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Found 181 with Last Name = 'fournie-zaluski' and Initial = 'mc'
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50024102(((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)
Affinity DataKi:  1.90nMAssay Description:Tested for binding affinity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50084679(2-[1-(2-Carboxy-2-hydroxy-ethylcarbamoyl)-2-phenyl...)
Affinity DataKi:  11nMAssay Description:Tested for binding affinity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50422014(CHEMBL319299)
Affinity DataKi:  50nMAssay Description:Tested for binding affinity against ThermolysinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50024102(((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)
Affinity DataKi:  1.80E+3nMAssay Description:Tested for binding against ThermolysinMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050127((S)-3-(4-Hydroxy-phenyl)-2-[(2S,3R)-2-((S)-2-merca...)
Affinity DataIC50:  0.260nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050151(1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050149(1-[(S)-2-((S)-2-Mercapto-4-phenyl-butyrylamino)-pr...)
Affinity DataIC50:  0.350nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050150(1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051796((2S,5R)-5-(2-Hydroxy-phenyl)-1-{2-[(S)-2-mercapto-...)
Affinity DataIC50:  0.420nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051798((2S,5R)-5-(4-Hydroxy-phenyl)-1-{2-[(S)-3-(4-hydrox...)
Affinity DataIC50:  0.460nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051784((2S,5R)-5-(2-Hydroxy-phenyl)-1-[2-((S)-2-mercapto-...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051785((2S,5R)-1-[2-((S)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50:  0.550nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050156((S)-1-[(S)-2-((2S,3S)-2-Mercapto-3-methyl-pentanoy...)
Affinity DataIC50:  0.580nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051780((2S,5R)-5-(2-Hydroxy-phenyl)-1-{2-[(S)-3-(4-hydrox...)
Affinity DataIC50:  0.600nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051791((2S,5R)-5-(3-Hydroxy-phenyl)-1-{2-[(S)-3-(4-hydrox...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050144(1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-...)
Affinity DataIC50:  0.850nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051803((2S,5R)-1-{2-[3-(4-Chloro-phenyl)-2-mercapto-propi...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051784((2S,5R)-5-(2-Hydroxy-phenyl)-1-[2-((S)-2-mercapto-...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050125(1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051803((2S,5R)-1-{2-[3-(4-Chloro-phenyl)-2-mercapto-propi...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050158(1-[(S)-2-((R)-2-Mercapto-3-phenyl-propionylamino)-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity was tested against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050127((S)-3-(4-Hydroxy-phenyl)-2-[(2S,3R)-2-((S)-2-merca...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity was tested against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051800(1-{2-[(S)-3-(4-Hydroxy-phenyl)-2-mercapto-propiony...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051790((2S,5R)-5-(3-Hydroxy-phenyl)-1-[2-((S)-2-mercapto-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050162((S)-3-(4-Hydroxy-phenyl)-2-[(S)-2-((S)-2-mercapto-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050134(1-[2-((S)-2-Mercapto-4-phenyl-butyrylamino)-2-meth...)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051791((2S,5R)-5-(3-Hydroxy-phenyl)-1-{2-[(S)-3-(4-hydrox...)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051785((2S,5R)-1-[2-((S)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050148((S)-3-(4-Hydroxy-phenyl)-2-[(S)-2-((S)-2-mercapto-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050136(1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050146(1-[(2S,3R)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051794((2S,5R)-1-{2-[(S)-3-(4-Amino-phenyl)-2-mercapto-pr...)
Affinity DataIC50:  1.80nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50369209(CHEMBL1794012)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50024102(((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)
Affinity DataIC50:  1.90nMAssay Description:Tested for inhibition against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051796((2S,5R)-5-(2-Hydroxy-phenyl)-1-{2-[(S)-2-mercapto-...)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051799((2S,5R)-1-{2-[(S)-2-Mercapto-3-(4-methoxy-phenyl)-...)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050138((S)-3-(4-Hydroxy-phenyl)-2-[(S)-2-((S)-2-mercapto-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibitory activity was tested against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051804((2S,5R)-1-[2-((S)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50:  2.30nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050128((S)-2-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity was tested against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051790((2S,5R)-5-(3-Hydroxy-phenyl)-1-[2-((S)-2-mercapto-...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050143((S)-3-(4-Hydroxy-phenyl)-2-[(2S,3S)-2-((S)-2-merca...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051799((2S,5R)-1-{2-[(S)-2-Mercapto-3-(4-methoxy-phenyl)-...)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051786((2S,5R)-1-{2-[(S)-3-(4-Hydroxy-phenyl)-2-mercapto-...)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50407847(CHEMBL2115220)
Affinity DataIC50:  2.70nMAssay Description:In vitro inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050153((S)-3-(4-Hydroxy-phenyl)-2-[(S)-2-((S)-2-mercapto-...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory activity was tested against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050160((2-SULFANYL-3-PHENYLPROPANOYL)-PHE-TYR | (S)-3-(4-...)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity was tested against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050138((S)-3-(4-Hydroxy-phenyl)-2-[(S)-2-((S)-2-mercapto-...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50050143((S)-3-(4-Hydroxy-phenyl)-2-[(2S,3S)-2-((S)-2-merca...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity was tested against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051778((2S,5R)-1-[2-((S)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50:  3.10nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50051800(1-{2-[(S)-3-(4-Hydroxy-phenyl)-2-mercapto-propiony...)
Affinity DataIC50:  3.10nMAssay Description:In vitro inhibition of rat angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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