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Found 2314 with Last Name = 'roy' and Initial = 'm'
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552746(CHEMBL4759259 | US20240067660, Compound 28)
Affinity DataKi:  0.0900nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552743(CHEMBL4781303 | US20240067660, Compound 17)
Affinity DataKi:  0.130nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656135(US20240067660, Compound 35)
Affinity DataKi:  0.140nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656138(US20240067660, Compound 38)
Affinity DataKi:  0.150nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656140(US20240067660, Compound 40)
Affinity DataKi:  0.160nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552743(CHEMBL4781303 | US20240067660, Compound 17)
Affinity DataKi:  0.170nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute of Harvard and Mit

LigandPNGBDBM19423(HDAC inhibitor, Compound 1 | N-[2-amino-5-(thiophe...)
Affinity DataKi: <0.200nM ΔG°: <-55.4kJ/mole IC50:  1nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552745(CHEMBL4792037 | US20240067660, Compound 25)
Affinity DataKi:  0.200nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156774(CHEMBL3792888)
Affinity DataKi:  0.200nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656134(US20240067660, Compound 34)
Affinity DataKi:  0.210nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552745(CHEMBL4792037 | US20240067660, Compound 25)
Affinity DataKi:  0.210nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552740(CHEMBL4743213 | US20240067660, Compound 9)
Affinity DataKi:  0.220nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552747(CHEMBL4795415 | US20240067660, Compound 36)
Affinity DataKi:  0.230nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552740(CHEMBL4743213 | US20240067660, Compound 9)
Affinity DataKi:  0.230nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656121(US20240067660, Compound 18)
Affinity DataKi:  0.240nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656121(US20240067660, Compound 18)
Affinity DataKi:  0.240nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552748(CHEMBL4784541 | US20240067660, Compound 41)
Affinity DataKi:  0.25nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656117(US20240067660, Compound 14)
Affinity DataKi:  0.340nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656122(US20240067660, Compound 19)
Affinity DataKi:  0.360nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656106(US20240067660, Compound 27)
Affinity DataKi:  0.390nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156799(CHEMBL3793004)
Affinity DataKi:  0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156788(CHEMBL3794104)
Affinity DataKi:  0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156784(CHEMBL3792673)
Affinity DataKi:  0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656122(US20240067660, Compound 19)
Affinity DataKi:  0.430nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656137(US20240067660, Compound 37)
Affinity DataKi:  0.450nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656126(US20240067660, Compound 24)
Affinity DataKi:  0.470nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552742(CHEMBL4750960 | US20240067660, Compound 13)
Affinity DataKi:  0.490nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552742(CHEMBL4750960 | US20240067660, Compound 13)
Affinity DataKi:  0.510nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156782(CHEMBL3792663)
Affinity DataKi:  0.600nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656111(US20240067660, Compound 7)
Affinity DataKi:  0.610nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656126(US20240067660, Compound 24)
Affinity DataKi:  0.630nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552744(CHEMBL4798100 | US20240067660, Compound 22)
Affinity DataKi:  0.690nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156683(CHEMBL3793788)
Affinity DataKi:  0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156732(CHEMBL3793497)
Affinity DataKi:  0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50079412((NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 |...)
Affinity DataKi:  0.794nMAssay Description:Displacement of [125I][MePhe7]NKB from human NK3R expressed in CHO cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156787(CHEMBL3793404)
Affinity DataKi:  0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50148579(CHEMBL3770836)
Affinity DataKi:  0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156687(CHEMBL3793029)
Affinity DataKi:  0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656125(US20240067660, Compound 23)
Affinity DataKi:  0.820nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656111(US20240067660, Compound 7)
Affinity DataKi:  0.830nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656119(US20240067660, Compound 16)
Affinity DataKi:  0.830nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552739(CHEMBL4750480 | US20240067660, Compound 2)
Affinity DataKi:  0.840nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656133(US20240067660, Compound 31)
Affinity DataKi:  0.860nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156789(CHEMBL3793505)
Affinity DataKi:  0.900nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156685(CHEMBL3792412)
Affinity DataKi:  0.900nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656142(US20240067660, Compound 42)
Affinity DataKi:  0.900nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM656123(US20240067660, Compound 20)
Affinity DataKi:  0.910nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552739(CHEMBL4750480 | US20240067660, Compound 2)
Affinity DataKi:  0.990nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156691(CHEMBL3792435)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156733(CHEMBL3793296)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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