Affinity DataKi: 1.40nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Mixed-type inhibition of equine serum BChE using varying levels of butyrylthiocholine iodide as substrate by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 209nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 3.19E+3nMAssay Description:Mixed-type inhibition of electric eel AChE using varying levels of acetylthiocholine iodide as substrate measured for 2 mins by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 6 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human BACE-1 using SEVNLDAEFK as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus-infected insect cells using Rh-EVNLDAEFK-quencher as substrate mea...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 8.0Assay Description:In vitro AChEI activity was performed based on the modified Ellman's methodas previously reported by our group using a 96-well plate reader (BioTek E...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human BACE1 using Rh-EVNLDAEFK-quencher as substrate measured after 60 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using Rh-EVNLDAEFK-Quencher as substrate inc...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of Torpedo californica AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured for 6 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >100nMpH: 8.0 T: 2°CAssay Description:In vitro anti-AChE activity was performed based on the modified Ellman's method [Ellman et al., Biochem. Pharmacol., 71:88-95]. For this purpose, syn...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 326nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
TargetBeta-glucuronidase(Homo sapiens (Human))
Shiraz University Of Medical Sciences
Curated by ChEMBL
Shiraz University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate pre-incubated for 30 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of AChE in Sprague-Dawley rat brain homogenates using [3H]-acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 503nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair