Found 140 with Last Name = 'esmaeil' and Initial = 'n' 
Affinity DataKi: 0.690nMAssay Description:Binding affinity to human Angiotensin receptor 1More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human Angiotensin receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 10.2nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 10.5nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 13.3nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 15.7nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16.9nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
