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maximum 50k data
Found 76 with Last Name = 'knowles' and Initial = 'rg'
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346528(2,5-dihydro-1H-pyrrole-2-carboximidamide | CHEMBL1...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346520(CHEMBL1783072 | cyclobutanecarboximidamide)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086462((S)-3-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346527(CHEMBL1783092 | pyrrolidine-2-carboximidamide)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346519(CHEMBL1783071 | cyclopropanecarboximidamide)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086466((S)-3-(2-Acetimidoylamino-ethoxy)-2-amino-propioni...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086459(4-(2-Acetimidoylamino-ethoxy)-2-amino-butyric acid...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030277((R)-6-Acetimidoylamino-2-amino-hexanoic acid | CHE...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346521(CHEMBL1229853 | cyclopentanecarboximidamide)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346526(CHEMBL1783091 | tetrahydrothiophene-2-carboximidam...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086461((R)-3-(2-acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086470((R)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086459(4-(2-Acetimidoylamino-ethoxy)-2-amino-butyric acid...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086464((S)-3-(2-Acetimidoylamino-ethanesulfonyl)-2-amino-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086468((S)-3-(2-Acetimidoylamino-ethanesulfinyl)-2-amino-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346525(CHEMBL1783090 | tetrahydrofuran-2-carboximidamide)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086466((S)-3-(2-Acetimidoylamino-ethoxy)-2-amino-propioni...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086466((S)-3-(2-Acetimidoylamino-ethoxy)-2-amino-propioni...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086462((S)-3-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346531(CHEMBL1783096 | azetidine-3-carboximidamide)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030276(7-Acetimidoylamino-2-amino-heptanoic acid | CHEMBL...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030277((R)-6-Acetimidoylamino-2-amino-hexanoic acid | CHE...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086462((S)-3-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  4.00E+4nMAssay Description:Concentration required for inhibition of endothelial Nitric Oxide Synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346523(CHEMBL1783074 | piperidine-3-carboximidamide)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086461((R)-3-(2-acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346524(CHEMBL1783089 | piperidine-4-carboximidamide)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086465((R)-3-(3-Acetimidoylamino-propylsulfanyl)-2-amino-...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086468((S)-3-(2-Acetimidoylamino-ethanesulfinyl)-2-amino-...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086459(4-(2-Acetimidoylamino-ethoxy)-2-amino-butyric acid...)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030277((R)-6-Acetimidoylamino-2-amino-hexanoic acid | CHE...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086469(4-(2-Acetimidoylamino-ethanesulfinyl)-2-amino-buty...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086469(4-(2-Acetimidoylamino-ethanesulfinyl)-2-amino-buty...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030276(7-Acetimidoylamino-2-amino-heptanoic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086460(4-(2-Acetimidoylamino-ethanesulfonyl)-2-amino-buty...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086461((R)-3-(2-acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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