BindingDB PrimarySearch_ki

Found 214 with Last Name = 'shan' and Initial = 'q'

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600465(CHEMBL5176682)

IC50: 0.0210nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase PC cid PC sid

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600447(CHEMBL5174561)

IC50: 0.0650nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600463(CHEMBL5200970)

IC50: 0.0750nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600454(CHEMBL5204718)

IC50: 0.0770nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600456(CHEMBL5193294)

IC50: 0.0780nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572548(CHEMBL4865743)

IC50: 0.0810nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604234(CHEMBL5179241)

IC50: 0.0900nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase PC cid PC sid

Reverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)

IC50: 0.0910nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
MMDB
PDB

3D Structure (crystal)

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572524(CHEMBL4867393)

IC50: 0.160nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572555(CHEMBL4855469)

IC50: 0.160nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572525(CHEMBL4855073)

IC50: 0.200nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600445(CHEMBL5199325)

IC50: 0.25nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600468(CHEMBL5182015)

IC50: 0.320nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600459(CHEMBL5175258)

IC50: 0.330nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604233(CHEMBL5176853)

IC50: 0.390nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572545(CHEMBL4878124)

IC50: 0.390nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Reverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572547(CHEMBL4868702)

IC50: 0.430nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)

IC50: 0.510nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details PubMed DrugBank
PDB

3D Structure (crystal)

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572549(CHEMBL4860724)

IC50: 0.540nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572546(CHEMBL4871585)

IC50: 0.560nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572553(CHEMBL4847152)

IC50: 0.580nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600464(CHEMBL5184578)

IC50: 0.630nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604247(CHEMBL5189530)

IC50: 0.670nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600450(CHEMBL5200806)

IC50: 0.730nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600451(CHEMBL5180804)

IC50: 0.790nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572552(CHEMBL4874177)

IC50: 1.10nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604231(CHEMBL5182799)

IC50: 1.20nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)

IC50: 1.20nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details PubMed DrugBank
PDB

3D Structure (crystal)

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572551(CHEMBL4858568)

IC50: 1.5nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604245(CHEMBL5185165)

IC50: 1.5nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)

IC50: 1.5nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
PDB

3D Structure (crystal)

Reverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572539(CHEMBL4872125)

IC50: 1.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572556(CHEMBL4867848)

IC50: 1.70nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604248(CHEMBL5170917)

IC50: 1.90nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600462(CHEMBL5198933)

IC50: 2nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572547(CHEMBL4868702)

IC50: 2nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604244(CHEMBL5183429)

IC50: 2.30nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50600446(CHEMBL5193685)

IC50: 2.40nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572534(CHEMBL4869642)

IC50: 2.40nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Reverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572548(CHEMBL4865743)

IC50: 2.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604249(CHEMBL5187891)

IC50: 2.5nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572528(CHEMBL4879286)

IC50: 2.60nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572527(CHEMBL4852771)

IC50: 2.90nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572531(CHEMBL4845710)

IC50: 2.90nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50604235(CHEMBL5189453)

IC50: 3nMAssay Description:Inhibition of HIV-1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-lle-Val-Gln-Lys (DABCYL)-Arg as substrate preincubated for 20 to 30 mins follo...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Reverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572562(CHEMBL4868890)

IC50: 3nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572532(CHEMBL4853765)

IC50: 3.10nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Reverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572545(CHEMBL4878124)

IC50: 3.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Reverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572554(CHEMBL4863665)

IC50: 3.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50572550(CHEMBL4855701)

IC50: 4nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 214 total ) | Next | Last >>

Filter my 214 hits

Targets 9▿
- Gag-Pol polyprotein [489-587] 97
- Reverse transcriptase/RNaseH 43
- Solute carrier family 22 member 12 18
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 14
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 14
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 8
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 8
- Platelet glycoprotein 4 6
- Heat shock protein HSP 90-alpha/90-beta 6
- ...
Publications 6▿
- Eur J Med Chem 220: (2021) 86
- Eur J Med Chem 164: 252-262 (2019) 50
- Bioorg Med Chem 64: (2022) 27
- Eur J Med Chem 233: (2022) 27
- US Patent US10584104 (2020) 18
- Eur J Med Chem 46: 1066-73 (2011) 6
Institutions 4▿
- Chinese Academy Of Medical Science And Peking Union Medical College 113
- Jiangsu Normal University 50
- Chinese Academy Of Medical Sciences And Peking Union Medical College 33
- Tianjin Institute of Pharmaceutical Research 18
Affinity: 0.021 to 1.5E+4 nM▿
- IC50 208
- Kd 6
- Affinity ≤ nM
Xtal structures: 5
Docked structures: 0
Catalog Cmpds: 9