ChEMBL
University of Trieste
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Compound was tested for binding affinity towards Opioid receptor delta 1 in guinea pig brain homogenates using [3H]-[p-Cl-Phe]-DPDPE as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Trieste
Curated by ChEMBL
University of Trieste
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Trieste
Curated by ChEMBL
University Of Trieste
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair