Found 258 with Last Name = 'cooper' and Initial = 'ra' TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 4nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 169nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: <250nMAssay Description:Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <250nMAssay Description:Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <250nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <250nMAssay Description:Inhibition of CYP1A2 (unknown origin) using phenacetin O-deethylation by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 384nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 409nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 475nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 506nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 763nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
