TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 55.4nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 370nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 430nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 470nMpH: 7.4 T: 2°CAssay Description:An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 470nMpH: 7.4 T: 2°CAssay Description:An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 550nMpH: 7.0 T: 2°CAssay Description:An Homogeneous Time Resolved Fluorescence (HTRF) assay was performed in a manner similar to previous reports on HTRF protein protein assays as review...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 620nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 750nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 780nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: <1.00E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: <1.00E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: <1.00E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 1.08E+3nMpH: 7.4 T: 2°CAssay Description:An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 1.11E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 1.21E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 1.37E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 1.57E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 2.19E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 2.66E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 2.72E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 2.85E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 3.10E+3nMpH: 7.0 T: 2°CAssay Description:An Homogeneous Time Resolved Fluorescence (HTRF) assay was performed in a manner similar to previous reports on HTRF protein protein assays as review...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 3.20E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Katholieke Universiteit Leuven
US Patent
Katholieke Universiteit Leuven
US Patent
Affinity DataIC50: 3.44E+3nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume ...More data for this Ligand-Target Pair